EIF2AK2 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description eukaryotic translation initiation factor 2-alpha kinase 2|The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] (NCBI Entrez Gene Database, 5610)
External Link https://ncbi.nlm.nih.gov/gene/5610
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Genes

479 genes differentially expressed following the EIF2AK2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
TXNDC9 thioredoxin domain containing 9 0.0158601
LCN2 lipocalin 2 0.0143332
CCL20 chemokine (C-C motif) ligand 20 0.0140178
MT1X metallothionein 1X 0.0139936
PEG3 paternally expressed 3 0.0139541
SFRP1 secreted frizzled-related protein 1 0.0139528
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.013862
IL7R interleukin 7 receptor 0.01361
LGALS13 lectin, galactoside-binding, soluble, 13 0.0135162
C3 complement component 3 0.0130919
NPY1R neuropeptide Y receptor Y1 0.0130007
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 0.0129965
METTL7A methyltransferase like 7A 0.0125464
MT1E metallothionein 1E 0.0122214
MT1F metallothionein 1F 0.0121666
METRN meteorin, glial cell differentiation regulator 0.0115413
CDC42 cell division cycle 42 0.0114131
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.0111889
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.0110971
FCGBP Fc fragment of IgG binding protein 0.0110969
CNTN1 contactin 1 0.0107318
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.0106848
MDK midkine (neurite growth-promoting factor 2) 0.0105818
CARMIL1 capping protein regulator and myosin 1 linker 1 0.0105662
PADI2 peptidyl arginine deiminase, type II 0.0105635
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.0105559
HSPB1 heat shock 27kDa protein 1 0.0104822
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.010447
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0104123
IFITM1 interferon induced transmembrane protein 1 0.0104005
MT1HL1 metallothionein 1H-like 1 0.0103305
AKAP12 A kinase (PRKA) anchor protein 12 0.0102907
CFI complement factor I 0.0102906
RAD23B RAD23 homolog B (S. cerevisiae) 0.0102535
CFB complement factor B 0.0101891
ACP5 acid phosphatase 5, tartrate resistant 0.0101835
IFI16 interferon, gamma-inducible protein 16 0.0101781
GYPC glycophorin C (Gerbich blood group) 0.0101693
JCHAIN joining chain of multimeric IgA and IgM 0.0101421
PLIN3 perilipin 3 0.0101296
XIC X chromosome inactivation center 0.0101217
CXCL8 chemokine (C-X-C motif) ligand 8 0.0101107
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.0100914
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.0100076
EIF5A eukaryotic translation initiation factor 5A 0.00999602
RNPS1 RNA binding protein S1, serine-rich domain 0.00993669
STXBP2 syntaxin binding protein 2 0.00991683
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00990702
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00985205
MT1H metallothionein 1H 0.00979508
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.0097748
LPAR6 lysophosphatidic acid receptor 6 0.00975542
CD200 CD200 molecule 0.00973264
SSBP2 single-stranded DNA binding protein 2 0.00962572
PI3 peptidase inhibitor 3, skin-derived 0.00962405
C1S complement component 1, s subcomponent 0.00962181
BAX BCL2-associated X protein 0.00961409
GPR183 G protein-coupled receptor 183 0.00958165
NDRG2 NDRG family member 2 0.00958071
BAMBI BMP and activin membrane-bound inhibitor 0.00957506
TPM4 tropomyosin 4 0.00949907
MT1G metallothionein 1G 0.00947998
TBX3 T-box 3 0.00942964
STOM stomatin 0.00937258
LAMP3 lysosomal-associated membrane protein 3 0.00929655
BTG2 BTG family, member 2 0.00924936
IL1B interleukin 1, beta 0.00924516
CHRDL1 chordin-like 1 0.00921402
FAM171A1 family with sequence similarity 171, member A1 0.00917249
ANXA1 annexin A1 0.00910381
TPM2 tropomyosin 2 (beta) 0.00909406
GLIPR1 GLI pathogenesis-related 1 0.00907763
CXCL14 chemokine (C-X-C motif) ligand 14 0.009066
SELL selectin L 0.00905823
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.00903955
RNASE6 ribonuclease, RNase A family, k6 0.00903418
C1R complement component 1, r subcomponent 0.00903395
ALB albumin 0.00902119
CD53 CD53 molecule 0.00901718
PTGES prostaglandin E synthase 0.00895846
AK4 adenylate kinase 4 0.00895599
BEX1 brain expressed, X-linked 1 0.00892424
CXCL5 chemokine (C-X-C motif) ligand 5 0.00891649
FYB1 FYN binding protein 1 0.00884573
MVP major vault protein 0.00879568
PBX1 pre-B-cell leukemia homeobox 1 0.00877517
COL4A5 collagen, type IV, alpha 5 0.00876865
TUBB2A tubulin, beta 2A class IIa 0.00874383
NELL2 NEL-like 2 (chicken) 0.00873651
SEMA4C sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C 0.00873468
GPM6B glycoprotein M6B 0.00870823
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.0086594
THBD thrombomodulin 0.00865323
MLF1 myeloid leukemia factor 1 0.00861445
S100A9 S100 calcium binding protein A9 0.00861439
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00857955
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00855473
SELENBP1 selenium binding protein 1 0.00853537
SRPX sushi-repeat containing protein, X-linked 0.00851111
RETREG3 reticulophagy regulator family member 3 0.00849436
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00848865
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.00847583
COQ8A coenzyme Q8A 0.00843723
CXCL2 chemokine (C-X-C motif) ligand 2 0.0084147
VWA5A von Willebrand factor A domain containing 5A 0.00838967
TRIP6 thyroid hormone receptor interactor 6 0.00835159
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 0.00834223
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 0.00832898
ARMT1 acidic residue methyltransferase 1 0.00828624
GAS1 growth arrest-specific 1 0.00826166
RCAN1 regulator of calcineurin 1 0.00825274
CD48 CD48 molecule 0.00820005
PDZK1IP1 PDZK1 interacting protein 1 0.00816003
RARRES1 retinoic acid receptor responder (tazarotene induced) 1 0.00815306
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 0.00813525
HSPA2 heat shock 70kDa protein 2 0.00813509
HCLS1 hematopoietic cell-specific Lyn substrate 1 0.0080948
PLIN2 perilipin 2 0.00807608
DAXX death-domain associated protein 0.00807294
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00806742
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 0.00805071
MAOA monoamine oxidase A 0.00804524
ARPC1B actin related protein 2/3 complex, subunit 1B, 41kDa 0.00802987
TSPYL5 TSPY-like 5 0.00800922
TMOD1 tropomodulin 1 0.00799942
CPB1 carboxypeptidase B1 (tissue) 0.00799447
FABP4 fatty acid binding protein 4, adipocyte 0.00798911
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 0.00796866
ISG20 interferon stimulated exonuclease gene 20kDa 0.00795718
CD248 CD248 molecule, endosialin 0.00793817
LTB lymphotoxin beta (TNF superfamily, member 3) 0.00793229
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00792059
APOH apolipoprotein H (beta-2-glycoprotein I) 0.00791465
CD300A CD300a molecule 0.00782691
DES desmin 0.00782551
FABP1 fatty acid binding protein 1, liver 0.00781506
PRPS2 phosphoribosyl pyrophosphate synthetase 2 0.00778269
DCLK1 doublecortin-like kinase 1 0.00775292
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00773687
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 0.00773369
S100P S100 calcium binding protein P 0.00771539
COG7 component of oligomeric golgi complex 7 0.00769688
RNASET2 ribonuclease T2 0.007694
GPX1 glutathione peroxidase 1 0.00768205
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00767189
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 0.0076524
GNG11 guanine nucleotide binding protein (G protein), gamma 11 0.00764983
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 0.00764808
LMO3 LIM domain only 3 (rhombotin-like 2) 0.00764801
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.00764616
BIN1 bridging integrator 1 0.00763986
BIRC3 baculoviral IAP repeat containing 3 0.00763825
PRKCQ protein kinase C, theta 0.00760797
PRKACB protein kinase, cAMP-dependent, catalytic, beta 0.00757432
RGS5 regulator of G-protein signaling 5 0.00755809
HHEX hematopoietically expressed homeobox 0.00754911
CLIC2 chloride intracellular channel 2 0.00753205
ADGRL4 adhesion G protein-coupled receptor L4 0.00751453
ADA adenosine deaminase 0.00749376
DCK deoxycytidine kinase 0.00746818
IKZF1 IKAROS family zinc finger 1 (Ikaros) 0.00745983
SORBS1 sorbin and SH3 domain containing 1 0.00744026
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00743316
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 0.00741577
AZGP1 alpha-2-glycoprotein 1, zinc-binding 0.00737734
CPB2 carboxypeptidase B2 (plasma) 0.00737569
ZNF22 zinc finger protein 22 0.00735339
FXYD3 FXYD domain containing ion transport regulator 3 0.00734902
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00734771
CRABP1 cellular retinoic acid binding protein 1 0.00734448
IL2RG interleukin 2 receptor, gamma 0.00733696
C4BPA complement component 4 binding protein, alpha 0.00732329
MDFIC MyoD family inhibitor domain containing 0.00732138
FAIM Fas apoptotic inhibitory molecule 0.00730944
CPM carboxypeptidase M 0.00730467
MMP9 matrix metallopeptidase 9 0.00729843
PDIA3 protein disulfide isomerase family A, member 3 0.00729756
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 0.00726494
NLRP2 NLR family, pyrin domain containing 2 0.007261
RGS10 regulator of G-protein signaling 10 0.00725625
MT2A metallothionein 2A 0.00725599
COMMD8 COMM domain containing 8 0.00724733
OLFM4 olfactomedin 4 0.00722384
GBAP1 glucosidase, beta, acid pseudogene 1 0.00721956
THBS1 thrombospondin 1 0.00721155
BCL3 B-cell CLL/lymphoma 3 0.00719072
RNF167 ring finger protein 167 0.0071855
SNX10 sorting nexin 10 0.00718217
TSPO translocator protein (18kDa) 0.00717773
ELOVL2 ELOVL fatty acid elongase 2 0.0071604
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.00715038
AKIRIN1 akirin 1 0.00711697
MAP3K8 mitogen-activated protein kinase kinase kinase 8 0.007114
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00711042
IL1A interleukin 1, alpha 0.00710871
TFPI2 tissue factor pathway inhibitor 2 0.00710388
NMRK1 nicotinamide riboside kinase 1 0.00708705
ACSM3 acyl-CoA synthetase medium-chain family member 3 0.0070839
ADORA2B adenosine A2b receptor 0.00707454
LY96 lymphocyte antigen 96 0.00703908
GPR137B G protein-coupled receptor 137B 0.00703132
S100A7 S100 calcium binding protein A7 0.00700575
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00698566
RSL24D1 ribosomal L24 domain containing 1 0.00696683
SOX11 SRY (sex determining region Y)-box 11 0.00696295
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1 0.00696057
IFI27 interferon, alpha-inducible protein 27 0.00694688
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein 0.00694032
IL6ST interleukin 6 signal transducer 0.00693793
CPQ carboxypeptidase Q 0.00692538
MEST mesoderm specific transcript 0.0069237
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein 0.00692024
SPON2 spondin 2, extracellular matrix protein 0.00691168
GNG12 guanine nucleotide binding protein (G protein), gamma 12 0.00690327
PIR pirin (iron-binding nuclear protein) 0.00689718
LGMN legumain 0.00688784
RELN reelin 0.00687526
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7 0.00686111
BLNK B-cell linker 0.00685487
GIMAP5 GTPase, IMAP family member 5 0.00684843
SCUBE2 signal peptide, CUB domain, EGF-like 2 0.00684768
SMAD3 SMAD family member 3 0.00684427
SLAMF7 SLAM family member 7 0.00683292
PRR5 proline rich 5 (renal) 0.00682663
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00682408
PID1 phosphotyrosine interaction domain containing 1 0.0068207
LGALS9 lectin, galactoside-binding, soluble, 9 0.00680811
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00680239
MIR22HG MIR22 host gene 0.00680031
RAP2A RAP2A, member of RAS oncogene family 0.00678634
LSP1 lymphocyte-specific protein 1 0.00676857
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00673831
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 0.00673308
TCF7 transcription factor 7 (T-cell specific, HMG-box) 0.00673282
SCGB2A2 secretoglobin, family 2A, member 2 0.00672699
PNMA1 paraneoplastic Ma antigen 1 0.006725
PDCD10 programmed cell death 10 0.00671118
PRR5L proline rich 5 like 0.00670883
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 0.0067069
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.00670488
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00670479
DIPK1A divergent protein kinase domain 1A 0.0066977
DIO1 deiodinase, iodothyronine, type I 0.0066964
CSTA cystatin A (stefin A) 0.00667681
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.00667571

decreased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 -0.02264
PCNA proliferating cell nuclear antigen -0.0173638
KLK11 kallikrein-related peptidase 11 -0.0138489
ELANE elastase, neutrophil expressed -0.0137717
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.01333
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.013265
TNS3 tensin 3 -0.0130159
GNAS GNAS complex locus -0.0122524
MSLN mesothelin -0.0121805
AMH anti-Mullerian hormone -0.0113207
KLK10 kallikrein-related peptidase 10 -0.0111166
AREG amphiregulin -0.0110586
DYNLL1 dynein, light chain, LC8-type 1 -0.0107503
IGLL1 immunoglobulin lambda-like polypeptide 1 -0.0107494
HOXB6 homeobox B6 -0.010654
PLAAT3 phospholipase A and acyltransferase 3 -0.0106058
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0105318
PRTN3 proteinase 3 -0.0103972
CLDN10 claudin 10 -0.0103157
SIK1 salt-inducible kinase 1 -0.0103078
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.0101839
BIK BCL2-interacting killer (apoptosis-inducing) -0.0101679
SC5D sterol-C5-desaturase -0.0100391
INAVA innate immunity activator -0.0100262
RRAGD Ras-related GTP binding D -0.00987966
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -0.00958177
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme -0.0095277
RALB v-ral simian leukemia viral oncogene homolog B -0.0094967
RAB11FIP1 RAB11 family interacting protein 1 (class I) -0.00935343
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 -0.00927103
CST1 cystatin SN -0.00921845
PUF60 poly-U binding splicing factor 60KDa -0.00915485
ALOX5AP arachidonate 5-lipoxygenase-activating protein -0.00914345
AZU1 azurocidin 1 -0.00912294
PNMA2 paraneoplastic Ma antigen 2 -0.00906694
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00892781
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00887381
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00886319
PNN pinin, desmosome associated protein -0.00884861
TPSAB1 tryptase alpha/beta 1 -0.00884304
AOC1 amine oxidase, copper containing 1 -0.00882517
KLK6 kallikrein-related peptidase 6 -0.00873773
TLR4 toll-like receptor 4 -0.00868894
APLP2 amyloid beta (A4) precursor-like protein 2 -0.00867101
TTC3 tetratricopeptide repeat domain 3 -0.00865942
INHBA inhibin, beta A -0.00857979
PDGFC platelet derived growth factor C -0.00856984
STK39 serine threonine kinase 39 -0.00855888
ACTA2 actin, alpha 2, smooth muscle, aorta -0.00849971
PERP PERP, TP53 apoptosis effector -0.00847827
SLC38A1 solute carrier family 38, member 1 -0.00847754
SPRED2 sprouty-related, EVH1 domain containing 2 -0.008465
PILRB paired immunoglobin-like type 2 receptor beta -0.00843068
SLIT2 slit homolog 2 (Drosophila) -0.00836252
CNPY3 canopy FGF signaling regulator 3 -0.00835558
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) -0.00833559
MXRA7 matrix-remodelling associated 7 -0.00832242
EGR1 early growth response 1 -0.00831701
COMP cartilage oligomeric matrix protein -0.0083126
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.00830125
NVL nuclear VCP-like -0.00826061
ITGB1BP1 integrin beta 1 binding protein 1 -0.00820524
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.00820514
MUC16 mucin 16, cell surface associated -0.00811642
COL11A1 collagen, type XI, alpha 1 -0.00811219
DDX42 DEAD (Asp-Glu-Ala-Asp) box helicase 42 -0.00807751
RPL10 ribosomal protein L10 -0.0080726
TESC tescalcin -0.00806275
PRPF3 pre-mRNA processing factor 3 -0.00803066
FMO2 flavin containing monooxygenase 2 (non-functional) -0.00801857
MID1 midline 1 -0.00800889
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00798845
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -0.00795864
COL5A1 collagen, type V, alpha 1 -0.00791475
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) -0.00786171
CA2 carbonic anhydrase II -0.00785275
CEMIP cell migration inducing protein, hyaluronan binding -0.00784531
KLK8 kallikrein-related peptidase 8 -0.00784486
H2AFV H2A histone family, member V -0.00784482
IFRD2 interferon-related developmental regulator 2 -0.00784376
COL9A2 collagen, type IX, alpha 2 -0.00783717
CST4 cystatin S -0.00779916
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 -0.00779298
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) -0.00778953
CRISP3 cysteine-rich secretory protein 3 -0.00774164
DMTF1 cyclin D binding myb-like transcription factor 1 -0.00767366
L1CAM L1 cell adhesion molecule -0.00764991
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -0.00760893
PDZK1 PDZ domain containing 1 -0.00760603
AEBP1 AE binding protein 1 -0.00759901
BGN biglycan -0.00759832
ANOS1 anosmin 1 -0.00757337
ZMAT3 zinc finger, matrin-type 3 -0.0075629
GLA galactosidase, alpha -0.0075427
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.00745301
CDA cytidine deaminase -0.00743994
NXN nucleoredoxin -0.00742028
PDZD2 PDZ domain containing 2 -0.00740826
KLK7 kallikrein-related peptidase 7 -0.00739657
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1 -0.007385
ANXA3 annexin A3 -0.00737752
GMDS GDP-mannose 4,6-dehydratase -0.00731511
HNRNPH3 heterogeneous nuclear ribonucleoprotein H3 (2H9) -0.00729762
CALML5 calmodulin-like 5 -0.00729064
PAXBP1 PAX3 and PAX7 binding protein 1 -0.00728258
NECTIN3 nectin cell adhesion molecule 3 -0.00727537
FGFR1 fibroblast growth factor receptor 1 -0.00726229
ITM2A integral membrane protein 2A -0.0072395
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -0.00722334
CASP2 caspase 2, apoptosis-related cysteine peptidase -0.00720594
ZDHHC11 zinc finger, DHHC-type containing 11 -0.00719371
STIP1 stress-induced phosphoprotein 1 -0.00718966
BHLHE41 basic helix-loop-helix family, member e41 -0.00718794
LRP2 low density lipoprotein receptor-related protein 2 -0.00717568
PER2 period circadian clock 2 -0.00716522
WWC3 WWC family member 3 -0.00712692
ZNF185 zinc finger protein 185 (LIM domain) -0.00712656
CXCL3 chemokine (C-X-C motif) ligand 3 -0.00708213
ESM1 endothelial cell-specific molecule 1 -0.00707711
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B -0.00707527
TRIM29 tripartite motif containing 29 -0.00702547
CHKA choline kinase alpha -0.00702315
GSTP1 glutathione S-transferase pi 1 -0.00701945
CTSV cathepsin V -0.00701127
TYMS thymidylate synthetase -0.00698659
RANBP2 RAN binding protein 2 -0.00693938
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00693339
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -0.00688365
IQGAP1 IQ motif containing GTPase activating protein 1 -0.00687875
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00686983
PIEZO2 piezo-type mechanosensitive ion channel component 2 -0.00685655
PON3 paraoxonase 3 -0.00685074
CLC Charcot-Leyden crystal galectin -0.00681379
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4 -0.00680705
RGL2 ral guanine nucleotide dissociation stimulator-like 2 -0.00679593
HACD1 3-hydroxyacyl-CoA dehydratase 1 -0.00678785
PFKP phosphofructokinase, platelet -0.00678434
IVNS1ABP influenza virus NS1A binding protein -0.00675799
ZNF804A zinc finger protein 804A -0.00675403
CYTL1 cytokine-like 1 -0.0067362
ATAD2 ATPase family, AAA domain containing 2 -0.00671171
EPS8L2 EPS8-like 2 -0.00670172
NPR3 natriuretic peptide receptor 3 -0.00668715
SLPI secretory leukocyte peptidase inhibitor -0.0066811
CCN3 cellular communication network factor 3 -0.00667599
ERBB3 erb-b2 receptor tyrosine kinase 3 -0.00667451
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 -0.00666352
CST6 cystatin E/M -0.00665357
PKD1P1 polycystic kidney disease 1 (autosomal dominant) pseudogene 1 -0.00663708
WT1 Wilms tumor 1 -0.00663493
MMP2 matrix metallopeptidase 2 -0.00663033
HOMER1 homer scaffolding protein 1 -0.00662533
PDE10A phosphodiesterase 10A -0.00661509
PCDH9 protocadherin 9 -0.0066109
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.00658652
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00658068
LGR4 leucine-rich repeat containing G protein-coupled receptor 4 -0.0065563
LYST lysosomal trafficking regulator -0.00650993
DSG1 desmoglein 1 -0.00648806
CRYAB crystallin, alpha B -0.00648762
SH3BP4 SH3-domain binding protein 4 -0.00646682
HBB hemoglobin, beta -0.00646437
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.00645803
YBX3 Y box binding protein 3 -0.00641719
MCM4 minichromosome maintenance complex component 4 -0.00641432
TACC3 transforming, acidic coiled-coil containing protein 3 -0.00640296
THBS4 thrombospondin 4 -0.00639904
TCTA T-cell leukemia translocation altered -0.00639787
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -0.00639629
S100A10 S100 calcium binding protein A10 -0.00638211
CDS2 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2 -0.00637198
COCH cochlin -0.00635289
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.00634771
CRLF1 cytokine receptor-like factor 1 -0.00632142
CRNN cornulin -0.00629178
CLTB clathrin, light chain B -0.006288
IRS2 insulin receptor substrate 2 -0.00627804
SLBP stem-loop binding protein -0.00625482
PTPN3 protein tyrosine phosphatase, non-receptor type 3 -0.00624505
S100A4 S100 calcium binding protein A4 -0.00623069
SCGB1D2 secretoglobin, family 1D, member 2 -0.0062207
ITSN2 intersectin 2 -0.00620565
PRPF4 pre-mRNA processing factor 4 -0.00618593
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00618576
TMC5 transmembrane channel-like 5 -0.00617704
DMXL2 Dmx-like 2 -0.00617203
DLG1 discs, large homolog 1 (Drosophila) -0.00615898
MEIS1 Meis homeobox 1 -0.00615414
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) -0.00615199
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae) -0.00613905
NXF1 nuclear RNA export factor 1 -0.00611079
PRKDC protein kinase, DNA-activated, catalytic polypeptide -0.00610113
CLEC11A C-type lectin domain family 11, member A -0.00608615
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.00608296
FOCAD focadhesin -0.00608282
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00608239
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00607974
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B -0.0060773
USP34 ubiquitin specific peptidase 34 -0.00607603
DSP desmoplakin -0.00606447
NARS2 asparaginyl-tRNA synthetase 2, mitochondrial (putative) -0.00605939
PWP2 PWP2 periodic tryptophan protein homolog (yeast) -0.00605661
ADGRF5 adhesion G protein-coupled receptor F5 -0.00605074
DEFB1 defensin, beta 1 -0.00605071
CPA3 carboxypeptidase A3 (mast cell) -0.00604918
KLK5 kallikrein-related peptidase 5 -0.00603326
COL8A1 collagen, type VIII, alpha 1 -0.00603128
IL10RB interleukin 10 receptor, beta -0.00602668
ST18 suppression of tumorigenicity 18, zinc finger -0.00600791
SRSF7 serine/arginine-rich splicing factor 7 -0.00600605
CBX1 chromobox homolog 1 -0.00600053
SCRIB scribbled planar cell polarity protein -0.00599677
PHACTR2 phosphatase and actin regulator 2 -0.00599444
SIRT3 sirtuin 3 -0.00598159
MEN1 multiple endocrine neoplasia I -0.00597718
CYBA cytochrome b-245, alpha polypeptide -0.00597611
ARPP19 cAMP-regulated phosphoprotein, 19kDa -0.00595096
KIDINS220 kinase D-interacting substrate, 220kDa -0.00595087
TUBB4B tubulin, beta 4B class IVb -0.0059383
CAPN2 calpain 2, (m/II) large subunit -0.00593008
DAPK1 death-associated protein kinase 1 -0.00592647
ANO1 anoctamin 1, calcium activated chloride channel -0.00591971
VPREB1 pre-B lymphocyte 1 -0.00590925
UBE2L6 ubiquitin-conjugating enzyme E2L 6 -0.00590552
EYA2 EYA transcriptional coactivator and phosphatase 2 -0.0058994
MRPL9 mitochondrial ribosomal protein L9 -0.00589645
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa -0.00589482
MARCKSL1 MARCKS-like 1 -0.00589086
MED14 mediator complex subunit 14 -0.00588919
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) -0.00588509
PSCA prostate stem cell antigen -0.00586477
SON SON DNA binding protein -0.00585458
HBD hemoglobin, delta -0.00585347
TMEM176B transmembrane protein 176B -0.00584747