| Dataset | PhosphoSitePlus Substrates of Kinases |
| Category | physical interactions |
| Type | kinase |
| Description | eukaryotic translation initiation factor 2 alpha kinase 4|This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. [provided by RefSeq, Mar 2014] (NCBI Entrez Gene Database, 440275) |
| External Link | http://www.ncbi.nlm.nih.gov/gene/440275 |
| Similar Terms | |
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2 substrates of the kinase EIF2AK4 from the curated PhosphoSitePlus Substrates of Kinases dataset.
