| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | eukaryotic translation initiation factor 4E|The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of cellular mRNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the mRNA. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 1977) |
| External Link | https://ncbi.nlm.nih.gov/gene/1977 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the EIF4E gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0301508 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.0172706 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0165779 |
| PCNA | proliferating cell nuclear antigen | 0.0153536 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.013697 |
| MEF2C | myocyte enhancer factor 2C | 0.0135461 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.0123555 |
| CA2 | carbonic anhydrase II | 0.0117166 |
| SCD5 | stearoyl-CoA desaturase 5 | 0.0116451 |
| ANOS1 | anosmin 1 | 0.0112623 |
| DCXR | dicarbonyl/L-xylulose reductase | 0.0110482 |
| CSTA | cystatin A (stefin A) | 0.0102616 |
| OPHN1 | oligophrenin 1 | 0.00996869 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00993749 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.00993478 |
| AK4 | adenylate kinase 4 | 0.00979105 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.00971143 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | 0.0095594 |
| CYB5A | cytochrome b5 type A (microsomal) | 0.00947684 |
| POLE3 | polymerase (DNA directed), epsilon 3, accessory subunit | 0.00947016 |
| TMEM45A | transmembrane protein 45A | 0.00902875 |
| TCTN2 | tectonic family member 2 | 0.00894997 |
| PIP | prolactin-induced protein | 0.00885315 |
| PLPBP | pyridoxal phosphate binding protein | 0.00883627 |
| APMAP | adipocyte plasma membrane associated protein | 0.00881807 |
| ZNF589 | zinc finger protein 589 | 0.00879231 |
| NRN1 | neuritin 1 | 0.00873654 |
| AQP9 | aquaporin 9 | 0.00865297 |
| OXA1L | oxidase (cytochrome c) assembly 1-like | 0.00862465 |
| S100A7 | S100 calcium binding protein A7 | 0.00850979 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 0.0083751 |
| CXADR | coxsackie virus and adenovirus receptor | 0.00836195 |
| CLC | Charcot-Leyden crystal galectin | 0.00833194 |
| FABP7 | fatty acid binding protein 7, brain | 0.00833047 |
| C9 | complement component 9 | 0.00831035 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00829029 |
| BID | BH3 interacting domain death agonist | 0.00824758 |
| STOM | stomatin | 0.00823706 |
| F12 | coagulation factor XII (Hageman factor) | 0.0081935 |
| POLE2 | polymerase (DNA directed), epsilon 2, accessory subunit | 0.00816705 |
| FASN | fatty acid synthase | 0.00796047 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00788424 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00786437 |
| ARG1 | arginase 1 | 0.00785234 |
| TMSB15A | thymosin beta 15a | 0.00784816 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | 0.00781426 |
| SELL | selectin L | 0.0078002 |
| GLTP | glycolipid transfer protein | 0.00779073 |
| CHPT1 | choline phosphotransferase 1 | 0.00776989 |
| CENPE | centromere protein E, 312kDa | 0.00771782 |
| SLC25A15 | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 | 0.00771011 |
| SET | SET nuclear proto-oncogene | 0.00761324 |
| NPM3 | nucleophosmin/nucleoplasmin 3 | 0.00753276 |
| GPX1 | glutathione peroxidase 1 | 0.00752518 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | 0.00750313 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00749433 |
| MTARC1 | mitochondrial amidoxime reducing component 1 | 0.00745233 |
| THAP11 | THAP domain containing 11 | 0.00742482 |
| MPO | myeloperoxidase | 0.0074099 |
| CTSS | cathepsin S | 0.00740041 |
| PIPOX | pipecolic acid oxidase | 0.00737461 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | 0.00736086 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | 0.00735449 |
| CYTL1 | cytokine-like 1 | 0.00731698 |
| CYP2C9 | cytochrome P450, family 2, subfamily C, polypeptide 9 | 0.00731678 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | 0.00727156 |
| NES | nestin | 0.00723926 |
| UGT2B28 | UDP glucuronosyltransferase 2 family, polypeptide B28 | 0.00720622 |
| CYP1A2 | cytochrome P450, family 1, subfamily A, polypeptide 2 | 0.0071842 |
| CFHR2 | complement factor H-related 2 | 0.00717345 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.00714669 |
| ADI1 | acireductone dioxygenase 1 | 0.00713322 |
| RMI1 | RecQ mediated genome instability 1 | 0.00712322 |
| CYP4F3 | cytochrome P450, family 4, subfamily F, polypeptide 3 | 0.00712133 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.00710944 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | 0.00709526 |
| CRP | C-reactive protein, pentraxin-related | 0.00709371 |
| CD52 | CD52 molecule | 0.0070599 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.00704507 |
| IKBKE | inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon | 0.00697524 |
| DIPK1A | divergent protein kinase domain 1A | 0.00697413 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.00694291 |
| HSD17B4 | hydroxysteroid (17-beta) dehydrogenase 4 | 0.00693419 |
| ANXA6 | annexin A6 | 0.00691812 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 0.00691745 |
| KAT7 | K(lysine) acetyltransferase 7 | 0.00688332 |
| CDC42 | cell division cycle 42 | 0.00688188 |
| FAM234B | family with sequence similarity 234 member B | 0.00686589 |
| ADORA2B | adenosine A2b receptor | 0.00681904 |
| SNRPB | small nuclear ribonucleoprotein polypeptides B and B1 | 0.0067973 |
| CDKN1B | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | 0.00679271 |
| CPOX | coproporphyrinogen oxidase | 0.00679256 |
| BIRC5 | baculoviral IAP repeat containing 5 | 0.00678837 |
| CDCA4 | cell division cycle associated 4 | 0.00677662 |
| DNASE1L3 | deoxyribonuclease I-like 3 | 0.0067442 |
| ACAT2 | acetyl-CoA acetyltransferase 2 | 0.00673633 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.00672746 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.00671082 |
| TDP1 | tyrosyl-DNA phosphodiesterase 1 | 0.00669768 |
| UGT2B4 | UDP glucuronosyltransferase 2 family, polypeptide B4 | 0.0066747 |
| RPS9 | ribosomal protein S9 | 0.00665655 |
| UGT2B17 | UDP glucuronosyltransferase 2 family, polypeptide B17 | 0.00664559 |
| RPS5 | ribosomal protein S5 | 0.00657824 |
| CREBL2 | cAMP responsive element binding protein-like 2 | 0.00657112 |
| LMNB1 | lamin B1 | 0.00655403 |
| CLDN8 | claudin 8 | 0.00654429 |
| DHFR | dihydrofolate reductase | 0.00652194 |
| SH3BGRL | SH3 domain binding glutamate-rich protein like | 0.00649381 |
| CNN2 | calponin 2 | 0.00648588 |
| JCHAIN | joining chain of multimeric IgA and IgM | 0.00648083 |
| ASH2L | ash2 (absent, small, or homeotic)-like (Drosophila) | 0.00646174 |
| PADI2 | peptidyl arginine deiminase, type II | 0.00644727 |
| MYBPC1 | myosin binding protein C, slow type | 0.00641518 |
| PRIM1 | primase, DNA, polypeptide 1 (49kDa) | 0.00639297 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.00638484 |
| RPA3 | replication protein A3, 14kDa | 0.00637435 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | 0.00637204 |
| FABP1 | fatty acid binding protein 1, liver | 0.00636513 |
| RAB4A | RAB4A, member RAS oncogene family | 0.00635626 |
| FBL | fibrillarin | 0.00634708 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.00634546 |
| NVL | nuclear VCP-like | 0.006337 |
| UGT2B15 | UDP glucuronosyltransferase 2 family, polypeptide B15 | 0.00632408 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | 0.00627389 |
| CYP2C18 | cytochrome P450, family 2, subfamily C, polypeptide 18 | 0.00625297 |
| GTF3A | general transcription factor IIIA | 0.00625059 |
| SPINK2 | serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) | 0.00624905 |
| KCTD12 | potassium channel tetramerization domain containing 12 | 0.00623399 |
| TMX1 | thioredoxin-related transmembrane protein 1 | 0.0062339 |
| CRELD2 | cysteine-rich with EGF-like domains 2 | 0.00622442 |
| TTTY15 | testis-specific transcript, Y-linked 15 (non-protein coding) | 0.00622174 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.00621486 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0062107 |
| NRG1 | neuregulin 1 | 0.00618971 |
| DNMT3B | DNA (cytosine-5-)-methyltransferase 3 beta | 0.00618949 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | 0.00618017 |
| F2R | coagulation factor II (thrombin) receptor | 0.00613365 |
| MEFV | Mediterranean fever | 0.00613027 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.00610109 |
| SRPX | sushi-repeat containing protein, X-linked | 0.00609595 |
| SPCS3 | signal peptidase complex subunit 3 homolog (S. cerevisiae) | 0.00609484 |
| EMP3 | epithelial membrane protein 3 | 0.00609348 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | 0.00609125 |
| SOX11 | SRY (sex determining region Y)-box 11 | 0.00608079 |
| HPX | hemopexin | 0.00606215 |
| ELK1 | ELK1, member of ETS oncogene family | 0.00605918 |
| SEPHS1 | selenophosphate synthetase 1 | 0.00603966 |
| PRPS1 | phosphoribosyl pyrophosphate synthetase 1 | 0.00602869 |
| TOR1A | torsin family 1, member A (torsin A) | 0.00602366 |
| SIVA1 | SIVA1, apoptosis-inducing factor | 0.00600855 |
| CDK14 | cyclin-dependent kinase 14 | 0.00600213 |
| EIF3I | eukaryotic translation initiation factor 3, subunit I | 0.00599557 |
| HAL | histidine ammonia-lyase | 0.00598718 |
| SLC35A5 | solute carrier family 35, member A5 | 0.00598595 |
| TYRP1 | tyrosinase-related protein 1 | 0.00597824 |
| RPL14 | ribosomal protein L14 | 0.00596603 |
| CCDC85B | coiled-coil domain containing 85B | 0.00596535 |
| MBL2 | mannose-binding lectin (protein C) 2, soluble | 0.00595369 |
| SLC15A2 | solute carrier family 15 (oligopeptide transporter), member 2 | 0.00594826 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | 0.00594818 |
| MPHOSPH6 | M-phase phosphoprotein 6 | 0.0059225 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | 0.00591164 |
| PRR7 | proline rich 7 (synaptic) | 0.00591159 |
| DCPS | decapping enzyme, scavenger | 0.0059065 |
| SAA4 | serum amyloid A4, constitutive | 0.00587194 |
| METTL7A | methyltransferase like 7A | 0.0058713 |
| VIPR1 | vasoactive intestinal peptide receptor 1 | 0.00586379 |
| UBE2G2 | ubiquitin-conjugating enzyme E2G 2 | 0.00585865 |
| RPL36 | ribosomal protein L36 | 0.00585645 |
| POU5F1B | POU class 5 homeobox 1B | 0.00585132 |
| TMEM9B | TMEM9 domain family, member B | 0.00585061 |
| KCNJ2 | potassium channel, inwardly rectifying subfamily J, member 2 | 0.00584333 |
| TBC1D4 | TBC1 domain family, member 4 | 0.00584195 |
| S100A9 | S100 calcium binding protein A9 | 0.00582939 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00580198 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.00578934 |
| LIMD1 | LIM domains containing 1 | 0.00578592 |
| FERMT1 | fermitin family member 1 | 0.00578334 |
| SMCO4 | single-pass membrane protein with coiled-coil domains 4 | 0.00578091 |
| SRSF6 | serine/arginine-rich splicing factor 6 | 0.00576553 |
| NANOG | Nanog homeobox | 0.00575341 |
| FBP1 | fructose-1,6-bisphosphatase 1 | 0.00574248 |
| MAT2B | methionine adenosyltransferase II, beta | 0.00573998 |
| S100A8 | S100 calcium binding protein A8 | 0.00573088 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00573077 |
| TTN | titin | 0.00572997 |
| ABHD10 | abhydrolase domain containing 10 | 0.00572542 |
| CLCA2 | chloride channel accessory 2 | 0.00572501 |
| KMO | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 0.00571455 |
| DHDDS | dehydrodolichyl diphosphate synthase | 0.00571373 |
| SLC17A4 | solute carrier family 17, member 4 | 0.00571336 |
| SLC30A3 | solute carrier family 30 (zinc transporter), member 3 | 0.00570166 |
| RELN | reelin | 0.00569998 |
| NEIL3 | nei endonuclease VIII-like 3 (E. coli) | 0.00569778 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | 0.00569081 |
| INSIG1 | insulin induced gene 1 | 0.00565931 |
| CBR3 | carbonyl reductase 3 | 0.00565768 |
| GGH | gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) | 0.0056566 |
| OSBPL11 | oxysterol binding protein-like 11 | 0.00565636 |
| DUOX1 | dual oxidase 1 | 0.00564769 |
| PIMREG | PICALM interacting mitotic regulator | 0.00563762 |
| CD27 | CD27 molecule | 0.00563638 |
| HOPX | HOP homeobox | 0.00562162 |
| CRIP2 | cysteine-rich protein 2 | 0.00560779 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | 0.00559915 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.005592 |
| LST1 | leukocyte specific transcript 1 | 0.00558419 |
| MRPS27 | mitochondrial ribosomal protein S27 | 0.00558246 |
| TMEM230 | transmembrane protein 230 | 0.00558134 |
| GTPBP3 | GTP binding protein 3 (mitochondrial) | 0.00557112 |
| SLC38A4 | solute carrier family 38, member 4 | 0.00555857 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.00554794 |
| SLC27A5 | solute carrier family 27 (fatty acid transporter), member 5 | 0.0055343 |
| RNH1 | ribonuclease/angiogenin inhibitor 1 | 0.00552674 |
| CALML3 | calmodulin-like 3 | 0.005523 |
| PPID | peptidylprolyl isomerase D | 0.0055079 |
| PLIN3 | perilipin 3 | 0.00549149 |
| RNASE2 | ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) | 0.00548865 |
| BHMT | betaine--homocysteine S-methyltransferase | 0.00547687 |
| LOR | loricrin | 0.00546184 |
| CD36 | CD36 molecule (thrombospondin receptor) | 0.00545707 |
| CEP43 | centrosomal protein 43 | 0.00545173 |
| RPS17 | ribosomal protein S17 | 0.00544588 |
| CLEC7A | C-type lectin domain family 7, member A | 0.00544315 |
| SH3BP4 | SH3-domain binding protein 4 | 0.00543032 |
| PRKY | protein kinase, Y-linked, pseudogene | 0.00542793 |
| CASP2 | caspase 2, apoptosis-related cysteine peptidase | 0.00541844 |
| HAUS5 | HAUS augmin-like complex, subunit 5 | 0.00541715 |
| CD302 | CD302 molecule | 0.00541541 |
| GAS1 | growth arrest-specific 1 | 0.00541381 |
| TPM2 | tropomyosin 2 (beta) | 0.00541026 |
| BCL11A | B-cell CLL/lymphoma 11A (zinc finger protein) | 0.00540431 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.0054031 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.00538722 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00537015 |
| ANG | angiogenin, ribonuclease, RNase A family, 5 | 0.00536792 |
| HINT1 | histidine triad nucleotide binding protein 1 | 0.00536242 |
| GAL | galanin/GMAP prepropeptide | 0.00536 |
| TMEM38B | transmembrane protein 38B | 0.00535438 |
| NINJ1 | ninjurin 1 | 0.00534536 |
| CDC42SE1 | CDC42 small effector 1 | 0.00533301 |
| APCS | amyloid P component, serum | 0.00531614 |
| AKR1A1 | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 0.00531478 |
| CFHR4 | complement factor H-related 4 | 0.00531399 |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 | 0.00530151 |
| TAT | tyrosine aminotransferase | 0.00529946 |
| NQO2 | NAD(P)H dehydrogenase, quinone 2 | 0.00529418 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) | 0.00528634 |
| H2AFV | H2A histone family, member V | 0.00528045 |
| CARD8 | caspase recruitment domain family, member 8 | 0.00527868 |
| Symbol | Name | Standardized Value |
|---|---|---|
| XIC | X chromosome inactivation center | -0.0231059 |
| CHGB | chromogranin B | -0.0164274 |
| PCP4 | Purkinje cell protein 4 | -0.0158094 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0147694 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0142779 |
| SCG5 | secretogranin V | -0.0142137 |
| KRT19 | keratin 19, type I | -0.0134978 |
| ATF3 | activating transcription factor 3 | -0.0132003 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.0128881 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0124466 |
| GRIA2 | glutamate receptor, ionotropic, AMPA 2 | -0.0123491 |
| AGR2 | anterior gradient 2 | -0.0121741 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.0113619 |
| CADM1 | cell adhesion molecule 1 | -0.0113075 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0113012 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0112801 |
| PRAME | preferentially expressed antigen in melanoma | -0.0110006 |
| PEG10 | paternally expressed 10 | -0.0108159 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0105191 |
| AOC1 | amine oxidase, copper containing 1 | -0.0104605 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0104292 |
| VEGFA | vascular endothelial growth factor A | -0.0103881 |
| PLIN2 | perilipin 2 | -0.0103732 |
| MMP7 | matrix metallopeptidase 7 | -0.0102529 |
| CFB | complement factor B | -0.0102423 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0101523 |
| ASS1 | argininosuccinate synthase 1 | -0.0101522 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | -0.0101272 |
| KIF2C | kinesin family member 2C | -0.0100589 |
| EMP1 | epithelial membrane protein 1 | -0.0100557 |
| KCNK3 | potassium channel, two pore domain subfamily K, member 3 | -0.00984926 |
| SYT1 | synaptotagmin I | -0.0098415 |
| CCN3 | cellular communication network factor 3 | -0.00983214 |
| WT1 | Wilms tumor 1 | -0.00975888 |
| RGS16 | regulator of G-protein signaling 16 | -0.00963584 |
| MFAP5 | microfibrillar associated protein 5 | -0.00958351 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.00957811 |
| IFI44L | interferon-induced protein 44-like | -0.00956199 |
| DLK1 | delta-like 1 homolog (Drosophila) | -0.0094983 |
| CALB1 | calbindin 1, 28kDa | -0.00948253 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.00945949 |
| MAGEA3 | melanoma antigen family A3 | -0.00945637 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00945559 |
| COL15A1 | collagen, type XV, alpha 1 | -0.0093769 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0092937 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00921112 |
| KRT18 | keratin 18, type I | -0.0091254 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.00903476 |
| SST | somatostatin | -0.00898842 |
| NRCAM | neuronal cell adhesion molecule | -0.00898395 |
| BEX1 | brain expressed, X-linked 1 | -0.00898189 |
| S100P | S100 calcium binding protein P | -0.00893878 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | -0.00887586 |
| MX1 | MX dynamin-like GTPase 1 | -0.00886028 |
| CUX1 | cut-like homeobox 1 | -0.00878414 |
| DHRS2 | dehydrogenase/reductase (SDR family) member 2 | -0.00876984 |
| GAB2 | GRB2-associated binding protein 2 | -0.00876462 |
| DYNLL1 | dynein, light chain, LC8-type 1 | -0.00872957 |
| RCAN1 | regulator of calcineurin 1 | -0.00870744 |
| SEZ6L2 | seizure related 6 homolog (mouse)-like 2 | -0.00869666 |
| CCNA2 | cyclin A2 | -0.00868434 |
| EGR1 | early growth response 1 | -0.00866326 |
| NMNAT2 | nicotinamide nucleotide adenylyltransferase 2 | -0.00865225 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 | -0.00862147 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.00860792 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.00859871 |
| UPP1 | uridine phosphorylase 1 | -0.00848089 |
| PDGFD | platelet derived growth factor D | -0.00845323 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00842896 |
| TNS3 | tensin 3 | -0.00832292 |
| MEIS2 | Meis homeobox 2 | -0.00825304 |
| NEFM | neurofilament, medium polypeptide | -0.00824305 |
| STC2 | stanniocalcin 2 | -0.00822349 |
| SPATA20 | spermatogenesis associated 20 | -0.00821659 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 | -0.00819611 |
| MITF | microphthalmia-associated transcription factor | -0.00817435 |
| BAG3 | BCL2-associated athanogene 3 | -0.00813106 |
| NFASC | neurofascin | -0.0081065 |
| REG1A | regenerating islet-derived 1 alpha | -0.00809069 |
| CPE | carboxypeptidase E | -0.00808714 |
| FBN2 | fibrillin 2 | -0.00808663 |
| EPCAM | epithelial cell adhesion molecule | -0.00807006 |
| MYRF | myelin regulatory factor | -0.00805397 |
| MINK1 | misshapen-like kinase 1 | -0.00804364 |
| PAM | peptidylglycine alpha-amidating monooxygenase | -0.00798988 |
| TFF1 | trefoil factor 1 | -0.00798749 |
| BRD4 | bromodomain containing 4 | -0.00796943 |
| MATN2 | matrilin 2 | -0.00794921 |
| SMAD7 | SMAD family member 7 | -0.00793297 |
| LCN2 | lipocalin 2 | -0.00791201 |
| TPBG | trophoblast glycoprotein | -0.00790902 |
| QPRT | quinolinate phosphoribosyltransferase | -0.00790687 |
| H1-0 | H1.0 linker histone | -0.00786611 |
| CXCL11 | chemokine (C-X-C motif) ligand 11 | -0.00785595 |
| SNAI2 | snail family zinc finger 2 | -0.00782331 |
| RHOB | ras homolog family member B | -0.00781903 |
| CNTN1 | contactin 1 | -0.00774078 |
| PROM1 | prominin 1 | -0.00771534 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 | -0.00770471 |
| PTK2 | protein tyrosine kinase 2 | -0.00763196 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | -0.00761463 |
| MEG3 | maternally expressed 3 (non-protein coding) | -0.00756841 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.00756802 |
| PEG3 | paternally expressed 3 | -0.00754431 |
| HMGN3 | high mobility group nucleosomal binding domain 3 | -0.00753674 |
| GBAP1 | glucosidase, beta, acid pseudogene 1 | -0.00746641 |
| TMEM176B | transmembrane protein 176B | -0.00735597 |
| UCP2 | uncoupling protein 2 (mitochondrial, proton carrier) | -0.00734178 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00733747 |
| MSX1 | msh homeobox 1 | -0.00732823 |
| LMO2 | LIM domain only 2 (rhombotin-like 1) | -0.00732532 |
| TENM3 | teneurin transmembrane protein 3 | -0.00727898 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00727435 |
| DNAJC6 | DnaJ (Hsp40) homolog, subfamily C, member 6 | -0.00727197 |
| TAC1 | tachykinin, precursor 1 | -0.0072485 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00723474 |
| CRISP3 | cysteine-rich secretory protein 3 | -0.00723035 |
| NDRG1 | N-myc downstream regulated 1 | -0.00722431 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.00718781 |
| HTR2B | 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled | -0.00718751 |
| RASA4 | RAS p21 protein activator 4 | -0.00718607 |
| AMDHD2 | amidohydrolase domain containing 2 | -0.00715359 |
| PCSK1 | proprotein convertase subtilisin/kexin type 1 | -0.00714369 |
| CHGA | chromogranin A | -0.00708854 |
| USP47 | ubiquitin specific peptidase 47 | -0.00705073 |
| LAMB1 | laminin, beta 1 | -0.00704736 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00704272 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00703973 |
| TTC39A | tetratricopeptide repeat domain 39A | -0.00702889 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.00701855 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00701332 |
| NFKBIE | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon | -0.00701269 |
| ESR1 | estrogen receptor 1 | -0.00696596 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0069656 |
| SMARCC2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 | -0.00696422 |
| MGP | matrix Gla protein | -0.0069566 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | -0.00694224 |
| MAGEA12 | melanoma antigen family A12 | -0.00694205 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | -0.00691053 |
| HOXC6 | homeobox C6 | -0.0069072 |
| GEM | GTP binding protein overexpressed in skeletal muscle | -0.00690529 |
| SV2C | synaptic vesicle glycoprotein 2C | -0.00688997 |
| INPPL1 | inositol polyphosphate phosphatase-like 1 | -0.00688659 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | -0.00688579 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00683183 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.00682825 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.00682754 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | -0.00680533 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00677743 |
| VGLL4 | vestigial-like family member 4 | -0.00677716 |
| REG3A | regenerating islet-derived 3 alpha | -0.00676342 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | -0.00673577 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | -0.00671785 |
| ZDHHC11 | zinc finger, DHHC-type containing 11 | -0.00670853 |
| LPIN1 | lipin 1 | -0.00670452 |
| SELE | selectin E | -0.0066882 |
| FGG | fibrinogen gamma chain | -0.00668451 |
| APOD | apolipoprotein D | -0.006671 |
| MPRIP | myosin phosphatase Rho interacting protein | -0.00666595 |
| FKBP9 | FK506 binding protein 9, 63 kDa | -0.00665222 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.00664948 |
| IFI44 | interferon-induced protein 44 | -0.00663336 |
| ANK2 | ankyrin 2, neuronal | -0.00660726 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.00657361 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.00654346 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.00653877 |
| SFN | stratifin | -0.00653502 |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 | -0.00653077 |
| KRT8 | keratin 8, type II | -0.00650044 |
| GMPR | guanosine monophosphate reductase | -0.0064728 |
| CEBPB | CCAAT/enhancer binding protein (C/EBP), beta | -0.00647028 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.00643651 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | -0.00641674 |
| FOLR1 | folate receptor 1 (adult) | -0.00641481 |
| IFRD1 | interferon-related developmental regulator 1 | -0.00640221 |
| STC1 | stanniocalcin 1 | -0.00639189 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00636498 |
| CX3CL1 | chemokine (C-X3-C motif) ligand 1 | -0.00634801 |
| SPEN | spen family transcriptional repressor | -0.00633675 |
| MGLL | monoglyceride lipase | -0.00632949 |
| PPM1H | protein phosphatase, Mg2+/Mn2+ dependent, 1H | -0.0063253 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | -0.00629916 |
| CHD4 | chromodomain helicase DNA binding protein 4 | -0.00629813 |
| SOBP | sine oculis binding protein homolog (Drosophila) | -0.00628896 |
| IFI35 | interferon-induced protein 35 | -0.00628382 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.00628336 |
| ABAT | 4-aminobutyrate aminotransferase | -0.00627519 |
| ZFP36 | ZFP36 ring finger protein | -0.00626325 |
| TUBA4A | tubulin, alpha 4a | -0.0062503 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.00624731 |
| KMT5B | lysine methyltransferase 5B | -0.00624409 |
| CPM | carboxypeptidase M | -0.00624183 |
| TARS1 | threonyl-tRNA synthetase 1 | -0.00623311 |
| ISG20 | interferon stimulated exonuclease gene 20kDa | -0.00622858 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.00621813 |
| MUC16 | mucin 16, cell surface associated | -0.0061945 |
| GDF15 | growth differentiation factor 15 | -0.00618588 |
| COL6A2 | collagen, type VI, alpha 2 | -0.00616565 |
| BTF3P11 | basic transcription factor 3 pseudogene 11 | -0.00614776 |
| CCNE1 | cyclin E1 | -0.00613531 |
| DAAM2 | dishevelled associated activator of morphogenesis 2 | -0.00613501 |
| C3 | complement component 3 | -0.0061246 |
| GPM6B | glycoprotein M6B | -0.00612187 |
| JMJD1C | jumonji domain containing 1C | -0.00611474 |
| GLRX | glutaredoxin (thioltransferase) | -0.00610298 |
| IER5 | immediate early response 5 | -0.00609773 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00609516 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.00609129 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.00609046 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.00608095 |
| EFR3A | EFR3 homolog A (S. cerevisiae) | -0.00606593 |
| STK26 | serine/threonine protein kinase 26 | -0.0060649 |
| LAMA3 | laminin, alpha 3 | -0.00605512 |
| LAMC2 | laminin, gamma 2 | -0.00605504 |
| IL13RA2 | interleukin 13 receptor, alpha 2 | -0.00604341 |
| YIPF3 | Yip1 domain family, member 3 | -0.00603977 |
| AHCYL1 | adenosylhomocysteinase-like 1 | -0.00602195 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00599326 |
| CTSZ | cathepsin Z | -0.00598064 |
| SYNE1 | spectrin repeat containing, nuclear envelope 1 | -0.00597958 |
| SMAD3 | SMAD family member 3 | -0.00597877 |
| ADAMTS5 | ADAM metallopeptidase with thrombospondin type 1 motif, 5 | -0.00597424 |
| TRIB1 | tribbles pseudokinase 1 | -0.00596818 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.00596609 |
| A2M | alpha-2-macroglobulin | -0.00596527 |
| DST | dystonin | -0.00594411 |
| SETBP1 | SET binding protein 1 | -0.00594073 |
| SMC1A | structural maintenance of chromosomes 1A | -0.00593844 |
| RGS5 | regulator of G-protein signaling 5 | -0.00592685 |
| USP24 | ubiquitin specific peptidase 24 | -0.00591697 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00591628 |
| EMX2 | empty spiracles homeobox 2 | -0.00589088 |
| S100A11 | S100 calcium binding protein A11 | -0.00588236 |
| HMOX1 | heme oxygenase 1 | -0.00588222 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.00587605 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.00587417 |
| AGRN | agrin | -0.00587188 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00586916 |
| SCGN | secretagogin, EF-hand calcium binding protein | -0.00584911 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | -0.00584236 |
| TOX | thymocyte selection-associated high mobility group box | -0.0058328 |
| MUC1 | mucin 1, cell surface associated | -0.00583001 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.00582624 |
| MAP9 | microtubule-associated protein 9 | -0.00581064 |
| THBS4 | thrombospondin 4 | -0.00581033 |
| DLD | dihydrolipoamide dehydrogenase | -0.00580911 |
| IL1B | interleukin 1, beta | -0.00580624 |
| LTBR | lymphotoxin beta receptor (TNFR superfamily, member 3) | -0.0058025 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.00579864 |