EIF4E Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description eukaryotic translation initiation factor 4E|The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of cellular mRNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the mRNA. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 1977)
External Link https://ncbi.nlm.nih.gov/gene/1977
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Genes

499 genes differentially expressed following the EIF4E gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0301508
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.0172706
KDM5D lysine (K)-specific demethylase 5D 0.0165779
PCNA proliferating cell nuclear antigen 0.0153536
CHP1 calcineurin-like EF-hand protein 1 0.013697
MEF2C myocyte enhancer factor 2C 0.0135461
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.0123555
CA2 carbonic anhydrase II 0.0117166
SCD5 stearoyl-CoA desaturase 5 0.0116451
ANOS1 anosmin 1 0.0112623
DCXR dicarbonyl/L-xylulose reductase 0.0110482
CSTA cystatin A (stefin A) 0.0102616
OPHN1 oligophrenin 1 0.00996869
LGALS13 lectin, galactoside-binding, soluble, 13 0.00993749
PDE4B phosphodiesterase 4B, cAMP-specific 0.00993478
AK4 adenylate kinase 4 0.00979105
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00971143
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 0.0095594
CYB5A cytochrome b5 type A (microsomal) 0.00947684
POLE3 polymerase (DNA directed), epsilon 3, accessory subunit 0.00947016
TMEM45A transmembrane protein 45A 0.00902875
TCTN2 tectonic family member 2 0.00894997
PIP prolactin-induced protein 0.00885315
PLPBP pyridoxal phosphate binding protein 0.00883627
APMAP adipocyte plasma membrane associated protein 0.00881807
ZNF589 zinc finger protein 589 0.00879231
NRN1 neuritin 1 0.00873654
AQP9 aquaporin 9 0.00865297
OXA1L oxidase (cytochrome c) assembly 1-like 0.00862465
S100A7 S100 calcium binding protein A7 0.00850979
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.0083751
CXADR coxsackie virus and adenovirus receptor 0.00836195
CLC Charcot-Leyden crystal galectin 0.00833194
FABP7 fatty acid binding protein 7, brain 0.00833047
C9 complement component 9 0.00831035
EIF5A eukaryotic translation initiation factor 5A 0.00829029
BID BH3 interacting domain death agonist 0.00824758
STOM stomatin 0.00823706
F12 coagulation factor XII (Hageman factor) 0.0081935
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00816705
FASN fatty acid synthase 0.00796047
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00788424
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.00786437
ARG1 arginase 1 0.00785234
TMSB15A thymosin beta 15a 0.00784816
PSMD10 proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 0.00781426
SELL selectin L 0.0078002
GLTP glycolipid transfer protein 0.00779073
CHPT1 choline phosphotransferase 1 0.00776989
CENPE centromere protein E, 312kDa 0.00771782
SLC25A15 solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 0.00771011
SET SET nuclear proto-oncogene 0.00761324
NPM3 nucleophosmin/nucleoplasmin 3 0.00753276
GPX1 glutathione peroxidase 1 0.00752518
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.00750313
GJA1 gap junction protein, alpha 1, 43kDa 0.00749433
MTARC1 mitochondrial amidoxime reducing component 1 0.00745233
THAP11 THAP domain containing 11 0.00742482
MPO myeloperoxidase 0.0074099
CTSS cathepsin S 0.00740041
PIPOX pipecolic acid oxidase 0.00737461
ADH1C alcohol dehydrogenase 1C (class I), gamma polypeptide 0.00736086
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) 0.00735449
CYTL1 cytokine-like 1 0.00731698
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.00731678
RBM3 RNA binding motif (RNP1, RRM) protein 3 0.00727156
NES nestin 0.00723926
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.00720622
CYP1A2 cytochrome P450, family 1, subfamily A, polypeptide 2 0.0071842
CFHR2 complement factor H-related 2 0.00717345
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.00714669
ADI1 acireductone dioxygenase 1 0.00713322
RMI1 RecQ mediated genome instability 1 0.00712322
CYP4F3 cytochrome P450, family 4, subfamily F, polypeptide 3 0.00712133
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 0.00710944
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 0.00709526
CRP C-reactive protein, pentraxin-related 0.00709371
CD52 CD52 molecule 0.0070599
PBX3 pre-B-cell leukemia homeobox 3 0.00704507
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00697524
DIPK1A divergent protein kinase domain 1A 0.00697413
ADAM19 ADAM metallopeptidase domain 19 0.00694291
HSD17B4 hydroxysteroid (17-beta) dehydrogenase 4 0.00693419
ANXA6 annexin A6 0.00691812
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.00691745
KAT7 K(lysine) acetyltransferase 7 0.00688332
CDC42 cell division cycle 42 0.00688188
FAM234B family with sequence similarity 234 member B 0.00686589
ADORA2B adenosine A2b receptor 0.00681904
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.0067973
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 0.00679271
CPOX coproporphyrinogen oxidase 0.00679256
BIRC5 baculoviral IAP repeat containing 5 0.00678837
CDCA4 cell division cycle associated 4 0.00677662
DNASE1L3 deoxyribonuclease I-like 3 0.0067442
ACAT2 acetyl-CoA acetyltransferase 2 0.00673633
CAV1 caveolin 1, caveolae protein, 22kDa 0.00672746
ZBTB18 zinc finger and BTB domain containing 18 0.00671082
TDP1 tyrosyl-DNA phosphodiesterase 1 0.00669768
UGT2B4 UDP glucuronosyltransferase 2 family, polypeptide B4 0.0066747
RPS9 ribosomal protein S9 0.00665655
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 0.00664559
RPS5 ribosomal protein S5 0.00657824
CREBL2 cAMP responsive element binding protein-like 2 0.00657112
LMNB1 lamin B1 0.00655403
CLDN8 claudin 8 0.00654429
DHFR dihydrofolate reductase 0.00652194
SH3BGRL SH3 domain binding glutamate-rich protein like 0.00649381
CNN2 calponin 2 0.00648588
JCHAIN joining chain of multimeric IgA and IgM 0.00648083
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00646174
PADI2 peptidyl arginine deiminase, type II 0.00644727
MYBPC1 myosin binding protein C, slow type 0.00641518
PRIM1 primase, DNA, polypeptide 1 (49kDa) 0.00639297
RAD23B RAD23 homolog B (S. cerevisiae) 0.00638484
RPA3 replication protein A3, 14kDa 0.00637435
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00637204
FABP1 fatty acid binding protein 1, liver 0.00636513
RAB4A RAB4A, member RAS oncogene family 0.00635626
FBL fibrillarin 0.00634708
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H) 0.00634546
NVL nuclear VCP-like 0.006337
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15 0.00632408
EPB41L4B erythrocyte membrane protein band 4.1 like 4B 0.00627389
CYP2C18 cytochrome P450, family 2, subfamily C, polypeptide 18 0.00625297
GTF3A general transcription factor IIIA 0.00625059
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.00624905
KCTD12 potassium channel tetramerization domain containing 12 0.00623399
TMX1 thioredoxin-related transmembrane protein 1 0.0062339
CRELD2 cysteine-rich with EGF-like domains 2 0.00622442
TTTY15 testis-specific transcript, Y-linked 15 (non-protein coding) 0.00622174
SLC25A6 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 0.00621486
ALCAM activated leukocyte cell adhesion molecule 0.0062107
NRG1 neuregulin 1 0.00618971
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.00618949
FGR FGR proto-oncogene, Src family tyrosine kinase 0.00618017
F2R coagulation factor II (thrombin) receptor 0.00613365
MEFV Mediterranean fever 0.00613027
USP9Y ubiquitin specific peptidase 9, Y-linked 0.00610109
SRPX sushi-repeat containing protein, X-linked 0.00609595
SPCS3 signal peptidase complex subunit 3 homolog (S. cerevisiae) 0.00609484
EMP3 epithelial membrane protein 3 0.00609348
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00609125
SOX11 SRY (sex determining region Y)-box 11 0.00608079
HPX hemopexin 0.00606215
ELK1 ELK1, member of ETS oncogene family 0.00605918
SEPHS1 selenophosphate synthetase 1 0.00603966
PRPS1 phosphoribosyl pyrophosphate synthetase 1 0.00602869
TOR1A torsin family 1, member A (torsin A) 0.00602366
SIVA1 SIVA1, apoptosis-inducing factor 0.00600855
CDK14 cyclin-dependent kinase 14 0.00600213
EIF3I eukaryotic translation initiation factor 3, subunit I 0.00599557
HAL histidine ammonia-lyase 0.00598718
SLC35A5 solute carrier family 35, member A5 0.00598595
TYRP1 tyrosinase-related protein 1 0.00597824
RPL14 ribosomal protein L14 0.00596603
CCDC85B coiled-coil domain containing 85B 0.00596535
MBL2 mannose-binding lectin (protein C) 2, soluble 0.00595369
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2 0.00594826
PCCB propionyl CoA carboxylase, beta polypeptide 0.00594818
MPHOSPH6 M-phase phosphoprotein 6 0.0059225
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6 0.00591164
PRR7 proline rich 7 (synaptic) 0.00591159
DCPS decapping enzyme, scavenger 0.0059065
SAA4 serum amyloid A4, constitutive 0.00587194
METTL7A methyltransferase like 7A 0.0058713
VIPR1 vasoactive intestinal peptide receptor 1 0.00586379
UBE2G2 ubiquitin-conjugating enzyme E2G 2 0.00585865
RPL36 ribosomal protein L36 0.00585645
POU5F1B POU class 5 homeobox 1B 0.00585132
TMEM9B TMEM9 domain family, member B 0.00585061
KCNJ2 potassium channel, inwardly rectifying subfamily J, member 2 0.00584333
TBC1D4 TBC1 domain family, member 4 0.00584195
S100A9 S100 calcium binding protein A9 0.00582939
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 0.00580198
NCAPD2 non-SMC condensin I complex, subunit D2 0.00578934
LIMD1 LIM domains containing 1 0.00578592
FERMT1 fermitin family member 1 0.00578334
SMCO4 single-pass membrane protein with coiled-coil domains 4 0.00578091
SRSF6 serine/arginine-rich splicing factor 6 0.00576553
NANOG Nanog homeobox 0.00575341
FBP1 fructose-1,6-bisphosphatase 1 0.00574248
MAT2B methionine adenosyltransferase II, beta 0.00573998
S100A8 S100 calcium binding protein A8 0.00573088
MSMO1 methylsterol monooxygenase 1 0.00573077
TTN titin 0.00572997
ABHD10 abhydrolase domain containing 10 0.00572542
CLCA2 chloride channel accessory 2 0.00572501
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.00571455
DHDDS dehydrodolichyl diphosphate synthase 0.00571373
SLC17A4 solute carrier family 17, member 4 0.00571336
SLC30A3 solute carrier family 30 (zinc transporter), member 3 0.00570166
RELN reelin 0.00569998
NEIL3 nei endonuclease VIII-like 3 (E. coli) 0.00569778
MYB v-myb avian myeloblastosis viral oncogene homolog 0.00569081
INSIG1 insulin induced gene 1 0.00565931
CBR3 carbonyl reductase 3 0.00565768
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 0.0056566
OSBPL11 oxysterol binding protein-like 11 0.00565636
DUOX1 dual oxidase 1 0.00564769
PIMREG PICALM interacting mitotic regulator 0.00563762
CD27 CD27 molecule 0.00563638
HOPX HOP homeobox 0.00562162
CRIP2 cysteine-rich protein 2 0.00560779
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00559915
EIF4B eukaryotic translation initiation factor 4B 0.005592
LST1 leukocyte specific transcript 1 0.00558419
MRPS27 mitochondrial ribosomal protein S27 0.00558246
TMEM230 transmembrane protein 230 0.00558134
GTPBP3 GTP binding protein 3 (mitochondrial) 0.00557112
SLC38A4 solute carrier family 38, member 4 0.00555857
DDIT4 DNA-damage-inducible transcript 4 0.00554794
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 0.0055343
RNH1 ribonuclease/angiogenin inhibitor 1 0.00552674
CALML3 calmodulin-like 3 0.005523
PPID peptidylprolyl isomerase D 0.0055079
PLIN3 perilipin 3 0.00549149
RNASE2 ribonuclease, RNase A family, 2 (liver, eosinophil-derived neurotoxin) 0.00548865
BHMT betaine--homocysteine S-methyltransferase 0.00547687
LOR loricrin 0.00546184
CD36 CD36 molecule (thrombospondin receptor) 0.00545707
CEP43 centrosomal protein 43 0.00545173
RPS17 ribosomal protein S17 0.00544588
CLEC7A C-type lectin domain family 7, member A 0.00544315
SH3BP4 SH3-domain binding protein 4 0.00543032
PRKY protein kinase, Y-linked, pseudogene 0.00542793
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00541844
HAUS5 HAUS augmin-like complex, subunit 5 0.00541715
CD302 CD302 molecule 0.00541541
GAS1 growth arrest-specific 1 0.00541381
TPM2 tropomyosin 2 (beta) 0.00541026
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00540431
AQP3 aquaporin 3 (Gill blood group) 0.0054031
F3 coagulation factor III (thromboplastin, tissue factor) 0.00538722
BPHL biphenyl hydrolase-like (serine hydrolase) 0.00537015
ANG angiogenin, ribonuclease, RNase A family, 5 0.00536792
HINT1 histidine triad nucleotide binding protein 1 0.00536242
GAL galanin/GMAP prepropeptide 0.00536
TMEM38B transmembrane protein 38B 0.00535438
NINJ1 ninjurin 1 0.00534536
CDC42SE1 CDC42 small effector 1 0.00533301
APCS amyloid P component, serum 0.00531614
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 0.00531478
CFHR4 complement factor H-related 4 0.00531399
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 0.00530151
TAT tyrosine aminotransferase 0.00529946
NQO2 NAD(P)H dehydrogenase, quinone 2 0.00529418
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein) 0.00528634
H2AFV H2A histone family, member V 0.00528045
CARD8 caspase recruitment domain family, member 8 0.00527868

decreased expression

Symbol Name Standardized Value
XIC X chromosome inactivation center -0.0231059
CHGB chromogranin B -0.0164274
PCP4 Purkinje cell protein 4 -0.0158094
SNAP25 synaptosomal-associated protein, 25kDa -0.0147694
HSPA1A heat shock 70kDa protein 1A -0.0142779
SCG5 secretogranin V -0.0142137
KRT19 keratin 19, type I -0.0134978
ATF3 activating transcription factor 3 -0.0132003
GPNMB glycoprotein (transmembrane) nmb -0.0128881
IFI27 interferon, alpha-inducible protein 27 -0.0124466
GRIA2 glutamate receptor, ionotropic, AMPA 2 -0.0123491
AGR2 anterior gradient 2 -0.0121741
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 -0.0113619
CADM1 cell adhesion molecule 1 -0.0113075
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0113012
TFPI2 tissue factor pathway inhibitor 2 -0.0112801
PRAME preferentially expressed antigen in melanoma -0.0110006
PEG10 paternally expressed 10 -0.0108159
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.0105191
AOC1 amine oxidase, copper containing 1 -0.0104605
IGFBP5 insulin-like growth factor binding protein 5 -0.0104292
VEGFA vascular endothelial growth factor A -0.0103881
PLIN2 perilipin 2 -0.0103732
MMP7 matrix metallopeptidase 7 -0.0102529
CFB complement factor B -0.0102423
GARS1 glycyl-tRNA synthetase 1 -0.0101523
ASS1 argininosuccinate synthase 1 -0.0101522
MAPKAPK5 mitogen-activated protein kinase-activated protein kinase 5 -0.0101272
KIF2C kinesin family member 2C -0.0100589
EMP1 epithelial membrane protein 1 -0.0100557
KCNK3 potassium channel, two pore domain subfamily K, member 3 -0.00984926
SYT1 synaptotagmin I -0.0098415
CCN3 cellular communication network factor 3 -0.00983214
WT1 Wilms tumor 1 -0.00975888
RGS16 regulator of G-protein signaling 16 -0.00963584
MFAP5 microfibrillar associated protein 5 -0.00958351
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 -0.00957811
IFI44L interferon-induced protein 44-like -0.00956199
DLK1 delta-like 1 homolog (Drosophila) -0.0094983
CALB1 calbindin 1, 28kDa -0.00948253
PPP1R13B protein phosphatase 1, regulatory subunit 13B -0.00945949
MAGEA3 melanoma antigen family A3 -0.00945637
OSR2 odd-skipped related transciption factor 2 -0.00945559
COL15A1 collagen, type XV, alpha 1 -0.0093769
ALDH1A2 aldehyde dehydrogenase 1 family, member A2 -0.0092937
NCAM1 neural cell adhesion molecule 1 -0.00921112
KRT18 keratin 18, type I -0.0091254
DDIT3 DNA-damage-inducible transcript 3 -0.00903476
SST somatostatin -0.00898842
NRCAM neuronal cell adhesion molecule -0.00898395
BEX1 brain expressed, X-linked 1 -0.00898189
S100P S100 calcium binding protein P -0.00893878
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00887586
MX1 MX dynamin-like GTPase 1 -0.00886028
CUX1 cut-like homeobox 1 -0.00878414
DHRS2 dehydrogenase/reductase (SDR family) member 2 -0.00876984
GAB2 GRB2-associated binding protein 2 -0.00876462
DYNLL1 dynein, light chain, LC8-type 1 -0.00872957
RCAN1 regulator of calcineurin 1 -0.00870744
SEZ6L2 seizure related 6 homolog (mouse)-like 2 -0.00869666
CCNA2 cyclin A2 -0.00868434
EGR1 early growth response 1 -0.00866326
NMNAT2 nicotinamide nucleotide adenylyltransferase 2 -0.00865225
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -0.00862147
GAREM1 GRB2 associated regulator of MAPK1 subtype 1 -0.00860792
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 -0.00859871
UPP1 uridine phosphorylase 1 -0.00848089
PDGFD platelet derived growth factor D -0.00845323
TIMP3 TIMP metallopeptidase inhibitor 3 -0.00842896
TNS3 tensin 3 -0.00832292
MEIS2 Meis homeobox 2 -0.00825304
NEFM neurofilament, medium polypeptide -0.00824305
STC2 stanniocalcin 2 -0.00822349
SPATA20 spermatogenesis associated 20 -0.00821659
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.00819611
MITF microphthalmia-associated transcription factor -0.00817435
BAG3 BCL2-associated athanogene 3 -0.00813106
NFASC neurofascin -0.0081065
REG1A regenerating islet-derived 1 alpha -0.00809069
CPE carboxypeptidase E -0.00808714
FBN2 fibrillin 2 -0.00808663
EPCAM epithelial cell adhesion molecule -0.00807006
MYRF myelin regulatory factor -0.00805397
MINK1 misshapen-like kinase 1 -0.00804364
PAM peptidylglycine alpha-amidating monooxygenase -0.00798988
TFF1 trefoil factor 1 -0.00798749
BRD4 bromodomain containing 4 -0.00796943
MATN2 matrilin 2 -0.00794921
SMAD7 SMAD family member 7 -0.00793297
LCN2 lipocalin 2 -0.00791201
TPBG trophoblast glycoprotein -0.00790902
QPRT quinolinate phosphoribosyltransferase -0.00790687
H1-0 H1.0 linker histone -0.00786611
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00785595
SNAI2 snail family zinc finger 2 -0.00782331
RHOB ras homolog family member B -0.00781903
CNTN1 contactin 1 -0.00774078
PROM1 prominin 1 -0.00771534
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -0.00770471
PTK2 protein tyrosine kinase 2 -0.00763196
RAP1GAP2 RAP1 GTPase activating protein 2 -0.00761463
MEG3 maternally expressed 3 (non-protein coding) -0.00756841
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00756802
PEG3 paternally expressed 3 -0.00754431
HMGN3 high mobility group nucleosomal binding domain 3 -0.00753674
GBAP1 glucosidase, beta, acid pseudogene 1 -0.00746641
TMEM176B transmembrane protein 176B -0.00735597
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.00734178
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) -0.00733747
MSX1 msh homeobox 1 -0.00732823
LMO2 LIM domain only 2 (rhombotin-like 1) -0.00732532
TENM3 teneurin transmembrane protein 3 -0.00727898
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00727435
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -0.00727197
TAC1 tachykinin, precursor 1 -0.0072485
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 -0.00723474
CRISP3 cysteine-rich secretory protein 3 -0.00723035
NDRG1 N-myc downstream regulated 1 -0.00722431
AHNAK2 AHNAK nucleoprotein 2 -0.00718781
HTR2B 5-hydroxytryptamine (serotonin) receptor 2B, G protein-coupled -0.00718751
RASA4 RAS p21 protein activator 4 -0.00718607
AMDHD2 amidohydrolase domain containing 2 -0.00715359
PCSK1 proprotein convertase subtilisin/kexin type 1 -0.00714369
CHGA chromogranin A -0.00708854
USP47 ubiquitin specific peptidase 47 -0.00705073
LAMB1 laminin, beta 1 -0.00704736
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) -0.00704272
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2 -0.00703973
TTC39A tetratricopeptide repeat domain 39A -0.00702889
IFI6 interferon, alpha-inducible protein 6 -0.00701855
QPCT glutaminyl-peptide cyclotransferase -0.00701332
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon -0.00701269
ESR1 estrogen receptor 1 -0.00696596
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.0069656
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 -0.00696422
MGP matrix Gla protein -0.0069566
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00694224
MAGEA12 melanoma antigen family A12 -0.00694205
NBPF10 neuroblastoma breakpoint family, member 10 -0.00691053
HOXC6 homeobox C6 -0.0069072
GEM GTP binding protein overexpressed in skeletal muscle -0.00690529
SV2C synaptic vesicle glycoprotein 2C -0.00688997
INPPL1 inositol polyphosphate phosphatase-like 1 -0.00688659
TIPARP TCDD-inducible poly(ADP-ribose) polymerase -0.00688579
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.00683183
TRPS1 trichorhinophalangeal syndrome I -0.00682825
TAX1BP1 Tax1 (human T-cell leukemia virus type I) binding protein 1 -0.00682754
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.00680533
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00677743
VGLL4 vestigial-like family member 4 -0.00677716
REG3A regenerating islet-derived 3 alpha -0.00676342
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00673577
SPINT1 serine peptidase inhibitor, Kunitz type 1 -0.00671785
ZDHHC11 zinc finger, DHHC-type containing 11 -0.00670853
LPIN1 lipin 1 -0.00670452
SELE selectin E -0.0066882
FGG fibrinogen gamma chain -0.00668451
APOD apolipoprotein D -0.006671
MPRIP myosin phosphatase Rho interacting protein -0.00666595
FKBP9 FK506 binding protein 9, 63 kDa -0.00665222
MUC5B mucin 5B, oligomeric mucus/gel-forming -0.00664948
IFI44 interferon-induced protein 44 -0.00663336
ANK2 ankyrin 2, neuronal -0.00660726
MDK midkine (neurite growth-promoting factor 2) -0.00657361
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.00654346
PPP1R15A protein phosphatase 1, regulatory subunit 15A -0.00653877
SFN stratifin -0.00653502
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00653077
KRT8 keratin 8, type II -0.00650044
GMPR guanosine monophosphate reductase -0.0064728
CEBPB CCAAT/enhancer binding protein (C/EBP), beta -0.00647028
GRK5 G protein-coupled receptor kinase 5 -0.00643651
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00641674
FOLR1 folate receptor 1 (adult) -0.00641481
IFRD1 interferon-related developmental regulator 1 -0.00640221
STC1 stanniocalcin 1 -0.00639189
SEPP1 selenoprotein P, plasma, 1 -0.00636498
CX3CL1 chemokine (C-X3-C motif) ligand 1 -0.00634801
SPEN spen family transcriptional repressor -0.00633675
MGLL monoglyceride lipase -0.00632949
PPM1H protein phosphatase, Mg2+/Mn2+ dependent, 1H -0.0063253
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B -0.00629916
CHD4 chromodomain helicase DNA binding protein 4 -0.00629813
SOBP sine oculis binding protein homolog (Drosophila) -0.00628896
IFI35 interferon-induced protein 35 -0.00628382
ADAM10 ADAM metallopeptidase domain 10 -0.00628336
ABAT 4-aminobutyrate aminotransferase -0.00627519
ZFP36 ZFP36 ring finger protein -0.00626325
TUBA4A tubulin, alpha 4a -0.0062503
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.00624731
KMT5B lysine methyltransferase 5B -0.00624409
CPM carboxypeptidase M -0.00624183
TARS1 threonyl-tRNA synthetase 1 -0.00623311
ISG20 interferon stimulated exonuclease gene 20kDa -0.00622858
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type -0.00621813
MUC16 mucin 16, cell surface associated -0.0061945
GDF15 growth differentiation factor 15 -0.00618588
COL6A2 collagen, type VI, alpha 2 -0.00616565
BTF3P11 basic transcription factor 3 pseudogene 11 -0.00614776
CCNE1 cyclin E1 -0.00613531
DAAM2 dishevelled associated activator of morphogenesis 2 -0.00613501
C3 complement component 3 -0.0061246
GPM6B glycoprotein M6B -0.00612187
JMJD1C jumonji domain containing 1C -0.00611474
GLRX glutaredoxin (thioltransferase) -0.00610298
IER5 immediate early response 5 -0.00609773
TGFBR3 transforming growth factor, beta receptor III -0.00609516
SAMD9 sterile alpha motif domain containing 9 -0.00609129
MAST4 microtubule associated serine/threonine kinase family member 4 -0.00609046
ISG15 ISG15 ubiquitin-like modifier -0.00608095
EFR3A EFR3 homolog A (S. cerevisiae) -0.00606593
STK26 serine/threonine protein kinase 26 -0.0060649
LAMA3 laminin, alpha 3 -0.00605512
LAMC2 laminin, gamma 2 -0.00605504
IL13RA2 interleukin 13 receptor, alpha 2 -0.00604341
YIPF3 Yip1 domain family, member 3 -0.00603977
AHCYL1 adenosylhomocysteinase-like 1 -0.00602195
SLIT2 slit homolog 2 (Drosophila) -0.00599326
CTSZ cathepsin Z -0.00598064
SYNE1 spectrin repeat containing, nuclear envelope 1 -0.00597958
SMAD3 SMAD family member 3 -0.00597877
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.00597424
TRIB1 tribbles pseudokinase 1 -0.00596818
ARID4B AT rich interactive domain 4B (RBP1-like) -0.00596609
A2M alpha-2-macroglobulin -0.00596527
DST dystonin -0.00594411
SETBP1 SET binding protein 1 -0.00594073
SMC1A structural maintenance of chromosomes 1A -0.00593844
RGS5 regulator of G-protein signaling 5 -0.00592685
USP24 ubiquitin specific peptidase 24 -0.00591697
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.00591628
EMX2 empty spiracles homeobox 2 -0.00589088
S100A11 S100 calcium binding protein A11 -0.00588236
HMOX1 heme oxygenase 1 -0.00588222
NR4A1 nuclear receptor subfamily 4, group A, member 1 -0.00587605
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00587417
AGRN agrin -0.00587188
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00586916
SCGN secretagogin, EF-hand calcium binding protein -0.00584911
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F -0.00584236
TOX thymocyte selection-associated high mobility group box -0.0058328
MUC1 mucin 1, cell surface associated -0.00583001
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.00582624
MAP9 microtubule-associated protein 9 -0.00581064
THBS4 thrombospondin 4 -0.00581033
DLD dihydrolipoamide dehydrogenase -0.00580911
IL1B interleukin 1, beta -0.00580624
LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) -0.0058025
ZBTB35 zinc finger and BTB domain containing 35 -0.00579864