EIF4E Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description eukaryotic translation initiation factor 4E|The protein encoded by this gene is a component of the eukaryotic translation initiation factor 4F complex, which recognizes the 7-methylguanosine cap structure at the 5' end of cellular mRNAs. The encoded protein aids in translation initiation by recruiting ribosomes to the mRNA. Association of this protein with the 4F complex is the rate-limiting step in translation initiation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012] (NCBI Entrez Gene Database, 1977)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_EIF4E
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Genes

84 co-expressed genes for EIF4E from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1
ACTL6A actin-like 6A
AFG3L2 AFG3-like AAA ATPase 2
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1
ANKRD17 ankyrin repeat domain 17
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
BAHD1 bromo adjacent homology domain containing 1
BMS1 BMS1 ribosome biogenesis factor
CCNF cyclin F
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CDC7 cell division cycle 7
CDK11A cyclin-dependent kinase 11A
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CLP1 cleavage and polyadenylation factor I subunit 1
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
CPSF4 cleavage and polyadenylation specific factor 4, 30kDa
CSTF3 cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa
CTR9 CTR9, Paf1/RNA polymerase II complex component
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
DDX46 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
DIMT1 DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae)
DLAT dihydrolipoamide S-acetyltransferase
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
EIF4E eukaryotic translation initiation factor 4E
EIF5B eukaryotic translation initiation factor 5B
EXTL2 exostosin-like glycosyltransferase 2
GLMN glomulin, FKBP associated protein
GNL2 guanine nucleotide binding protein-like 2 (nucleolar)
GRB10 growth factor receptor-bound protein 10
GTF2A2 general transcription factor IIA, 2, 12kDa
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
HDAC2 histone deacetylase 2
HMGN4 high mobility group nucleosomal binding domain 4
HNRNPL heterogeneous nuclear ribonucleoprotein L
IDH3A isocitrate dehydrogenase 3 (NAD+) alpha
IFRD2 interferon-related developmental regulator 2
IMMT inner membrane protein, mitochondrial
INTS10 integrator complex subunit 10
KATNA1 katanin p60 (ATPase containing) subunit A 1
KDM3B lysine (K)-specific demethylase 3B
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LARS2 leucyl-tRNA synthetase 2, mitochondrial
MARS methionyl-tRNA synthetase
METAP1 methionyl aminopeptidase 1
MFN2 mitofusin 2
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MZF1 myeloid zinc finger 1
NDUFAF1 NADH dehydrogenase (ubiquinone) complex I, assembly factor 1
NELFA negative elongation factor complex member A
NFRKB nuclear factor related to kappaB binding protein
NKRF NFKB repressing factor
NUDT13 nudix (nucleoside diphosphate linked moiety X)-type motif 13
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
NUP188 nucleoporin 188kDa
NUP62 nucleoporin 62kDa
NUP93 nucleoporin 93kDa
NXT2 nuclear transport factor 2-like export factor 2
PEX3 peroxisomal biogenesis factor 3
PMS1 PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
POLA1 polymerase (DNA directed), alpha 1, catalytic subunit
PSMD3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
PTPN7 protein tyrosine phosphatase, non-receptor type 7
RANBP2 RAN binding protein 2
RAP1A RAP1A, member of RAS oncogene family
RFC1 replication factor C (activator 1) 1, 145kDa
RTCA RNA 3'-terminal phosphate cyclase
RUVBL1 RuvB-like AAA ATPase 1
SEC63 SEC63 homolog (S. cerevisiae)
SFSWAP splicing factor, suppressor of white-apricot family
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SUCLA2 succinate-CoA ligase, ADP-forming, beta subunit
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
THOC2 THO complex 2
TPP2 tripeptidyl peptidase II
TRIM27 tripartite motif containing 27
TTI1 TELO2 interacting protein 1
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)
VARS valyl-tRNA synthetase
XPO6 exportin 6
ZMYM4 zinc finger, MYM-type 4
ZPR1 ZPR1 zinc finger