ELAC2 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description elaC ribonuclease Z 2|The protein encoded by this gene has a C-terminal domain with tRNA 3′ processing endoribonuclease activity, which catalyzes the removal of the 3' trailer from precursor tRNAs. The protein also interacts with activated Smad family member 2 (Smad2) and its nuclear partner forkhead box H1 (also known as FAST-1), and reduced expression can suppress transforming growth factor-beta induced growth arrest. Mutations in this gene result in an increased risk of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009] (NCBI Entrez Gene Database, 60528)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/GNF2_ELAC2
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Genes

46 co-expressed genes for ELAC2 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
BANF1 barrier to autointegration factor 1
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
DDX18 DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
DDX21 DEAD (Asp-Glu-Ala-Asp) box helicase 21
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
DHX15 DEAH (Asp-Glu-Ala-His) box helicase 15
EED embryonic ectoderm development
ELAC2 elaC ribonuclease Z 2
EXOSC8 exosome component 8
FUS FUS RNA binding protein
HDAC1 histone deacetylase 1
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPK heterogeneous nuclear ribonucleoprotein K
HNRNPM heterogeneous nuclear ribonucleoprotein M
HNRNPR heterogeneous nuclear ribonucleoprotein R
HSPB11 heat shock protein family B (small), member 11
KPNB1 karyopherin (importin) beta 1
LAS1L LAS1-like (S. cerevisiae)
NAA15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit
NMT1 N-myristoyltransferase 1
NOP14 NOP14 nucleolar protein
NUP62 nucleoporin 62kDa
PABPN1 poly(A) binding protein, nuclear 1
PDS5A PDS5 cohesin associated factor A
PRPF31 pre-mRNA processing factor 31
PRPF40A PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
RBMX RNA binding motif protein, X-linked
RPA1 replication protein A1, 70kDa
SART3 squamous cell carcinoma antigen recognized by T cells 3
SF3B2 splicing factor 3b, subunit 2, 145kDa
SFPQ splicing factor proline/glutamine-rich
SLC7A5P1 solute carrier family 7 (amino acid transporter light chain, L system), member 5 pseudogene 1
SMARCA5 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
SMC1A structural maintenance of chromosomes 1A
SNRNP200 small nuclear ribonucleoprotein 200kDa (U5)
SRP54 signal recognition particle 54kDa
SRSF1 serine/arginine-rich splicing factor 1
SRSF10 serine/arginine-rich splicing factor 10
TARDBP TAR DNA binding protein
U2SURP U2 snRNP-associated SURP domain containing
ZC3H15 zinc finger CCCH-type containing 15
ZCCHC8 zinc finger, CCHC domain containing 8