ELK1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description ELK1, member of ETS oncogene family|This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum response element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is a nuclear target for the ras-raf-MAPK signaling cascade. This gene produces multiple isoforms by using alternative translational start codons and by alternative splicing. Related pseudogenes have been identified on chromosomes 7 and 14. [provided by RefSeq, Mar 2012] (NCBI Entrez Gene Database, 2002)
External Link http://www.ncbi.nlm.nih.gov/gene/2002
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Genes

55 interacting proteins for ELK1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
APP amyloid beta (A4) precursor protein
BRCA1 breast cancer 1, early onset
CDK6 cyclin-dependent kinase 6
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CREBBP CREB binding protein
EGR1 early growth response 1
ELAVL1 ELAV like RNA binding protein 1
ELK3 ELK3, ETS-domain protein (SRF accessory protein 2)
ELK4 ELK4, ETS-domain protein (SRF accessory protein 1)
EMX1 empty spiracles homeobox 1
EP300 E1A binding protein p300
EWSR1 EWS RNA-binding protein 1
FBXO25 F-box protein 25
FLI1 Fli-1 proto-oncogene, ETS transcription factor
FOS FBJ murine osteosarcoma viral oncogene homolog
GRB10 growth factor receptor-bound protein 10
GRB2 growth factor receptor-bound protein 2
HDAC1 histone deacetylase 1
HOXB13 homeobox B13
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
JUN jun proto-oncogene
KLF4 Kruppel-like factor 4 (gut)
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K3 mitogen-activated protein kinase kinase 3
MAPK1 mitogen-activated protein kinase 1
MAPK10 mitogen-activated protein kinase 10
MAPK11 mitogen-activated protein kinase 11
MAPK12 mitogen-activated protein kinase 12
MAPK13 mitogen-activated protein kinase 13
MAPK14 mitogen-activated protein kinase 14
MAPK15 mitogen-activated protein kinase 15
MAPK3 mitogen-activated protein kinase 3
MAPK6 mitogen-activated protein kinase 6
MAPK7 mitogen-activated protein kinase 7
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MOB4 MOB family member 4, phocein
PADI4 peptidyl arginine deiminase, type IV
PIAS2 protein inhibitor of activated STAT, 2
PRPF4B pre-mRNA processing factor 4B
PSEN1 presenilin 1
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SRF serum response factor (c-fos serum response element-binding transcription factor)
STARD3NL STARD3 N-terminal like
STK16 serine/threonine kinase 16
SUMO1 small ubiquitin-like modifier 1
TAOK2 TAO kinase 2
UBC ubiquitin C
UBE2I ubiquitin-conjugating enzyme E2I