ELK4 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description ELK4, ETS-domain protein (SRF accessory protein 1)|This gene is a member of the Ets family of transcription factors and of the ternary complex factor (TCF) subfamily. Proteins of the TCF subfamily form a ternary complex by binding to the the serum response factor and the serum reponse element in the promoter of the c-fos proto-oncogene. The protein encoded by this gene is phosphorylated by the kinases, MAPK1 and MAPK8. Several transcript variants have been described for this gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2005)
External Link https://ncbi.nlm.nih.gov/gene/2005
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Genes

500 genes differentially expressed following the ELK4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
FABP7 fatty acid binding protein 7, brain 0.0179275
RPS4Y1 ribosomal protein S4, Y-linked 1 0.0147489
S100A7 S100 calcium binding protein A7 0.0142133
COQ8A coenzyme Q8A 0.0137237
EIF1AY eukaryotic translation initiation factor 1A, Y-linked 0.0129511
S100A8 S100 calcium binding protein A8 0.0128703
ASCL1 achaete-scute family bHLH transcription factor 1 0.0124205
CXCL12 chemokine (C-X-C motif) ligand 12 0.0123417
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.0123145
NEBL nebulette 0.0110354
SCGB2A1 secretoglobin, family 2A, member 1 0.0105958
MAP7 microtubule-associated protein 7 0.0102632
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.0099787
FABP4 fatty acid binding protein 4, adipocyte 0.00997028
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00960436
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00952586
CSTA cystatin A (stefin A) 0.00950246
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.00948149
THBS2 thrombospondin 2 0.00906746
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00900804
GTPBP8 GTP-binding protein 8 (putative) 0.00884689
HOPX HOP homeobox 0.00879016
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.008749
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00869231
PEG3 paternally expressed 3 0.00861457
TRIP13 thyroid hormone receptor interactor 13 0.00861406
DPYSL3 dihydropyrimidinase-like 3 0.00857725
PADI2 peptidyl arginine deiminase, type II 0.00847871
KDM5D lysine (K)-specific demethylase 5D 0.00841846
RAB25 RAB25, member RAS oncogene family 0.00836003
CXCL14 chemokine (C-X-C motif) ligand 14 0.00827165
CRABP1 cellular retinoic acid binding protein 1 0.00823022
SDC2 syndecan 2 0.00820725
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.00818934
BEX1 brain expressed, X-linked 1 0.0081634
HBB hemoglobin, beta 0.00816049
CLTB clathrin, light chain B 0.00799029
FAIM Fas apoptotic inhibitory molecule 0.00798619
GUCY2C guanylate cyclase 2C 0.00796654
FCGBP Fc fragment of IgG binding protein 0.00796255
CCT5 chaperonin containing TCP1, subunit 5 (epsilon) 0.00769089
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00761131
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.00758626
PDGFRA platelet-derived growth factor receptor, alpha polypeptide 0.00755188
ACAT2 acetyl-CoA acetyltransferase 2 0.00752607
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.00747926
SLPI secretory leukocyte peptidase inhibitor 0.00747819
SPRR1B small proline-rich protein 1B 0.0074481
NDRG2 NDRG family member 2 0.007426
CALML5 calmodulin-like 5 0.00742401
PDE4B phosphodiesterase 4B, cAMP-specific 0.00741208
GAL galanin/GMAP prepropeptide 0.00739793
GLTP glycolipid transfer protein 0.00735595
PON3 paraoxonase 3 0.0073302
IRF6 interferon regulatory factor 6 0.00726965
MFAP5 microfibrillar associated protein 5 0.00723787
PLN phospholamban 0.00723249
IFRD2 interferon-related developmental regulator 2 0.00722289
S100A9 S100 calcium binding protein A9 0.00721806
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked 0.00721235
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00721107
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.00715185
SPRR1A small proline-rich protein 1A 0.00714839
PLPBP pyridoxal phosphate binding protein 0.00713592
MSMO1 methylsterol monooxygenase 1 0.00712742
PAH phenylalanine hydroxylase 0.00709631
LTF lactotransferrin 0.00707081
LY6D lymphocyte antigen 6 complex, locus D 0.00706655
IL17RB interleukin 17 receptor B 0.00702365
SET SET nuclear proto-oncogene 0.00700688
LEFTY1 left-right determination factor 1 0.00700625
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00698288
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00691725
TYRP1 tyrosinase-related protein 1 0.00686872
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.00686719
SFRP4 secreted frizzled-related protein 4 0.00683425
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 0.00680845
KRT5 keratin 5, type II 0.00674186
ASPN asporin 0.00673201
KLF6 Kruppel-like factor 6 0.00672812
SCGB1D2 secretoglobin, family 1D, member 2 0.00671795
PMP2 peripheral myelin protein 2 0.00669933
PRKD3 protein kinase D3 0.00664475
FBLN5 fibulin 5 0.00661902
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.00661108
CDK14 cyclin-dependent kinase 14 0.00659875
KRT23 keratin 23, type I 0.00657748
PCSK1 proprotein convertase subtilisin/kexin type 1 0.00657673
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.00655872
BIRC5 baculoviral IAP repeat containing 5 0.00654278
COL10A1 collagen, type X, alpha 1 0.00651358
TAGLN transgelin 0.0065092
AK4 adenylate kinase 4 0.00650718
FGFR3 fibroblast growth factor receptor 3 0.00648934
TFCP2L1 transcription factor CP2-like 1 0.00646824
GAS1 growth arrest-specific 1 0.00645836
PODXL podocalyxin-like 0.00645352
CLIC5 chloride intracellular channel 5 0.00642715
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00642431
KLHDC8A kelch domain containing 8A 0.00639076
ESRP1 epithelial splicing regulatory protein 1 0.0063696
CXADR coxsackie virus and adenovirus receptor 0.0063654
TFF3 trefoil factor 3 (intestinal) 0.00636065
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00630395
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial 0.00627804
LGALS13 lectin, galactoside-binding, soluble, 13 0.00627528
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.00624622
ACTA2 actin, alpha 2, smooth muscle, aorta 0.0062396
KRT6B keratin 6B, type II 0.00623772
MRPL39 mitochondrial ribosomal protein L39 0.00622439
WDR7 WD repeat domain 7 0.00621521
KRT19 keratin 19, type I 0.00619922
HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 0.00619623
TFDP1 transcription factor Dp-1 0.00612811
SUMO3 small ubiquitin-like modifier 3 0.00612559
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4 0.00611981
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.00610227
CBFB core-binding factor, beta subunit 0.00608955
FERMT1 fermitin family member 1 0.00608906
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00607638
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.00606607
BTG3 BTG family, member 3 0.00605639
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15 0.00604311
FOLR1 folate receptor 1 (adult) 0.00601698
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.00600235
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0.00600065
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.00597801
DSG3 desmoglein 3 0.00596355
ANXA1 annexin A1 0.00595231
RRM1 ribonucleotide reductase M1 0.00594699
CLDN10 claudin 10 0.00592847
DCN decorin 0.00590921
ILK integrin-linked kinase 0.00590539
KRT6A keratin 6A, type II 0.00589699
NAE1 NEDD8 activating enzyme E1 subunit 1 0.00589497
MT3 metallothionein 3 0.00588953
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 0.00588179
SUSD4 sushi domain containing 4 0.00587912
CDC42 cell division cycle 42 0.00587771
ABHD10 abhydrolase domain containing 10 0.00586714
STEAP3 STEAP family member 3, metalloreductase 0.00585795
PRELP proline/arginine-rich end leucine-rich repeat protein 0.00582344
F3 coagulation factor III (thromboplastin, tissue factor) 0.00582296
KRT15 keratin 15, type I 0.00581716
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0058006
SPRR3 small proline-rich protein 3 0.00578599
PCOLCE2 procollagen C-endopeptidase enhancer 2 0.00577723
CPE carboxypeptidase E 0.00574941
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.00574071
SERBP1 SERPINE1 mRNA binding protein 1 0.00573746
RUVBL1 RuvB-like AAA ATPase 1 0.00572865
LIG1 ligase I, DNA, ATP-dependent 0.005727
ASF1B anti-silencing function 1B histone chaperone 0.00572336
MT1F metallothionein 1F 0.005718
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.0057136
PITX3 paired-like homeodomain 3 0.00567685
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) 0.00566988
DAXX death-domain associated protein 0.0056676
TCN1 transcobalamin I (vitamin B12 binding protein, R binder family) 0.0056596
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00565386
BLNK B-cell linker 0.00562334
CHI3L2 chitinase 3-like 2 0.00562331
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2 0.0056117
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.0055831
PEBP1 phosphatidylethanolamine binding protein 1 0.0055728
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.00557101
SLC43A3 solute carrier family 43, member 3 0.00556666
ANGPT1 angiopoietin 1 0.00555964
MSH2 mutS homolog 2 0.00555633
RGCC regulator of cell cycle 0.00555394
CLCA4 chloride channel accessory 4 0.00555329
AURKB aurora kinase B 0.00554458
NR1D2 nuclear receptor subfamily 1, group D, member 2 0.00554272
MT1H metallothionein 1H 0.00554234
SRPRB signal recognition particle receptor, B subunit 0.00552431
MT1HL1 metallothionein 1H-like 1 0.00552079
CD59 CD59 molecule, complement regulatory protein 0.00550915
LTA4H leukotriene A4 hydrolase 0.00548843
GAP43 growth associated protein 43 0.00548209
GINS2 GINS complex subunit 2 (Psf2 homolog) 0.00546406
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 0.00544947
ANK2 ankyrin 2, neuronal 0.0054235
DOK5 docking protein 5 0.00541955
S100A2 S100 calcium binding protein A2 0.00541698
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme 0.00540987
ALCAM activated leukocyte cell adhesion molecule 0.00540305
EIF5 eukaryotic translation initiation factor 5 0.00539308
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00536732
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00533738
EDN3 endothelin 3 0.0053334
DMAC2L distal membrane arm assembly component 2 like 0.00532646
MEN1 multiple endocrine neoplasia I 0.00532418
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 0.00532184
KARS1 lysyl-tRNA synthetase 1 0.00532076
COX6B1 cytochrome c oxidase subunit VIb polypeptide 1 (ubiquitous) 0.00532033
GALNT6 polypeptide N-acetylgalactosaminyltransferase 6 0.0053047
DLK1 delta-like 1 homolog (Drosophila) 0.00530179
TPM4 tropomyosin 4 0.00529772
FAR2 fatty acyl CoA reductase 2 0.00528818
RBBP4 retinoblastoma binding protein 4 0.00528543
BHLHE41 basic helix-loop-helix family, member e41 0.00527518
WWC1 WW and C2 domain containing 1 0.00526857
SLC19A1 solute carrier family 19 (folate transporter), member 1 0.00526602
MCM2 minichromosome maintenance complex component 2 0.0052517
TLR5 toll-like receptor 5 0.00524085
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C 0.0052273
BBOX1 butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1 0.0052262
CFAP298 cilia and flagella associated protein 298 0.00520725
CA4 carbonic anhydrase IV 0.00520543
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.00518509
PLSCR4 phospholipid scramblase 4 0.00518417
ALDOA aldolase A, fructose-bisphosphate 0.00518311
TMEM176A transmembrane protein 176A 0.00517224
SLC35A5 solute carrier family 35, member A5 0.00515199
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 0.00513934
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae) 0.00513544
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.00513538
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00513471
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2 0.0051233
OLFM1 olfactomedin 1 0.00512192
RNPS1 RNA binding protein S1, serine-rich domain 0.00512182
MLF1 myeloid leukemia factor 1 0.00511175
NFASC neurofascin 0.00510526
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.00509112
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.00508616
PLEKHJ1 pleckstrin homology domain containing, family J member 1 0.00508487
NCAPG2 non-SMC condensin II complex, subunit G2 0.00508473
CEACAM5 carcinoembryonic antigen-related cell adhesion molecule 5 0.00505338
EXPH5 exophilin 5 0.00504945
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 0.00504789
CLDN8 claudin 8 0.00504563
LINC00623 long intergenic non-protein coding RNA 623 0.00503963
PPIF peptidylprolyl isomerase F 0.00503831
SDC1 syndecan 1 0.00503513
LMAN1 lectin, mannose-binding, 1 0.00502994
USP9Y ubiquitin specific peptidase 9, Y-linked 0.00502371
POSTN periostin, osteoblast specific factor 0.00501936
UMOD uromodulin 0.00500669
NPTX2 neuronal pentraxin II 0.00500512
BPI bactericidal/permeability-increasing protein 0.0050023
CCNA2 cyclin A2 0.00499908
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.0049905
TLR4 toll-like receptor 4 0.0049866
BARD1 BRCA1 associated RING domain 1 0.00498392
XPO7 exportin 7 0.00497719
SKAP2 src kinase associated phosphoprotein 2 0.00497625
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.00497541
PI3 peptidase inhibitor 3, skin-derived 0.00496528
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 0.00495879
METTL7A methyltransferase like 7A 0.00495875

decreased expression

Symbol Name Standardized Value
XIC X chromosome inactivation center -0.0134315
PLAAT3 phospholipase A and acyltransferase 3 -0.011263
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.010188
PLK2 polo-like kinase 2 -0.00973125
TGFBI transforming growth factor, beta-induced, 68kDa -0.00966053
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00950095
TFPI2 tissue factor pathway inhibitor 2 -0.00920268
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00912811
NPY neuropeptide Y -0.00901691
BST2 bone marrow stromal cell antigen 2 -0.00891593
COL4A5 collagen, type IV, alpha 5 -0.00862978
CLGN calmegin -0.0085252
LTBP2 latent transforming growth factor beta binding protein 2 -0.00851429
PDGFC platelet derived growth factor C -0.00835047
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.0083501
LOXL2 lysyl oxidase-like 2 -0.00821354
VEGFA vascular endothelial growth factor A -0.00819673
RTN2 reticulon 2 -0.00818593
LEF1 lymphoid enhancer-binding factor 1 -0.00818178
CFB complement factor B -0.00807321
HSPA1A heat shock 70kDa protein 1A -0.00789895
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.00785797
AKR1C3 aldo-keto reductase family 1, member C3 -0.00785014
CCNG2 cyclin G2 -0.00779975
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00765859
ARPP19 cAMP-regulated phosphoprotein, 19kDa -0.00765089
DST dystonin -0.00760879
REG1A regenerating islet-derived 1 alpha -0.00757367
GOLGA8A golgin A8 family, member A -0.00747222
SPON2 spondin 2, extracellular matrix protein -0.00747167
REG3A regenerating islet-derived 3 alpha -0.0074229
FZD2 frizzled class receptor 2 -0.00739946
MAGEB2 melanoma antigen family B2 -0.00736017
ATF5 activating transcription factor 5 -0.0073008
RNF167 ring finger protein 167 -0.0072358
TGM2 transglutaminase 2 -0.00723055
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.00715149
CCNL2 cyclin L2 -0.00714554
PGGHG protein-glucosylgalactosylhydroxylysine glucosidase -0.00714418
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.00707792
C8ORF4 chromosome 8 open reading frame 4 -0.00706265
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00701869
NIBAN1 niban apoptosis regulator 1 -0.00700686
NAV3 neuron navigator 3 -0.00699399
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00698667
CXCL2 chemokine (C-X-C motif) ligand 2 -0.00695005
STK26 serine/threonine protein kinase 26 -0.00687289
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -0.00684311
KLK2 kallikrein-related peptidase 2 -0.00681231
POLR1D polymerase (RNA) I polypeptide D, 16kDa -0.0067488
RRAGA Ras-related GTP binding A -0.00670693
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) -0.00669862
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -0.0066955
SMAD7 SMAD family member 7 -0.0066788
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.00665145
IER5 immediate early response 5 -0.00662595
PAEP progestagen-associated endometrial protein -0.00660518
STC2 stanniocalcin 2 -0.00659509
AKAP8L A kinase (PRKA) anchor protein 8-like -0.00659019
EFNB2 ephrin-B2 -0.00658133
PICALM phosphatidylinositol binding clathrin assembly protein -0.00652374
JMJD6 jumonji domain containing 6 -0.00646802
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -0.00643832
IFI6 interferon, alpha-inducible protein 6 -0.00641484
VPS13B vacuolar protein sorting 13 homolog B (yeast) -0.00636962
HIST1H2AC histone cluster 1, H2ac -0.00636622
MN1 meningioma (disrupted in balanced translocation) 1 -0.00630421
FOXO4 forkhead box O4 -0.00628789
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) -0.00627715
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked -0.00627027
PKD2 polycystic kidney disease 2 (autosomal dominant) -0.00624518
NEFH neurofilament, heavy polypeptide -0.00624269
KDM6A lysine (K)-specific demethylase 6A -0.00623476
ITGAV integrin, alpha V -0.00620376
H1-2 H1.2 linker histone, cluster member -0.00619782
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00619134
NOTCH2NL notch 2 N-terminal like -0.00617937
CPD carboxypeptidase D -0.00615857
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.00612958
PXDC1 PX domain containing 1 -0.00612908
OFD1 oral-facial-digital syndrome 1 -0.00611616
SIRT3 sirtuin 3 -0.00611406
MET MET proto-oncogene, receptor tyrosine kinase -0.00610986
IDO1 indoleamine 2,3-dioxygenase 1 -0.0060881
KAZN kazrin, periplakin interacting protein -0.00608517
PLAT plasminogen activator, tissue -0.00607204
TSPAN15 tetraspanin 15 -0.00606324
MXRA7 matrix-remodelling associated 7 -0.00604476
LAMB1 laminin, beta 1 -0.00604003
CTH cystathionine gamma-lyase -0.00604
FBN2 fibrillin 2 -0.00601817
KLK3 kallikrein-related peptidase 3 -0.00601225
PILRB paired immunoglobin-like type 2 receptor beta -0.00599987
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4 -0.00599189
KANK1 KN motif and ankyrin repeat domains 1 -0.00598755
RNF6 ring finger protein (C3H2C3 type) 6 -0.00598176
PLOD2 procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 -0.00597953
FKBP11 FK506 binding protein 11, 19 kDa -0.00597646
WWC3 WWC family member 3 -0.00596954
MEIS1 Meis homeobox 1 -0.0059576
VCAM1 vascular cell adhesion molecule 1 -0.00595071
HIST1H2BK histone cluster 1, H2bk -0.00591942
SMC1A structural maintenance of chromosomes 1A -0.00590867
PLEC plectin -0.00589842
TKTL1 transketolase-like 1 -0.00589727
TNFAIP2 tumor necrosis factor, alpha-induced protein 2 -0.00588252
C1QB complement component 1, q subcomponent, B chain -0.00587684
ANKRD11 ankyrin repeat domain 11 -0.00586969
ARGLU1 arginine and glutamate rich 1 -0.00581916
OSBPL10 oxysterol binding protein-like 10 -0.00580523
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6 -0.00579488
TNC tenascin C -0.00574136
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 -0.00573668
CHN2 chimerin 2 -0.00572046
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 -0.00571843
MAGEA3 melanoma antigen family A3 -0.00571215
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.0057075
DAAM2 dishevelled associated activator of morphogenesis 2 -0.00569301
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -0.00569193
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.00569015
NBEA neurobeachin -0.00568378
RBPMS RNA binding protein with multiple splicing -0.00567609
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 -0.00567275
AKR1C2 aldo-keto reductase family 1, member C2 -0.00565627
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) -0.00565468
ACACA acetyl-CoA carboxylase alpha -0.00565241
JAM3 junctional adhesion molecule 3 -0.00565112
SSX1 synovial sarcoma, X breakpoint 1 -0.00565056
SPOCK1 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 -0.0056423
ZSWIM8 zinc finger, SWIM-type containing 8 -0.00563146
GPR88 G protein-coupled receptor 88 -0.00562641
NBL1 neuroblastoma 1, DAN family BMP antagonist -0.00559014
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 -0.00558373
TBL1X transducin (beta)-like 1X-linked -0.00557647
PRDX2 peroxiredoxin 2 -0.00557403
HIST1H2BD histone cluster 1, H2bd -0.00557125
MID1 midline 1 -0.00556376
SMTN smoothelin -0.00555613
CXCL11 chemokine (C-X-C motif) ligand 11 -0.00553944
NKX3-1 NK3 homeobox 1 -0.00553899
SACS sacsin molecular chaperone -0.00553689
CCL20 chemokine (C-C motif) ligand 20 -0.00553321
STC1 stanniocalcin 1 -0.00553177
KMT5B lysine methyltransferase 5B -0.00553005
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.00552826
HERC1 HECT and RLD domain containing E3 ubiquitin protein ligase family member 1 -0.00552672
TGFB1I1 transforming growth factor beta 1 induced transcript 1 -0.0055254
TAC1 tachykinin, precursor 1 -0.00552426
NUDT9 nudix (nucleoside diphosphate linked moiety X)-type motif 9 -0.00551102
JARID2 jumonji, AT rich interactive domain 2 -0.00550152
C9 complement component 9 -0.0054983
GRSF1 G-rich RNA sequence binding factor 1 -0.00549754
EML3 echinoderm microtubule associated protein like 3 -0.00547369
RIT1 Ras-like without CAAX 1 -0.00546595
LRP4 low density lipoprotein receptor-related protein 4 -0.00546477
PRPF4B pre-mRNA processing factor 4B -0.00546292
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.00544515
INPPL1 inositol polyphosphate phosphatase-like 1 -0.00544395
FUCA1 fucosidase, alpha-L- 1, tissue -0.00540903
GANAB glucosidase, alpha; neutral AB -0.0053848
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) -0.005384
MPPED2 metallophosphoesterase domain containing 2 -0.00538327
GCLC glutamate-cysteine ligase, catalytic subunit -0.00535415
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 -0.00535257
S100A4 S100 calcium binding protein A4 -0.0053501
PRKCB protein kinase C, beta -0.00534099
CROCCP2 ciliary rootlet coiled-coil, rootletin pseudogene 2 -0.00532783
TPM1 tropomyosin 1 (alpha) -0.00531649
TPST2 tyrosylprotein sulfotransferase 2 -0.00530577
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H') -0.0052995
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.0052978
LAMB2 laminin, beta 2 (laminin S) -0.0052806
MYRF myelin regulatory factor -0.00527708
CSAD cysteine sulfinic acid decarboxylase -0.00527444
NUMA1 nuclear mitotic apparatus protein 1 -0.00527199
PLD3 phospholipase D family, member 3 -0.00526532
LAMA5 laminin, alpha 5 -0.00526354
AKR1C1 aldo-keto reductase family 1, member C1 -0.00526175
REC8 REC8 meiotic recombination protein -0.00525841
PENK proenkephalin -0.00525504
EVC Ellis van Creveld protein -0.00525488
MAGEA12 melanoma antigen family A12 -0.00524848
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G -0.00524791
CDR2L cerebellar degeneration-related protein 2-like -0.00521816
TRRAP transformation/transcription domain-associated protein -0.00520903
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 -0.00520554
WSB1 WD repeat and SOCS box containing 1 -0.00520548
FOLH1B folate hydrolase 1B -0.00520242
ASS1 argininosuccinate synthase 1 -0.00518777
AMOTL2 angiomotin like 2 -0.00518593
MIR22HG MIR22 host gene -0.00517833
WT1 Wilms tumor 1 -0.00517825
SPATA20 spermatogenesis associated 20 -0.00517704
RSRP1 arginine/serine-rich protein 1 -0.00517621
ANKRD10 ankyrin repeat domain 10 -0.00516889
BIK BCL2-interacting killer (apoptosis-inducing) -0.00515187
HMOX1 heme oxygenase 1 -0.00514882
WDR44 WD repeat domain 44 -0.00514582
SPEN spen family transcriptional repressor -0.00512566
IGF2R insulin-like growth factor 2 receptor -0.00511925
TNIK TRAF2 and NCK interacting kinase -0.00511518
FOXF1 forkhead box F1 -0.00510688
ADAM10 ADAM metallopeptidase domain 10 -0.00509485
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) -0.00509212
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha -0.00508383
TCTA T-cell leukemia translocation altered -0.00507472
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2 -0.00505391
UCP2 uncoupling protein 2 (mitochondrial, proton carrier) -0.00505227
WASF1 WAS protein family, member 1 -0.00504174
NPY1R neuropeptide Y receptor Y1 -0.00503916
PRKCZ protein kinase C, zeta -0.00501015
TUG1 taurine up-regulated 1 (non-protein coding) -0.00500867
MYO5C myosin VC -0.00500017
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) -0.00499153
NCOA1 nuclear receptor coactivator 1 -0.00498682
BMI1 BMI1 proto-oncogene, polycomb ring finger -0.00498522
EXOSC4 exosome component 4 -0.00498423
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5 -0.0049772
BASP1 brain abundant, membrane attached signal protein 1 -0.00497533
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -0.00497438
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic -0.00497153
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -0.00496845
ARMCX3 armadillo repeat containing, X-linked 3 -0.00495998
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 -0.00494571
SUN1 Sad1 and UNC84 domain containing 1 -0.00493767
WASL Wiskott-Aldrich syndrome-like -0.0049282
DGKD diacylglycerol kinase, delta 130kDa -0.00492746
EXOC7 exocyst complex component 7 -0.00492434
SCAND1 SCAN domain containing 1 -0.00492384
PPIC peptidylprolyl isomerase C (cyclophilin C) -0.00491703
HIP1R huntingtin interacting protein 1 related -0.0049162
TBC1D16 TBC1 domain family, member 16 -0.00491034
LAMA3 laminin, alpha 3 -0.00489942
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa -0.00489714
ATP13A1 ATPase type 13A1 -0.00489204
GEM GTP binding protein overexpressed in skeletal muscle -0.00488151
CNPY3 canopy FGF signaling regulator 3 -0.00488112
DDIT3 DNA-damage-inducible transcript 3 -0.0048662
TYMP thymidine phosphorylase -0.00486096
DYSF dysferlin -0.00485548
APOD apolipoprotein D -0.00484959
INTS6 integrator complex subunit 6 -0.0048481
TMEM259 transmembrane protein 259 -0.00484277
AGRN agrin -0.00482566
EHBP1L1 EH domain binding protein 1-like 1 -0.00481499
WDR45 WD repeat domain 45 -0.00481487
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00480888
IRF4 interferon regulatory factor 4 -0.00480263
ZFC3H1 zinc finger, C3H1-type containing -0.00479769
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -0.00479225