EMD Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description emerin|Emerin is a serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It mediates membrane anchorage to the cytoskeleton. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2010)
External Link https://ncbi.nlm.nih.gov/gene/2010
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Genes

499 genes differentially expressed following the EMD gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
KRT5 keratin 5, type II 0.0189425
CXCL12 chemokine (C-X-C motif) ligand 12 0.0166985
SFRP1 secreted frizzled-related protein 1 0.0161433
AK4 adenylate kinase 4 0.0161309
CSTA cystatin A (stefin A) 0.0156793
S100A7 S100 calcium binding protein A7 0.0146506
CA2 carbonic anhydrase II 0.014573
DSP desmoplakin 0.0137638
ADM adrenomedullin 0.0135447
ANXA1 annexin A1 0.0135405
KRT6A keratin 6A, type II 0.0134349
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein 0.0128662
MARCKS myristoylated alanine-rich protein kinase C substrate 0.0128277
EIF5A eukaryotic translation initiation factor 5A 0.0123817
GPM6B glycoprotein M6B 0.0122247
IFRD2 interferon-related developmental regulator 2 0.0118692
AQP3 aquaporin 3 (Gill blood group) 0.0117039
DAXX death-domain associated protein 0.0116902
MAL mal, T-cell differentiation protein 0.0116762
FXYD3 FXYD domain containing ion transport regulator 3 0.0116087
CLDN8 claudin 8 0.0115804
NEBL nebulette 0.0115452
PI3 peptidase inhibitor 3, skin-derived 0.0115037
FGFBP1 fibroblast growth factor binding protein 1 0.0112081
SPRR1B small proline-rich protein 1B 0.0111838
PDE4B phosphodiesterase 4B, cAMP-specific 0.0110288
LTF lactotransferrin 0.0109618
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.0108378
CLTB clathrin, light chain B 0.0107954
ANXA3 annexin A3 0.0107565
KRT6B keratin 6B, type II 0.0107167
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.0106964
FAM171A1 family with sequence similarity 171, member A1 0.0106503
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.010576
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 0.0105717
CAMK2N1 calcium/calmodulin-dependent protein kinase II inhibitor 1 0.0105273
MT1HL1 metallothionein 1H-like 1 0.0104997
IL2RG interleukin 2 receptor, gamma 0.0104492
HSPD1 heat shock 60kDa protein 1 (chaperonin) 0.0104359
SELL selectin L 0.0104358
STXBP2 syntaxin binding protein 2 0.0104223
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 0.0100979
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 0.0100317
MT2A metallothionein 2A 0.0100129
CLDN10 claudin 10 0.00999401
MT1H metallothionein 1H 0.00998456
ACTA2 actin, alpha 2, smooth muscle, aorta 0.00997292
PADI2 peptidyl arginine deiminase, type II 0.00995732
GRB7 growth factor receptor-bound protein 7 0.00986392
GYPC glycophorin C (Gerbich blood group) 0.00985972
MSMO1 methylsterol monooxygenase 1 0.00964545
CNN2 calponin 2 0.0096038
KRT14 keratin 14, type I 0.00955507
KRT13 keratin 13, type I 0.00955504
SAT1 spermidine/spermine N1-acetyltransferase 1 0.00954341
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 0.00944036
SLC4A1 solute carrier family 4 (anion exchanger), member 1 (Diego blood group) 0.00940056
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.0093989
SPRR3 small proline-rich protein 3 0.00934071
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 0.00927583
PEG3 paternally expressed 3 0.00916324
NRN1 neuritin 1 0.00914716
HTRA1 HtrA serine peptidase 1 0.00914511
FKBP5 FK506 binding protein 5 0.00913185
BTG3 BTG family, member 3 0.00911257
DHRS3 dehydrogenase/reductase (SDR family) member 3 0.00902204
AOC1 amine oxidase, copper containing 1 0.00901442
SPRR1A small proline-rich protein 1A 0.00901029
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00900679
BAX BCL2-associated X protein 0.00900434
STOM stomatin 0.00896282
MT1G metallothionein 1G 0.00889811
CD59 CD59 molecule, complement regulatory protein 0.00889708
PHLDA1 pleckstrin homology-like domain, family A, member 1 0.00884486
PLPBP pyridoxal phosphate binding protein 0.00883705
MMP9 matrix metallopeptidase 9 0.0088327
GJA1 gap junction protein, alpha 1, 43kDa 0.00881184
IVNS1ABP influenza virus NS1A binding protein 0.00880155
THBS1 thrombospondin 1 0.00879819
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00877689
HACD3 3-hydroxyacyl-CoA dehydratase 3 0.00875904
CRABP1 cellular retinoic acid binding protein 1 0.00875215
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00869992
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.00866211
B4GALT4 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 0.00863887
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00863711
DKK3 dickkopf WNT signaling pathway inhibitor 3 0.00860765
FAM162A family with sequence similarity 162, member A 0.00860332
SKAP2 src kinase associated phosphoprotein 2 0.00860138
MEN1 multiple endocrine neoplasia I 0.00853739
RPL26L1 ribosomal protein L26-like 1 0.00850124
TFCP2L1 transcription factor CP2-like 1 0.00849465
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.00848899
GSTO1 glutathione S-transferase omega 1 0.0084626
UMOD uromodulin 0.00845411
SLPI secretory leukocyte peptidase inhibitor 0.00840709
GPI glucose-6-phosphate isomerase 0.00840106
TARBP1 TAR (HIV-1) RNA binding protein 1 0.00839379
PLGRKT plasminogen receptor, C-terminal lysine transmembrane protein 0.00838549
MMP12 matrix metallopeptidase 12 0.00838321
ALDOA aldolase A, fructose-bisphosphate 0.00836375
CAST calpastatin 0.0083611
TFDP1 transcription factor Dp-1 0.00834642
RGS1 regulator of G-protein signaling 1 0.00833726
TMED9 transmembrane emp24 protein transport domain containing 9 0.00831565
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.00830523
RNF167 ring finger protein 167 0.00829424
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 0.00828817
PITX3 paired-like homeodomain 3 0.00828583
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00826804
CEBPD CCAAT/enhancer binding protein (C/EBP), delta 0.00824868
TRIM29 tripartite motif containing 29 0.00824809
PON2 paraoxonase 2 0.00823856
SLC16A1 solute carrier family 16 (monocarboxylate transporter), member 1 0.00822976
HIGD1A HIG1 hypoxia inducible domain family, member 1A 0.00817824
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.00815194
MOXD1 monooxygenase, DBH-like 1 0.00813101
LCP1 lymphocyte cytosolic protein 1 (L-plastin) 0.00812788
SCNN1A sodium channel, non voltage gated 1 alpha subunit 0.00811844
FABP7 fatty acid binding protein 7, brain 0.00811769
S100A9 S100 calcium binding protein A9 0.00810071
NME4 NME/NM23 nucleoside diphosphate kinase 4 0.00808941
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 0.00807345
AZIN1 antizyme inhibitor 1 0.00806946
VSNL1 visinin-like 1 0.00805543
ME2 malic enzyme 2, NAD(+)-dependent, mitochondrial 0.00802093
SPRED2 sprouty-related, EVH1 domain containing 2 0.00801493
YIPF5 Yip1 domain family, member 5 0.00799725
MT1F metallothionein 1F 0.00797257
MAT2B methionine adenosyltransferase II, beta 0.00795224
GPR171 G protein-coupled receptor 171 0.00794828
LEFTY1 left-right determination factor 1 0.00793972
BCL2A1 BCL2-related protein A1 0.00792523
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00789304
SET SET nuclear proto-oncogene 0.00788263
S100A2 S100 calcium binding protein A2 0.00785787
CMPK1 cytidine monophosphate (UMP-CMP) kinase 1, cytosolic 0.00784382
DAZAP2 DAZ associated protein 2 0.00783971
NUDT21 nudix (nucleoside diphosphate linked moiety X)-type motif 21 0.00782646
TREM1 triggering receptor expressed on myeloid cells 1 0.00781174
TPM4 tropomyosin 4 0.00779681
C7 complement component 7 0.00773089
CRABP2 cellular retinoic acid binding protein 2 0.0077008
CTSS cathepsin S 0.0076771
DSG3 desmoglein 3 0.00766833
FOXG1 forkhead box G1 0.00765808
RSL1D1 ribosomal L1 domain containing 1 0.00765598
MAGT1 magnesium transporter 1 0.00764677
KLK10 kallikrein-related peptidase 10 0.00762429
PDIA3 protein disulfide isomerase family A, member 3 0.00758684
PMP2 peripheral myelin protein 2 0.00754615
IRF6 interferon regulatory factor 6 0.00750445
CDC42 cell division cycle 42 0.00748112
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00748094
RGS4 regulator of G-protein signaling 4 0.00746727
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 0.00743808
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00743357
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.00742039
RPP40 ribonuclease P/MRP 40kDa subunit 0.00740808
MPO myeloperoxidase 0.00740741
OGFOD1 2-oxoglutarate and iron-dependent oxygenase domain containing 1 0.00738337
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.00736316
ALCAM activated leukocyte cell adhesion molecule 0.00736116
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin) 0.0072673
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00724468
KRT81 keratin 81, type II 0.00723976
SIRT3 sirtuin 3 0.00723113
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.00722975
NDC1 NDC1 transmembrane nucleoporin 0.00722519
AREG amphiregulin 0.00722235
COG7 component of oligomeric golgi complex 7 0.00721628
CNTN1 contactin 1 0.00721544
GCA grancalcin, EF-hand calcium binding protein 0.00720576
GIMAP5 GTPase, IMAP family member 5 0.00719208
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.00718566
CRELD2 cysteine-rich with EGF-like domains 2 0.00716904
CRK v-crk avian sarcoma virus CT10 oncogene homolog 0.00715471
NOLC1 nucleolar and coiled-body phosphoprotein 1 0.0071235
MUC5AC mucin 5AC, oligomeric mucus/gel-forming 0.00711768
PEBP1 phosphatidylethanolamine binding protein 1 0.0071073
ETFB electron-transfer-flavoprotein, beta polypeptide 0.00705988
COX5A cytochrome c oxidase subunit Va 0.0070566
TFRC transferrin receptor 0.00703485
MMP8 matrix metallopeptidase 8 0.00703178
LTBP1 latent transforming growth factor beta binding protein 1 0.00701044
GM2A GM2 ganglioside activator 0.00699129
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 0.006972
ADAT1 adenosine deaminase, tRNA-specific 1 0.00696901
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 0.00696058
DCTN4 dynactin 4 (p62) 0.00695702
NUP37 nucleoporin 37kDa 0.00692748
IL10RB interleukin 10 receptor, beta 0.00691744
CCNA2 cyclin A2 0.00691125
ATG5 autophagy related 5 0.00689497
FGF1 fibroblast growth factor 1 (acidic) 0.00689446
RFC5 replication factor C (activator 1) 5, 36.5kDa 0.00688627
MRPL19 mitochondrial ribosomal protein L19 0.00687891
IL1RN interleukin 1 receptor antagonist 0.00687303
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00685599
RAB11FIP1 RAB11 family interacting protein 1 (class I) 0.00685519
C5AR1 complement component 5a receptor 1 0.00684484
NOP16 NOP16 nucleolar protein 0.00683785
PRMT1 protein arginine methyltransferase 1 0.00683579
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 0.00682874
ETHE1 ethylmalonic encephalopathy 1 0.00682482
MT1X metallothionein 1X 0.00682245
DCTPP1 dCTP pyrophosphatase 1 0.00681824
CA12 carbonic anhydrase XII 0.00681619
TOX thymocyte selection-associated high mobility group box 0.00681583
GNG5 guanine nucleotide binding protein (G protein), gamma 5 0.00680342
ATOX1 antioxidant 1 copper chaperone 0.00679969
FCGBP Fc fragment of IgG binding protein 0.00679898
DEFA4 defensin, alpha 4, corticostatin 0.00676028
GLTP glycolipid transfer protein 0.00675447
PRPH peripherin 0.006746
EIF3K eukaryotic translation initiation factor 3, subunit K 0.00672933
ISG20 interferon stimulated exonuclease gene 20kDa 0.00672911
DLST dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex) 0.00672395
ROBO1 roundabout, axon guidance receptor, homolog 1 (Drosophila) 0.00670706
THBS2 thrombospondin 2 0.00668879
LZTS3 leucine zipper, putative tumor suppressor family member 3 0.00668662
RFC2 replication factor C (activator 1) 2, 40kDa 0.00668505
CARHSP1 calcium regulated heat stable protein 1, 24kDa 0.00668218
CTDSPL CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like 0.00666369
LRRN3 leucine rich repeat neuronal 3 0.00665946
ABHD5 abhydrolase domain containing 5 0.00663395
HOMER1 homer scaffolding protein 1 0.00662165
MEIS2 Meis homeobox 2 0.00662046
WASHC4 WASH complex subunit 4 0.00661348
C1QBP complement component 1, q subcomponent binding protein 0.00661143
ALDH5A1 aldehyde dehydrogenase 5 family, member A1 0.00660917
CDCA4 cell division cycle associated 4 0.00659767
MRPL17 mitochondrial ribosomal protein L17 0.00659522
MCL1 myeloid cell leukemia 1 0.0065612
KLF5 Kruppel-like factor 5 (intestinal) 0.0065538
FYB1 FYN binding protein 1 0.00655343
DPH5 diphthamide biosynthesis 5 0.00654066
TP53I3 tumor protein p53 inducible protein 3 0.0065306
CYB5B cytochrome b5 type B (outer mitochondrial membrane) 0.00652957
KLF6 Kruppel-like factor 6 0.00651774
C1ORF54 chromosome 1 open reading frame 54 0.00650385
AP1S1 adaptor-related protein complex 1, sigma 1 subunit 0.00649624
PRKCQ protein kinase C, theta 0.00648943
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.00648774
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa 0.00647773
ASCL1 achaete-scute family bHLH transcription factor 1 0.00646994
NLRP2 NLR family, pyrin domain containing 2 0.00646783
IPO7 importin 7 0.00645616
ATP5PD ATP synthase peripheral stalk subunit d 0.00645239
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.00644398

decreased expression

Symbol Name Standardized Value
PLAAT3 phospholipase A and acyltransferase 3 -0.0203248
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.0152652
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 -0.0145798
SSBP2 single-stranded DNA binding protein 2 -0.0140208
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.0138794
RTN2 reticulon 2 -0.013663
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.0136344
DCLK1 doublecortin-like kinase 1 -0.012873
MAP7 microtubule-associated protein 7 -0.0120745
TPSAB1 tryptase alpha/beta 1 -0.0120594
SPON2 spondin 2, extracellular matrix protein -0.0118306
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) -0.0118227
NOTCH2NL notch 2 N-terminal like -0.0109232
STK26 serine/threonine protein kinase 26 -0.0108093
SMAD7 SMAD family member 7 -0.0107465
PAN2 PAN2 poly(A) specific ribonuclease subunit -0.0107335
HSPB8 heat shock 22kDa protein 8 -0.0106777
DDAH1 dimethylarginine dimethylaminohydrolase 1 -0.0105968
TXLNA taxilin alpha -0.0105471
AKAP8 A kinase (PRKA) anchor protein 8 -0.0105376
ZBTB18 zinc finger and BTB domain containing 18 -0.0104152
ADGRG2 adhesion G protein-coupled receptor G2 -0.010399
RBPMS RNA binding protein with multiple splicing -0.0103724
PHACTR2 phosphatase and actin regulator 2 -0.0103486
NAV3 neuron navigator 3 -0.0102518
MTCL1 microtubule crosslinking factor 1 -0.0100211
ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide -0.00998195
MLPH melanophilin -0.0099377
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00993055
ADGRF5 adhesion G protein-coupled receptor F5 -0.00990428
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00986968
OSR2 odd-skipped related transciption factor 2 -0.00972723
CLU clusterin -0.00970022
ASS1 argininosuccinate synthase 1 -0.00958397
WASL Wiskott-Aldrich syndrome-like -0.00955608
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae) -0.00954283
AMOTL2 angiomotin like 2 -0.00950739
EML3 echinoderm microtubule associated protein like 3 -0.00945682
PMP22 peripheral myelin protein 22 -0.00944173
ACTA1 actin, alpha 1, skeletal muscle -0.00942427
CNPY3 canopy FGF signaling regulator 3 -0.00939975
WDR19 WD repeat domain 19 -0.00924858
CFH complement factor H -0.00924358
GATA6 GATA binding protein 6 -0.00922265
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0092143
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00916353
EFNB2 ephrin-B2 -0.00905539
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1 -0.00899602
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.00898107
ARHGAP29 Rho GTPase activating protein 29 -0.00898042
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -0.00896964
KDM5D lysine (K)-specific demethylase 5D -0.00896484
RGS5 regulator of G-protein signaling 5 -0.00893281
PROCR protein C receptor, endothelial -0.00891453
AKR1C3 aldo-keto reductase family 1, member C3 -0.00891019
ACTC1 actin, alpha, cardiac muscle 1 -0.00888193
DPP4 dipeptidyl-peptidase 4 -0.00883379
AGR2 anterior gradient 2 -0.00880163
KLHL41 kelch-like family member 41 -0.00878949
TSPAN12 tetraspanin 12 -0.00874095
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) -0.00872673
APOD apolipoprotein D -0.00871608
IGFBP1 insulin-like growth factor binding protein 1 -0.0086463
CKM creatine kinase, muscle -0.00860783
GOLGA8A golgin A8 family, member A -0.00858084
SLC4A2 solute carrier family 4 (anion exchanger), member 2 -0.00854917
CDK5RAP3 CDK5 regulatory subunit associated protein 3 -0.00853229
LTBP2 latent transforming growth factor beta binding protein 2 -0.00847644
TENT5A terminal nucleotidyltransferase 5A -0.00845942
TMPRSS4 transmembrane protease, serine 4 -0.00839994
DUSP5 dual specificity phosphatase 5 -0.00837212
FAM117A family with sequence similarity 117, member A -0.00835969
CLGN calmegin -0.00834679
MGP matrix Gla protein -0.00834554
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) -0.00831823
TNNC2 troponin C type 2 (fast) -0.00830854
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.00829348
ING3 inhibitor of growth family, member 3 -0.00822469
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00822055
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.00821696
IFI6 interferon, alpha-inducible protein 6 -0.00819156
ACADVL acyl-CoA dehydrogenase, very long chain -0.00819053
CTSA cathepsin A -0.00812804
KMT5B lysine methyltransferase 5B -0.00811813
MIR22HG MIR22 host gene -0.00811512
LGALS8 lectin, galactoside-binding, soluble, 8 -0.00810841
PTP4A3 protein tyrosine phosphatase type IVA, member 3 -0.00809696
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.00803634
PTP4A2 protein tyrosine phosphatase type IVA, member 2 -0.00803248
LY6E lymphocyte antigen 6 complex, locus E -0.00802237
MMP2 matrix metallopeptidase 2 -0.00799986
MET MET proto-oncogene, receptor tyrosine kinase -0.00799679
AGAP1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 -0.00798775
SYNE3 spectrin repeat containing, nuclear envelope family member 3 -0.00795075
DPYSL2 dihydropyrimidinase-like 2 -0.00794792
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) -0.007936
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -0.00792674
TGM2 transglutaminase 2 -0.0079227
MBL2 mannose-binding lectin (protein C) 2, soluble -0.00791606
EFR3A EFR3 homolog A (S. cerevisiae) -0.00790996
EPS8 epidermal growth factor receptor pathway substrate 8 -0.00787471
GET1 guided entry of tail-anchored proteins factor 1 -0.00785889
ERBB3 erb-b2 receptor tyrosine kinase 3 -0.00784265
KANK2 KN motif and ankyrin repeat domains 2 -0.00780774
RABEP2 rabaptin, RAB GTPase binding effector protein 2 -0.00780704
ITGA7 integrin, alpha 7 -0.00779562
EDRF1 erythroid differentiation regulatory factor 1 -0.00779126
GNG11 guanine nucleotide binding protein (G protein), gamma 11 -0.00779093
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00778412
PLK2 polo-like kinase 2 -0.00775766
CLCN4 chloride channel, voltage-sensitive 4 -0.00775628
TTN titin -0.00774665
PROM1 prominin 1 -0.00773551
STK39 serine threonine kinase 39 -0.00773267
TRIO trio Rho guanine nucleotide exchange factor -0.00769237
CDKN2A cyclin-dependent kinase inhibitor 2A -0.00766968
RSF1 remodeling and spacing factor 1 -0.00766133
MAGEB2 melanoma antigen family B2 -0.00761087
MRPS30 mitochondrial ribosomal protein S30 -0.0075958
IGF2R insulin-like growth factor 2 receptor -0.0075925
GSTT1 glutathione S-transferase theta 1 -0.00757936
RAB8A RAB8A, member RAS oncogene family -0.00756377
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic -0.00755075
CLEC3B C-type lectin domain family 3, member B -0.00754049
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit -0.00753701
SMYD3 SET and MYND domain containing 3 -0.00752738
HMGN3 high mobility group nucleosomal binding domain 3 -0.00752696
G0S2 G0/G1 switch 2 -0.00752023
CFD complement factor D (adipsin) -0.0075163
REG1A regenerating islet-derived 1 alpha -0.00749263
SLC38A1 solute carrier family 38, member 1 -0.00747973
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 -0.00747307
STK25 serine/threonine kinase 25 -0.00747193
GPX3 glutathione peroxidase 3 -0.00745217
ME1 malic enzyme 1, NADP(+)-dependent, cytosolic -0.00742759
SNRNP70 small nuclear ribonucleoprotein 70kDa (U1) -0.00739729
MAGED1 melanoma antigen family D1 -0.00739618
GRB14 growth factor receptor-bound protein 14 -0.00739503
KCNN2 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 -0.00737408
BAD BCL2-associated agonist of cell death -0.00736352
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -0.00733905
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -0.00733372
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00732363
DOCK9 dedicator of cytokinesis 9 -0.00731295
RNF19B ring finger protein 19B -0.00730018
ARGLU1 arginine and glutamate rich 1 -0.00728499
INPP5A inositol polyphosphate-5-phosphatase, 40kDa -0.00728495
DGCR8 DGCR8 microprocessor complex subunit -0.00727643
PDE4DIP phosphodiesterase 4D interacting protein -0.00726768
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0072607
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.00725896
UPF3A UPF3 regulator of nonsense transcripts homolog A (yeast) -0.00725194
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.00724992
NR0B1 nuclear receptor subfamily 0, group B, member 1 -0.00722174
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 -0.00721501
TBX3 T-box 3 -0.0071791
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 -0.00717863
KCTD14 potassium channel tetramerization domain containing 14 -0.00717654
LTBP4 latent transforming growth factor beta binding protein 4 -0.0071754
GLA galactosidase, alpha -0.00717438
TPP2 tripeptidyl peptidase II -0.0071445
RERE arginine-glutamic acid dipeptide (RE) repeats -0.00712685
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) -0.00711679
BTBD3 BTB (POZ) domain containing 3 -0.00708928
DMPK dystrophia myotonica-protein kinase -0.00708723
REG3A regenerating islet-derived 3 alpha -0.00708438
CHRDL1 chordin-like 1 -0.00706143
CXCL5 chemokine (C-X-C motif) ligand 5 -0.00704361
AKAP8L A kinase (PRKA) anchor protein 8-like -0.00702639
HSPA1A heat shock 70kDa protein 1A -0.0070189
KRT19 keratin 19, type I -0.00701518
SIRT1 sirtuin 1 -0.00698044
TCTA T-cell leukemia translocation altered -0.00697896
DES desmin -0.00697715
RPRD2 regulation of nuclear pre-mRNA domain containing 2 -0.00697008
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -0.00695876
IRS1 insulin receptor substrate 1 -0.00695079
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase -0.0069494
ABCB6 ATP-binding cassette, sub-family B (MDR/TAP), member 6 (Langereis blood group) -0.00693169
BAZ2B bromodomain adjacent to zinc finger domain, 2B -0.00692439
ADCY9 adenylate cyclase 9 -0.0069215
CST4 cystatin S -0.00692107
ZDHHC11 zinc finger, DHHC-type containing 11 -0.00692087
HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) -0.00690987
CES1 carboxylesterase 1 -0.00690838
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -0.00687267
HAUS3 HAUS augmin-like complex, subunit 3 -0.00687076
ANAPC2 anaphase promoting complex subunit 2 -0.00684902
DNMT1 DNA (cytosine-5-)-methyltransferase 1 -0.00684152
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.00682122
APMAP adipocyte plasma membrane associated protein -0.00680348
PAXIP1 PAX interacting (with transcription-activation domain) protein 1 -0.00680068
PLA1A phospholipase A1 member A -0.00678943
QPCT glutaminyl-peptide cyclotransferase -0.00675464
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1 -0.00675242
TFF3 trefoil factor 3 (intestinal) -0.0067474
ACSL1 acyl-CoA synthetase long-chain family member 1 -0.00672903
MICAL1 microtubule associated monooxygenase, calponin and LIM domain containing 1 -0.00672822
CDK19 cyclin-dependent kinase 19 -0.00672398
SAFB2 scaffold attachment factor B2 -0.00671861
OTUD3 OTU deubiquitinase 3 -0.00671557
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha -0.00670218
ARID1A AT rich interactive domain 1A (SWI-like) -0.00668161
KLC1 kinesin light chain 1 -0.00668082
TTC39A tetratricopeptide repeat domain 39A -0.00668014
FKBP11 FK506 binding protein 11, 19 kDa -0.00666258
DDX39A DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A -0.00666238
PRKCZ protein kinase C, zeta -0.00662734
NXF3 nuclear RNA export factor 3 -0.00662256
EPB41L2 erythrocyte membrane protein band 4.1-like 2 -0.00660983
CA3 carbonic anhydrase III -0.00659526
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.00659354
PFKM phosphofructokinase, muscle -0.00657512
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1 -0.00654272
PLXND1 plexin D1 -0.00652971
REX1BD required for excision 1-B domain containing -0.00652732
SUN1 Sad1 and UNC84 domain containing 1 -0.00651613
FASN fatty acid synthase -0.00650846
TTC28 tetratricopeptide repeat domain 28 -0.00650569
TOP2B topoisomerase (DNA) II beta 180kDa -0.00649022
TRIM8 tripartite motif containing 8 -0.0064889
CCNL2 cyclin L2 -0.00648046
ZMIZ1 zinc finger, MIZ-type containing 1 -0.00646172
FAM193A family with sequence similarity 193, member A -0.0064517
ANKRD36 ankyrin repeat domain 36 -0.00644557
SMARCC2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2 -0.00644141
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 -0.00641616
U2AF2 U2 small nuclear RNA auxiliary factor 2 -0.00640333
PAEP progestagen-associated endometrial protein -0.00638632
KCNK3 potassium channel, two pore domain subfamily K, member 3 -0.00637645
LUM lumican -0.00636866
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) -0.00636522
EPB41L3 erythrocyte membrane protein band 4.1-like 3 -0.00636301
RSRP1 arginine/serine-rich protein 1 -0.00634941
BCHE butyrylcholinesterase -0.00633384
TBC1D12 TBC1 domain family, member 12 -0.00632875
WWC3 WWC family member 3 -0.00632049
SIDT2 SID1 transmembrane family, member 2 -0.00631214
KIAA0930 KIAA0930 -0.00630221
SH3BP4 SH3-domain binding protein 4 -0.00629708
SUCO SUN domain containing ossification factor -0.00629568
TBL1X transducin (beta)-like 1X-linked -0.00627784
PNISR PNN-interacting serine/arginine-rich protein -0.00627354
IL13RA2 interleukin 13 receptor, alpha 2 -0.00627058
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) -0.00626637
SUGP2 SURP and G patch domain containing 2 -0.00626106
USP48 ubiquitin specific peptidase 48 -0.00626103
MGLL monoglyceride lipase -0.00625693
LPAR2 lysophosphatidic acid receptor 2 -0.00625351