EML4 Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description echinoderm microtubule associated protein like 4|This gene is a member of the echinoderm microtubule associated protein-like family. The encoded WD-repeat protein may be involved in microtubule formation. Abnormal fusion of parts of this gene with portions of the anaplastic lymphoma receptor tyrosine kinase gene, which generates EML4-ALK fusion transcripts, is one of the primary mutations associated with non-small cell lung cancer. Alternative splicing of this gene results in two transcript variants. [provided by RefSeq, Jan 2015] (NCBI Entrez Gene Database, 27436)
External Link https://ncbi.nlm.nih.gov/gene/27436
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Genes

499 genes differentially expressed following the EML4 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.00986697
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha 0.0092844
AKR1C3 aldo-keto reductase family 1, member C3 0.00827381
APOD apolipoprotein D 0.00805637
NIBAN1 niban apoptosis regulator 1 0.00803647
CNPY3 canopy FGF signaling regulator 3 0.00801963
GSTA4 glutathione S-transferase alpha 4 0.00780869
HNMT histamine N-methyltransferase 0.00702647
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 0.00696178
HOPX HOP homeobox 0.00689927
ITM2A integral membrane protein 2A 0.00678683
ECI2 enoyl-CoA delta isomerase 2 0.0067709
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 0.00669467
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor) 0.0065765
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 0.00652488
CNN3 calponin 3, acidic 0.00651461
ABHD4 abhydrolase domain containing 4 0.00637086
TMEM126B transmembrane protein 126B 0.00619319
FASN fatty acid synthase 0.00617027
FSTL1 follistatin-like 1 0.0061385
RAB11FIP2 RAB11 family interacting protein 2 (class I) 0.00606242
ACSL1 acyl-CoA synthetase long-chain family member 1 0.00601978
CCNG2 cyclin G2 0.00599559
NPC2 Niemann-Pick disease, type C2 0.00594153
DLK1 delta-like 1 homolog (Drosophila) 0.00592565
CDO1 cysteine dioxygenase type 1 0.00592311
TRAPPC3 trafficking protein particle complex 3 0.0059093
PDLIM3 PDZ and LIM domain 3 0.00589298
DAPK1 death-associated protein kinase 1 0.00585687
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide 0.00583434
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 0.0057982
MRPL12 mitochondrial ribosomal protein L12 0.00576426
HMG20B high mobility group 20B 0.00572929
C4BPA complement component 4 binding protein, alpha 0.00572505
LAMC1 laminin, gamma 1 (formerly LAMB2) 0.00560093
AKR7A2 aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) 0.00552144
PCLAF PCNA clamp associated factor 0.00549841
RPA3 replication protein A3, 14kDa 0.0053575
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) 0.00535502
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.00534574
AMACR alpha-methylacyl-CoA racemase 0.00534184
MYBPC1 myosin binding protein C, slow type 0.00532898
H1-2 H1.2 linker histone, cluster member 0.00529665
LOXL1 lysyl oxidase-like 1 0.00529074
H1-0 H1.0 linker histone 0.00525175
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 0.00525
BIN1 bridging integrator 1 0.00523754
SPON2 spondin 2, extracellular matrix protein 0.00521898
RPS5 ribosomal protein S5 0.00520886
RTN2 reticulon 2 0.00519364
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00516255
PITX3 paired-like homeodomain 3 0.00514317
AKAP7 A kinase (PRKA) anchor protein 7 0.00513223
ACTC1 actin, alpha, cardiac muscle 1 0.00512872
DHDDS dehydrodolichyl diphosphate synthase 0.0051271
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.00511902
RAMP1 receptor (G protein-coupled) activity modifying protein 1 0.00511648
TMEM14B transmembrane protein 14B 0.00508427
GAS1 growth arrest-specific 1 0.0050833
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 0.00507691
PLIN1 perilipin 1 0.00507571
DPYD dihydropyrimidine dehydrogenase 0.00507338
OGFOD3 2-oxoglutarate and iron-dependent oxygenase domain containing 3 0.00507322
TXNDC9 thioredoxin domain containing 9 0.00507188
SEPTIN10 septin 10 0.00506905
KRT10 keratin 10, type I 0.00506007
ANXA6 annexin A6 0.00504781
BAG2 BCL2-associated athanogene 2 0.00503095
APOA2 apolipoprotein A-II 0.0050307
TIMM8B translocase of inner mitochondrial membrane 8 homolog B (yeast) 0.00502353
FMO5 flavin containing monooxygenase 5 0.00499279
GPX3 glutathione peroxidase 3 0.00498227
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae) 0.00497384
ELOVL5 ELOVL fatty acid elongase 5 0.00494453
EMX2 empty spiracles homeobox 2 0.00492727
ANP32E acidic (leucine-rich) nuclear phosphoprotein 32 family, member E 0.0049044
ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide 0.00486003
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.00485773
APOC2 apolipoprotein C-II 0.00484532
MREG melanoregulin 0.00483452
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) 0.00481943
CPVL carboxypeptidase, vitellogenic-like 0.00481518
MAGEB2 melanoma antigen family B2 0.00479749
CSRP3 cysteine and glycine-rich protein 3 (cardiac LIM protein) 0.00478143
IFI44L interferon-induced protein 44-like 0.00476963
P4HB prolyl 4-hydroxylase, beta polypeptide 0.00475747
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) 0.00475252
NPY neuropeptide Y 0.00472813
RCAN2 regulator of calcineurin 2 0.00472533
NOVA1 neuro-oncological ventral antigen 1 0.00472214
RBX1 ring-box 1, E3 ubiquitin protein ligase 0.00470022
POLR1D polymerase (RNA) I polypeptide D, 16kDa 0.00469323
CP ceruloplasmin (ferroxidase) 0.00468252
IGFBP1 insulin-like growth factor binding protein 1 0.00466218
ACP6 acid phosphatase 6, lysophosphatidic 0.00466115
THYN1 thymocyte nuclear protein 1 0.00465772
FST follistatin 0.00465728
CLU clusterin 0.00465278
SERPIND1 serpin peptidase inhibitor, clade D (heparin cofactor), member 1 0.00463642
MAOB monoamine oxidase B 0.00461231
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) 0.00461101
MICU2 mitochondrial calcium uptake 2 0.00460256
ITGA7 integrin, alpha 7 0.00458639
CAMK1 calcium/calmodulin-dependent protein kinase I 0.00458607
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) 0.00456823
AMH anti-Mullerian hormone 0.00455743
PRDX4 peroxiredoxin 4 0.00454531
ADIPOQ adiponectin, C1Q and collagen domain containing 0.00453782
COL4A5 collagen, type IV, alpha 5 0.00450281
CCDC86 coiled-coil domain containing 86 0.00449801
ATP5MG ATP synthase membrane subunit g 0.00449725
CYB5A cytochrome b5 type A (microsomal) 0.00446955
ACTA1 actin, alpha 1, skeletal muscle 0.00443489
HIST1H2BK histone cluster 1, H2bk 0.00440531
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9 0.00439557
PLAAT3 phospholipase A and acyltransferase 3 0.00439466
CD48 CD48 molecule 0.00439197
PROM1 prominin 1 0.00437654
RXRA retinoid X receptor, alpha 0.00437242
CTSH cathepsin H 0.00437077
PRKCB protein kinase C, beta 0.00436562
ACSL5 acyl-CoA synthetase long-chain family member 5 0.00435585
RBPMS RNA binding protein with multiple splicing 0.00435112
ZNF518A zinc finger protein 518A 0.00435012
SGMS1 sphingomyelin synthase 1 0.00434761
IL13RA2 interleukin 13 receptor, alpha 2 0.00434592
C3 complement component 3 0.00434572
CDK14 cyclin-dependent kinase 14 0.00432104
LAMP2 lysosomal-associated membrane protein 2 0.00432081
PPL periplakin 0.00432037
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) 0.00432032
CD99 CD99 molecule 0.00431196
PPAP2A phosphatidic acid phosphatase type 2A 0.00424694
CRYL1 crystallin, lambda 1 0.00424061
FAM8A1 family with sequence similarity 8, member A1 0.00423926
LYN LYN proto-oncogene, Src family tyrosine kinase 0.0042364
HPF1 histone PARylation factor 1 0.00423526
MMP7 matrix metallopeptidase 7 0.00423277
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 0.00423173
ZBTB20 zinc finger and BTB domain containing 20 0.00421806
AGTR1 angiotensin II receptor, type 1 0.00419506
HSDL2 hydroxysteroid dehydrogenase like 2 0.00417803
EFNB2 ephrin-B2 0.004178
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) 0.0041705
AHSG alpha-2-HS-glycoprotein 0.0041651
KRT1 keratin 1, type II 0.00414702
KIAA0125 KIAA0125 0.00414059
CXCL14 chemokine (C-X-C motif) ligand 14 0.00413233
ACOT9 acyl-CoA thioesterase 9 0.00413196
EPAS1 endothelial PAS domain protein 1 0.00411789
PER3 period circadian clock 3 0.00410559
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa 0.00410336
UBR7 ubiquitin protein ligase E3 component n-recognin 7 (putative) 0.00410264
MGST2 microsomal glutathione S-transferase 2 0.00410072
GOLPH3L golgi phosphoprotein 3-like 0.00410004
SLC2A4RG SLC2A4 regulator 0.00409373
EPHX3 epoxide hydrolase 3 0.00408892
BAD BCL2-associated agonist of cell death 0.0040873
TNC tenascin C 0.00408701
ERBB3 erb-b2 receptor tyrosine kinase 3 0.0040805
IPO5 importin 5 0.00407555
NDUFB1 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 1, 7kDa 0.00407554
MGST3 microsomal glutathione S-transferase 3 0.00406582
ARMCX6 armadillo repeat containing, X-linked 6 0.00406226
SLC27A5 solute carrier family 27 (fatty acid transporter), member 5 0.00404854
H2AX H2A.X variant histone 0.00404294
AKR1C1 aldo-keto reductase family 1, member C1 0.00403962
AK4 adenylate kinase 4 0.00402894
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.00402222
IQGAP2 IQ motif containing GTPase activating protein 2 0.00399132
MTMR11 myotubularin related protein 11 0.00398202
TTR transthyretin 0.00397594
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 0.00397462
TTC38 tetratricopeptide repeat domain 38 0.0039702
RUFY3 RUN and FYVE domain containing 3 0.0039677
ABHD2 abhydrolase domain containing 2 0.00396005
MEX3D mex-3 RNA binding family member D 0.00394951
SVIL supervillin 0.00394298
PHACTR2 phosphatase and actin regulator 2 0.00394162
C6 complement component 6 0.00393459
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.00391899
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1 0.00390895
SFN stratifin 0.00388809
HAUS4 HAUS augmin-like complex, subunit 4 0.00388721
ALDH9A1 aldehyde dehydrogenase 9 family, member A1 0.0038853
COLEC12 collectin sub-family member 12 0.00387842
MSRB1 methionine sulfoxide reductase B1 0.003871
CST7 cystatin F (leukocystatin) 0.00386588
APLP2 amyloid beta (A4) precursor-like protein 2 0.00386468
NQO2 NAD(P)H dehydrogenase, quinone 2 0.00386458
ZNF106 zinc finger protein 106 0.00385516
NUSAP1 nucleolar and spindle associated protein 1 0.00384817
UBL3 ubiquitin-like 3 0.00384622
PKIA protein kinase (cAMP-dependent, catalytic) inhibitor alpha 0.0038452
RPA2 replication protein A2, 32kDa 0.0038439
C1ORF174 chromosome 1 open reading frame 174 0.00382436
IGSF6 immunoglobulin superfamily, member 6 0.00382404
P4HTM prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum) 0.0038233
CD2 CD2 molecule 0.00382246
MTARC1 mitochondrial amidoxime reducing component 1 0.00381759
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.00381672
CETN2 centrin, EF-hand protein, 2 0.00381372
RERE arginine-glutamic acid dipeptide (RE) repeats 0.00380476
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.00380353
RGN regucalcin 0.00380197
COMMD8 COMM domain containing 8 0.00379729
GNG12 guanine nucleotide binding protein (G protein), gamma 12 0.00378674
RPL36 ribosomal protein L36 0.00378465
RTN3 reticulon 3 0.00377605
YBX3 Y box binding protein 3 0.00375786
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 0.00375765
KANK2 KN motif and ankyrin repeat domains 2 0.00375677
CHN2 chimerin 2 0.00375655
EZH2 enhancer of zeste 2 polycomb repressive complex 2 subunit 0.00373466
VTCN1 V-set domain containing T cell activation inhibitor 1 0.00372689
USP32P2 ubiquitin specific peptidase 32 pseudogene 2 0.00370611
KAZN kazrin, periplakin interacting protein 0.00369885
RP2 retinitis pigmentosa 2 (X-linked recessive) 0.00369547
CCDC85B coiled-coil domain containing 85B 0.00369526
GPX4 glutathione peroxidase 4 0.00369511
CUL4B cullin 4B 0.00368528
SCD stearoyl-CoA desaturase (delta-9-desaturase) 0.00368133
SEC23A Sec23 homolog A (S. cerevisiae) 0.00368104
TRIP6 thyroid hormone receptor interactor 6 0.00367364
PCOLCE2 procollagen C-endopeptidase enhancer 2 0.00366146
PTP4A3 protein tyrosine phosphatase type IVA, member 3 0.00365936
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.00365849
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.0036509
GNG10 guanine nucleotide binding protein (G protein), gamma 10 0.00363401
EPHA4 EPH receptor A4 0.00362879
DESI1 desumoylating isopeptidase 1 0.00362873
CD58 CD58 molecule 0.00362776
ADAM10 ADAM metallopeptidase domain 10 0.00362459
IFI44 interferon-induced protein 44 0.00362418
SLCO1B3 solute carrier organic anion transporter family, member 1B3 0.00362248
JPT1 Jupiter microtubule associated homolog 1 0.00362198
TUBB6 tubulin, beta 6 class V 0.00361832
TGFBR3 transforming growth factor, beta receptor III 0.00361736
UNG uracil-DNA glycosylase 0.00361673
PDGFC platelet derived growth factor C 0.00361494
NMT2 N-myristoyltransferase 2 0.00360818
PTP4A2 protein tyrosine phosphatase type IVA, member 2 0.00360251
CEP57 centrosomal protein 57kDa 0.00359947
LACTB2 lactamase, beta 2 0.00358898
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 0.00358762
SORBS2 sorbin and SH3 domain containing 2 0.00357878
NCK1 NCK adaptor protein 1 0.00357608
GNMT glycine N-methyltransferase 0.00357325
LIPC lipase, hepatic 0.00356551
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase 0.00356245

decreased expression

Symbol Name Standardized Value
TFRC transferrin receptor -0.00908804
CA2 carbonic anhydrase II -0.00837009
HSPA1A heat shock 70kDa protein 1A -0.00836882
MAGEA3 melanoma antigen family A3 -0.00833549
POSTN periostin, osteoblast specific factor -0.0083063
SCNN1A sodium channel, non voltage gated 1 alpha subunit -0.00818241
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 -0.00777553
ZNF395 zinc finger protein 395 -0.00771175
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.00756923
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein -0.00737645
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -0.00728453
ISG20 interferon stimulated exonuclease gene 20kDa -0.00719356
EZR ezrin -0.00710925
PFKFB3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 -0.00706855
S100A8 S100 calcium binding protein A8 -0.00702966
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00698361
XPO7 exportin 7 -0.00694776
AREG amphiregulin -0.0068891
LAMP3 lysosomal-associated membrane protein 3 -0.00680652
KRT18 keratin 18, type I -0.00677672
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -0.00668818
AUTS2 autism susceptibility candidate 2 -0.00654923
ALCAM activated leukocyte cell adhesion molecule -0.00653631
APOLD1 apolipoprotein L domain containing 1 -0.00648211
SLC38A1 solute carrier family 38, member 1 -0.00643828
DAXX death-domain associated protein -0.00642934
SGCE sarcoglycan, epsilon -0.0063931
CIAPIN1 cytokine induced apoptosis inhibitor 1 -0.00638003
GRB7 growth factor receptor-bound protein 7 -0.00636738
ASCL1 achaete-scute family bHLH transcription factor 1 -0.0063669
TFF1 trefoil factor 1 -0.00633226
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 -0.00622438
KLK10 kallikrein-related peptidase 10 -0.00618932
INHBA inhibin, beta A -0.00618697
MT1F metallothionein 1F -0.00617828
EIF5 eukaryotic translation initiation factor 5 -0.00616051
CXCR4 chemokine (C-X-C motif) receptor 4 -0.00613025
ZNF586 zinc finger protein 586 -0.00604503
PPIF peptidylprolyl isomerase F -0.006005
EPCAM epithelial cell adhesion molecule -0.00599315
PHLDA1 pleckstrin homology-like domain, family A, member 1 -0.00595958
UBFD1 ubiquitin family domain containing 1 -0.00591128
S100P S100 calcium binding protein P -0.00588343
EIF5A eukaryotic translation initiation factor 5A -0.0058822
ODC1 ornithine decarboxylase 1 -0.00586319
CALB1 calbindin 1, 28kDa -0.00585286
ACKR3 atypical chemokine receptor 3 -0.00582486
HPCAL1 hippocalcin-like 1 -0.00573197
THBS2 thrombospondin 2 -0.00571032
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00570363
CPT1A carnitine palmitoyltransferase 1A (liver) -0.0057026
MT1H metallothionein 1H -0.00567466
ITPKB inositol-trisphosphate 3-kinase B -0.00566814
MT1HL1 metallothionein 1H-like 1 -0.00566613
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.00565163
CARMIL1 capping protein regulator and myosin 1 linker 1 -0.00564174
DDIT3 DNA-damage-inducible transcript 3 -0.00563573
MT2A metallothionein 2A -0.00563262
GPR137B G protein-coupled receptor 137B -0.00561931
SIK1 salt-inducible kinase 1 -0.00554864
MSMB microseminoprotein, beta- -0.00554838
AGR2 anterior gradient 2 -0.00553446
PLLP plasmolipin -0.00552983
RGCC regulator of cell cycle -0.00552343
MAP1LC3B microtubule-associated protein 1 light chain 3 beta -0.00544067
STXBP2 syntaxin binding protein 2 -0.00542975
CPE carboxypeptidase E -0.00539434
PFKP phosphofructokinase, platelet -0.00538904
NEBL nebulette -0.00534769
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -0.00532423
SST somatostatin -0.00531639
MT1X metallothionein 1X -0.00530918
MT1G metallothionein 1G -0.00526707
ANO1 anoctamin 1, calcium activated chloride channel -0.0052505
TCP1 t-complex 1 -0.00522401
ADIRF adipogenesis regulatory factor -0.00521695
MFAP3L microfibrillar-associated protein 3-like -0.00521528
CAST calpastatin -0.00520384
AUP1 ancient ubiquitous protein 1 -0.00519792
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -0.00519771
TFPI2 tissue factor pathway inhibitor 2 -0.00519466
PBK PDZ binding kinase -0.00519276
WARS1 tryptophanyl-tRNA synthetase 1 -0.00517049
SPOCK2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 -0.00509286
THBD thrombomodulin -0.00509038
ATP6V0B ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b -0.00508989
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00505092
STK10 serine/threonine kinase 10 -0.00504126
MMP12 matrix metallopeptidase 12 -0.00503388
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 -0.00502864
RFC5 replication factor C (activator 1) 5, 36.5kDa -0.00502276
MUC2 mucin 2, oligomeric mucus/gel-forming -0.00502204
ARPP19 cAMP-regulated phosphoprotein, 19kDa -0.00496363
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 -0.00494931
IFI27 interferon, alpha-inducible protein 27 -0.00493471
PDE4B phosphodiesterase 4B, cAMP-specific -0.00492017
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -0.00491781
COTL1 coactosin-like F-actin binding protein 1 -0.00490772
LXN latexin -0.00490388
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.00489201
KPNA4 karyopherin alpha 4 (importin alpha 3) -0.00489095
BLNK B-cell linker -0.00488213
KCNJ16 potassium channel, inwardly rectifying subfamily J, member 16 -0.00487918
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 -0.00487529
MYO5A myosin VA (heavy chain 12, myoxin) -0.00487263
PCDH9 protocadherin 9 -0.0048717
HOMER1 homer scaffolding protein 1 -0.00485414
GSTZ1 glutathione S-transferase zeta 1 -0.00485057
GREM1 gremlin 1, DAN family BMP antagonist -0.00482836
TOR1A torsin family 1, member A (torsin A) -0.00482018
MTUS1 microtubule associated tumor suppressor 1 -0.004819
ELF4 E74-like factor 4 (ets domain transcription factor) -0.00478108
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 -0.00477376
NR2F1 nuclear receptor subfamily 2, group F, member 1 -0.00474522
TREM1 triggering receptor expressed on myeloid cells 1 -0.00474333
CRABP1 cellular retinoic acid binding protein 1 -0.00473935
BID BH3 interacting domain death agonist -0.004737
SLC25A46 solute carrier family 25, member 46 -0.00472837
ERAP1 endoplasmic reticulum aminopeptidase 1 -0.00471656
HCRT hypocretin (orexin) neuropeptide precursor -0.00470037
HSPH1 heat shock 105kDa/110kDa protein 1 -0.00467527
MB myoglobin -0.0046691
MT1M metallothionein 1M -0.00464359
CARD10 caspase recruitment domain family, member 10 -0.00462046
ITGA6 integrin, alpha 6 -0.0045938
BCL3 B-cell CLL/lymphoma 3 -0.00457605
KRT8 keratin 8, type II -0.00454932
FGFR2 fibroblast growth factor receptor 2 -0.00454203
KIF5C kinesin family member 5C -0.00452569
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 -0.00452523
TENT4A terminal nucleotidyltransferase 4A -0.00451769
ACP1 acid phosphatase 1, soluble -0.00446885
NRG1 neuregulin 1 -0.00445551
ELF1 E74-like factor 1 (ets domain transcription factor) -0.00445456
GADD45A growth arrest and DNA-damage-inducible, alpha -0.004441
MMP1 matrix metallopeptidase 1 -0.0044284
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa -0.004416
HMGA1 high mobility group AT-hook 1 -0.00441075
SRGN serglycin -0.00440034
KRT81 keratin 81, type II -0.00439646
C3ORF52 chromosome 3 open reading frame 52 -0.00439363
PIGP phosphatidylinositol glycan anchor biosynthesis, class P -0.00437674
LARP1 La ribonucleoprotein domain family, member 1 -0.00437433
SDC4 syndecan 4 -0.00437112
TRIP13 thyroid hormone receptor interactor 13 -0.00436443
GNA13 guanine nucleotide binding protein (G protein), alpha 13 -0.00435552
FXYD3 FXYD domain containing ion transport regulator 3 -0.00435002
C5AR1 complement component 5a receptor 1 -0.00434941
SPINT2 serine peptidase inhibitor, Kunitz type, 2 -0.00433325
SLC31A2 solute carrier family 31 (copper transporter), member 2 -0.00433078
GPI glucose-6-phosphate isomerase -0.00432921
MRPL18 mitochondrial ribosomal protein L18 -0.00432429
ZBED2 zinc finger, BED-type containing 2 -0.00432348
AP2B1 adaptor-related protein complex 2, beta 1 subunit -0.00431054
STC1 stanniocalcin 1 -0.00430012
CNTN1 contactin 1 -0.00427297
DIPK1A divergent protein kinase domain 1A -0.00426917
VWF von Willebrand factor -0.00425902
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP) -0.00425271
ZNF331 zinc finger protein 331 -0.00425024
KRT19 keratin 19, type I -0.00423463
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2 -0.00421412
TPD52 tumor protein D52 -0.00421021
CX3CL1 chemokine (C-X3-C motif) ligand 1 -0.00420775
TFF3 trefoil factor 3 (intestinal) -0.00418773
KCMF1 potassium channel modulatory factor 1 -0.00418252
LEFTY1 left-right determination factor 1 -0.00417811
PCDH17 protocadherin 17 -0.00417772
ZNF165 zinc finger protein 165 -0.00417458
FZD3 frizzled class receptor 3 -0.00417224
JCAD junctional cadherin 5 associated -0.00415991
MCL1 myeloid cell leukemia 1 -0.0041444
HSPA6 heat shock 70kDa protein 6 (HSP70B') -0.0041434
PLP2 proteolipid protein 2 (colonic epithelium-enriched) -0.00413068
SEC14L1 SEC14-like 1 (S. cerevisiae) -0.00412536
CHST15 carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 -0.00412234
SELE selectin E -0.00411092
DDRGK1 DDRGK domain containing 1 -0.00411031
SARAF store-operated calcium entry-associated regulatory factor -0.00410877
PTHLH parathyroid hormone-like hormone -0.00410257
AP1G1 adaptor-related protein complex 1, gamma 1 subunit -0.004089
KRT14 keratin 14, type I -0.00407616
KRT7 keratin 7, type II -0.00407591
BTG2 BTG family, member 2 -0.00407293
FKBP4 FK506 binding protein 4, 59kDa -0.00407237
ASNS asparagine synthetase (glutamine-hydrolyzing) -0.00406857
PBX3 pre-B-cell leukemia homeobox 3 -0.0040653
HK2 hexokinase 2 -0.00405654
IFI16 interferon, gamma-inducible protein 16 -0.00405595
CBFB core-binding factor, beta subunit -0.00405211
CDH5 cadherin 5, type 2 (vascular endothelium) -0.00405043
PHF10 PHD finger protein 10 -0.00405021
PLXNA1 plexin A1 -0.0040479
C21ORF91 chromosome 21 open reading frame 91 -0.00404151
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 -0.00403502
ANXA1 annexin A1 -0.00403381
KLF5 Kruppel-like factor 5 (intestinal) -0.00402619
WWC1 WW and C2 domain containing 1 -0.00402566
TGIF2 TGFB-induced factor homeobox 2 -0.00402449
PLCB4 phospholipase C, beta 4 -0.00401874
LPXN leupaxin -0.00401855
KIAA0040 KIAA0040 -0.00401209
PLPBP pyridoxal phosphate binding protein -0.00401155
MAL mal, T-cell differentiation protein -0.00399368
PRNP prion protein -0.00399003
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial -0.00398522
DNM1L dynamin 1-like -0.00397822
ACP5 acid phosphatase 5, tartrate resistant -0.00397637
NOLC1 nucleolar and coiled-body phosphoprotein 1 -0.00396584
MMP9 matrix metallopeptidase 9 -0.00396286
MFSD1 major facilitator superfamily domain containing 1 -0.00395958
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1 -0.00395163
GOLGA8A golgin A8 family, member A -0.00395154
CTTN cortactin -0.0039511
C2CD2 C2 calcium-dependent domain containing 2 -0.00394943
MUC16 mucin 16, cell surface associated -0.00394656
AHNAK2 AHNAK nucleoprotein 2 -0.00393995
SLC12A1 solute carrier family 12 (sodium/potassium/chloride transporter), member 1 -0.00393995
SEC62 SEC62 homolog (S. cerevisiae) -0.0039393
ACAT2 acetyl-CoA acetyltransferase 2 -0.00393093
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 -0.00392154
DACT1 dishevelled-binding antagonist of beta-catenin 1 -0.00391824
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 -0.00391496
SGK1 serum/glucocorticoid regulated kinase 1 -0.00391053
SELENBP1 selenium binding protein 1 -0.00390996
TRIM22 tripartite motif containing 22 -0.00390849
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) -0.00390748
CALCA calcitonin-related polypeptide alpha -0.00390748
MARCHF6 membrane associated ring-CH-type finger 6 -0.00389763
KLF6 Kruppel-like factor 6 -0.00389307
FCHSD2 FCH and double SH3 domains 2 -0.00388294
HSPD1 heat shock 60kDa protein 1 (chaperonin) -0.00387122
TSPAN1 tetraspanin 1 -0.00386833
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.0038623
PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma -0.00385754
CCT2 chaperonin containing TCP1, subunit 2 (beta) -0.0038572
SH3GL2 SH3-domain GRB2-like 2 -0.00385712
HSPA4 heat shock 70kDa protein 4 -0.00384952
PLAU plasminogen activator, urokinase -0.00384773
DAZAP2 DAZ associated protein 2 -0.00384097
OSBPL10 oxysterol binding protein-like 10 -0.00380692
SAMD9 sterile alpha motif domain containing 9 -0.00380558
ERP44 endoplasmic reticulum protein 44 -0.00380457
RRAD Ras-related associated with diabetes -0.00379863
NANS N-acetylneuraminic acid synthase -0.00379244
ARG2 arginase 2 -0.00378703
CCK cholecystokinin -0.00378599
IRF1 interferon regulatory factor 1 -0.00378401
SPR sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) -0.00378122