ENG Gene Set

Dataset Hub Proteins Protein-Protein Interactions
Category physical interactions
Type hub protein
Description endoglin|This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013] (NCBI Entrez Gene Database, 2022)
External Link http://www.ncbi.nlm.nih.gov/gene/2022
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Genes

78 interacting proteins for hub protein ENG from the curated Hub Proteins Protein-Protein Interactions dataset.

Symbol Name
ABCC8 ATP-binding cassette, sub-family C (CFTR/MRP), member 8
ACTL6A actin-like 6A
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AGPAT9 1-acylglycerol-3-phosphate O-acyltransferase 9
APOBEC3G apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
AQP9 aquaporin 9
ARFIP2 ADP-ribosylation factor interacting protein 2
AZF1 azoospermia factor 1
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB
BLZF1 basic leucine zipper nuclear factor 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa
CCL14 chemokine (C-C motif) ligand 14
CCT2 chaperonin containing TCP1, subunit 2 (beta)
CCT4 chaperonin containing TCP1, subunit 4 (delta)
CCT7 chaperonin containing TCP1, subunit 7 (eta)
CDC14A cell division cycle 14A
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CHD1 chromodomain helicase DNA binding protein 1
CHEK1 checkpoint kinase 1
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
DMAP1 DNA methyltransferase 1 associated protein 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
DNAJB4 DnaJ (Hsp40) homolog, subfamily B, member 4
DNAJC21 DnaJ (Hsp40) homolog, subfamily C, member 21
DNMT1 DNA (cytosine-5-)-methyltransferase 1
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2
ENG endoglin
EPC1 enhancer of polycomb homolog 1 (Drosophila)
ESF1 ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
FPR3 formyl peptide receptor 3
GDF5 growth differentiation factor 5
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
ING2 inhibitor of growth family, member 2
INO80 INO80 complex subunit
KAT2A K(lysine) acetyltransferase 2A
MCM10 minichromosome maintenance complex component 10
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM4 minichromosome maintenance complex component 4
MCM5 minichromosome maintenance complex component 5
MCM6 minichromosome maintenance complex component 6
MCM7 minichromosome maintenance complex component 7
MEAF6 MYST/Esa1-associated factor 6
MORF4L1 mortality factor 4 like 1
NET1 neuroepithelial cell transforming 1
NOM1 nucleolar protein with MIF4G domain 1
ORC3 origin recognition complex, subunit 3
PFDN1 prefoldin subunit 1
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RNF20 ring finger protein 20, E3 ubiquitin protein ligase
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
RSL1D1 ribosomal L1 domain containing 1
RUVBL1 RuvB-like AAA ATPase 1
RUVBL2 RuvB-like AAA ATPase 2
SETD1A SET domain containing 1A
SIN3A SIN3 transcription regulator family member A
SKIV2L2 superkiller viralicidic activity 2-like 2 (S. cerevisiae)
SMARCC1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
SMC3 structural maintenance of chromosomes 3
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
SRCAP Snf2-related CREBBP activator protein
SRFBP1 serum response factor binding protein 1
SUPT16H suppressor of Ty 16 homolog (S. cerevisiae)
SUPT5H suppressor of Ty 5 homolog (S. cerevisiae)
TADA3 transcriptional adaptor 3
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TAF12 TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
TAF4 TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TAF6 TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
TCP1 t-complex 1
TRAF3IP2 TRAF3 interacting protein 2
TRIM21 tripartite motif containing 21
TROVE2 TROVE domain family, member 2
TRRAP transformation/transcription domain-associated protein
WDR46 WD repeat domain 46