ENPP1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description ectonucleotide pyrophosphatase/phosphodiesterase 1|This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5167)
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Genes

419 genes differentially expressed following the ENPP1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
INHBC inhibin, beta C 3.30859
SKOR1 SKI family transcriptional corepressor 1 3.30859
QRFPR pyroglutamylated RFamide peptide receptor 3.30859
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) 3.30859
CCL5 chemokine (C-C motif) ligand 5 3.30859
ZNF560 zinc finger protein 560 3.30859
PAX5 paired box 5 3.30859
FAM156B family with sequence similarity 156, member B 3.30859
CEP295NL CEP295 N-terminal like 3.30859
TUBB8 tubulin, beta 8 class VIII 3.30859
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide 3.30859
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 3.30859
SLC39A5 solute carrier family 39 (zinc transporter), member 5 3.30859
CABS1 calcium-binding protein, spermatid-specific 1 3.30859
AFM afamin 3.30859
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 3.30859
CARD18 caspase recruitment domain family, member 18 3.30859
SCGN secretagogin, EF-hand calcium binding protein 3.30859
KNG1 kininogen 1 3.30859
PLIN1 perilipin 1 3.30859
TEX13B testis expressed 13B 3.30859
DNASE1L2 deoxyribonuclease I-like 2 3.30859
PGBDF plakoglobin binding and degradation factor 3.30859
CNTNAP4 contactin associated protein-like 4 3.30859
NCF1 neutrophil cytosolic factor 1 3.30859
HYAL4 hyaluronoglucosaminidase 4 3.30859
AZGP1 alpha-2-glycoprotein 1, zinc-binding 3.30859
GFI1 growth factor independent 1 transcription repressor 3.30859
POSTN periostin, osteoblast specific factor 3.30859
LGALS4 lectin, galactoside-binding, soluble, 4 3.30859
MYO1A myosin IA 3.30859
PRDM8 PR domain containing 8 3.30859
FAM9B family with sequence similarity 9, member B 3.30859
ZNF804B zinc finger protein 804B 3.30859
PMCH pro-melanin-concentrating hormone 3.30859
FGF9 fibroblast growth factor 9 3.30859
PODN podocan 3.30859
SOST sclerostin 3.30859
RBP4 retinol binding protein 4, plasma 3.30859
AMIGO3 adhesion molecule with Ig-like domain 3 3.30859
PITX3 paired-like homeodomain 3 3.30859
MMP28 matrix metallopeptidase 28 3.30859
MMP20 matrix metallopeptidase 20 3.30859
DRP2 dystrophin related protein 2 3.30859
HCST hematopoietic cell signal transducer 3.30859
MS4A14 membrane-spanning 4-domains, subfamily A, member 14 3.30859
MOGAT2 monoacylglycerol O-acyltransferase 2 3.30859
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 3.30859
OR6A2 olfactory receptor, family 6, subfamily A, member 2 3.30859
CLEC5A C-type lectin domain family 5, member A 3.30859
CRIP1 cysteine-rich protein 1 (intestinal) 3.30859
TCP11 t-complex 11, testis-specific 3.30859
PNOC prepronociceptin 3.30859
NAA11 N(alpha)-acetyltransferase 11, NatA catalytic subunit 3.30859
CRYGN crystallin, gamma N 3.30859
PITX2 paired-like homeodomain 2 3.30859
OR9H1 olfactory receptor family 9 subfamily H member 1 pseudogene (gene/pseudogene) 3.30859
KASH5 KASH domain containing 5 3.30859
H1-6 H1.6 linker histone, cluster member 3.30859
SLC7A13 solute carrier family 7 (anionic amino acid transporter), member 13 3.30859
OTOF otoferlin 3.30859
MCHR2 melanin-concentrating hormone receptor 2 3.30859
AVPR1A arginine vasopressin receptor 1A 3.30859
PROP1 PROP paired-like homeobox 1 3.30859
SPEM1 spermatid maturation 1 3.30859
DNAAF1 dynein, axonemal, assembly factor 1 3.30859
KRT86 keratin 86, type II 3.30859
SLC1A7 solute carrier family 1 (glutamate transporter), member 7 3.30859
TMPRSS6 transmembrane protease, serine 6 3.30859
H2BC3 H2B clustered histone 3 3.30859
CHCT1 CHD1 helical C-terminal domain containing 1 3.30859
SAXO5 stabilizer of axonemal microtubules 5 3.30859
SPMIP9 sperm microtubule inner protein 9 3.30859
TEKTL1 tektin like 1 3.30859
TEX53 testis expressed 53 3.30859
STRIT1 small transmembrane regulator of ion transport 1 3.30859
ZNF593OS ZNF593 opposite strand 3.30859
TMEM238L transmembrane protein 238 like 3.30859
SMIM35 small integral membrane protein 35 3.30859
SMIM31 small integral membrane protein 31 3.30859
UBE2L5 ubiquitin conjugating enzyme E2 L5 3.30859
GARIN6 golgi associated RAB2 interactor family member 6 3.30859
ODAPH odontogenesis associated phosphoprotein 3.30859
SPATA22 spermatogenesis associated 22 3.30859
LY6H lymphocyte antigen 6 complex, locus H 3.30859
ADGRG1 adhesion G protein-coupled receptor G1 3.30859
ING5 inhibitor of growth family, member 5 3.30859
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 3.30859
TMEM235 transmembrane protein 235 3.30859
MAG myelin associated glycoprotein 3.30859
MTNR1B melatonin receptor 1B 3.30859
CCIN calicin 3.30859
ZNF436 zinc finger protein 436 3.30859
ELAVL4 ELAV like neuron-specific RNA binding protein 4 3.30859
OR2A25 olfactory receptor, family 2, subfamily A, member 25 3.30859
SLC22A11 solute carrier family 22 (organic anion/urate transporter), member 11 3.30859
KLHL35 kelch-like family member 35 3.30859
HSPB6 heat shock protein, alpha-crystallin-related, B6 3.30859
RUNX3 runt-related transcription factor 3 3.30859
GATA1 GATA binding protein 1 (globin transcription factor 1) 3.30859
DLK2 delta-like 2 homolog (Drosophila) 3.30859
NPIPB7 nuclear pore complex interacting protein family, member B7 3.30859
FGFBP1 fibroblast growth factor binding protein 1 3.30859
ABHD15 abhydrolase domain containing 15 3.30859
VCX3B variable charge, X-linked 3B 3.30859
BARX2 BARX homeobox 2 3.30859
TACR2 tachykinin receptor 2 3.30859
CLDN22 claudin 22 3.30859
C1QL4 complement component 1, q subcomponent-like 4 3.30859
BARHL1 BarH-like homeobox 1 3.30859
KLRF1 killer cell lectin-like receptor subfamily F, member 1 3.30859
WEE2 WEE1 homolog 2 (S. pombe) 3.30859
ANKRD30B ankyrin repeat domain 30B 3.30859
TOPAZ1 testis and ovary specific PAZ domain containing 1 3.30859
TMEM132E transmembrane protein 132E 3.30859
CH25H cholesterol 25-hydroxylase 3.30859
APLNR apelin receptor 3.30859
CERKL ceramide kinase-like 3.30859
THTPA thiamine triphosphatase 3.30859
DPRX divergent-paired related homeobox 3.30859
FCRLA Fc receptor-like A 3.30859
COL9A2 collagen, type IX, alpha 2 3.30859
LRCOL1 leucine rich colipase-like 1 3.30859
CABP5 calcium binding protein 5 3.30859
MEIS1 Meis homeobox 1 3.30859
NR5A1 nuclear receptor subfamily 5, group A, member 1 3.30859
PDCD1 programmed cell death 1 3.30859
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) 3.30859
C11ORF16 chromosome 11 open reading frame 16 3.30859
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 3.30859
CPZ carboxypeptidase Z 3.30859
CLEC7A C-type lectin domain family 7, member A 3.30859
TPSG1 tryptase gamma 1 3.30859
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8 3.30859
CRYBA4 crystallin, beta A4 3.30859
PSKH2 protein serine kinase H2 3.30859
HOPX HOP homeobox 3.30859
RGCC regulator of cell cycle 3.30859
SNX31 sorting nexin 31 3.30859
IFNL4 interferon, lambda 4 (gene/pseudogene) 3.30859
DNTT DNA nucleotidylexotransferase 3.30859
SHISA8 shisa family member 8 3.30859
DSC1 desmocollin 1 3.30859
LRRC15 leucine rich repeat containing 15 3.30859
TRADD TNFRSF1A-associated via death domain 3.30859
LCN1 lipocalin 1 3.30859
VWA7 von Willebrand factor A domain containing 7 3.30859
ERICH6B glutamate-rich 6B 3.30859
GML glycosylphosphatidylinositol anchored molecule like 3.30859
WFDC8 WAP four-disulfide core domain 8 3.30859
LY96 lymphocyte antigen 96 3.30859
SULT2A1 sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1 3.30859
CALR3 calreticulin 3 3.30859
LMOD2 leiomodin 2 (cardiac) 3.30859
PGR progesterone receptor 3.30859
DRC7 dynein regulatory complex subunit 7 3.30859
RIPK3 receptor-interacting serine-threonine kinase 3 3.30859
PCDHAC2 protocadherin alpha subfamily C, 2 3.30859
HHIPL2 HHIP-like 2 3.30859
CARD11 caspase recruitment domain family, member 11 3.30859
GOLGA8J golgin A8 family, member J 3.30859
SOX30 SRY (sex determining region Y)-box 30 3.30859
TEX29 testis expressed 29 3.30859
TAS2R43 taste receptor, type 2, member 43 3.30859
HLA-DMB major histocompatibility complex, class II, DM beta 3.30859
OPALIN oligodendrocytic myelin paranodal and inner loop protein 3.30859
ADAM20 ADAM metallopeptidase domain 20 3.30859
ADRA1B adrenoceptor alpha 1B 3.30859
TGM7 transglutaminase 7 3.30859
FRMPD1 FERM and PDZ domain containing 1 3.30859
MYOZ2 myozenin 2 3.30859
AMER2 APC membrane recruitment protein 2 3.30859
IDI2 isopentenyl-diphosphate delta isomerase 2 3.30859
TMIGD3 transmembrane and immunoglobulin domain containing 3 3.30859
PLCD4 phospholipase C, delta 4 3.30859
GPR50 G protein-coupled receptor 50 3.30859
RGS8 regulator of G-protein signaling 8 3.30859
IRX4 iroquois homeobox 4 3.30859
CD27 CD27 molecule 3.30859
IL17B interleukin 17B 3.30859
PLGLB2 plasminogen-like B2 3.30859
LY6G6D lymphocyte antigen 6 complex, locus G6D 3.30859
ART1 ADP-ribosyltransferase 1 3.30859
GLRX3 glutaredoxin 3 3.26458
XIRP2 xin actin binding repeat containing 2 3.18252
DAXX death-domain associated protein 3.06414
RBMS3 RNA binding motif, single stranded interacting protein 3 2.97945
CCL2 chemokine (C-C motif) ligand 2 2.95006
MT1X metallothionein 1X 2.91804
ZNF711 zinc finger protein 711 2.85312
CC2D1A coiled-coil and C2 domain containing 1A 2.81116
CFAP298 cilia and flagella associated protein 298 2.79716
IFITM3 interferon induced transmembrane protein 3 2.77519
RIC3 RIC3 acetylcholine receptor chaperone 2.76658
CFAP100 cilia and flagella associated protein 100 2.76658
IER2 immediate early response 2 2.72292
HIBCH 3-hydroxyisobutyryl-CoA hydrolase 2.70338
ENOPH1 enolase-phosphatase 1 2.69436
H3-3B H3.3 histone B 2.69044
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 2.64138
GAPDH glyceraldehyde-3-phosphate dehydrogenase 2.63479
FAT1 FAT atypical cadherin 1 2.63013
ANK1 ankyrin 1, erythrocytic 2.60712
RARRES2 retinoic acid receptor responder (tazarotene induced) 2 2.60712
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 2.54941
CPLX4 complexin 4 2.54941
VN1R1 vomeronasal 1 receptor 1 2.54941
TIGD3 tigger transposable element derived 3 2.54941
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) 2.5373
TMEM165 transmembrane protein 165 2.52718
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2 2.46753
EDF1 endothelial differentiation-related factor 1 2.4518
ORAI3 ORAI calcium release-activated calcium modulator 3 2.42483
MAGT1 magnesium transporter 1 2.42483
C6ORF136 chromosome 6 open reading frame 136 2.40249
TBC1D7-LOC100130357 TBC1D7-LOC100130357 readthrough 2.39184
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1 2.37944
TENT5B terminal nucleotidyltransferase 5B 2.3783
ADARB1 adenosine deaminase, RNA-specific, B1 2.37783
AHRR aryl-hydrocarbon receptor repressor 2.37673
COX6C cytochrome c oxidase subunit VIc 2.36938
CHRM3 cholinergic receptor, muscarinic 3 2.36868
CDC50B cell division cycle 50 P4-ATPase accessory subunit B 2.36419
KCNMB2 potassium channel subfamily M regulatory beta subunit 2 2.33932
GRM5 glutamate receptor, metabotropic 5 2.33835
SKP1 S-phase kinase-associated protein 1 2.33626
ATP5MG ATP synthase membrane subunit g 2.33291
COXFA4 cytochrome c oxidase associated subunit FA4 2.33227
CAPS calcyphosine 2.32873
RAB38 RAB38, member RAS oncogene family 2.32036
CCDC102B coiled-coil domain containing 102B 2.31267
ART5 ADP-ribosyltransferase 5 2.31267
UNC119 unc-119 homolog (C. elegans) 2.26265
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 2.26122
MALT1 MALT1 paracaspase 2.25958
RPL30 ribosomal protein L30 2.24973
ANKRD36C ankyrin repeat domain 36C 2.2484
PRG4 proteoglycan 4 2.22402
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 2.22402
ARHGEF9 Cdc42 guanine nucleotide exchange factor (GEF) 9 2.22154
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 2.21566
LBHD1 LBH domain containing 1 2.21147
CFAP99 cilia and flagella associated protein 99 2.21147
GGH gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase) 2.21147
PNMA8C PNMA family member 8C 2.21147
KHDC3L KH domain containing 3-like, subcortical maternal complex member 2.21147
EYS eyes shut homolog (Drosophila) 2.20208
NQO1 NAD(P)H dehydrogenase, quinone 1 2.19283
CHMP5 charged multivesicular body protein 5 2.17913
PDZRN3 PDZ domain containing ring finger 3 2.15637
ATP5MK ATP synthase membrane subunit k 2.15637
EGF epidermal growth factor 2.14052
DUT deoxyuridine triphosphatase 2.13863
RPS6 ribosomal protein S6 2.12027
THOC7 THO complex 7 2.11725
HAGHL hydroxyacylglutathione hydrolase-like 2.1088
PPP1R21 protein phosphatase 1, regulatory subunit 21 2.09562
TMEM167A transmembrane protein 167A 2.07555
DRAM2 DNA-damage regulated autophagy modulator 2 2.07555
TUBA1B tubulin, alpha 1b 2.07143
ARHGAP11A Rho GTPase activating protein 11A 2.07143
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 2.06643
GABPA GA binding protein transcription factor, alpha subunit 60kDa 2.06507
GSTP1 glutathione S-transferase pi 1 2.06495
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7 2.0649
PPP3CA protein phosphatase 3, catalytic subunit, alpha isozyme 2.05859
CFAP95 cilia and flagella associated protein 95 2.05608
EME2 essential meiotic structure-specific endonuclease subunit 2 2.05224
COX4I1 cytochrome c oxidase subunit IV isoform 1 2.0496
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1 2.04235
KIF18A kinesin family member 18A 2.03798
ARL11 ADP-ribosylation factor-like 11 2.03321
AMER1 APC membrane recruitment protein 1 2.0316
GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase 2.03059
AIRIM AFG2 interacting ribosome maturation factor 2.03059
NUDT19 nudix (nucleoside diphosphate linked moiety X)-type motif 19 2.02848
ARF5 ADP-ribosylation factor 5 2.01946
ISCA1 iron-sulfur cluster assembly 1 2.01806
BEX5 brain expressed, X-linked 5 2.01806
RPL5 ribosomal protein L5 2.00374
PUS1 pseudouridylate synthase 1 2.00374

decreased expression

Symbol Name Standardized Value
PKP1 plakophilin 1 -3.30859
AOC1 amine oxidase, copper containing 1 -3.30859
DNAH6 dynein, axonemal, heavy chain 6 -3.30859
ACAN aggrecan -3.30859
OR2A14 olfactory receptor, family 2, subfamily A, member 14 -3.30859
TMEM86A transmembrane protein 86A -3.30859
MIXL1 Mix paired-like homeobox -3.30859
SDR16C5 short chain dehydrogenase/reductase family 16C, member 5 -3.30859
ABHD1 abhydrolase domain containing 1 -3.30859
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 -3.30859
TMEM234 transmembrane protein 234 -3.30859
CCNB3 cyclin B3 -3.30859
IL11RA interleukin 11 receptor, alpha -3.30859
ENPP1 ectonucleotide pyrophosphatase/phosphodiesterase 1 -3.30859
GABRA4 gamma-aminobutyric acid (GABA) A receptor, alpha 4 -3.30859
LOX lysyl oxidase -3.30859
ZNF99 zinc finger protein 99 -3.30859
ATP13A4 ATPase type 13A4 -3.30859
CAPN11 calpain 11 -3.30859
RTKN rhotekin -3.30859
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 -3.30859
PROC protein C (inactivator of coagulation factors Va and VIIIa) -3.30859
TUBA4B tubulin, alpha 4b -3.30859
LMX1B LIM homeobox transcription factor 1, beta -3.30859
ACSL5 acyl-CoA synthetase long-chain family member 5 -3.30859
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 -3.30859
GPR12 G protein-coupled receptor 12 -3.30859
EDN1 endothelin 1 -3.30859
RBM6 RNA binding motif protein 6 -3.24338
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase -3.14602
RORB RAR-related orphan receptor B -3.14601
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -3.03704
NKD1 naked cuticle homolog 1 (Drosophila) -3.0046
AOAH acyloxyacyl hydrolase (neutrophil) -2.92553
NEFH neurofilament, heavy polypeptide -2.90192
PRUNE1 prune exopolyphosphatase 1 -2.90027
CELF1 CUGBP, Elav-like family member 1 -2.88826
FBXW2 F-box and WD repeat domain containing 2 -2.88124
H2BC17 H2B clustered histone 17 -2.87649
ITLN2 intelectin 2 -2.87649
ADGRE5 adhesion G protein-coupled receptor E5 -2.87649
ADAM32 ADAM metallopeptidase domain 32 -2.86589
MRE11 MRE11 homolog, double strand break repair nuclease -2.81116
LYSMD3 LysM, putative peptidoglycan-binding, domain containing 3 -2.80397
IL20RB interleukin 20 receptor beta -2.7858
C2 complement component 2 -2.69236
TCEA2 transcription elongation factor A (SII), 2 -2.65957
SQSTM1 sequestosome 1 -2.63653
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator -2.62575
DGKA diacylglycerol kinase, alpha 80kDa -2.60729
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5 -2.60712
CLCC1 chloride channel CLIC-like 1 -2.60712
RANGAP1 Ran GTPase activating protein 1 -2.58316
TRIM3 tripartite motif containing 3 -2.56725
RAB24 RAB24, member RAS oncogene family -2.56443
BEST2 bestrophin 2 -2.54941
ASB18 ankyrin repeat and SOCS box containing 18 -2.54941
ATAD3C ATPase family, AAA domain containing 3C -2.54941
GOLGA6L7 golgin A6 family like 7 -2.54941
HS3ST3A1 heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 -2.5373
SCUBE2 signal peptide, CUB domain, EGF-like 2 -2.50074
INIP INTS3 and NABP interacting protein -2.44049
RECQL5 RecQ protein-like 5 -2.42943
AGK acylglycerol kinase -2.42636
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) -2.42483
NAA50 N(alpha)-acetyltransferase 50, NatE catalytic subunit -2.42253
ANKZF1 ankyrin repeat and zinc finger domain containing 1 -2.41323
PSD4 pleckstrin and Sec7 domain containing 4 -2.3975
GPA33 glycoprotein A33 (transmembrane) -2.3975
SLC24A4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 -2.3975
CLPSL1 colipase-like 1 -2.3975
F10 coagulation factor X -2.3975
CCN2 cellular communication network factor 2 -2.3975
ZSCAN22 zinc finger and SCAN domain containing 22 -2.3975
LLGL1 lethal giant larvae homolog 1 (Drosophila) -2.37737
LRRC9 leucine rich repeat containing 9 -2.37189
ANKRD65 ankyrin repeat domain 65 -2.34388
CD200R1L CD200 receptor 1-like -2.34388
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.33932
NIBAN1 niban apoptosis regulator 1 -2.3333
WBP2NL WBP2 N-terminal like -2.33016
PCDH9 protocadherin 9 -2.33016
STIL SCL/TAL1 interrupting locus -2.32851
SHC1 SHC (Src homology 2 domain containing) transforming protein 1 -2.32036
CYGB cytoglobin -2.31267
PAPLN papilin, proteoglycan-like sulfated glycoprotein -2.31267
SFXN5 sideroflexin 5 -2.29609
SUGP2 SURP and G patch domain containing 2 -2.28426
UBFD1 ubiquitin family domain containing 1 -2.27631
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) -2.26897
YARS1 tyrosyl-tRNA synthetase 1 -2.26787
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit -2.26574
CCDC97 coiled-coil domain containing 97 -2.24929
CISD2 CDGSH iron sulfur domain 2 -2.24427
PIGK phosphatidylinositol glycan anchor biosynthesis, class K -2.23494
NLE1 notchless homolog 1 (Drosophila) -2.21566
HMGN4 high mobility group nucleosomal binding domain 4 -2.21023
ECD ecdysoneless homolog (Drosophila) -2.20414
CLTRN collectrin, amino acid transport regulator -2.19283
SLCO4C1 solute carrier organic anion transporter family, member 4C1 -2.18581
QTRT2 queuine tRNA-ribosyltransferase accessory subunit 2 -2.17221
SAFB2 scaffold attachment factor B2 -2.1719
CCND2 cyclin D2 -2.1719
ZNF790 zinc finger protein 790 -2.16315
MED20 mediator complex subunit 20 -2.15637
ILDR1 immunoglobulin-like domain containing receptor 1 -2.14855
MAP2K5 mitogen-activated protein kinase kinase 5 -2.13682
TMEM198 transmembrane protein 198 -2.1323
SHMT1 serine hydroxymethyltransferase 1 (soluble) -2.1276
KDM6A lysine (K)-specific demethylase 6A -2.12331
VMA22 vacuolar ATPase assembly factor VMA22 -2.11725
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase -2.11725
FZD2 frizzled class receptor 2 -2.11725
FBLN5 fibulin 5 -2.09417
DOCK6 dedicator of cytokinesis 6 -2.0901
FGF13 fibroblast growth factor 13 -2.08493
SPEG SPEG complex locus -2.07894
TM9SF1 transmembrane 9 superfamily member 1 -2.07555
INSR insulin receptor -2.07555
ZNF101 zinc finger protein 101 -2.07555
EFHC2 EF-hand domain (C-terminal) containing 2 -2.07555
RNF168 ring finger protein 168, E3 ubiquitin protein ligase -2.07555
SLC25A20 solute carrier family 25 (carnitine/acylcarnitine translocase), member 20 -2.07555
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1 -2.07555
HEATR6 HEAT repeat containing 6 -2.07295
CD4 CD4 molecule -2.07096
ANKAR ankyrin and armadillo repeat containing -2.06507
CSKMT citrate synthase lysine methyltransferase -2.06141
UBR4 ubiquitin protein ligase E3 component n-recognin 4 -2.05656
KCNIP1 Kv channel interacting protein 1 -2.03798
PRKD3 protein kinase D3 -2.03426
TRIM58 tripartite motif containing 58 -2.0316
NOL6 nucleolar protein 6 (RNA-associated) -2.02442
TXNL4B thioredoxin-like 4B -2.01806
UBN2 ubinuclein 2 -2.01035
GJA1 gap junction protein, alpha 1, 43kDa -2.00965
NEK10 NIMA-related kinase 10 -2.00769
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 -2.00121