| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | ectonucleotide pyrophosphatase/phosphodiesterase 1|This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5167) |
| External Link | https://ncbi.nlm.nih.gov/gene/5167 |
| Similar Terms | |
| Downloads & Tools |
497 genes differentially expressed following the ENPP1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0220648 |
| S100A8 | S100 calcium binding protein A8 | 0.0196094 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | 0.0173394 |
| KDM5D | lysine (K)-specific demethylase 5D | 0.0156841 |
| MT1G | metallothionein 1G | 0.0127012 |
| S100A9 | S100 calcium binding protein A9 | 0.0121852 |
| MT1X | metallothionein 1X | 0.0118889 |
| S100A7 | S100 calcium binding protein A7 | 0.0117929 |
| MAGEA3 | melanoma antigen family A3 | 0.0116532 |
| MT1H | metallothionein 1H | 0.0113726 |
| BAMBI | BMP and activin membrane-bound inhibitor | 0.011063 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0109351 |
| MT1F | metallothionein 1F | 0.0106388 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0102393 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0100289 |
| PITX3 | paired-like homeodomain 3 | 0.00999986 |
| PI3 | peptidase inhibitor 3, skin-derived | 0.00992534 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00981045 |
| EFEMP1 | EGF containing fibulin-like extracellular matrix protein 1 | 0.00931857 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00924074 |
| AREG | amphiregulin | 0.00919162 |
| AMIGO2 | adhesion molecule with Ig-like domain 2 | 0.00907865 |
| MT1E | metallothionein 1E | 0.00905783 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.00889585 |
| MAL | mal, T-cell differentiation protein | 0.00889137 |
| EVI2A | ecotropic viral integration site 2A | 0.00884075 |
| H1-2 | H1.2 linker histone, cluster member | 0.00876695 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.00865488 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.00861902 |
| NRCAM | neuronal cell adhesion molecule | 0.00856562 |
| MEF2C | myocyte enhancer factor 2C | 0.00843599 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.00840925 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 0.00826539 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00825686 |
| DPYD | dihydropyrimidine dehydrogenase | 0.00823932 |
| HIST1H2AC | histone cluster 1, H2ac | 0.00811523 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.00808398 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | 0.00807685 |
| VTCN1 | V-set domain containing T cell activation inhibitor 1 | 0.00805096 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00792031 |
| PFKL | phosphofructokinase, liver | 0.00782155 |
| VLDLR | very low density lipoprotein receptor | 0.00775217 |
| TP53I3 | tumor protein p53 inducible protein 3 | 0.00775213 |
| KRT6B | keratin 6B, type II | 0.00772363 |
| GPM6A | glycoprotein M6A | 0.00770075 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00763121 |
| DEFB1 | defensin, beta 1 | 0.0075487 |
| MCUB | mitochondrial calcium uniporter dominant negative subunit beta | 0.00751448 |
| MT2A | metallothionein 2A | 0.00749829 |
| SCRG1 | stimulator of chondrogenesis 1 | 0.00742308 |
| PROM1 | prominin 1 | 0.00741972 |
| VNN1 | vanin 1 | 0.00741594 |
| PRAME | preferentially expressed antigen in melanoma | 0.00739182 |
| KRT7 | keratin 7, type II | 0.00735882 |
| KRT81 | keratin 81, type II | 0.0072735 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.00725096 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.00723581 |
| LINC00623 | long intergenic non-protein coding RNA 623 | 0.00718652 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | 0.00712055 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00710951 |
| SDC1 | syndecan 1 | 0.00707725 |
| RHOBTB1 | Rho-related BTB domain containing 1 | 0.00707361 |
| MX2 | MX dynamin-like GTPase 2 | 0.00706693 |
| KIAA0100 | KIAA0100 | 0.00701917 |
| ELK3 | ELK3, ETS-domain protein (SRF accessory protein 2) | 0.00701829 |
| PLK1 | polo-like kinase 1 | 0.00699112 |
| HSPA1A | heat shock 70kDa protein 1A | 0.00698239 |
| CLTB | clathrin, light chain B | 0.0069518 |
| EDN3 | endothelin 3 | 0.00681097 |
| GNG11 | guanine nucleotide binding protein (G protein), gamma 11 | 0.00675986 |
| DDX58 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 | 0.00675503 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.00675442 |
| PLK2 | polo-like kinase 2 | 0.00675333 |
| ANXA1 | annexin A1 | 0.00674207 |
| CD38 | CD38 molecule | 0.00671666 |
| KRT5 | keratin 5, type II | 0.00661495 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | 0.00658503 |
| CRYAB | crystallin, alpha B | 0.00657138 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.00654847 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00649363 |
| MMRN1 | multimerin 1 | 0.0064807 |
| AOX1 | aldehyde oxidase 1 | 0.0064494 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | 0.00644319 |
| ARL2 | ADP-ribosylation factor-like 2 | 0.00642756 |
| COL11A1 | collagen, type XI, alpha 1 | 0.00642755 |
| WASHC4 | WASH complex subunit 4 | 0.00642457 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | 0.00642066 |
| USP9Y | ubiquitin specific peptidase 9, Y-linked | 0.00640748 |
| NAV3 | neuron navigator 3 | 0.00640734 |
| RHCG | Rh family, C glycoprotein | 0.00636178 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00634767 |
| ACKR3 | atypical chemokine receptor 3 | 0.00634449 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00631162 |
| TFEC | transcription factor EC | 0.00628438 |
| QKI | QKI, KH domain containing, RNA binding | 0.0062495 |
| SLC1A1 | solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 | 0.00624815 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | 0.00618581 |
| CCNA2 | cyclin A2 | 0.00618197 |
| EIF3G | eukaryotic translation initiation factor 3, subunit G | 0.00618164 |
| HSPA2 | heat shock 70kDa protein 2 | 0.00613438 |
| SLC7A7 | solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 | 0.00611161 |
| DOK5 | docking protein 5 | 0.00610883 |
| GIMAP6 | GTPase, IMAP family member 6 | 0.00610819 |
| KRT14 | keratin 14, type I | 0.0060845 |
| EFHD1 | EF-hand domain family, member D1 | 0.00607278 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00607056 |
| CSRP2 | cysteine and glycine-rich protein 2 | 0.0060656 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | 0.00605866 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00604625 |
| IFI44 | interferon-induced protein 44 | 0.00603785 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | 0.00602303 |
| PMP2 | peripheral myelin protein 2 | 0.00599898 |
| COMT | catechol-O-methyltransferase | 0.00599549 |
| GAP43 | growth associated protein 43 | 0.00599085 |
| RB1 | retinoblastoma 1 | 0.00594472 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00592601 |
| BMP6 | bone morphogenetic protein 6 | 0.00592498 |
| RND3 | Rho family GTPase 3 | 0.00590814 |
| UPP1 | uridine phosphorylase 1 | 0.00590204 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | 0.00589268 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.00587969 |
| PUF60 | poly-U binding splicing factor 60KDa | 0.00586784 |
| CCR2 | chemokine (C-C motif) receptor 2 | 0.00585993 |
| CD34 | CD34 molecule | 0.00585274 |
| MKKS | McKusick-Kaufman syndrome | 0.00583974 |
| JUNB | jun B proto-oncogene | 0.0058153 |
| IFT20 | intraflagellar transport 20 | 0.00579953 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | 0.0057944 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.00578658 |
| ATF3 | activating transcription factor 3 | 0.00577245 |
| SGCE | sarcoglycan, epsilon | 0.00576608 |
| GLDC | glycine dehydrogenase (decarboxylating) | 0.00574483 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00573441 |
| THEMIS2 | thymocyte selection associated family member 2 | 0.00573342 |
| SP110 | SP110 nuclear body protein | 0.00572796 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 0.00572253 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.00572238 |
| CALB1 | calbindin 1, 28kDa | 0.00571358 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00569017 |
| S100A12 | S100 calcium binding protein A12 | 0.00566084 |
| TNFAIP1 | tumor necrosis factor, alpha-induced protein 1 (endothelial) | 0.00565892 |
| TEK | TEK tyrosine kinase, endothelial | 0.00564373 |
| PRDX4 | peroxiredoxin 4 | 0.00563678 |
| KRT6A | keratin 6A, type II | 0.00559577 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.00558328 |
| CRNN | cornulin | 0.00556345 |
| KLF2 | Kruppel-like factor 2 | 0.00548064 |
| TSPO | translocator protein (18kDa) | 0.00547623 |
| FOXG1 | forkhead box G1 | 0.00544692 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | 0.00544524 |
| ACAT1 | acetyl-CoA acetyltransferase 1 | 0.00544414 |
| LPIN1 | lipin 1 | 0.00541099 |
| MS4A6A | membrane-spanning 4-domains, subfamily A, member 6A | 0.00540691 |
| ANOS1 | anosmin 1 | 0.00540246 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00540014 |
| IFI35 | interferon-induced protein 35 | 0.00538555 |
| H1-10 | H1.10 linker histone | 0.00537386 |
| RGS2 | regulator of G-protein signaling 2 | 0.00537314 |
| FGF1 | fibroblast growth factor 1 (acidic) | 0.00536465 |
| LACTB2 | lactamase, beta 2 | 0.00535866 |
| PEG10 | paternally expressed 10 | 0.00534418 |
| COMMD3 | COMM domain containing 3 | 0.00533725 |
| LZTFL1 | leucine zipper transcription factor-like 1 | 0.00532973 |
| TNFRSF17 | tumor necrosis factor receptor superfamily, member 17 | 0.00531645 |
| MKNK1 | MAP kinase interacting serine/threonine kinase 1 | 0.00530384 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | 0.00529625 |
| HIST1H2BK | histone cluster 1, H2bk | 0.00529133 |
| BLNK | B-cell linker | 0.0052888 |
| ADSL | adenylosuccinate lyase | 0.00527946 |
| MS4A4A | membrane-spanning 4-domains, subfamily A, member 4A | 0.00527864 |
| PSAP | prosaposin | 0.00526895 |
| ERGIC3 | ERGIC and golgi 3 | 0.00525809 |
| MX1 | MX dynamin-like GTPase 1 | 0.00525714 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.00523221 |
| TNNC1 | troponin C type 1 (slow) | 0.00523112 |
| LRRN3 | leucine rich repeat neuronal 3 | 0.00520391 |
| ALDH3B2 | aldehyde dehydrogenase 3 family, member B2 | 0.00520093 |
| S100A2 | S100 calcium binding protein A2 | 0.00520039 |
| ARPC4 | actin related protein 2/3 complex, subunit 4, 20kDa | 0.00517084 |
| MAPKAPK5 | mitogen-activated protein kinase-activated protein kinase 5 | 0.00516977 |
| PNMA2 | paraneoplastic Ma antigen 2 | 0.00512667 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B | 0.00511794 |
| SUCLG1 | succinate-CoA ligase, alpha subunit | 0.00510255 |
| HDAC9 | histone deacetylase 9 | 0.00510019 |
| PPP2R3C | protein phosphatase 2, regulatory subunit B'', gamma | 0.00509746 |
| FXYD5 | FXYD domain containing ion transport regulator 5 | 0.00508433 |
| GFAP | glial fibrillary acidic protein | 0.00508275 |
| EML3 | echinoderm microtubule associated protein like 3 | 0.0050792 |
| IFI44L | interferon-induced protein 44-like | 0.00507745 |
| JUP | junction plakoglobin | 0.00507198 |
| F13A1 | coagulation factor XIII, A1 polypeptide | 0.00506811 |
| RCAN1 | regulator of calcineurin 1 | 0.00505062 |
| VPS51 | vacuolar protein sorting 51 homolog (S. cerevisiae) | 0.00503888 |
| RBKS | ribokinase | 0.00503111 |
| SSR2 | signal sequence receptor, beta (translocon-associated protein beta) | 0.00501877 |
| BMP7 | bone morphogenetic protein 7 | 0.00501805 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.00500981 |
| TMEM100 | transmembrane protein 100 | 0.00500446 |
| MAGEA12 | melanoma antigen family A12 | 0.00499706 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.00499295 |
| FZD6 | frizzled class receptor 6 | 0.00498447 |
| CYBB | cytochrome b-245, beta polypeptide | 0.00497917 |
| SERPINB6 | serpin peptidase inhibitor, clade B (ovalbumin), member 6 | 0.0049751 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.00496399 |
| MSR1 | macrophage scavenger receptor 1 | 0.00494773 |
| APBB1IP | amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein | 0.00494418 |
| APRT | adenine phosphoribosyltransferase | 0.00494415 |
| ANKRD28 | ankyrin repeat domain 28 | 0.00494172 |
| TBXA2R | thromboxane A2 receptor | 0.00494018 |
| ATRAID | all-trans retinoic acid-induced differentiation factor | 0.00493736 |
| GIMAP4 | GTPase, IMAP family member 4 | 0.00492654 |
| XPNPEP2 | X-prolyl aminopeptidase (aminopeptidase P) 2, membrane-bound | 0.00488373 |
| MSRA | methionine sulfoxide reductase A | 0.00488043 |
| KRT13 | keratin 13, type I | 0.0048767 |
| TMEM140 | transmembrane protein 140 | 0.00487298 |
| GCA | grancalcin, EF-hand calcium binding protein | 0.00487093 |
| TTTY15 | testis-specific transcript, Y-linked 15 (non-protein coding) | 0.00486253 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.00486078 |
| PRKCSH | protein kinase C substrate 80K-H | 0.00485892 |
| EPHA2 | EPH receptor A2 | 0.0048581 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.00483118 |
| AHCY | adenosylhomocysteinase | 0.00482822 |
| PODXL | podocalyxin-like | 0.00481865 |
| HSF1 | heat shock transcription factor 1 | 0.00481439 |
| EDEM2 | ER degradation enhancer, mannosidase alpha-like 2 | 0.00480616 |
| ME3 | malic enzyme 3, NADP(+)-dependent, mitochondrial | 0.00480467 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 0.00480051 |
| SLC39A4 | solute carrier family 39 (zinc transporter), member 4 | 0.00479724 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.00478153 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | 0.00477846 |
| GMPS | guanine monphosphate synthase | 0.0047659 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger | 0.00476585 |
| PLSCR4 | phospholipid scramblase 4 | 0.00475658 |
| RRAGD | Ras-related GTP binding D | 0.00473741 |
| NDRG1 | N-myc downstream regulated 1 | 0.00472958 |
| IFIT5 | interferon-induced protein with tetratricopeptide repeats 5 | 0.00472446 |
| CDCA4 | cell division cycle associated 4 | 0.00471829 |
| SYNM | synemin, intermediate filament protein | 0.00471229 |
| CDC42 | cell division cycle 42 | 0.0047029 |
| ICAM2 | intercellular adhesion molecule 2 | 0.00470248 |
| PFKP | phosphofructokinase, platelet | 0.00470106 |
| TPD52L1 | tumor protein D52-like 1 | 0.00468894 |
| BHLHE41 | basic helix-loop-helix family, member e41 | 0.00468094 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00467823 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.00467123 |
| MME | membrane metallo-endopeptidase | 0.00466647 |
| TDO2 | tryptophan 2,3-dioxygenase | 0.00466571 |
| SPRR3 | small proline-rich protein 3 | 0.00466179 |
| Symbol | Name | Standardized Value |
|---|---|---|
| XIC | X chromosome inactivation center | -0.0260438 |
| CHP1 | calcineurin-like EF-hand protein 1 | -0.0164985 |
| SMC1A | structural maintenance of chromosomes 1A | -0.0140176 |
| SIRT3 | sirtuin 3 | -0.0129785 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.0127774 |
| STK10 | serine/threonine kinase 10 | -0.01223 |
| MSMB | microseminoprotein, beta- | -0.0121321 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0116066 |
| AUTS2 | autism susceptibility candidate 2 | -0.0114967 |
| A2M | alpha-2-macroglobulin | -0.0112249 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | -0.0110969 |
| CCL19 | chemokine (C-C motif) ligand 19 | -0.010884 |
| CHKB | choline kinase beta | -0.0108824 |
| CYP2B6 | cytochrome P450, family 2, subfamily B, polypeptide 6 | -0.0105355 |
| SRD5A1 | steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1) | -0.0102527 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.0100318 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | -0.009954 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.00974049 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00961618 |
| TSPAN8 | tetraspanin 8 | -0.00945028 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.00930722 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.0091554 |
| CXCL13 | chemokine (C-X-C motif) ligand 13 | -0.00913511 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00911626 |
| CXCL9 | chemokine (C-X-C motif) ligand 9 | -0.00911584 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | -0.00904231 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00893002 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | -0.0088529 |
| DHCR24 | 24-dehydrocholesterol reductase | -0.00868354 |
| TNS1 | tensin 1 | -0.00856771 |
| EPCAM | epithelial cell adhesion molecule | -0.0085471 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.00852369 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00841751 |
| PIP | prolactin-induced protein | -0.0083035 |
| SFTPC | surfactant protein C | -0.00829168 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | -0.0082238 |
| ADCY1 | adenylate cyclase 1 (brain) | -0.00807307 |
| CD52 | CD52 molecule | -0.00807112 |
| TOX3 | TOX high mobility group box family member 3 | -0.0080446 |
| COL6A3 | collagen, type VI, alpha 3 | -0.00800202 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00795376 |
| PRUNE2 | prune homolog 2 (Drosophila) | -0.00794654 |
| NEFH | neurofilament, heavy polypeptide | -0.00787578 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.00770676 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00765025 |
| TARP | TCR gamma alternate reading frame protein | -0.00750114 |
| PCP4 | Purkinje cell protein 4 | -0.00741505 |
| SORD | sorbitol dehydrogenase | -0.00733676 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.00729839 |
| TLCD3A | TLC domain containing 3A | -0.00728518 |
| RET | ret proto-oncogene | -0.00727186 |
| ASS1 | argininosuccinate synthase 1 | -0.00722283 |
| CLDN3 | claudin 3 | -0.00721719 |
| TFF3 | trefoil factor 3 (intestinal) | -0.00721583 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.00718522 |
| DCLK1 | doublecortin-like kinase 1 | -0.00718371 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00718173 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00713675 |
| AGR2 | anterior gradient 2 | -0.007129 |
| NFATC3 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 | -0.00710364 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00709859 |
| LTF | lactotransferrin | -0.00708242 |
| PCNA | proliferating cell nuclear antigen | -0.00706875 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00700044 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.00693478 |
| PURA | purine-rich element binding protein A | -0.0069237 |
| PER3 | period circadian clock 3 | -0.00691628 |
| FASN | fatty acid synthase | -0.00689313 |
| SLC16A6 | solute carrier family 16, member 6 | -0.00686739 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 | -0.00685677 |
| BPIFA1 | BPI fold containing family A, member 1 | -0.0068371 |
| ARG1 | arginase 1 | -0.00681013 |
| ALDH5A1 | aldehyde dehydrogenase 5 family, member A1 | -0.00677943 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | -0.00675826 |
| CFB | complement factor B | -0.0067194 |
| LUM | lumican | -0.00671015 |
| NKX3-1 | NK3 homeobox 1 | -0.00664478 |
| APOD | apolipoprotein D | -0.00660666 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00660084 |
| SFTPA2 | surfactant protein A2 | -0.00659977 |
| OLFM1 | olfactomedin 1 | -0.00656624 |
| DEGS1 | delta(4)-desaturase, sphingolipid 1 | -0.00650618 |
| SFTPD | surfactant protein D | -0.00649876 |
| LPCAT1 | lysophosphatidylcholine acyltransferase 1 | -0.00649378 |
| RAB20 | RAB20, member RAS oncogene family | -0.00647033 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.00645373 |
| KCND3 | potassium channel, voltage gated Shal related subfamily D, member 3 | -0.00645228 |
| SLC26A2 | solute carrier family 26 (anion exchanger), member 2 | -0.00644183 |
| PTK2 | protein tyrosine kinase 2 | -0.00643964 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | -0.00641937 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | -0.00641927 |
| CST7 | cystatin F (leukocystatin) | -0.00638093 |
| NELL2 | NEL-like 2 (chicken) | -0.00633698 |
| LIMA1 | LIM domain and actin binding 1 | -0.00633307 |
| AGT | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | -0.00632715 |
| MXRA7 | matrix-remodelling associated 7 | -0.00632449 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00632082 |
| CBX1 | chromobox homolog 1 | -0.00629487 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.00627619 |
| SLBP | stem-loop binding protein | -0.00626413 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | -0.00622523 |
| NPTN | neuroplastin | -0.00622497 |
| CHD7 | chromodomain helicase DNA binding protein 7 | -0.00617372 |
| MMP9 | matrix metallopeptidase 9 | -0.00616129 |
| CD3D | CD3d molecule, delta (CD3-TCR complex) | -0.00616104 |
| CGA | glycoprotein hormones, alpha polypeptide | -0.00614989 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.00610103 |
| EXPH5 | exophilin 5 | -0.00609753 |
| AOC3 | amine oxidase, copper containing 3 | -0.00606567 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.00605538 |
| SFTPB | surfactant protein B | -0.00603869 |
| PDZK1 | PDZ domain containing 1 | -0.00602835 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | -0.00602086 |
| RBPMS | RNA binding protein with multiple splicing | -0.00600862 |
| SOBP | sine oculis binding protein homolog (Drosophila) | -0.00600297 |
| RASGRP1 | RAS guanyl releasing protein 1 (calcium and DAG-regulated) | -0.0059962 |
| KIF5B | kinesin family member 5B | -0.00598838 |
| MYH10 | myosin, heavy chain 10, non-muscle | -0.00597053 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.00594247 |
| CPE | carboxypeptidase E | -0.00593492 |
| MAOA | monoamine oxidase A | -0.00593168 |
| F7 | coagulation factor VII (serum prothrombin conversion accelerator) | -0.00588737 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -0.0058705 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00582491 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00582173 |
| CSAD | cysteine sulfinic acid decarboxylase | -0.00581418 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00581418 |
| ABCD3 | ATP-binding cassette, sub-family D (ALD), member 3 | -0.00581188 |
| MCCC2 | methylcrotonoyl-CoA carboxylase 2 (beta) | -0.00578607 |
| STK39 | serine threonine kinase 39 | -0.00577269 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00576274 |
| USP12P1 | ubiquitin specific peptidase 12 pseudogene 1 | -0.00573035 |
| GOLM1 | golgi membrane protein 1 | -0.00572345 |
| PLA2G7 | phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma) | -0.00571309 |
| FOXF1 | forkhead box F1 | -0.00570356 |
| C1S | complement component 1, s subcomponent | -0.00569873 |
| CD8A | CD8a molecule | -0.0056971 |
| TRPM4 | transient receptor potential cation channel, subfamily M, member 4 | -0.00569235 |
| CDS1 | CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 | -0.00568876 |
| KPNB1 | karyopherin (importin) beta 1 | -0.00568116 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.0056748 |
| ID4 | inhibitor of DNA binding 4, dominant negative helix-loop-helix protein | -0.00567112 |
| MAP7 | microtubule-associated protein 7 | -0.0056454 |
| C3 | complement component 3 | -0.00563304 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.00563044 |
| HACD1 | 3-hydroxyacyl-CoA dehydratase 1 | -0.005628 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.00561562 |
| LYZ | lysozyme | -0.00561066 |
| CD81 | CD81 molecule | -0.00560413 |
| SELENBP1 | selenium binding protein 1 | -0.00558593 |
| HACD3 | 3-hydroxyacyl-CoA dehydratase 3 | -0.00558589 |
| ACSL5 | acyl-CoA synthetase long-chain family member 5 | -0.00551942 |
| PRDX2 | peroxiredoxin 2 | -0.00551273 |
| LONP2 | lon peptidase 2, peroxisomal | -0.00550924 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.00550419 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00549799 |
| HP | haptoglobin | -0.00549024 |
| METTL7A | methyltransferase like 7A | -0.00548725 |
| FHOD3 | formin homology 2 domain containing 3 | -0.00547719 |
| SNAI2 | snail family zinc finger 2 | -0.00546562 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.00544164 |
| SLC6A15 | solute carrier family 6 (neutral amino acid transporter), member 15 | -0.00543842 |
| PRKAR2B | protein kinase, cAMP-dependent, regulatory, type II, beta | -0.00543339 |
| TBC1D16 | TBC1 domain family, member 16 | -0.00542163 |
| WFDC1 | WAP four-disulfide core domain 1 | -0.00541988 |
| MLPH | melanophilin | -0.00541824 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.00541218 |
| ARMCX2 | armadillo repeat containing, X-linked 2 | -0.00540723 |
| MAGED1 | melanoma antigen family D1 | -0.00540547 |
| GTF2I | general transcription factor IIi | -0.00539585 |
| CDC42EP4 | CDC42 effector protein (Rho GTPase binding) 4 | -0.00538829 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.00538285 |
| GNAL | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type | -0.00538102 |
| FEM1B | fem-1 homolog b (C. elegans) | -0.00537008 |
| CELSR1 | cadherin, EGF LAG seven-pass G-type receptor 1 | -0.00535965 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00535754 |
| CLDN4 | claudin 4 | -0.00535108 |
| KPNA3 | karyopherin alpha 3 (importin alpha 4) | -0.00534681 |
| PTCH1 | patched 1 | -0.00534443 |
| TGM2 | transglutaminase 2 | -0.00534342 |
| SEPTIN9 | septin 9 | -0.00532331 |
| KIF14 | kinesin family member 14 | -0.0053098 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.0053 |
| TESC | tescalcin | -0.00529014 |
| WIPI1 | WD repeat domain, phosphoinositide interacting 1 | -0.00528247 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00528172 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.00527804 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | -0.00527103 |
| NIBAN1 | niban apoptosis regulator 1 | -0.00526613 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | -0.00526397 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.00525168 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00524469 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | -0.00523654 |
| SULT1A1 | sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1 | -0.00523532 |
| SLC24A3 | solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 | -0.00522743 |
| GPX2 | glutathione peroxidase 2 | -0.00522498 |
| KIAA0513 | KIAA0513 | -0.00522131 |
| FNBP1 | formin binding protein 1 | -0.00521903 |
| HLA-B | major histocompatibility complex, class I, B | -0.00517953 |
| RAPSN | receptor-associated protein of the synapse | -0.00514777 |
| PRKCZ | protein kinase C, zeta | -0.00513793 |
| CYP1A1 | cytochrome P450, family 1, subfamily A, polypeptide 1 | -0.00513757 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.00512691 |
| TBL1X | transducin (beta)-like 1X-linked | -0.00512465 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.00512297 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00510747 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | -0.0051024 |
| CHST2 | carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 | -0.00510132 |
| GNA11 | guanine nucleotide binding protein (G protein), alpha 11 (Gq class) | -0.00510077 |
| FABP5 | fatty acid binding protein 5 (psoriasis-associated) | -0.00510023 |
| CP | ceruloplasmin (ferroxidase) | -0.00509903 |
| NUSAP1 | nucleolar and spindle associated protein 1 | -0.00509475 |
| EHF | ets homologous factor | -0.00505019 |
| IL6ST | interleukin 6 signal transducer | -0.00504322 |
| PAX5 | paired box 5 | -0.0050427 |
| RREB1 | ras responsive element binding protein 1 | -0.00504193 |
| EIF1AX | eukaryotic translation initiation factor 1A, X-linked | -0.00503497 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | -0.00502384 |
| CTSH | cathepsin H | -0.00501095 |
| ADCY9 | adenylate cyclase 9 | -0.00499401 |
| CCR7 | chemokine (C-C motif) receptor 7 | -0.00499109 |
| CES1 | carboxylesterase 1 | -0.00498743 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.00498672 |
| SETBP1 | SET binding protein 1 | -0.00498519 |
| GZMK | granzyme K (granzyme 3; tryptase II) | -0.00497898 |
| THBS4 | thrombospondin 4 | -0.00497791 |
| AVPI1 | arginine vasopressin-induced 1 | -0.00497453 |
| SLC39A6 | solute carrier family 39 (zinc transporter), member 6 | -0.00497439 |
| CD27 | CD27 molecule | -0.0049704 |
| AMACR | alpha-methylacyl-CoA racemase | -0.00497001 |
| GEM | GTP binding protein overexpressed in skeletal muscle | -0.00496975 |
| SPG11 | spastic paraplegia 11 (autosomal recessive) | -0.00496784 |
| PPARG | peroxisome proliferator-activated receptor gamma | -0.00495289 |
| AKAP8L | A kinase (PRKA) anchor protein 8-like | -0.0049486 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.004941 |
| DBP | D site of albumin promoter (albumin D-box) binding protein | -0.00493043 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.00492058 |
| CALCA | calcitonin-related polypeptide alpha | -0.00491127 |
| SUB1 | SUB1 homolog (S. cerevisiae) | -0.00489269 |
| ADGRG2 | adhesion G protein-coupled receptor G2 | -0.00486364 |
| SNX7 | sorting nexin 7 | -0.00486277 |
| C4BPA | complement component 4 binding protein, alpha | -0.00486207 |
| TRAF5 | TNF receptor-associated factor 5 | -0.00485324 |
| EGR2 | early growth response 2 | -0.00483408 |
| NEFM | neurofilament, medium polypeptide | -0.00482839 |
| GSE1 | Gse1 coiled-coil protein | -0.00482262 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00480904 |
| VAMP1 | vesicle-associated membrane protein 1 (synaptobrevin 1) | -0.00480881 |
| SMTN | smoothelin | -0.00480051 |
