ENPP1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description ectonucleotide pyrophosphatase/phosphodiesterase 1|This gene is a member of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family. The encoded protein is a type II transmembrane glycoprotein comprising two identical disulfide-bonded subunits. This protein has broad specificity and cleaves a variety of substrates, including phosphodiester bonds of nucleotides and nucleotide sugars and pyrophosphate bonds of nucleotides and nucleotide sugars. This protein may function to hydrolyze nucleoside 5' triphosphates to their corresponding monophosphates and may also hydrolyze diadenosine polyphosphates. Mutations in this gene have been associated with 'idiopathic' infantile arterial calcification, ossification of the posterior longitudinal ligament of the spine (OPLL), and insulin resistance. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 5167)
External Link http://www.ncbi.nlm.nih.gov/gene/5167
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Genes

61 interacting proteins for ENPP1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABHD10 abhydrolase domain containing 10
ANXA1 annexin A1
ASPH aspartate beta-hydroxylase
BLOC1S5 biogenesis of lysosomal organelles complex-1, subunit 5, muted
C10ORF2 chromosome 10 open reading frame 2
CDC37 cell division cycle 37
CDC45 cell division cycle 45
CEP78 centrosomal protein 78kDa
CHEK1 checkpoint kinase 1
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
COX11 COX11 cytochrome c oxidase copper chaperone
CRNN cornulin
CTNND1 catenin (cadherin-associated protein), delta 1
DIP2B DIP2 disco-interacting protein 2 homolog B (Drosophila)
EMILIN3 elastin microfibril interfacer 3
EPDR1 ependymin related 1
EPPK1 epiplakin 1
GBAS glioblastoma amplified sequence
GLG1 golgi glycoprotein 1
GPC4 glypican 4
GTF3C1 general transcription factor IIIC, polypeptide 1, alpha 220kDa
GTF3C3 general transcription factor IIIC, polypeptide 3, 102kDa
HACD3 3-hydroxyacyl-CoA dehydratase 3
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit
HLA-H major histocompatibility complex, class I, H (pseudogene)
INA internexin neuronal intermediate filament protein, alpha
INSR insulin receptor
KEAP1 kelch-like ECH-associated protein 1
KRT4 keratin 4, type II
KRT73 keratin 73, type II
LAGE3 L antigen family, member 3
LLGL1 lethal giant larvae homolog 1 (Drosophila)
MARK2 MAP/microtubule affinity-regulating kinase 2
MICU1 mitochondrial calcium uptake 1
MICU2 mitochondrial calcium uptake 2
MRPL38 mitochondrial ribosomal protein L38
MRPS9 mitochondrial ribosomal protein S9
NBR1 neighbor of BRCA1 gene 1
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
NDUFS2 NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
NEFM neurofilament, medium polypeptide
NIPSNAP1 nipsnap homolog 1 (C. elegans)
NSUN4 NOP2/Sun domain family, member 4
OSBPL8 oxysterol binding protein-like 8
PARS2 prolyl-tRNA synthetase 2, mitochondrial (putative)
PLEC plectin
PRKCI protein kinase C, iota
RAD54L2 RAD54-like 2 (S. cerevisiae)
SARS2 seryl-tRNA synthetase 2, mitochondrial
SAV1 salvador family WW domain containing protein 1
SQSTM1 sequestosome 1
STK3 serine/threonine kinase 3
STK4 serine/threonine kinase 4
TCEAL2 transcription elongation factor A (SII)-like 2
TMEM160 transmembrane protein 160
TMLHE trimethyllysine hydroxylase, epsilon
TMX1 thioredoxin-related transmembrane protein 1
TRMT61B tRNA methyltransferase 61B
VIM vimentin
YME1L1 YME1-like 1 ATPase