EOMES Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description eomesodermin|This gene belongs to the TBR1 (T-box brain protein 1) sub-family of T-box genes that share the common DNA-binding T-box domain. The encoded protein is a transcription factor which is crucial for embryonic development of mesoderm and the central nervous system in vertebrates. The protein may also be necessary for the differentiation of effector CD8+ T cells which are involved in defense against viral infections. A similar gene disrupted in mice is shown to be essential during trophoblast development and gastrulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013] (NCBI Entrez Gene Database, 8320)
External Link https://ncbi.nlm.nih.gov/gene/8320
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Genes

499 genes differentially expressed following the EOMES gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 0.0213916
TM4SF1 transmembrane 4 L six family member 1 0.0141912
BIK BCL2-interacting killer (apoptosis-inducing) 0.013003
MAGEA3 melanoma antigen family A3 0.0128025
CXCL8 chemokine (C-X-C motif) ligand 8 0.0125532
KRT7 keratin 7, type II 0.0124019
GOLGA8A golgin A8 family, member A 0.0120423
ARL4A ADP-ribosylation factor-like 4A 0.011341
LAMC2 laminin, gamma 2 0.011266
HSPA1A heat shock 70kDa protein 1A 0.0112426
EIF5 eukaryotic translation initiation factor 5 0.0108465
AMIGO2 adhesion molecule with Ig-like domain 2 0.010689
ADO 2-aminoethanethiol (cysteamine) dioxygenase 0.0101932
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 0.0100923
PLAAT3 phospholipase A and acyltransferase 3 0.00999515
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.00990522
GALNT7 polypeptide N-acetylgalactosaminyltransferase 7 0.0098789
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog 0.00985378
S100A10 S100 calcium binding protein A10 0.00964116
CD163 CD163 molecule 0.0095769
KRT19 keratin 19, type I 0.00952024
ITGAV integrin, alpha V 0.00932716
ASNS asparagine synthetase (glutamine-hydrolyzing) 0.00928278
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) 0.0092165
DUSP10 dual specificity phosphatase 10 0.00920093
MRPS30 mitochondrial ribosomal protein S30 0.00896724
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00894105
CMAHP cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene 0.00885015
PFDN4 prefoldin subunit 4 0.00868542
LY96 lymphocyte antigen 96 0.00860221
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 0.00850153
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 0.00848908
CD14 CD14 molecule 0.00845723
AMH anti-Mullerian hormone 0.00824445
KLHL24 kelch-like family member 24 0.00816022
ARHGEF3 Rho guanine nucleotide exchange factor (GEF) 3 0.0081556
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding) 0.00813504
IMPA1 inositol(myo)-1(or 4)-monophosphatase 1 0.00811241
DEPTOR DEP domain containing MTOR-interacting protein 0.00796781
PIR pirin (iron-binding nuclear protein) 0.00795741
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.00789739
INPP4B inositol polyphosphate-4-phosphatase, type II, 105kDa 0.00786446
PMP22 peripheral myelin protein 22 0.00777212
TXLNA taxilin alpha 0.00775461
SLC30A1 solute carrier family 30 (zinc transporter), member 1 0.00767562
TIPARP TCDD-inducible poly(ADP-ribose) polymerase 0.00755842
TGFBI transforming growth factor, beta-induced, 68kDa 0.00749813
BHLHE41 basic helix-loop-helix family, member e41 0.0074762
RIN2 Ras and Rab interactor 2 0.00746681
MAPK6 mitogen-activated protein kinase 6 0.00744034
DPYD dihydropyrimidine dehydrogenase 0.00741578
DDX3X DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked 0.00739166
SPATS2L spermatogenesis associated, serine-rich 2-like 0.00736836
CTTN cortactin 0.00736168
LXN latexin 0.00736146
GNAS GNAS complex locus 0.00735611
RPS27L ribosomal protein S27-like 0.00735401
REEP5 receptor accessory protein 5 0.00734143
CCL18 chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) 0.00734024
MEX3C mex-3 RNA binding family member C 0.00733346
FN1 fibronectin 1 0.00733157
ANXA1 annexin A1 0.00731611
KYNU kynureninase 0.00730014
LTBP2 latent transforming growth factor beta binding protein 2 0.00728995
SLC20A1 solute carrier family 20 (phosphate transporter), member 1 0.00728727
CTSH cathepsin H 0.00722529
EGR2 early growth response 2 0.00722103
DCLK1 doublecortin-like kinase 1 0.00720912
DACT1 dishevelled-binding antagonist of beta-catenin 1 0.00717164
MXRA5 matrix-remodelling associated 5 0.00715103
ALOX5 arachidonate 5-lipoxygenase 0.00714902
C1QB complement component 1, q subcomponent, B chain 0.00710002
SC5D sterol-C5-desaturase 0.00709427
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 0.00707634
SMC1A structural maintenance of chromosomes 1A 0.00707048
SIK1 salt-inducible kinase 1 0.00707023
MAGEA12 melanoma antigen family A12 0.00704377
GCH1 GTP cyclohydrolase 1 0.00704186
LBH limb bud and heart development 0.00703293
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 0.00699476
ELF1 E74-like factor 1 (ets domain transcription factor) 0.00698736
XIC X chromosome inactivation center 0.00698475
THBS2 thrombospondin 2 0.00698077
LAMB3 laminin, beta 3 0.00697489
MAP7 microtubule-associated protein 7 0.00696031
GALNT3 polypeptide N-acetylgalactosaminyltransferase 3 0.00695508
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A 0.00695023
C8ORF4 chromosome 8 open reading frame 4 0.00694655
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 0.00692962
TACSTD2 tumor-associated calcium signal transducer 2 0.00691847
GIMAP6 GTPase, IMAP family member 6 0.00687092
ARMCX6 armadillo repeat containing, X-linked 6 0.0068692
KRT18 keratin 18, type I 0.00684868
ST6GALNAC2 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 0.00682775
EFNA1 ephrin-A1 0.00680902
DOCK9 dedicator of cytokinesis 9 0.00680407
CCL13 chemokine (C-C motif) ligand 13 0.00680273
CXCL13 chemokine (C-X-C motif) ligand 13 0.0067832
GSR glutathione reductase 0.00674997
AKR1C3 aldo-keto reductase family 1, member C3 0.00672627
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 0.00671518
FUCA1 fucosidase, alpha-L- 1, tissue 0.0067099
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A 0.00670623
PICALM phosphatidylinositol binding clathrin assembly protein 0.00669151
ISG20 interferon stimulated exonuclease gene 20kDa 0.0066705
SOX4 SRY (sex determining region Y)-box 4 0.00664367
PLXDC1 plexin domain containing 1 0.00659622
ARMCX3 armadillo repeat containing, X-linked 3 0.00657835
HSPA6 heat shock 70kDa protein 6 (HSP70B') 0.00653251
PLAU plasminogen activator, urokinase 0.00652944
VPS13B vacuolar protein sorting 13 homolog B (yeast) 0.00651946
GALC galactosylceramidase 0.00651213
MS4A4A membrane-spanning 4-domains, subfamily A, member 4A 0.0065016
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 0.00648371
EPS8 epidermal growth factor receptor pathway substrate 8 0.00647704
PSEN1 presenilin 1 0.00647678
HIST1H2AC histone cluster 1, H2ac 0.00646898
MORC4 MORC family CW-type zinc finger 4 0.00645593
BCL10 B-cell CLL/lymphoma 10 0.00644053
GPX2 glutathione peroxidase 2 0.00642683
PHLDA2 pleckstrin homology-like domain, family A, member 2 0.00640381
ITGB4 integrin, beta 4 0.00639572
HOXB7 homeobox B7 0.006374
GSN gelsolin 0.00636616
JUNB jun B proto-oncogene 0.00634427
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B 0.00633701
EMP1 epithelial membrane protein 1 0.00631347
POU2AF1 POU class 2 associating factor 1 0.00629
LIMK2 LIM domain kinase 2 0.00628369
TUFT1 tuftelin 1 0.00625792
KDM6A lysine (K)-specific demethylase 6A 0.0062555
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 0.00625188
PLTP phospholipid transfer protein 0.00624891
IFI27 interferon, alpha-inducible protein 27 0.0062378
RIT1 Ras-like without CAAX 1 0.00623649
CRIP1 cysteine-rich protein 1 (intestinal) 0.00623049
ZMAT3 zinc finger, matrin-type 3 0.00622448
SDCBP syndecan binding protein (syntenin) 0.0062148
WDR7 WD repeat domain 7 0.00620022
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) 0.00614975
STC1 stanniocalcin 1 0.00614853
STAMBP STAM binding protein 0.00614571
RNF6 ring finger protein (C3H2C3 type) 6 0.00613651
BAZ2B bromodomain adjacent to zinc finger domain, 2B 0.00613242
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 0.00613115
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 0.00611234
POLDIP2 polymerase (DNA-directed), delta interacting protein 2 0.00606685
SMAD2 SMAD family member 2 0.00605901
CHPT1 choline phosphotransferase 1 0.00605023
SH3TC1 SH3 domain and tetratricopeptide repeats 1 0.00604043
LMBRD1 LMBR1 domain containing 1 0.00603908
TPD52L1 tumor protein D52-like 1 0.00600954
RMDN1 regulator of microtubule dynamics 1 0.0059987
MIR22HG MIR22 host gene 0.00599108
SCG5 secretogranin V 0.00599025
PELO pelota homolog (Drosophila) 0.00597078
LEF1 lymphoid enhancer-binding factor 1 0.00596498
F13A1 coagulation factor XIII, A1 polypeptide 0.00594754
BRD2 bromodomain containing 2 0.00593291
SPATA20 spermatogenesis associated 20 0.00590974
PTHLH parathyroid hormone-like hormone 0.00590527
PLK2 polo-like kinase 2 0.00590458
UQCRH ubiquinol-cytochrome c reductase hinge protein 0.00589654
TSC22D1 TSC22 domain family, member 1 0.00588874
EGR1 early growth response 1 0.00588669
HDAC9 histone deacetylase 9 0.00587197
RAB9A RAB9A, member RAS oncogene family 0.00585614
ICA1 islet cell autoantigen 1, 69kDa 0.00585507
OSBPL1A oxysterol binding protein-like 1A 0.00585447
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae) 0.00585404
LUM lumican 0.00582654
CPD carboxypeptidase D 0.00581695
JMJD1C jumonji domain containing 1C 0.00579988
ANOS1 anosmin 1 0.00579899
TPK1 thiamin pyrophosphokinase 1 0.00579891
GBP2 guanylate binding protein 2, interferon-inducible 0.00579705
VSIG4 V-set and immunoglobulin domain containing 4 0.0057793
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.00575357
TAGLN2 transgelin 2 0.00575271
SLC7A7 solute carrier family 7 (amino acid transporter light chain, y+L system), member 7 0.00574817
SLC39A4 solute carrier family 39 (zinc transporter), member 4 0.00574596
GLRX glutaredoxin (thioltransferase) 0.00572714
NEU1 sialidase 1 (lysosomal sialidase) 0.00570181
SUSD6 sushi domain containing 6 0.00568264
AKAP8 A kinase (PRKA) anchor protein 8 0.00567147
SYNJ2 synaptojanin 2 0.00566363
TOB1 transducer of ERBB2, 1 0.00565708
TPRKB TP53RK binding protein 0.00564609
CXCL5 chemokine (C-X-C motif) ligand 5 0.00563301
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12 0.00561773
RFK riboflavin kinase 0.00561652
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta 0.00561634
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4 0.00560545
INHBA inhibin, beta A 0.00559976
ITM2A integral membrane protein 2A 0.00559659
HNMT histamine N-methyltransferase 0.00558827
GADD45A growth arrest and DNA-damage-inducible, alpha 0.00558414
HIST1H2BD histone cluster 1, H2bd 0.00557849
SLC19A2 solute carrier family 19 (thiamine transporter), member 2 0.00557201
TARS1 threonyl-tRNA synthetase 1 0.00556368
ATP5F1E ATP synthase F1 subunit epsilon 0.00554787
INPP1 inositol polyphosphate-1-phosphatase 0.0055475
AHR aryl hydrocarbon receptor 0.00554647
MOB4 MOB family member 4, phocein 0.00553999
C3ORF52 chromosome 3 open reading frame 52 0.00553946
SERPINI1 serpin peptidase inhibitor, clade I (neuroserpin), member 1 0.00552118
PDLIM4 PDZ and LIM domain 4 0.00551061
ASPH aspartate beta-hydroxylase 0.00550421
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 0.00549281
S100P S100 calcium binding protein P 0.00548698
IFT20 intraflagellar transport 20 0.00548658
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 0.00548059
ATF3 activating transcription factor 3 0.00546848
EPCAM epithelial cell adhesion molecule 0.00546447
TAX1BP3 Tax1 (human T-cell leukemia virus type I) binding protein 3 0.00546304
VAMP8 vesicle-associated membrane protein 8 0.00546191
TPST2 tyrosylprotein sulfotransferase 2 0.00546053
DUSP6 dual specificity phosphatase 6 0.00545442
ADRB2 adrenoceptor beta 2, surface 0.00543022
DCN decorin 0.0054267
IGF1R insulin-like growth factor 1 receptor 0.00542411
OFD1 oral-facial-digital syndrome 1 0.00542176
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4 0.00541432
SLC38A6 solute carrier family 38, member 6 0.00541404
RBM7 RNA binding motif protein 7 0.00539244
DCTN6 dynactin 6 0.00538719
MGAT2 mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 0.00538107
MYO1B myosin IB 0.00537787
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon 0.00537265
CHMP2B charged multivesicular body protein 2B 0.00537187
TWF1 twinfilin actin binding protein 1 0.00535509
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 0.00535493
USP9X ubiquitin specific peptidase 9, X-linked 0.00533798
VAMP4 vesicle-associated membrane protein 4 0.00531967
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3 0.00531837
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.00531704
RGS2 regulator of G-protein signaling 2 0.00531684
WSB2 WD repeat and SOCS box containing 2 0.00531353
EVI2A ecotropic viral integration site 2A 0.00530291
LY75 lymphocyte antigen 75 0.00527909
PHYH phytanoyl-CoA 2-hydroxylase 0.00527183
ODC1 ornithine decarboxylase 1 0.00526998
CKS2 CDC28 protein kinase regulatory subunit 2 0.00526969
GPATCH2 G patch domain containing 2 0.00526237
PERP PERP, TP53 apoptosis effector 0.0052369
PDCD10 programmed cell death 10 0.00523467
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase) 0.0052248
SERPINE1 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 0.00522376
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 0.00522342

decreased expression

Symbol Name Standardized Value
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.0152312
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 -0.0137311
EIF1AY eukaryotic translation initiation factor 1A, Y-linked -0.0134304
CRABP2 cellular retinoic acid binding protein 2 -0.0118153
FXYD6 FXYD domain containing ion transport regulator 6 -0.0109238
FGFR3 fibroblast growth factor receptor 3 -0.0107754
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 -0.0105942
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 -0.0101296
SFRP1 secreted frizzled-related protein 1 -0.0100256
MEIS2 Meis homeobox 2 -0.00924655
KDM5D lysine (K)-specific demethylase 5D -0.00887679
ARG1 arginase 1 -0.00869979
SPARCL1 SPARC-like 1 (hevin) -0.00851316
ADH1B alcohol dehydrogenase 1B (class I), beta polypeptide -0.00848716
IFITM2 interferon induced transmembrane protein 2 -0.00847701
BANK1 B-cell scaffold protein with ankyrin repeats 1 -0.00836214
CXCL14 chemokine (C-X-C motif) ligand 14 -0.00833894
BIRC5 baculoviral IAP repeat containing 5 -0.0082583
AURKB aurora kinase B -0.00810675
CXCL12 chemokine (C-X-C motif) ligand 12 -0.00809138
SNAP25 synaptosomal-associated protein, 25kDa -0.00806354
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -0.00804774
GLO1 glyoxalase I -0.0080474
FAIM Fas apoptotic inhibitory molecule -0.00802231
PDZK1 PDZ domain containing 1 -0.0080008
IDH2 isocitrate dehydrogenase 2 (NADP+), mitochondrial -0.00799559
STK10 serine/threonine kinase 10 -0.00796267
AZGP1 alpha-2-glycoprotein 1, zinc-binding -0.00792356
ASF1B anti-silencing function 1B histone chaperone -0.00791058
LIG1 ligase I, DNA, ATP-dependent -0.00788274
FOXM1 forkhead box M1 -0.00777784
PRKACA protein kinase, cAMP-dependent, catalytic, alpha -0.00776577
FGFR1 fibroblast growth factor receptor 1 -0.00775281
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) -0.00772601
SDC1 syndecan 1 -0.00770197
IFITM1 interferon induced transmembrane protein 1 -0.00770099
CRABP1 cellular retinoic acid binding protein 1 -0.00769744
C7 complement component 7 -0.00759366
FUS FUS RNA binding protein -0.00758546
PIMREG PICALM interacting mitotic regulator -0.00753013
KRT1 keratin 1, type II -0.00752414
ASCL1 achaete-scute family bHLH transcription factor 1 -0.00748619
IFRD2 interferon-related developmental regulator 2 -0.00742857
DES desmin -0.00738908
CCNF cyclin F -0.0073746
FASN fatty acid synthase -0.00733254
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5 -0.00726931
GMPR guanosine monophosphate reductase -0.00726075
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2 -0.00726069
DLK1 delta-like 1 homolog (Drosophila) -0.00724919
P3H2 prolyl 3-hydroxylase 2 -0.00723704
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain -0.00720074
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor -0.00718121
FHL1 four and a half LIM domains 1 -0.00711871
HBB hemoglobin, beta -0.00691255
KRT2 keratin 2, type II -0.00688412
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) -0.0068819
KIF20A kinesin family member 20A -0.0068542
SLC2A4RG SLC2A4 regulator -0.00679858
DSG1 desmoglein 1 -0.00675145
IFITM3 interferon induced transmembrane protein 3 -0.00671463
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.00670665
CDC20 cell division cycle 20 -0.00662101
ACADVL acyl-CoA dehydrogenase, very long chain -0.00660741
RAPSN receptor-associated protein of the synapse -0.00659859
ANXA6 annexin A6 -0.00654809
SIRT3 sirtuin 3 -0.00654066
OLFM1 olfactomedin 1 -0.00653976
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2 -0.00653973
TROAP trophinin associated protein -0.00653214
TTC39A tetratricopeptide repeat domain 39A -0.00650378
BCHE butyrylcholinesterase -0.00649307
RNASEH2A ribonuclease H2, subunit A -0.00646708
SPINK5 serine peptidase inhibitor, Kazal type 5 -0.00646449
FBXO11 F-box protein 11 -0.00645242
MBOAT7 membrane bound O-acyltransferase domain containing 7 -0.00645
MCM2 minichromosome maintenance complex component 2 -0.00644122
S100A7 S100 calcium binding protein A7 -0.00640766
TMED9 transmembrane emp24 protein transport domain containing 9 -0.00640536
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) -0.00637637
DDX3Y DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked -0.00635054
NRGN neurogranin (protein kinase C substrate, RC3) -0.00629613
LTF lactotransferrin -0.00628297
DCXR dicarbonyl/L-xylulose reductase -0.00627694
COL1A2 collagen, type I, alpha 2 -0.00625876
PTCH1 patched 1 -0.00625476
CAV1 caveolin 1, caveolae protein, 22kDa -0.0061992
PRG2 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) -0.00616893
OPHN1 oligophrenin 1 -0.00616033
DENND2B DENN domain containing 2B -0.00614609
ISYNA1 inositol-3-phosphate synthase 1 -0.00613132
CDCA3 cell division cycle associated 3 -0.0061049
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) -0.00609448
LMNB2 lamin B2 -0.0060938
TLCD3A TLC domain containing 3A -0.00606527
SCGB1D2 secretoglobin, family 1D, member 2 -0.00605986
ALDOA aldolase A, fructose-bisphosphate -0.00605702
EMP2 epithelial membrane protein 2 -0.00604938
PEG3 paternally expressed 3 -0.00603225
ACAT2 acetyl-CoA acetyltransferase 2 -0.00602749
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) -0.00602409
CRYBG1 crystallin beta-gamma domain containing 1 -0.00601477
EPHB4 EPH receptor B4 -0.00600236
CTDNEP1 CTD nuclear envelope phosphatase 1 -0.00600162
TGFB1 transforming growth factor, beta 1 -0.00597685
H1-10 H1.10 linker histone -0.00597402
NCAPD3 non-SMC condensin II complex, subunit D3 -0.00593443
SLC35E2B solute carrier family 35, member E2B -0.00592921
PXMP2 peroxisomal membrane protein 2, 22kDa -0.00591335
TMEM38B transmembrane protein 38B -0.00590682
NBEAL2 neurobeachin-like 2 -0.00588027
BEX1 brain expressed, X-linked 1 -0.00582617
CEACAM8 carcinoembryonic antigen-related cell adhesion molecule 8 -0.00582388
CIT citron rho-interacting serine/threonine kinase -0.00581946
TYRO3 TYRO3 protein tyrosine kinase -0.00581036
HNRNPA3 heterogeneous nuclear ribonucleoprotein A3 -0.00581026
RXRA retinoid X receptor, alpha -0.00580595
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) -0.0058045
KLK5 kallikrein-related peptidase 5 -0.00580018
PRRC2A proline-rich coiled-coil 2A -0.00579059
CES1 carboxylesterase 1 -0.00577775
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.00577501
COL4A3 collagen, type IV, alpha 3 (Goodpasture antigen) -0.00576152
TARP TCR gamma alternate reading frame protein -0.00575642
CALML5 calmodulin-like 5 -0.00574184
PPP1R1A protein phosphatase 1, regulatory (inhibitor) subunit 1A -0.00574106
LOR loricrin -0.00573529
TNNT1 troponin T type 1 (skeletal, slow) -0.00572109
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 -0.00571783
DEFA4 defensin, alpha 4, corticostatin -0.00571664
HELLS helicase, lymphoid-specific -0.00570042
TECR trans-2,3-enoyl-CoA reductase -0.00569941
KLHDC3 kelch domain containing 3 -0.0056875
DCHS1 dachsous cadherin-related 1 -0.0056644
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) -0.00566369
PLEKHO1 pleckstrin homology domain containing, family O member 1 -0.00565644
FHOD3 formin homology 2 domain containing 3 -0.00565268
KAZN kazrin, periplakin interacting protein -0.005648
CLIC3 chloride intracellular channel 3 -0.00563918
MMP9 matrix metallopeptidase 9 -0.00560115
CRCT1 cysteine-rich C-terminal 1 -0.00558706
GINS1 GINS complex subunit 1 (Psf1 homolog) -0.00558357
PSRC1 proline/serine-rich coiled-coil 1 -0.00556955
SNRPA small nuclear ribonucleoprotein polypeptide A -0.00556452
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 -0.00554863
SLURP1 secreted LY6/PLAUR domain containing 1 -0.00553884
PXDN peroxidasin -0.00553551
NME4 NME/NM23 nucleoside diphosphate kinase 4 -0.00553157
DIRAS3 DIRAS family, GTP-binding RAS-like 3 -0.00550133
NPTX2 neuronal pentraxin II -0.00549956
TMSB15A thymosin beta 15a -0.00549797
LCP1 lymphocyte cytosolic protein 1 (L-plastin) -0.00548796
TNNI2 troponin I type 2 (skeletal, fast) -0.00548327
HYOU1 hypoxia up-regulated 1 -0.00546702
PLEK pleckstrin -0.00545682
CAMP cathelicidin antimicrobial peptide -0.00545339
PTOV1 prostate tumor overexpressed 1 -0.00543857
RUVBL1 RuvB-like AAA ATPase 1 -0.00542541
SERPINB8 serpin peptidase inhibitor, clade B (ovalbumin), member 8 -0.0054151
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 -0.00541006
BPI bactericidal/permeability-increasing protein -0.00540849
IPO9 importin 9 -0.00540777
TK1 thymidine kinase 1, soluble -0.00538988
GSTA1 glutathione S-transferase alpha 1 -0.00535389
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) -0.00535259
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) -0.0053492
NKG7 natural killer cell granule protein 7 -0.00534626
SHMT1 serine hydroxymethyltransferase 1 (soluble) -0.00533568
TELO2 telomere maintenance 2 -0.0053321
PTGER3 prostaglandin E receptor 3 (subtype EP3) -0.0053308
NEIL3 nei endonuclease VIII-like 3 (E. coli) -0.00532865
P4HB prolyl 4-hydroxylase, beta polypeptide -0.00532862
FABP7 fatty acid binding protein 7, brain -0.00532832
GTSE1 G-2 and S-phase expressed 1 -0.00532666
CHKB choline kinase beta -0.00530378
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -0.00530341
ACP3 acid phosphatase 3 -0.00530203
AOX1 aldehyde oxidase 1 -0.00528442
TRIP6 thyroid hormone receptor interactor 6 -0.0052824
RNF167 ring finger protein 167 -0.00528192
OASL 2'-5'-oligoadenylate synthetase-like -0.00527518
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -0.00527369
GPC1 glypican 1 -0.00527225
EEF1A2 eukaryotic translation elongation factor 1 alpha 2 -0.00526932
RAB3B RAB3B, member RAS oncogene family -0.00526833
LAMP5 lysosomal-associated membrane protein family, member 5 -0.00526798
HPD 4-hydroxyphenylpyruvate dioxygenase -0.00525205
CA2 carbonic anhydrase II -0.00524657
NSD2 nuclear receptor binding SET domain protein 2 -0.00523233
DHCR24 24-dehydrocholesterol reductase -0.0052268
CCL5 chemokine (C-C motif) ligand 5 -0.00522507
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2 -0.00522259
NT5DC2 5'-nucleotidase domain containing 2 -0.00521708
BCKDK branched chain ketoacid dehydrogenase kinase -0.00520402
PGC progastricsin (pepsinogen C) -0.00518896
SLC25A11 solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 -0.00516732
COQ2 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase -0.00515966
TULP3 tubby like protein 3 -0.00514958
ECI1 enoyl-CoA delta isomerase 1 -0.00514713
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) -0.00514134
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type -0.0051296
SUB1 SUB1 homolog (S. cerevisiae) -0.0051095
TP53 tumor protein p53 -0.0051052
OIP5 Opa interacting protein 5 -0.00507084
NR5A1 nuclear receptor subfamily 5, group A, member 1 -0.00507028
PAH phenylalanine hydroxylase -0.00506692
AKR7A3 aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) -0.00506421
CD300A CD300a molecule -0.00506299
B4GALT2 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2 -0.0050551
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa -0.00503
CDCA4 cell division cycle associated 4 -0.00502731
SPARC secreted protein, acidic, cysteine-rich (osteonectin) -0.00502626
ECH1 enoyl CoA hydratase 1, peroxisomal -0.00501105
KIF15 kinesin family member 15 -0.00500514
ICMT isoprenylcysteine carboxyl methyltransferase -0.004994
FCN1 ficolin (collagen/fibrinogen domain containing) 1 -0.00498832
CSNK2B casein kinase 2, beta polypeptide -0.0049811
LSP1 lymphocyte-specific protein 1 -0.00497165
AGTR1 angiotensin II receptor, type 1 -0.00496208
FBL fibrillarin -0.00495064
TCAP titin-cap -0.00494705
SEPTIN10 septin 10 -0.00494694
PLIN2 perilipin 2 -0.00494536
FXYD2 FXYD domain containing ion transport regulator 2 -0.00494367
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 -0.00493322
DSC1 desmocollin 1 -0.00492548
ILF3 interleukin enhancer binding factor 3, 90kDa -0.00490322
PEX6 peroxisomal biogenesis factor 6 -0.00489987
IRF8 interferon regulatory factor 8 -0.00489925
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 -0.00489913
WRAP53 WD repeat containing, antisense to TP53 -0.0048978
CARHSP1 calcium regulated heat stable protein 1, 24kDa -0.00489162
GFRA1 GDNF family receptor alpha 1 -0.00488974
APMAP adipocyte plasma membrane associated protein -0.00488721
DCTD dCMP deaminase -0.00488362
AQP9 aquaporin 9 -0.0048779
CLDN3 claudin 3 -0.00487104
PDE4B phosphodiesterase 4B, cAMP-specific -0.00486812
FSTL1 follistatin-like 1 -0.00486486
CRYM crystallin, mu -0.00485018
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 -0.00484326
AMPD1 adenosine monophosphate deaminase 1 -0.00483861
PGAM1 phosphoglycerate mutase 1 (brain) -0.00483742
METTL7A methyltransferase like 7A -0.00482744
RAD54B RAD54 homolog B (S. cerevisiae) -0.00482396
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -0.00481208
SNCA synuclein, alpha (non A4 component of amyloid precursor) -0.00480682
SLC22A17 solute carrier family 22, member 17 -0.00480379
GYPC glycophorin C (Gerbich blood group) -0.00479967
SF3B3 splicing factor 3b, subunit 3, 130kDa -0.00478021