| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | E1A binding protein p300|This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2033) |
| External Link | https://ncbi.nlm.nih.gov/gene/2033 |
| Similar Terms | |
| Downloads & Tools |
498 genes differentially expressed following the EP300 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.0121129 |
| PPP1R13B | protein phosphatase 1, regulatory subunit 13B | 0.0115699 |
| ARPP19 | cAMP-regulated phosphoprotein, 19kDa | 0.00914011 |
| NXN | nucleoredoxin | 0.00902383 |
| CRLF1 | cytokine receptor-like factor 1 | 0.00878617 |
| H1-2 | H1.2 linker histone, cluster member | 0.00861035 |
| TMEM14B | transmembrane protein 14B | 0.00791521 |
| HOPX | HOP homeobox | 0.00770202 |
| PCLAF | PCNA clamp associated factor | 0.00767936 |
| RGCC | regulator of cell cycle | 0.00766674 |
| YBX3 | Y box binding protein 3 | 0.00766242 |
| TMEM126B | transmembrane protein 126B | 0.00765375 |
| COL3A1 | collagen, type III, alpha 1 | 0.00757872 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.00751017 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00727347 |
| SST | somatostatin | 0.00726645 |
| NRGN | neurogranin (protein kinase C substrate, RC3) | 0.00720153 |
| SPARCL1 | SPARC-like 1 (hevin) | 0.00710117 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.00706485 |
| LMO3 | LIM domain only 3 (rhombotin-like 2) | 0.0069858 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.00694068 |
| POLR1D | polymerase (RNA) I polypeptide D, 16kDa | 0.00692207 |
| FRZB | frizzled-related protein | 0.00691902 |
| NVL | nuclear VCP-like | 0.00689485 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.00682768 |
| ATP5MJ | ATP synthase membrane subunit j | 0.00668044 |
| CCDC92 | coiled-coil domain containing 92 | 0.00651704 |
| MALL | mal, T-cell differentiation protein-like | 0.00644928 |
| CDKN3 | cyclin-dependent kinase inhibitor 3 | 0.00643704 |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase | 0.00641358 |
| MSLN | mesothelin | 0.00639493 |
| MAD2L1 | MAD2 mitotic arrest deficient-like 1 (yeast) | 0.00638998 |
| MRPL13 | mitochondrial ribosomal protein L13 | 0.00637082 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | 0.00635049 |
| CNIH4 | cornichon family AMPA receptor auxiliary protein 4 | 0.00634809 |
| IGFBP2 | insulin-like growth factor binding protein 2, 36kDa | 0.00633753 |
| E2F2 | E2F transcription factor 2 | 0.00625955 |
| ATAD2 | ATPase family, AAA domain containing 2 | 0.00625504 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 | 0.00618254 |
| NDUFB5 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5, 16kDa | 0.00612567 |
| HOXD1 | homeobox D1 | 0.00609386 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00601883 |
| SELENOT | selenoprotein T | 0.00600156 |
| METTL5 | methyltransferase like 5 | 0.00598259 |
| RTN2 | reticulon 2 | 0.00595435 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 | 0.00595286 |
| MRS2 | MRS2 magnesium transporter | 0.00594207 |
| MAOA | monoamine oxidase A | 0.00593418 |
| SFTPB | surfactant protein B | 0.00586413 |
| WT1 | Wilms tumor 1 | 0.00583833 |
| TTN | titin | 0.00579789 |
| MCM6 | minichromosome maintenance complex component 6 | 0.00579767 |
| PCP4 | Purkinje cell protein 4 | 0.00576493 |
| ACOT13 | acyl-CoA thioesterase 13 | 0.00572244 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00571704 |
| SELENOW | selenoprotein W | 0.00569018 |
| TDP2 | tyrosyl-DNA phosphodiesterase 2 | 0.00568563 |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 | 0.00564766 |
| RPS5 | ribosomal protein S5 | 0.00563562 |
| HMGB3 | high mobility group box 3 | 0.00561819 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | 0.00560879 |
| TRAM1 | translocation associated membrane protein 1 | 0.00557603 |
| MEIS2 | Meis homeobox 2 | 0.00556417 |
| SERPINB8 | serpin peptidase inhibitor, clade B (ovalbumin), member 8 | 0.00553792 |
| WASF1 | WAS protein family, member 1 | 0.00551399 |
| ATG5 | autophagy related 5 | 0.0055037 |
| PTTG1 | pituitary tumor-transforming 1 | 0.0054961 |
| LRRC17 | leucine rich repeat containing 17 | 0.00548983 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.00548401 |
| POLR2L | polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa | 0.00547499 |
| RAD51C | RAD51 paralog C | 0.00547145 |
| RPA3 | replication protein A3, 14kDa | 0.00545326 |
| FOLR1 | folate receptor 1 (adult) | 0.00543156 |
| CLEC2B | C-type lectin domain family 2, member B | 0.00542484 |
| ID3 | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 0.0054134 |
| GPR88 | G protein-coupled receptor 88 | 0.00540519 |
| CLIC5 | chloride intracellular channel 5 | 0.00539042 |
| ODC1 | ornithine decarboxylase 1 | 0.00538861 |
| PTK7 | protein tyrosine kinase 7 (inactive) | 0.00536071 |
| CCK | cholecystokinin | 0.00531758 |
| HTRA1 | HtrA serine peptidase 1 | 0.00530766 |
| CNPY3 | canopy FGF signaling regulator 3 | 0.00530247 |
| KLK5 | kallikrein-related peptidase 5 | 0.00530028 |
| CDC20 | cell division cycle 20 | 0.0052933 |
| BPHL | biphenyl hydrolase-like (serine hydrolase) | 0.00528649 |
| NINJ2 | ninjurin 2 | 0.00527934 |
| BAG2 | BCL2-associated athanogene 2 | 0.00527641 |
| SAR1B | secretion associated, Ras related GTPase 1B | 0.00526046 |
| ELANE | elastase, neutrophil expressed | 0.00525163 |
| COMMD8 | COMM domain containing 8 | 0.00524853 |
| DCK | deoxycytidine kinase | 0.00524246 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.0052385 |
| CD34 | CD34 molecule | 0.00523535 |
| RYR1 | ryanodine receptor 1 (skeletal) | 0.00523203 |
| C1QBP | complement component 1, q subcomponent binding protein | 0.00522752 |
| PDGFC | platelet derived growth factor C | 0.00521807 |
| CYBRD1 | cytochrome b reductase 1 | 0.00521598 |
| COX7A2L | cytochrome c oxidase subunit VIIa polypeptide 2 like | 0.00519846 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00519154 |
| CALML5 | calmodulin-like 5 | 0.0051877 |
| TRAPPC2L | trafficking protein particle complex 2-like | 0.00517745 |
| MTX2 | metaxin 2 | 0.00517459 |
| MMP11 | matrix metallopeptidase 11 | 0.00517071 |
| ATP5MG | ATP synthase membrane subunit g | 0.0051695 |
| MRPS16 | mitochondrial ribosomal protein S16 | 0.00516607 |
| ADGRF5 | adhesion G protein-coupled receptor F5 | 0.00514907 |
| PECR | peroxisomal trans-2-enoyl-CoA reductase | 0.00513942 |
| RPL14 | ribosomal protein L14 | 0.00512685 |
| TMEM70 | transmembrane protein 70 | 0.00512672 |
| MOB4 | MOB family member 4, phocein | 0.00512236 |
| HAT1 | histone acetyltransferase 1 | 0.00511492 |
| NOTCH1 | notch 1 | 0.00511358 |
| NTAQ1 | N-terminal glutamine amidase 1 | 0.00511123 |
| NIPSNAP2 | nipsnap homolog 2 | 0.00510201 |
| CCNB2 | cyclin B2 | 0.00509966 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.0050944 |
| QRSL1 | glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 | 0.00508807 |
| ECI2 | enoyl-CoA delta isomerase 2 | 0.00508213 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.00506861 |
| MEF2C | myocyte enhancer factor 2C | 0.0050515 |
| ENY2 | enhancer of yellow 2 homolog (Drosophila) | 0.0050261 |
| TMEM50B | transmembrane protein 50B | 0.00502428 |
| LYRM4 | LYR motif containing 4 | 0.00500853 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.00500358 |
| ZNF277 | zinc finger protein 277 | 0.00500111 |
| DNM1L | dynamin 1-like | 0.00500067 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.00498667 |
| SNAP29 | synaptosomal-associated protein, 29kDa | 0.00498083 |
| PTP4A3 | protein tyrosine phosphatase type IVA, member 3 | 0.00497889 |
| TSPAN12 | tetraspanin 12 | 0.0049762 |
| UQCR11 | ubiquinol-cytochrome c reductase, complex III subunit XI | 0.00495933 |
| HIST1H2BH | histone cluster 1, H2bh | 0.00495252 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 0.00494741 |
| SUMO1 | small ubiquitin-like modifier 1 | 0.00493822 |
| ENC1 | ectodermal-neural cortex 1 (with BTB domain) | 0.0049197 |
| GNAS | GNAS complex locus | 0.00490863 |
| MRPL9 | mitochondrial ribosomal protein L9 | 0.00490245 |
| KLHL23 | kelch-like family member 23 | 0.00490168 |
| GINS1 | GINS complex subunit 1 (Psf1 homolog) | 0.0049016 |
| RSL24D1 | ribosomal L24 domain containing 1 | 0.00489174 |
| SNRPD2 | small nuclear ribonucleoprotein D2 polypeptide 16.5kDa | 0.00487166 |
| MRPL48 | mitochondrial ribosomal protein L48 | 0.00486333 |
| FZD5 | frizzled class receptor 5 | 0.0048575 |
| IDI1 | isopentenyl-diphosphate delta isomerase 1 | 0.0048504 |
| TNNI1 | troponin I type 1 (skeletal, slow) | 0.00483575 |
| GNG10 | guanine nucleotide binding protein (G protein), gamma 10 | 0.00482159 |
| TGFB1 | transforming growth factor, beta 1 | 0.00481733 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | 0.00480581 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00480223 |
| HEBP2 | heme binding protein 2 | 0.0047979 |
| SPTSSA | serine palmitoyltransferase, small subunit A | 0.00479233 |
| SUCLG2 | succinate-CoA ligase, GDP-forming, beta subunit | 0.00479226 |
| PLN | phospholamban | 0.00478764 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.00478489 |
| NOP10 | NOP10 ribonucleoprotein | 0.00477642 |
| MRPL57 | mitochondrial ribosomal protein L57 | 0.00477625 |
| MED21 | mediator complex subunit 21 | 0.00477231 |
| CNIH1 | cornichon family AMPA receptor auxiliary protein 1 | 0.00476411 |
| ORC4 | origin recognition complex, subunit 4 | 0.00474958 |
| CACNA1A | calcium channel, voltage-dependent, P/Q type, alpha 1A subunit | 0.0047493 |
| SNAI2 | snail family zinc finger 2 | 0.00473697 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.00473091 |
| RBX1 | ring-box 1, E3 ubiquitin protein ligase | 0.00472205 |
| TSPO | translocator protein (18kDa) | 0.00472008 |
| SQLE | squalene epoxidase | 0.00469846 |
| PPA2 | pyrophosphatase (inorganic) 2 | 0.00469769 |
| PHYH | phytanoyl-CoA 2-hydroxylase | 0.00469424 |
| VSIG4 | V-set and immunoglobulin domain containing 4 | 0.00469312 |
| SLC38A6 | solute carrier family 38, member 6 | 0.00468426 |
| SLC25A6 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6 | 0.00467246 |
| TNNT3 | troponin T type 3 (skeletal, fast) | 0.00467079 |
| TM7SF2 | transmembrane 7 superfamily member 2 | 0.00465325 |
| BTG3 | BTG family, member 3 | 0.00464772 |
| PRDX3 | peroxiredoxin 3 | 0.00464235 |
| AQP4 | aquaporin 4 | 0.00463887 |
| HIST1H2AE | histone cluster 1, H2ae | 0.0046365 |
| SAC3D1 | SAC3 domain containing 1 | 0.00463289 |
| PRTN3 | proteinase 3 | 0.00462917 |
| TK1 | thymidine kinase 1, soluble | 0.00461413 |
| E2F5 | E2F transcription factor 5, p130-binding | 0.00460132 |
| EPHA4 | EPH receptor A4 | 0.00458843 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.00458615 |
| MAP7 | microtubule-associated protein 7 | 0.00458458 |
| KLHL41 | kelch-like family member 41 | 0.00458063 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | 0.004578 |
| NFU1 | NFU1 iron-sulfur cluster scaffold | 0.00457159 |
| NDUFB6 | NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa | 0.00456925 |
| MYH2 | myosin, heavy chain 2, skeletal muscle, adult | 0.0045677 |
| MAPK1 | mitogen-activated protein kinase 1 | 0.00456307 |
| TIMM9 | translocase of inner mitochondrial membrane 9 homolog (yeast) | 0.00455567 |
| PFN2 | profilin 2 | 0.00454922 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.00454449 |
| MRPL35 | mitochondrial ribosomal protein L35 | 0.00454152 |
| LY6H | lymphocyte antigen 6 complex, locus H | 0.00453594 |
| TPM3 | tropomyosin 3 | 0.00452928 |
| MOCS2 | molybdenum cofactor synthesis 2 | 0.00452272 |
| SFTPD | surfactant protein D | 0.00451888 |
| EEF1B2 | eukaryotic translation elongation factor 1 beta 2 | 0.00451279 |
| EPHX1 | epoxide hydrolase 1, microsomal (xenobiotic) | 0.00451195 |
| DDN | dendrin | 0.00451024 |
| SDHAF3 | succinate dehydrogenase complex assembly factor 3 | 0.00450832 |
| MYL2 | myosin, light chain 2, regulatory, cardiac, slow | 0.00450659 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.00450642 |
| FASTKD3 | FAST kinase domains 3 | 0.00449632 |
| RPL10A | ribosomal protein L10a | 0.00448433 |
| TPST2 | tyrosylprotein sulfotransferase 2 | 0.00448136 |
| GTF2A2 | general transcription factor IIA, 2, 12kDa | 0.00447898 |
| ATP5F1C | ATP synthase F1 subunit gamma | 0.00447593 |
| METRN | meteorin, glial cell differentiation regulator | 0.00447369 |
| ITM2C | integral membrane protein 2C | 0.00446976 |
| SDC1 | syndecan 1 | 0.00444876 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0044343 |
| SNX3 | sorting nexin 3 | 0.00442432 |
| MYBPC2 | myosin binding protein C, fast type | 0.00441659 |
| GLUL | glutamate-ammonia ligase | 0.00441619 |
| CALD1 | caldesmon 1 | 0.004416 |
| DLX5 | distal-less homeobox 5 | 0.00441529 |
| TPRKB | TP53RK binding protein | 0.00440784 |
| MRPL11 | mitochondrial ribosomal protein L11 | 0.00439521 |
| TCF21 | transcription factor 21 | 0.00439132 |
| RAPSN | receptor-associated protein of the synapse | 0.00437916 |
| ZMYM5 | zinc finger, MYM-type 5 | 0.00437863 |
| PTP4A1 | protein tyrosine phosphatase type IVA, member 1 | 0.00437329 |
| NEK2 | NIMA-related kinase 2 | 0.00437307 |
| MPO | myeloperoxidase | 0.00436616 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00436569 |
| RGS2 | regulator of G-protein signaling 2 | 0.00435619 |
| COX7B | cytochrome c oxidase subunit VIIb | 0.00435474 |
| ORC1 | origin recognition complex, subunit 1 | 0.00433757 |
| RNF115 | ring finger protein 115 | 0.0043364 |
| CHRNA1 | cholinergic receptor, nicotinic, alpha 1 (muscle) | 0.00433299 |
| PSMA3 | proteasome (prosome, macropain) subunit, alpha type, 3 | 0.00432591 |
| GFAP | glial fibrillary acidic protein | 0.00431312 |
| CORO1A | coronin, actin binding protein, 1A | 0.00431306 |
| MSMO1 | methylsterol monooxygenase 1 | 0.00430675 |
| NUP37 | nucleoporin 37kDa | 0.00430033 |
| ALOX15B | arachidonate 15-lipoxygenase, type B | 0.00429573 |
| TSPAN6 | tetraspanin 6 | 0.00428935 |
| CCNA2 | cyclin A2 | 0.00428825 |
| CKM | creatine kinase, muscle | 0.00428744 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 0.00428696 |
| CHN1 | chimerin 1 | 0.00428591 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | 0.00427975 |
| HINT1 | histidine triad nucleotide binding protein 1 | 0.00427885 |
| ZDHHC4 | zinc finger, DHHC-type containing 4 | 0.00426928 |
| MYOZ2 | myozenin 2 | 0.00426899 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.00426513 |
| IPO13 | importin 13 | 0.0042595 |
| CLNS1A | chloride channel, nucleotide-sensitive, 1A | 0.00425936 |
| EVI2A | ecotropic viral integration site 2A | 0.00425301 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SSBP2 | single-stranded DNA binding protein 2 | -0.0168966 |
| TFF1 | trefoil factor 1 | -0.0156248 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.0133565 |
| PROM1 | prominin 1 | -0.012639 |
| EGR2 | early growth response 2 | -0.0123783 |
| GATA3 | GATA binding protein 3 | -0.0111283 |
| NTRK2 | neurotrophic tyrosine kinase, receptor, type 2 | -0.0107553 |
| TNC | tenascin C | -0.0102655 |
| CARMIL1 | capping protein regulator and myosin 1 linker 1 | -0.0102109 |
| IKZF1 | IKAROS family zinc finger 1 (Ikaros) | -0.0101611 |
| SFRP1 | secreted frizzled-related protein 1 | -0.00991734 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.00986916 |
| LY75 | lymphocyte antigen 75 | -0.00973385 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00971035 |
| SYT1 | synaptotagmin I | -0.00969066 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.0092946 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.0092326 |
| PAN2 | PAN2 poly(A) specific ribonuclease subunit | -0.00922194 |
| KRT15 | keratin 15, type I | -0.0091422 |
| HSPA1A | heat shock 70kDa protein 1A | -0.0090304 |
| IL1RN | interleukin 1 receptor antagonist | -0.00902321 |
| MGLL | monoglyceride lipase | -0.00895532 |
| BEX1 | brain expressed, X-linked 1 | -0.00894408 |
| CLU | clusterin | -0.00892261 |
| MMP7 | matrix metallopeptidase 7 | -0.00891922 |
| CXCL14 | chemokine (C-X-C motif) ligand 14 | -0.00889254 |
| TUBB2B | tubulin, beta 2B class IIb | -0.00885584 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00877404 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | -0.00865784 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00860547 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00858355 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 | -0.00851184 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | -0.00840877 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | -0.00840125 |
| XPO7 | exportin 7 | -0.00829959 |
| PIP | prolactin-induced protein | -0.00819619 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.00806332 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0080463 |
| RCAN1 | regulator of calcineurin 1 | -0.00798395 |
| LEF1 | lymphoid enhancer-binding factor 1 | -0.00790643 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.00777651 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00770006 |
| PDZK1IP1 | PDZK1 interacting protein 1 | -0.00768959 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.00760119 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00754649 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0075362 |
| FMO2 | flavin containing monooxygenase 2 (non-functional) | -0.00752142 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00749283 |
| LAMC2 | laminin, gamma 2 | -0.00748712 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00747008 |
| IRS2 | insulin receptor substrate 2 | -0.00746659 |
| SELL | selectin L | -0.00746626 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | -0.00737174 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.00736825 |
| G0S2 | G0/G1 switch 2 | -0.00735753 |
| NRCAM | neuronal cell adhesion molecule | -0.00732865 |
| AZGP1 | alpha-2-glycoprotein 1, zinc-binding | -0.00726127 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.00723588 |
| ALB | albumin | -0.00719673 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.00719089 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00715912 |
| BHLHE41 | basic helix-loop-helix family, member e41 | -0.00714669 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.00710751 |
| TUBB6 | tubulin, beta 6 class V | -0.0070424 |
| STK10 | serine/threonine kinase 10 | -0.0070423 |
| CH25H | cholesterol 25-hydroxylase | -0.00697239 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.00696236 |
| CSTA | cystatin A (stefin A) | -0.00693722 |
| CCR1 | chemokine (C-C motif) receptor 1 | -0.00686699 |
| C5AR1 | complement component 5a receptor 1 | -0.00684912 |
| MAGEA3 | melanoma antigen family A3 | -0.00678643 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | -0.00676925 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | -0.00675853 |
| PPFIBP2 | PTPRF interacting protein, binding protein 2 (liprin beta 2) | -0.00674808 |
| PLBD1 | phospholipase B domain containing 1 | -0.00673107 |
| CXCL2 | chemokine (C-X-C motif) ligand 2 | -0.00672898 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00668268 |
| ST6GALNAC2 | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 2 | -0.00667891 |
| MIA | melanoma inhibitory activity | -0.00667347 |
| GNE | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | -0.00667062 |
| SRPX | sushi-repeat containing protein, X-linked | -0.00663529 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00659345 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0065875 |
| OLFM4 | olfactomedin 4 | -0.00658047 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | -0.00654628 |
| MB | myoglobin | -0.00653219 |
| PLXNC1 | plexin C1 | -0.00648939 |
| CX3CR1 | chemokine (C-X3-C motif) receptor 1 | -0.00642951 |
| PDLIM4 | PDZ and LIM domain 4 | -0.0064266 |
| GPX2 | glutathione peroxidase 2 | -0.0064215 |
| CYFIP2 | cytoplasmic FMR1 interacting protein 2 | -0.00640819 |
| PLXNB2 | plexin B2 | -0.00640065 |
| PLIN2 | perilipin 2 | -0.00639411 |
| PIK3CD | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta | -0.00638825 |
| EHD3 | EH-domain containing 3 | -0.00634965 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00634813 |
| LAMA3 | laminin, alpha 3 | -0.00634489 |
| HMG20B | high mobility group 20B | -0.00633455 |
| CRISPLD2 | cysteine-rich secretory protein LCCL domain containing 2 | -0.00629709 |
| DACH1 | dachshund family transcription factor 1 | -0.00629381 |
| ATF3 | activating transcription factor 3 | -0.00623873 |
| MVP | major vault protein | -0.00618354 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.00617688 |
| SOX10 | SRY (sex determining region Y)-box 10 | -0.00615716 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0061525 |
| DUSP4 | dual specificity phosphatase 4 | -0.00611403 |
| MLPH | melanophilin | -0.00608035 |
| KYNU | kynureninase | -0.0060795 |
| ACKR3 | atypical chemokine receptor 3 | -0.00607848 |
| TGM2 | transglutaminase 2 | -0.00607041 |
| TSPAN8 | tetraspanin 8 | -0.0060596 |
| LMCD1 | LIM and cysteine-rich domains 1 | -0.00605379 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.00605035 |
| PXDN | peroxidasin | -0.00602172 |
| TBC1D9 | TBC1 domain family, member 9 (with GRAM domain) | -0.00601981 |
| SERINC5 | serine incorporator 5 | -0.00601903 |
| GPNMB | glycoprotein (transmembrane) nmb | -0.00599665 |
| FA2H | fatty acid 2-hydroxylase | -0.00597609 |
| MFAP5 | microfibrillar associated protein 5 | -0.00597527 |
| AQP9 | aquaporin 9 | -0.00597514 |
| PTGES | prostaglandin E synthase | -0.00596282 |
| OXTR | oxytocin receptor | -0.00595776 |
| TBC1D4 | TBC1 domain family, member 4 | -0.00595677 |
| LPIN1 | lipin 1 | -0.00595475 |
| DCLK1 | doublecortin-like kinase 1 | -0.00595093 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.00594756 |
| HMGA2 | high mobility group AT-hook 2 | -0.00592338 |
| QPCT | glutaminyl-peptide cyclotransferase | -0.00589419 |
| LYST | lysosomal trafficking regulator | -0.00589373 |
| IL7R | interleukin 7 receptor | -0.00588888 |
| AOX1 | aldehyde oxidase 1 | -0.00587977 |
| CSAD | cysteine sulfinic acid decarboxylase | -0.00586088 |
| CHGB | chromogranin B | -0.00585886 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00585416 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | -0.00584145 |
| NAV2 | neuron navigator 2 | -0.00583513 |
| CES1 | carboxylesterase 1 | -0.00583181 |
| PYGB | phosphorylase, glycogen; brain | -0.00582763 |
| PLCB4 | phospholipase C, beta 4 | -0.00582722 |
| HLA-DRA | major histocompatibility complex, class II, DR alpha | -0.00582604 |
| CEBPA | CCAAT/enhancer binding protein (C/EBP), alpha | -0.00580569 |
| GALNT6 | polypeptide N-acetylgalactosaminyltransferase 6 | -0.00577891 |
| NFIB | nuclear factor I/B | -0.00575225 |
| VCL | vinculin | -0.00571782 |
| IL1B | interleukin 1, beta | -0.00568138 |
| SLC2A10 | solute carrier family 2 (facilitated glucose transporter), member 10 | -0.00566824 |
| COL9A3 | collagen, type IX, alpha 3 | -0.00566153 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.00565785 |
| CBX6 | chromobox homolog 6 | -0.00563037 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.00560424 |
| VPS37B | vacuolar protein sorting 37 homolog B (S. cerevisiae) | -0.00558872 |
| GZMB | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | -0.00558534 |
| EDNRB | endothelin receptor type B | -0.00557034 |
| TCF7 | transcription factor 7 (T-cell specific, HMG-box) | -0.00556989 |
| KRT14 | keratin 14, type I | -0.00556808 |
| MMP3 | matrix metallopeptidase 3 | -0.00556458 |
| NARS1 | asparaginyl-tRNA synthetase 1 | -0.00555681 |
| TJP2 | tight junction protein 2 | -0.00555273 |
| ZNF185 | zinc finger protein 185 (LIM domain) | -0.0055348 |
| MAL | mal, T-cell differentiation protein | -0.00552469 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.00551862 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.00551693 |
| FHOD3 | formin homology 2 domain containing 3 | -0.00551288 |
| ADAM12 | ADAM metallopeptidase domain 12 | -0.00550957 |
| NCKAP1L | NCK-associated protein 1-like | -0.00549608 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.00549412 |
| MAOB | monoamine oxidase B | -0.00548105 |
| NLGN4X | neuroligin 4, X-linked | -0.00547511 |
| GBP2 | guanylate binding protein 2, interferon-inducible | -0.00547303 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00544889 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.00543479 |
| CDO1 | cysteine dioxygenase type 1 | -0.00543456 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.00543068 |
| AUTS2 | autism susceptibility candidate 2 | -0.0054104 |
| SORD | sorbitol dehydrogenase | -0.00540669 |
| WDR7 | WD repeat domain 7 | -0.00540654 |
| AHR | aryl hydrocarbon receptor | -0.00540395 |
| BICC1 | BicC family RNA binding protein 1 | -0.00539883 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00539426 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00537594 |
| NCF2 | neutrophil cytosolic factor 2 | -0.00536695 |
| GOLGA8A | golgin A8 family, member A | -0.00535759 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00535625 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.00534321 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | -0.00533873 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.00531816 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00531166 |
| SLC5A6 | solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 | -0.00530546 |
| KRT7 | keratin 7, type II | -0.00530544 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.00528383 |
| SIDT2 | SID1 transmembrane family, member 2 | -0.00527593 |
| GAS1 | growth arrest-specific 1 | -0.00526568 |
| RELN | reelin | -0.00525889 |
| DUSP5 | dual specificity phosphatase 5 | -0.0052555 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00524409 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | -0.00524313 |
| RUNX3 | runt-related transcription factor 3 | -0.0052275 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.00520838 |
| STAT5A | signal transducer and activator of transcription 5A | -0.00520075 |
| SYNM | synemin, intermediate filament protein | -0.0051974 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.00519521 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.00518293 |
| MX1 | MX dynamin-like GTPase 1 | -0.00518262 |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) | -0.00518074 |
| KRT18 | keratin 18, type I | -0.0051695 |
| POLR2D | polymerase (RNA) II (DNA directed) polypeptide D | -0.00515652 |
| PFKL | phosphofructokinase, liver | -0.00514569 |
| TRIM29 | tripartite motif containing 29 | -0.00514367 |
| EPHB2 | EPH receptor B2 | -0.00513976 |
| CXCL6 | chemokine (C-X-C motif) ligand 6 | -0.00513319 |
| REG3A | regenerating islet-derived 3 alpha | -0.00512855 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.00512717 |
| NEBL | nebulette | -0.00512369 |
| MX2 | MX dynamin-like GTPase 2 | -0.0051132 |
| XYLT1 | xylosyltransferase I | -0.00510245 |
| DNAJC12 | DnaJ (Hsp40) homolog, subfamily C, member 12 | -0.00509613 |
| HCLS1 | hematopoietic cell-specific Lyn substrate 1 | -0.005078 |
| CDIPT | CDP-diacylglycerol--inositol 3-phosphatidyltransferase | -0.00506368 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.00505627 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | -0.00504422 |
| TWIST1 | twist family bHLH transcription factor 1 | -0.00503435 |
| ANXA2P2 | annexin A2 pseudogene 2 | -0.0050274 |
| IL2RG | interleukin 2 receptor, gamma | -0.00501674 |
| MAFB | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B | -0.00501499 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.00501399 |
| TRIB2 | tribbles pseudokinase 2 | -0.00499766 |
| AIM2 | absent in melanoma 2 | -0.00499753 |
| TSPAN14 | tetraspanin 14 | -0.0049839 |
| ADM | adrenomedullin | -0.00497702 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.00497592 |
| LONP2 | lon peptidase 2, peroxisomal | -0.00497021 |
| HK2 | hexokinase 2 | -0.00496844 |
| IFI44L | interferon-induced protein 44-like | -0.00496791 |
| MST1 | macrophage stimulating 1 | -0.00496223 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00496041 |
| WWOX | WW domain containing oxidoreductase | -0.00495554 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.00494905 |
| IRAK3 | interleukin-1 receptor-associated kinase 3 | -0.00494676 |
| HOXC6 | homeobox C6 | -0.00493847 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.00492273 |
| CCR7 | chemokine (C-C motif) receptor 7 | -0.00492174 |
| MFAP3L | microfibrillar-associated protein 3-like | -0.00491305 |
| STUB1 | STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase | -0.0049104 |
| AHNAK | AHNAK nucleoprotein | -0.00490832 |
| UPF3B | UPF3 regulator of nonsense transcripts homolog B (yeast) | -0.00489408 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0048652 |
| STK38 | serine/threonine kinase 38 | -0.00486504 |
| SERPINB5 | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | -0.00486116 |
