EPOR Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description erythropoietin receptor|This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants.[provided by RefSeq, May 2010] (NCBI Entrez Gene Database, 2057)
External Link https://ncbi.nlm.nih.gov/gene/2057
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Genes

500 genes differentially expressed following the EPOR gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
MAP7 microtubule-associated protein 7 0.0220183
CA2 carbonic anhydrase II 0.0137138
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.0134112
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.0132013
SLC5A6 solute carrier family 5 (sodium/multivitamin and iodide cotransporter), member 6 0.0128708
FGFR3 fibroblast growth factor receptor 3 0.0119361
CD40 CD40 molecule, TNF receptor superfamily member 5 0.0113299
FASN fatty acid synthase 0.0111942
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.0108892
GSTA1 glutathione S-transferase alpha 1 0.0104855
GLUL glutamate-ammonia ligase 0.01008
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.0100769
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.0099695
ESR1 estrogen receptor 1 0.00967672
MMP9 matrix metallopeptidase 9 0.00962177
KRT13 keratin 13, type I 0.00954505
TFF1 trefoil factor 1 0.00953072
NRGN neurogranin (protein kinase C substrate, RC3) 0.00919453
SDC2 syndecan 2 0.00900816
TMSB15A thymosin beta 15a 0.00894757
GREM1 gremlin 1, DAN family BMP antagonist 0.00872199
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.00863137
MSMO1 methylsterol monooxygenase 1 0.00860432
BIRC5 baculoviral IAP repeat containing 5 0.00851595
S100A8 S100 calcium binding protein A8 0.00827155
RAD23B RAD23 homolog B (S. cerevisiae) 0.00823275
DGKZ diacylglycerol kinase, zeta 0.00819975
KRT19 keratin 19, type I 0.0081837
DCK deoxycytidine kinase 0.00808197
MREG melanoregulin 0.00804858
CCNA2 cyclin A2 0.0080476
SLC6A8 solute carrier family 6 (neurotransmitter transporter), member 8 0.00796685
CXCL9 chemokine (C-X-C motif) ligand 9 0.00791193
GAL galanin/GMAP prepropeptide 0.00777021
INSIG1 insulin induced gene 1 0.00772077
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 0.00770124
PRC1 protein regulator of cytokinesis 1 0.00764716
H1-10 H1.10 linker histone 0.00755405
PDAP1 PDGFA associated protein 1 0.00754285
HILPDA hypoxia inducible lipid droplet-associated 0.00751202
ORC1 origin recognition complex, subunit 1 0.00745818
IGFBP2 insulin-like growth factor binding protein 2, 36kDa 0.00738632
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.00738189
RAB25 RAB25, member RAS oncogene family 0.00738171
APOA1 apolipoprotein A-I 0.00738118
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.00738114
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.00732668
HMBS hydroxymethylbilane synthase 0.00721384
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.00719824
ENO2 enolase 2 (gamma, neuronal) 0.0071928
POLE2 polymerase (DNA directed), epsilon 2, accessory subunit 0.00714561
RNPS1 RNA binding protein S1, serine-rich domain 0.00712188
CDH3 cadherin 3, type 1, P-cadherin (placental) 0.00708239
OIP5 Opa interacting protein 5 0.00704674
CSTA cystatin A (stefin A) 0.00702482
KIF20A kinesin family member 20A 0.00701346
FABP4 fatty acid binding protein 4, adipocyte 0.00700856
BEX1 brain expressed, X-linked 1 0.00698915
NEK2 NIMA-related kinase 2 0.00694786
ADAM28 ADAM metallopeptidase domain 28 0.00691235
FKBP5 FK506 binding protein 5 0.00688513
HCRT hypocretin (orexin) neuropeptide precursor 0.00682842
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae) 0.0067079
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.00669714
TPD52L1 tumor protein D52-like 1 0.00669498
STXBP2 syntaxin binding protein 2 0.00668633
AURKB aurora kinase B 0.00667837
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.00667548
AMD1 adenosylmethionine decarboxylase 1 0.00664617
CALR calreticulin 0.00664045
APMAP adipocyte plasma membrane associated protein 0.00660268
COMMD8 COMM domain containing 8 0.00658379
PLK1 polo-like kinase 1 0.00657913
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.00656304
ATG5 autophagy related 5 0.00656029
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1 0.00655171
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.00654825
COL10A1 collagen, type X, alpha 1 0.00654449
NDUFA4L2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 0.00652079
TSPAN13 tetraspanin 13 0.00651698
SNRPB small nuclear ribonucleoprotein polypeptides B and B1 0.00651366
NUSAP1 nucleolar and spindle associated protein 1 0.00646933
HHEX hematopoietically expressed homeobox 0.00645358
CRYM crystallin, mu 0.00644333
SRSF1 serine/arginine-rich splicing factor 1 0.00642814
ELP5 elongator acetyltransferase complex subunit 5 0.0064271
MAT2A methionine adenosyltransferase II, alpha 0.00640914
KLHDC3 kelch domain containing 3 0.0063901
CD36 CD36 molecule (thrombospondin receptor) 0.00638377
ARMT1 acidic residue methyltransferase 1 0.00627948
DHCR7 7-dehydrocholesterol reductase 0.00627586
CDCA3 cell division cycle associated 3 0.00627331
IDO1 indoleamine 2,3-dioxygenase 1 0.00626087
FABP6 fatty acid binding protein 6, ileal 0.00623734
FOXM1 forkhead box M1 0.00623312
CLDND1 claudin domain containing 1 0.00622078
MNDA myeloid cell nuclear differentiation antigen 0.00619645
GINS1 GINS complex subunit 1 (Psf1 homolog) 0.00619616
SPC25 SPC25, NDC80 kinetochore complex component 0.00619154
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.00618945
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 0.00615479
RAD23A RAD23 homolog A (S. cerevisiae) 0.00612526
SIAH2 siah E3 ubiquitin protein ligase 2 0.00610287
ATP10D ATPase, class V, type 10D 0.0060946
NDC1 NDC1 transmembrane nucleoporin 0.00606276
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D 0.00605107
ITGAE integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) 0.00603373
SINHCAF SIN3-HDAC complex associated factor 0.00595789
PBK PDZ binding kinase 0.00594081
PRPF19 pre-mRNA processing factor 19 0.00592573
EMX2 empty spiracles homeobox 2 0.00590348
COG7 component of oligomeric golgi complex 7 0.00588919
AP2S1 adaptor-related protein complex 2, sigma 1 subunit 0.00588455
ECT2 epithelial cell transforming 2 0.00588322
PSRC1 proline/serine-rich coiled-coil 1 0.00587644
RAB38 RAB38, member RAS oncogene family 0.00587035
GTSE1 G-2 and S-phase expressed 1 0.00586022
CXADR coxsackie virus and adenovirus receptor 0.00585869
AUTS2 autism susceptibility candidate 2 0.00585851
PRMT1 protein arginine methyltransferase 1 0.00582875
LSP1 lymphocyte-specific protein 1 0.0057943
PITX1 paired-like homeodomain 1 0.00579207
SPINT2 serine peptidase inhibitor, Kunitz type, 2 0.00577983
NTS neurotensin 0.00576178
PFKL phosphofructokinase, liver 0.00575524
PDZK1 PDZ domain containing 1 0.00574545
KRT8 keratin 8, type II 0.00574387
ILK integrin-linked kinase 0.00574305
U2AF1 U2 small nuclear RNA auxiliary factor 1 0.00573999
EPHA1 EPH receptor A1 0.00566628
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1 0.00565383
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 0.00563714
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.00563437
HBZ hemoglobin, zeta 0.005624
SNRPA small nuclear ribonucleoprotein polypeptide A 0.00561027
FGFR2 fibroblast growth factor receptor 2 0.00559016
QRSL1 glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1 0.00558543
ESRP1 epithelial splicing regulatory protein 1 0.00558427
COL18A1 collagen, type XVIII, alpha 1 0.00556962
MED28 mediator complex subunit 28 0.00556664
RMI1 RecQ mediated genome instability 1 0.00556056
CENPF centromere protein F, 350/400kDa 0.00554345
HCK HCK proto-oncogene, Src family tyrosine kinase 0.00552993
ABHD10 abhydrolase domain containing 10 0.0055243
TFRC transferrin receptor 0.00551265
PXDN peroxidasin 0.00550744
ASF1B anti-silencing function 1B histone chaperone 0.0054787
GUCY1A3 guanylate cyclase 1, soluble, alpha 3 0.00547337
DEPDC1 DEP domain containing 1 0.00546933
PCLO piccolo presynaptic cytomatrix protein 0.00546912
S100A9 S100 calcium binding protein A9 0.00546137
EIF5A eukaryotic translation initiation factor 5A 0.00545556
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1 0.00544265
RCN2 reticulocalbin 2, EF-hand calcium binding domain 0.00543503
NUCKS1 nuclear casein kinase and cyclin-dependent kinase substrate 1 0.00542746
PRR7 proline rich 7 (synaptic) 0.00542544
TCL1A T-cell leukemia/lymphoma 1A 0.00542314
BTK Bruton agammaglobulinemia tyrosine kinase 0.00540597
DBF4 DBF4 zinc finger 0.00538696
GANAB glucosidase, alpha; neutral AB 0.00538276
WASF1 WAS protein family, member 1 0.00537477
RGCC regulator of cell cycle 0.00536133
TBC1D9 TBC1 domain family, member 9 (with GRAM domain) 0.00536102
MCF2L MCF.2 cell line derived transforming sequence-like 0.005356
CPOX coproporphyrinogen oxidase 0.00533939
H2AZ1 H2A.Z variant histone 1 0.00533528
CSK c-src tyrosine kinase 0.00531496
PUM2 pumilio RNA-binding family member 2 0.0052924
NT5DC2 5'-nucleotidase domain containing 2 0.00528471
PEA15 phosphoprotein enriched in astrocytes 15 0.00527981
HADHA hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit 0.00526958
BCKDHA branched chain keto acid dehydrogenase E1, alpha polypeptide 0.00525489
GTF2I general transcription factor IIi 0.00525304
IL7 interleukin 7 0.00524257
CDT1 chromatin licensing and DNA replication factor 1 0.00524041
HYOU1 hypoxia up-regulated 1 0.005219
GJA1 gap junction protein, alpha 1, 43kDa 0.00521687
CA9 carbonic anhydrase IX 0.00521591
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1 0.00521355
MRPL42 mitochondrial ribosomal protein L42 0.00521115
ATXN10 ataxin 10 0.00521061
LMNB2 lamin B2 0.00521038
EHF ets homologous factor 0.00520494
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.00520252
CRABP2 cellular retinoic acid binding protein 2 0.00520107
LIG1 ligase I, DNA, ATP-dependent 0.00519269
CNOT3 CCR4-NOT transcription complex, subunit 3 0.00518626
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 0.00516668
MRPS12 mitochondrial ribosomal protein S12 0.00516322
MMP11 matrix metallopeptidase 11 0.0051622
ECI1 enoyl-CoA delta isomerase 1 0.00516191
ACP1 acid phosphatase 1, soluble 0.00515307
PPID peptidylprolyl isomerase D 0.00514829
HMGB2 high mobility group box 2 0.00512694
ZNF652 zinc finger protein 652 0.00512625
CCKBR cholecystokinin B receptor 0.00512588
STMN1 stathmin 1 0.00511848
PDE2A phosphodiesterase 2A, cGMP-stimulated 0.00511738
WFDC2 WAP four-disulfide core domain 2 0.00511619
LBR lamin B receptor 0.00509147
SPARCL1 SPARC-like 1 (hevin) 0.00508789
LTF lactotransferrin 0.00508555
LRRC15 leucine rich repeat containing 15 0.00506986
CAND1 cullin-associated and neddylation-dissociated 1 0.00506656
NGFRAP1 nerve growth factor receptor (TNFRSF16) associated protein 1 0.0050568
KIF23 kinesin family member 23 0.00504622
NCAPH non-SMC condensin I complex, subunit H 0.00504331
TDP1 tyrosyl-DNA phosphodiesterase 1 0.0050381
ALPL alkaline phosphatase, liver/bone/kidney 0.00503621
CENPU centromere protein U 0.00502566
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.00502273
ALCAM activated leukocyte cell adhesion molecule 0.00501845
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 0.00501844
STEAP1B STEAP family member 1B 0.00501446
RBM38 RNA binding motif protein 38 0.00500696
SPINK5 serine peptidase inhibitor, Kazal type 5 0.00500325
DTYMK deoxythymidylate kinase (thymidylate kinase) 0.00500131
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 0.005001
PTMS parathymosin 0.0049862
PAM16 presequence translocase-associated motor 16 homolog (S. cerevisiae) 0.0049859
RUVBL1 RuvB-like AAA ATPase 1 0.00497943
RAD51AP1 RAD51 associated protein 1 0.00496524
ZNF274 zinc finger protein 274 0.00496227
YKT6 YKT6 v-SNARE homolog (S. cerevisiae) 0.0049581
CDC20 cell division cycle 20 0.00495764
SRSF7 serine/arginine-rich splicing factor 7 0.00495564
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00494899
STAT5B signal transducer and activator of transcription 5B 0.00494232
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 0.00493649
COPS4 COP9 signalosome subunit 4 0.00493063
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.00491819
PTGER3 prostaglandin E receptor 3 (subtype EP3) 0.0049116
RBMX RNA binding motif protein, X-linked 0.00491045
TRABD TraB domain containing 0.0049032
FOXE1 forkhead box E1 0.00489959
TTK TTK protein kinase 0.00489257
TOP2A topoisomerase (DNA) II alpha 170kDa 0.00489068
COPS7A COP9 signalosome subunit 7A 0.00488998
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.00488349
UBE2D3 ubiquitin-conjugating enzyme E2D 3 0.00487167
BSPRY B-box and SPRY domain containing 0.00487151
LAPTM5 lysosomal protein transmembrane 5 0.00487013
SFI1 Sfi1 homolog, spindle assembly associated (yeast) 0.00486885
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.00486845
NOP16 NOP16 nucleolar protein 0.00486613
TSPAN5 tetraspanin 5 0.00485897
SPTSSA serine palmitoyltransferase, small subunit A 0.0048552
RETREG1 reticulophagy regulator 1 0.00484984
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.00484923
PF4 platelet factor 4 0.00484693

decreased expression

Symbol Name Standardized Value
IFI27 interferon, alpha-inducible protein 27 -0.0173217
IFI44L interferon-induced protein 44-like -0.015548
IFI6 interferon, alpha-inducible protein 6 -0.0153249
ISG15 ISG15 ubiquitin-like modifier -0.0152935
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.0142784
LGALS3BP lectin, galactoside-binding, soluble, 3 binding protein -0.013342
MX1 MX dynamin-like GTPase 1 -0.0126799
AKR1C3 aldo-keto reductase family 1, member C3 -0.0124856
G0S2 G0/G1 switch 2 -0.0120302
TSPAN8 tetraspanin 8 -0.0119294
ITM2A integral membrane protein 2A -0.0117518
GNAS GNAS complex locus -0.0117319
JAG1 jagged 1 -0.0116411
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa -0.0115169
RPS4Y1 ribosomal protein S4, Y-linked 1 -0.0114622
TM4SF1 transmembrane 4 L six family member 1 -0.011459
AKR1C2 aldo-keto reductase family 1, member C2 -0.0113038
SYNM synemin, intermediate filament protein -0.0112506
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1 -0.0109849
TENT5A terminal nucleotidyltransferase 5A -0.0109359
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b -0.0109146
CCL20 chemokine (C-C motif) ligand 20 -0.0108937
DKK1 dickkopf WNT signaling pathway inhibitor 1 -0.0108522
ZMAT3 zinc finger, matrin-type 3 -0.0106145
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -0.0105828
CRYAB crystallin, alpha B -0.0104178
CXCL8 chemokine (C-X-C motif) ligand 8 -0.0103317
S100P S100 calcium binding protein P -0.0101667
SPINK1 serine peptidase inhibitor, Kazal type 1 -0.0100584
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) -0.00979436
SRPX sushi-repeat containing protein, X-linked -0.00967134
HMOX1 heme oxygenase 1 -0.00960529
ASS1 argininosuccinate synthase 1 -0.0095841
ALDH1A3 aldehyde dehydrogenase 1 family, member A3 -0.00944656
SSBP2 single-stranded DNA binding protein 2 -0.00940256
RPS27L ribosomal protein S27-like -0.00937
CCN2 cellular communication network factor 2 -0.00926595
COQ8A coenzyme Q8A -0.00919193
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa -0.00914977
ABCA1 ATP-binding cassette, sub-family A (ABC1), member 1 -0.00914731
COL5A2 collagen, type V, alpha 2 -0.00907371
APOD apolipoprotein D -0.00904606
INAVA innate immunity activator -0.00896569
HSPA1A heat shock 70kDa protein 1A -0.00895965
LAMC2 laminin, gamma 2 -0.00888934
IFI44 interferon-induced protein 44 -0.00879245
MVP major vault protein -0.00870233
SLC39A4 solute carrier family 39 (zinc transporter), member 4 -0.00868545
ACTA1 actin, alpha 1, skeletal muscle -0.00865373
PMEPA1 prostate transmembrane protein, androgen induced 1 -0.00864252
AKR1C1 aldo-keto reductase family 1, member C1 -0.00853915
LIMCH1 LIM and calponin homology domains 1 -0.00853216
TLR4 toll-like receptor 4 -0.00849808
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3 -0.00848086
RTN2 reticulon 2 -0.00845466
SMAD7 SMAD family member 7 -0.00844152
LAMB3 laminin, beta 3 -0.00838192
CKM creatine kinase, muscle -0.00835794
CX3CR1 chemokine (C-X3-C motif) receptor 1 -0.0083433
AMIGO2 adhesion molecule with Ig-like domain 2 -0.00833446
KRT14 keratin 14, type I -0.00832588
KLF10 Kruppel-like factor 10 -0.00831775
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -0.00831573
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.00828942
ATP1A2 ATPase, Na+/K+ transporting, alpha 2 polypeptide -0.00827992
AQP3 aquaporin 3 (Gill blood group) -0.00827727
ANK2 ankyrin 2, neuronal -0.00821717
GPX2 glutathione peroxidase 2 -0.00821136
LAMA3 laminin, alpha 3 -0.00817462
SFN stratifin -0.00813651
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase) -0.00812353
KLHL41 kelch-like family member 41 -0.00806381
TGFBI transforming growth factor, beta-induced, 68kDa -0.00804072
LIF leukemia inhibitory factor -0.00802954
TXLNA taxilin alpha -0.00800516
POSTN periostin, osteoblast specific factor -0.00798145
DNMBP dynamin binding protein -0.00797621
HGF hepatocyte growth factor (hepapoietin A; scatter factor) -0.00793906
MX2 MX dynamin-like GTPase 2 -0.00792349
IGFBP6 insulin-like growth factor binding protein 6 -0.00791796
ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 -0.0078724
ATP9A ATPase, class II, type 9A -0.00780185
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 -0.00775087
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00770066
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog -0.00765599
HSPB8 heat shock 22kDa protein 8 -0.00761262
MAP1B microtubule-associated protein 1B -0.00756569
DEFB1 defensin, beta 1 -0.00755489
SECISBP2L SECIS binding protein 2-like -0.00753042
SQSTM1 sequestosome 1 -0.00745887
MPDZ multiple PDZ domain protein -0.00740158
DCN decorin -0.00739801
HNMT histamine N-methyltransferase -0.00737923
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.00737262
TGFBR3 transforming growth factor, beta receptor III -0.00736861
FTH1 ferritin, heavy polypeptide 1 -0.00736117
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 -0.00735995
GABARAPL1 GABA(A) receptor-associated protein like 1 -0.00734439
SRC SRC proto-oncogene, non-receptor tyrosine kinase -0.0073334
AOC1 amine oxidase, copper containing 1 -0.00732387
ITGAV integrin, alpha V -0.00731955
IRS2 insulin receptor substrate 2 -0.00731817
MYL1 myosin, light chain 1, alkali; skeletal, fast -0.00729229
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00726843
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B -0.00723811
JMJD1C jumonji domain containing 1C -0.00722436
MGLL monoglyceride lipase -0.00721969
LAMA2 laminin, alpha 2 -0.00721642
NRCAM neuronal cell adhesion molecule -0.00718214
ZCCHC24 zinc finger, CCHC domain containing 24 -0.00716467
PCDH9 protocadherin 9 -0.00716064
TNNC2 troponin C type 2 (fast) -0.00713774
CDH17 cadherin 17, LI cadherin (liver-intestine) -0.00711865
S100A11 S100 calcium binding protein A11 -0.00709543
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3 -0.00705242
PDE4DIP phosphodiesterase 4D interacting protein -0.00704513
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2 -0.00701012
GOLGA8H golgin A8 family, member H -0.00700346
PLAAT3 phospholipase A and acyltransferase 3 -0.00700176
OASL 2'-5'-oligoadenylate synthetase-like -0.0069901
ITPRID2 ITPR interacting domain containing 2 -0.00698888
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase) -0.00698258
CTTN cortactin -0.00697008
TSPAN7 tetraspanin 7 -0.00694711
CSRP1 cysteine and glycine-rich protein 1 -0.00693026
LGALS3 lectin, galactoside-binding, soluble, 3 -0.00688819
KIF13B kinesin family member 13B -0.00688175
IRF7 interferon regulatory factor 7 -0.00687231
HBEGF heparin-binding EGF-like growth factor -0.0068586
IGF2R insulin-like growth factor 2 receptor -0.00685553
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 -0.00685189
XAF1 XIAP associated factor 1 -0.0068492
RBPMS RNA binding protein with multiple splicing -0.00684863
MAN1C1 mannosidase, alpha, class 1C, member 1 -0.00684139
NBR1 neighbor of BRCA1 gene 1 -0.00683886
TRIM22 tripartite motif containing 22 -0.00682338
TTN titin -0.00682099
TFPI2 tissue factor pathway inhibitor 2 -0.00681712
COL3A1 collagen, type III, alpha 1 -0.00680646
CAPN3 calpain 3, (p94) -0.00680486
PDLIM1 PDZ and LIM domain 1 -0.00680361
PRKCA protein kinase C, alpha -0.00679509
BCAS1 breast carcinoma amplified sequence 1 -0.00678897
IGF1R insulin-like growth factor 1 receptor -0.00677785
EMP1 epithelial membrane protein 1 -0.00677447
IFIT5 interferon-induced protein with tetratricopeptide repeats 5 -0.00674837
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.0067482
MT1E metallothionein 1E -0.00673328
RAMP1 receptor (G protein-coupled) activity modifying protein 1 -0.00672845
GBP2 guanylate binding protein 2, interferon-inducible -0.00672626
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) -0.00672549
SPATA20 spermatogenesis associated 20 -0.00671928
DST dystonin -0.00668685
ACTA2 actin, alpha 2, smooth muscle, aorta -0.0066768
BAMBI BMP and activin membrane-bound inhibitor -0.00667409
CALB1 calbindin 1, 28kDa -0.00665857
BIN1 bridging integrator 1 -0.00665013
MYBPC1 myosin binding protein C, slow type -0.00665004
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -0.00663164
SPTBN1 spectrin, beta, non-erythrocytic 1 -0.00662274
HOMER1 homer scaffolding protein 1 -0.00661011
KDSR 3-ketodihydrosphingosine reductase -0.00659934
TUBB2B tubulin, beta 2B class IIb -0.00659902
IFITM1 interferon induced transmembrane protein 1 -0.00658788
CDA cytidine deaminase -0.00657439
NFIB nuclear factor I/B -0.00655859
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6 -0.00651201
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2 -0.00647785
SCRG1 stimulator of chondrogenesis 1 -0.00647594
HEPH hephaestin -0.00645314
MAP4 microtubule-associated protein 4 -0.00644401
NPC1 Niemann-Pick disease, type C1 -0.0064429
IFI35 interferon-induced protein 35 -0.00643987
MYOT myotilin -0.00640883
FRMD4B FERM domain containing 4B -0.00640344
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 -0.00638716
MACF1 microtubule-actin crosslinking factor 1 -0.00635232
TMEM100 transmembrane protein 100 -0.00633649
IRF9 interferon regulatory factor 9 -0.00633444
TNNC1 troponin C type 1 (slow) -0.00632929
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -0.00630151
PAMR1 peptidase domain containing associated with muscle regeneration 1 -0.00628839
COL14A1 collagen, type XIV, alpha 1 -0.00628426
PPAP2A phosphatidic acid phosphatase type 2A -0.00624485
GPR137B G protein-coupled receptor 137B -0.00624305
TXNIP thioredoxin interacting protein -0.00623442
SPATS2L spermatogenesis associated, serine-rich 2-like -0.00622807
OLFML3 olfactomedin-like 3 -0.00620404
CASP7 caspase 7, apoptosis-related cysteine peptidase -0.00619668
RRBP1 ribosome binding protein 1 -0.00617767
MXRA5 matrix-remodelling associated 5 -0.00617537
IER5 immediate early response 5 -0.00617399
SNAI2 snail family zinc finger 2 -0.00616906
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.00616711
MUC13 mucin 13, cell surface associated -0.00613638
CTSK cathepsin K -0.00613472
SLC18A1 solute carrier family 18 (vesicular monoamine transporter), member 1 -0.00611489
LIMK2 LIM domain kinase 2 -0.00611148
S100A4 S100 calcium binding protein A4 -0.00609053
PARP12 poly (ADP-ribose) polymerase family, member 12 -0.00608807
MT1X metallothionein 1X -0.00608606
CTH cystathionine gamma-lyase -0.00607564
PTN pleiotrophin -0.00607084
NAV3 neuron navigator 3 -0.00606937
ATP10B ATPase, class V, type 10B -0.0060674
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) -0.00604631
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1 -0.00602937
EPB41L3 erythrocyte membrane protein band 4.1-like 3 -0.00602832
GALNT2 polypeptide N-acetylgalactosaminyltransferase 2 -0.00602759
TUBA4A tubulin, alpha 4a -0.0060264
DUSP5 dual specificity phosphatase 5 -0.00602596
ALOX5 arachidonate 5-lipoxygenase -0.00602137
DACH1 dachshund family transcription factor 1 -0.00601372
GRB10 growth factor receptor-bound protein 10 -0.00600212
KLHL21 kelch-like family member 21 -0.0059969
FHL2 four and a half LIM domains 2 -0.00599067
PHLDA3 pleckstrin homology-like domain, family A, member 3 -0.00596871
ARMCX3 armadillo repeat containing, X-linked 3 -0.00596663
ZIC1 Zic family member 1 -0.0059349
COL6A3 collagen, type VI, alpha 3 -0.00592845
PCSK5 proprotein convertase subtilisin/kexin type 5 -0.00592207
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -0.00591674
ENAH enabled homolog (Drosophila) -0.00591108
FGF1 fibroblast growth factor 1 (acidic) -0.00590261
LAMB1 laminin, beta 1 -0.00588673
F8 coagulation factor VIII, procoagulant component -0.00588667
AAMDC adipogenesis associated, Mth938 domain containing -0.00588401
CALCA calcitonin-related polypeptide alpha -0.00587758
ECM1 extracellular matrix protein 1 -0.00584706
CLEC3B C-type lectin domain family 3, member B -0.00583962
EIF5B eukaryotic translation initiation factor 5B -0.00583208
MYL2 myosin, light chain 2, regulatory, cardiac, slow -0.00582806
SAMD4A sterile alpha motif domain containing 4A -0.00582529
SFTPB surfactant protein B -0.00582515
CLIC5 chloride intracellular channel 5 -0.00582426
DPYSL2 dihydropyrimidinase-like 2 -0.00582143
CCND2 cyclin D2 -0.00581014
C1GALT1 core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 -0.00580783
PLS3 plastin 3 -0.00580235
USP18 ubiquitin specific peptidase 18 -0.00578858
TKTL1 transketolase-like 1 -0.00578676
COLEC12 collectin sub-family member 12 -0.00576202
MET MET proto-oncogene, receptor tyrosine kinase -0.00576004
ZBTB10 zinc finger and BTB domain containing 10 -0.00575912
FAXDC2 fatty acid hydroxylase domain containing 2 -0.0057502
PRSS3 protease, serine, 3 -0.0057477
QKI QKI, KH domain containing, RNA binding -0.00574406
ZEB2 zinc finger E-box binding homeobox 2 -0.0057347
GLRX glutaredoxin (thioltransferase) -0.00573239
SAMD9 sterile alpha motif domain containing 9 -0.0057315