ER-nucleus signaling pathway Gene Set

Dataset GO Biological Process Annotations 2025
Category structural or functional annotations
Type biological process
Description Any series of molecular signals that conveys information from the endoplasmic reticulum to the nucleus, usually resulting in a change in transcriptional regulation. (Gene Ontology, GO_0006984)
External Link http://amigo.geneontology.org/amigo/term/GO:0006984
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Genes

28 genes participating in the ER-nucleus signaling pathway biological process from the curated GO Biological Process Annotations 2025 dataset.

Symbol Name
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ATF4 activating transcription factor 4
ATF6 activating transcription factor 6
ATF6B activating transcription factor 6 beta
ATG10 autophagy related 10
CREBZF CREB/ATF bZIP transcription factor
DDIT3 DNA-damage-inducible transcript 3
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
ERLIN1 ER lipid raft associated 1
ERLIN2 ER lipid raft associated 2
GSK3B glycogen synthase kinase 3 beta
INSIG1 insulin induced gene 1
INSIG2 insulin induced gene 2
MANF mesencephalic astrocyte-derived neurotrophic factor
MBTPS1 membrane-bound transcription factor peptidase, site 1
MBTPS2 membrane-bound transcription factor peptidase, site 2
NFE2L2 nuclear factor, erythroid 2-like 2
QRICH1 glutamine-rich 1
RPAP2 RNA polymerase II associated protein 2
SCAP SREBF chaperone
SELENOS selenoprotein S
SREBF1 sterol regulatory element binding transcription factor 1
SREBF2 sterol regulatory element binding transcription factor 2
TMCO1 transmembrane and coiled-coil domains 1
TP53 tumor protein p53
WFS1 Wolfram syndrome 1 (wolframin)
XBP1 X-box binding protein 1