ERAS Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description ES cell expressed Ras|This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012] (NCBI Entrez Gene Database, 3266)
External Link http://www.ncbi.nlm.nih.gov/gene/3266
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Genes

4 interacting proteins for ERAS from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase