ERBB2 signaling pathway Gene Set

Dataset GO Biological Process Annotations 2023
Category structural or functional annotations
Type biological process
Description A series of molecular signals initiated by binding of a ligand to a member of the ERBB family of receptors on the surface of a cell, where the signal is transmitted by ERBB2. The pathway ends with regulation of a downstream cellular process, e.g. transcription. ERBB2 receptors are themselves unable to bind to ligands, but act as a signal-amplifying tyrosine kinase within a heterodimeric pair. (Gene Ontology, GO_0038128)
External Link http://amigo.geneontology.org/amigo/term/GO_0038128
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Genes

14 genes participating in the ERBB2 signaling pathway biological process from the curated GO Biological Process Annotations 2023 dataset.

Symbol Name
AREG amphiregulin
CPNE3 copine III
CUL5 cullin 5
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ERBB2 erb-b2 receptor tyrosine kinase 2
EREG epiregulin
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NRG1 neuregulin 1
PTK6 protein tyrosine kinase 6
PTPRR protein tyrosine phosphatase, receptor type, R
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
TGFA transforming growth factor, alpha