ERBB2 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description erb-b2 receptor tyrosine kinase 2|This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported, with the most common allele, Ile654/Ile655, shown here. Amplification and/or overexpression of this gene has been reported in numerous cancers, including breast and ovarian tumors. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2064)
External Link http://www.ncbi.nlm.nih.gov/gene/2064
Similar Terms
Downloads & Tools

Genes

562 interacting proteins for ERBB2 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AARSD1 alanyl-tRNA synthetase domain containing 1
ABI1 abl-interactor 1
ABI2 abl-interactor 2
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ACPP acid phosphatase, prostate
ACSL3 acyl-CoA synthetase long-chain family member 3
ACTA1 actin, alpha 1, skeletal muscle
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTB actin, beta
ACTBL2 actin, beta-like 2
ACTC1 actin, alpha, cardiac muscle 1
ACTG1 actin gamma 1
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ACTR3 ARP3 actin-related protein 3 homolog (yeast)
ADAM17 ADAM metallopeptidase domain 17
AHNAK AHNAK nucleoprotein
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B
ANO5 anoctamin 5
ANXA1 annexin A1
ANXA2 annexin A2
AP1B1 adaptor-related protein complex 1, beta 1 subunit
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP2S1 adaptor-related protein complex 2, sigma 1 subunit
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
APOB apolipoprotein B
ARAF A-Raf proto-oncogene, serine/threonine kinase
AREG amphiregulin
ARMC8 armadillo repeat containing 8
ATAD3A ATPase family, AAA domain containing 3A
ATP1A1 ATPase, Na+/K+ transporting, alpha 1 polypeptide
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
ATP2A3 ATPase, Ca++ transporting, ubiquitous
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide
ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
ATXN10 ataxin 10
BAIAP2 BAI1-associated protein 2
BCAR1 breast cancer anti-estrogen resistance 1
BCAR3 breast cancer anti-estrogen resistance 3
BCR breakpoint cluster region
BLK BLK proto-oncogene, Src family tyrosine kinase
BLNK B-cell linker
BMX BMX non-receptor tyrosine kinase
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
BTC betacellulin
BTK Bruton agammaglobulinemia tyrosine kinase
CACYBP calcyclin binding protein
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CANX calnexin
CAV1 caveolin 1, caveolae protein, 22kDa
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase
CD247 CD247 molecule
CD28 CD28 molecule
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD44 CD44 molecule (Indian blood group)
CD80 CD80 molecule
CD82 CD82 molecule
CD86 CD86 molecule
CDC37 cell division cycle 37
CDCP1 CUB domain containing protein 1
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH10 cadherin 10, type 2 (T2-cadherin)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH12 cadherin 12, type 2 (N-cadherin 2)
CDH13 cadherin 13
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CDH16 cadherin 16, KSP-cadherin
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDH18 cadherin 18, type 2
CDH19 cadherin 19, type 2
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDH20 cadherin 20, type 2
CDH22 cadherin 22, type 2
CDH23 cadherin-related 23
CDH24 cadherin 24, type 2
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDH7 cadherin 7, type 2
CDH8 cadherin 8, type 2
CDH9 cadherin 9, type 2 (T1-cadherin)
CDHR1 cadherin-related family member 1
CDHR2 cadherin-related family member 2
CDK1 cyclin-dependent kinase 1
CDK11A cyclin-dependent kinase 11A
CDK11B cyclin-dependent kinase 11B
CDK4 cyclin-dependent kinase 4
CDK9 cyclin-dependent kinase 9
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CHN1 chimerin 1
CHUK conserved helix-loop-helix ubiquitous kinase
CISH cytokine inducible SH2-containing protein
CKAP4 cytoskeleton-associated protein 4
CLK3 CDC-like kinase 3
CLNK cytokine-dependent hematopoietic cell linker
CLTC clathrin, heavy chain (Hc)
CNTRL centriolin
COL17A1 collagen, type XVII, alpha 1
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSE1L CSE1 chromosome segregation 1-like (yeast)
CSK c-src tyrosine kinase
CSNK1A1 casein kinase 1, alpha 1
CSTA cystatin A (stefin A)
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa
CTNNA2 catenin (cadherin-associated protein), alpha 2
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTNND1 catenin (cadherin-associated protein), delta 1
CTTN cortactin
CUL5 cullin 5
CUX1 cut-like homeobox 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DBR1 debranching RNA lariats 1
DCHS1 dachsous cadherin-related 1
DDR1 discoidin domain receptor tyrosine kinase 1
DDX17 DEAD (Asp-Glu-Ala-Asp) box helicase 17
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
DHCR7 7-dehydrocholesterol reductase
DLG4 discs, large homolog 4 (Drosophila)
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DNAJB8 DnaJ (Hsp40) homolog, subfamily B, member 8
DNAJC10 DnaJ (Hsp40) homolog, subfamily C, member 10
DNM2 dynamin 2
DOCK7 dedicator of cytokinesis 7
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DOK4 docking protein 4
DOK6 docking protein 6
EEA1 early endosome antigen 1
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EFNB1 ephrin-B1
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
EIF3B eukaryotic translation initiation factor 3, subunit B
ENGASE endo-beta-N-acetylglucosaminidase
EPHA2 EPH receptor A2
EPHB4 EPH receptor B4
EPS15 epidermal growth factor receptor pathway substrate 15
ERBB2IP erbb2 interacting protein
ERBB3 erb-b2 receptor tyrosine kinase 3
ERBB4 erb-b2 receptor tyrosine kinase 4
EREG epiregulin
ERRFI1 ERBB receptor feedback inhibitor 1
ESR1 estrogen receptor 1
FAT1 FAT atypical cadherin 1
FAT2 FAT atypical cadherin 2
FAT3 FAT atypical cadherin 3
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FER fer (fps/fes related) tyrosine kinase
FGF1 fibroblast growth factor 1 (acidic)
FGF10 fibroblast growth factor 10
FGF16 fibroblast growth factor 16
FGF17 fibroblast growth factor 17
FGF18 fibroblast growth factor 18
FGF19 fibroblast growth factor 19
FGF2 fibroblast growth factor 2 (basic)
FGF20 fibroblast growth factor 20
FGF22 fibroblast growth factor 22
FGF23 fibroblast growth factor 23
FGF3 fibroblast growth factor 3
FGF4 fibroblast growth factor 4
FGF5 fibroblast growth factor 5
FGF6 fibroblast growth factor 6
FGF7 fibroblast growth factor 7
FGF8 fibroblast growth factor 8 (androgen-induced)
FGF9 fibroblast growth factor 9
FGFR1 fibroblast growth factor receptor 1
FGFR1OP FGFR1 oncogene partner
FGFR1OP2 FGFR1 oncogene partner 2
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FGR FGR proto-oncogene, Src family tyrosine kinase
FHL2 four and a half LIM domains 2
FKBP1A FK506 binding protein 1A, 12kDa
FKBP5 FK506 binding protein 5
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GRAP2 GRB2-related adaptor protein 2
GRB2 growth factor receptor-bound protein 2
GRB7 growth factor receptor-bound protein 7
GSTT1 glutathione S-transferase theta 1
H1FX H1 histone family, member X
H2AFY H2A histone family, member Y
H3F3A H3 histone, family 3A
HACD3 3-hydroxyacyl-CoA dehydratase 3
HBEGF heparin-binding EGF-like growth factor
HDAC6 histone deacetylase 6
HIST1H1E histone cluster 1, H1e
HIST1H2AA histone cluster 1, H2aa
HIST1H2BF histone cluster 1, H2bf
HLA-A major histocompatibility complex, class I, A
HNRNPF heterogeneous nuclear ribonucleoprotein F
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
HNRNPK heterogeneous nuclear ribonucleoprotein K
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1
HSPA1B heat shock 70kDa protein 1B
HSPA2 heat shock 70kDa protein 2
HSPA4 heat shock 70kDa protein 4
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HSPA8 heat shock 70kDa protein 8
HSPA9 heat shock 70kDa protein 9 (mortalin)
HSPB1 heat shock 27kDa protein 1
HSPD1 heat shock 60kDa protein 1 (chaperonin)
IGF1R insulin-like growth factor 1 receptor
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker)
IGHG3 immunoglobulin heavy constant gamma 3 (G3m marker)
IGHG4 immunoglobulin heavy constant gamma 4 (G4m marker)
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGLC1 immunoglobulin lambda constant 1 (Mcg marker)
IGLC2 immunoglobulin lambda constant 2 (Kern-Oz- marker)
IGLC3 immunoglobulin lambda constant 3 (Kern-Oz+ marker)
IGLC6 immunoglobulin lambda constant 6 (Kern+Oz- marker, gene/pseudogene)
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
IL6ST interleukin 6 signal transducer
ILVBL ilvB (bacterial acetolactate synthase)-like
IQGAP1 IQ motif containing GTPase activating protein 1
IRS1 insulin receptor substrate 1
IRS4 insulin receptor substrate 4
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
ITGB4 integrin, beta 4
ITK IL2-inducible T-cell kinase
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JUP junction plakoglobin
KDELR2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
KL klotho
KLB klotho beta
KPNB1 karyopherin (importin) beta 1
KRAS Kirsten rat sarcoma viral oncogene homolog
KRT1 keratin 1, type II
KRT14 keratin 14, type I
KRT17 keratin 17, type I
KRT5 keratin 5, type II
KRT6A keratin 6A, type II
LAT linker for activation of T cells
LAT2 linker for activation of T cells family, member 2
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRPPRC leucine-rich pentatricopeptide repeat containing
LRRC59 leucine rich repeat containing 59
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP2K1 mitogen-activated protein kinase kinase 1
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK8IP1 mitogen-activated protein kinase 8 interacting protein 1
MAPK8IP2 mitogen-activated protein kinase 8 interacting protein 2
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MATK megakaryocyte-associated tyrosine kinase
MEMO1 mediator of cell motility 1
MET MET proto-oncogene, receptor tyrosine kinase
MGST1 microsomal glutathione S-transferase 1
MLF1 myeloid leukemia factor 1
MLF2 myeloid leukemia factor 2
MMP16 matrix metallopeptidase 16 (membrane-inserted)
MRAS muscle RAS oncogene homolog
MUC1 mucin 1, cell surface associated
MUC4 mucin 4, cell surface associated
MYO18A myosin XVIIIA
NCK2 NCK adaptor protein 2
NCKAP1 NCK-associated protein 1
NDUFA4 NDUFA4, mitochondrial complex associated
NELL1 NEL-like 1 (chicken)
NF2 neurofibromin 2 (merlin)
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NOS3 nitric oxide synthase 3 (endothelial cell)
NQO2 NAD(P)H dehydrogenase, quinone 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRG1 neuregulin 1
NRG2 neuregulin 2
NRG3 neuregulin 3
NRG4 neuregulin 4
NUDC nudC nuclear distribution protein
NUDCD3 NudC domain containing 3
OSMR oncostatin M receptor
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PCDH1 protocadherin 1
PCDH10 protocadherin 10
PCDH11X protocadherin 11 X-linked
PCDH11Y protocadherin 11 Y-linked
PCDH12 protocadherin 12
PCDH15 protocadherin-related 15
PCDH18 protocadherin 18
PCDH19 protocadherin 19
PCDH20 protocadherin 20
PCDH7 protocadherin 7
PCDH8 protocadherin 8
PCDH9 protocadherin 9
PCDHA1 protocadherin alpha 1
PCDHA10 protocadherin alpha 10
PCDHA11 protocadherin alpha 11
PCDHA12 protocadherin alpha 12
PCDHA13 protocadherin alpha 13
PCDHA2 protocadherin alpha 2
PCDHA3 protocadherin alpha 3
PCDHA4 protocadherin alpha 4
PCDHA5 protocadherin alpha 5
PCDHA6 protocadherin alpha 6
PCDHA7 protocadherin alpha 7
PCDHA8 protocadherin alpha 8
PCDHA9 protocadherin alpha 9
PCDHAC1 protocadherin alpha subfamily C, 1
PCDHAC2 protocadherin alpha subfamily C, 2
PCDHB1 protocadherin beta 1
PCDHB10 protocadherin beta 10
PCDHB11 protocadherin beta 11
PCDHB12 protocadherin beta 12
PCDHB13 protocadherin beta 13
PCDHB14 protocadherin beta 14
PCDHB15 protocadherin beta 15
PCDHB16 protocadherin beta 16
PCDHB2 protocadherin beta 2
PCDHB3 protocadherin beta 3
PCDHB4 protocadherin beta 4
PCDHB5 protocadherin beta 5
PCDHB6 protocadherin beta 6
PCDHB7 protocadherin beta 7
PCDHB8 protocadherin beta 8
PCDHGA1 protocadherin gamma subfamily A, 1
PCDHGA10 protocadherin gamma subfamily A, 10
PCDHGA11 protocadherin gamma subfamily A, 11
PCDHGA12 protocadherin gamma subfamily A, 12
PCDHGA2 protocadherin gamma subfamily A, 2
PCDHGA3 protocadherin gamma subfamily A, 3
PCDHGA5 protocadherin gamma subfamily A, 5
PCDHGA6 protocadherin gamma subfamily A, 6
PCDHGA7 protocadherin gamma subfamily A, 7
PCDHGA8 protocadherin gamma subfamily A, 8
PCDHGB1 protocadherin gamma subfamily B, 1
PCDHGB2 protocadherin gamma subfamily B, 2
PCDHGB4 protocadherin gamma subfamily B, 4
PCDHGB6 protocadherin gamma subfamily B, 6
PCDHGB7 protocadherin gamma subfamily B, 7
PCDHGC3 protocadherin gamma subfamily C, 3
PCDHGC4 protocadherin gamma subfamily C, 4
PCDHGC5 protocadherin gamma subfamily C, 5
PDPK1 3-phosphoinositide dependent protein kinase 1
PEX19 peroxisomal biogenesis factor 19
PHB prohibitin
PHB2 prohibitin 2
PHLDA1 pleckstrin homology-like domain, family A, member 1
PICK1 protein interacting with PRKCA 1
PIK3C2A phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
PKDREJ polycystin (PKD) family receptor for egg jelly
PKM pyruvate kinase, muscle
PKP2 plakophilin 2
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLXNB1 plexin B1
POLR1A polymerase (RNA) I polypeptide A, 194kDa
POLR1B polymerase (RNA) I polypeptide B, 128kDa
POTEKP POTE ankyrin domain family, member K, pseudogene
PPP1R13B protein phosphatase 1, regulatory subunit 13B
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2CB protein phosphatase 2, catalytic subunit, beta isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCG protein kinase C, gamma
PRKCH protein kinase C, eta
PRKCI protein kinase C, iota
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKD2 protein kinase D2
PRKD3 protein kinase D3
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTK6 protein tyrosine kinase 6
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN12 protein tyrosine phosphatase, non-receptor type 12
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
PTPN3 protein tyrosine phosphatase, non-receptor type 3
PTPRB protein tyrosine phosphatase, receptor type, B
PTPRC protein tyrosine phosphatase, receptor type, C
PTPRD protein tyrosine phosphatase, receptor type, D
PTPRF protein tyrosine phosphatase, receptor type, F
PTPRG protein tyrosine phosphatase, receptor type, G
PTPRJ protein tyrosine phosphatase, receptor type, J
PTPRK protein tyrosine phosphatase, receptor type, K
PTPRO protein tyrosine phosphatase, receptor type, O
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1
PXN paxillin
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RANBP2 RAN binding protein 2
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RBM25 RNA binding motif protein 25
RECK reversion-inducing-cysteine-rich protein with kazal motifs
RHOA ras homolog family member A
RHOB ras homolog family member B
RHOC ras homolog family member C
RIN1 Ras and Rab interactor 1
RIN2 Ras and Rab interactor 2
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RPL17 ribosomal protein L17
RPS15 ribosomal protein S15
RPS2 ribosomal protein S2
RPS26P11 ribosomal protein S26 pseudogene 11
RPS27A ribosomal protein S27a
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA6 ribosomal protein S6 kinase, 90kDa, polypeptide 6
RRAS related RAS viral (r-ras) oncogene homolog
RRAS2 related RAS viral (r-ras) oncogene homolog 2
S100A11 S100 calcium binding protein A11
S100A14 S100 calcium binding protein A14
S100A16 S100 calcium binding protein A16
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SERAC1 serine active site containing 1
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SFN stratifin
SFPQ splicing factor proline/glutamine-rich
SGPL1 sphingosine-1-phosphate lyase 1
SH2B2 SH2B adaptor protein 2
SH2B3 SH2B adaptor protein 3
SH2D1B SH2 domain containing 1B
SH2D2A SH2 domain containing 2A
SH2D3A SH2 domain containing 3A
SH2D5 SH2 domain containing 5
SH3BGRL SH3 domain binding glutamate-rich protein like
SH3BGRL3 SH3 domain binding glutamate-rich protein like 3
SH3BP2 SH3-domain binding protein 2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHC2 SHC (Src homology 2 domain containing) transforming protein 2
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SLA Src-like-adaptor
SLA2 Src-like-adaptor 2
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2
SLC25A1 solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC3A2 solute carrier family 3 (amino acid transporter heavy chain), member 2
SLC7A5 solute carrier family 7 (amino acid transporter light chain, L system), member 5
SLIRP SRA stem-loop interacting RNA binding protein
SOCS1 suppressor of cytokine signaling 1
SOS1 son of sevenless homolog 1 (Drosophila)
SPHK1 sphingosine kinase 1
SPRR1A small proline-rich protein 1A
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
SPRY3 sprouty homolog 3 (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
SPTBN4 spectrin, beta, non-erythrocytic 4
SQSTM1 sequestosome 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRPK1 SRSF protein kinase 1
SSR1 signal sequence receptor, alpha
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STIP1 stress-induced phosphoprotein 1
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
SUSD1 sushi domain containing 1
SYK spleen tyrosine kinase
TBRG4 transforming growth factor beta regulator 4
TCF4 transcription factor 4
TEC tec protein tyrosine kinase
TFRC transferrin receptor
TGFA transforming growth factor, alpha
THEM6 thioesterase superfamily member 6
TIMM21 translocase of inner mitochondrial membrane 21 homolog (yeast)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TLN1 talin 1
TMEM33 transmembrane protein 33
TNFAIP2 tumor necrosis factor, alpha-induced protein 2
TNK2 tyrosine kinase, non-receptor, 2
TNS2 tensin 2
TNS3 tensin 3
TOB1 transducer of ERBB2, 1
TP53RK TP53 regulating kinase
TRIM24 tripartite motif containing 24
TRIM29 tripartite motif containing 29
TUBA1A tubulin, alpha 1a
TUBA4A tubulin, alpha 4a
TUBB tubulin, beta class I
TUFM Tu translation elongation factor, mitochondrial
TXK TXK tyrosine kinase
TXN thioredoxin
UBASH3B ubiquitin associated and SH3 domain containing B
UBB ubiquitin B
UBC ubiquitin C
UNC45B unc-45 homolog B (C. elegans)
USP2 ubiquitin specific peptidase 2
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
WASF1 WAS protein family, member 1
WASF2 WAS protein family, member 2
WASF3 WAS protein family, member 3
WASL Wiskott-Aldrich syndrome-like
XPO1 exportin 1
XPOT exportin, tRNA
XRN2 5'-3' exoribonuclease 2
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YTHDF1 YTH N(6)-methyladenosine RNA binding protein 1
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta
YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta
ZMYM2 zinc finger, MYM-type 2