ERBB2_druginhibition_6_GDS2139 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Kinase Perturbations
Category transcriptomics
Type kinase perturbation
Description kinase perturbation identified as [kinase gene symbol]_[perturbation]_[perturbation ID]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GDS2139
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Genes

600 genes differentially expressed following the ERBB2_druginhibition_6_GDS2139 kinase perturbation from the GEO Signatures of Differentially Expressed Genes for Kinase Perturbations dataset.

increased expression

Symbol Name Standardized Value
C3ORF17 chromosome 3 open reading frame 17 3.45732
IL17RA interleukin 17 receptor A 3.4343
LAMA1 laminin, alpha 1 3.21005
PER2 period circadian clock 2 3.11618
CTGF connective tissue growth factor 3.05627
NTSR2 neurotensin receptor 2 3.02585
CCR5 chemokine (C-C motif) receptor 5 (gene/pseudogene) 2.95584
PARP8 poly (ADP-ribose) polymerase family, member 8 2.93341
PLA2G5 phospholipase A2, group V 2.88093
ADAM20 ADAM metallopeptidase domain 20 2.87046
COQ10A coenzyme Q10 homolog A (S. cerevisiae) 2.87003
STK31 serine/threonine kinase 31 2.84994
CERK ceramide kinase 2.81369
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 2.79465
SNX4 sorting nexin 4 2.76145
MCM9 minichromosome maintenance complex component 9 2.75173
SCNN1G sodium channel, non voltage gated 1 gamma subunit 2.68823
MMP9 matrix metallopeptidase 9 2.68046
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 2.56722
DUSP12 dual specificity phosphatase 12 2.5411
CNTROB centrobin, centrosomal BRCA2 interacting protein 2.52522
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal 2.49193
NCR1 natural cytotoxicity triggering receptor 1 2.4906
C1ORF233 chromosome 1 open reading frame 233 2.46641
RBM47 RNA binding motif protein 47 2.45552
NPR1 natriuretic peptide receptor 1 2.44492
KCNIP4 Kv channel interacting protein 4 2.44431
CD40 CD40 molecule, TNF receptor superfamily member 5 2.44357
ABT1 activator of basal transcription 1 2.43252
FZD3 frizzled class receptor 3 2.42736
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 2.40269
GALNT10 polypeptide N-acetylgalactosaminyltransferase 10 2.38733
EEF1G eukaryotic translation elongation factor 1 gamma 2.38344
DOK5 docking protein 5 2.38289
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 2.37192
MICU1 mitochondrial calcium uptake 1 2.37115
FEZ1 fasciculation and elongation protein zeta 1 (zygin I) 2.3424
GRPR gastrin-releasing peptide receptor 2.32971
CHST12 carbohydrate (chondroitin 4) sulfotransferase 12 2.26806
HRH3 histamine receptor H3 2.24183
USP53 ubiquitin specific peptidase 53 2.24106
ZNF202 zinc finger protein 202 2.21713
TLK2 tousled-like kinase 2 2.21643
COX17 COX17 cytochrome c oxidase copper chaperone 2.2146
MAP6 microtubule-associated protein 6 2.20095
SLCO2A1 solute carrier organic anion transporter family, member 2A1 2.19999
SLC25A53 solute carrier family 25, member 53 2.19346
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1 2.1915
GCNT3 glucosaminyl (N-acetyl) transferase 3, mucin type 2.17533
TOR4A torsin family 4, member A 2.16209
AKIRIN2 akirin 2 2.15685
SNAP25 synaptosomal-associated protein, 25kDa 2.15082
ANXA2 annexin A2 2.10229
RIT2 Ras-like without CAAX 2 2.09315
NKAPL NFKB activating protein-like 2.09254
AASS aminoadipate-semialdehyde synthase 2.0799
DRD3 dopamine receptor D3 2.07674
CTLA4 cytotoxic T-lymphocyte-associated protein 4 2.07166
CD72 CD72 molecule 2.07162
FAM195B family with sequence similarity 195, member B 2.06252
CDC42EP3 CDC42 effector protein (Rho GTPase binding) 3 2.05807
NFAM1 NFAT activating protein with ITAM motif 1 2.05257
ZIC3 Zic family member 3 2.04734
MEST mesoderm specific transcript 2.03577
GK glycerol kinase 2.02941
ART4 ADP-ribosyltransferase 4 (Dombrock blood group) 2.02676
TDO2 tryptophan 2,3-dioxygenase 2.02158
APAF1 apoptotic peptidase activating factor 1 2.01878
GATA2 GATA binding protein 2 2.01238
SNAI2 snail family zinc finger 2 2.00202
SOX9 SRY (sex determining region Y)-box 9 2.00138
AP3S2 adaptor-related protein complex 3, sigma 2 subunit 1.99834
PHYKPL 5-phosphohydroxy-L-lysine phospho-lyase 1.99351
OLR1 oxidized low density lipoprotein (lectin-like) receptor 1 1.99262
CHCHD4 coiled-coil-helix-coiled-coil-helix domain containing 4 1.98804
HSF2 heat shock transcription factor 2 1.98656
RAI2 retinoic acid induced 2 1.98198
ZBTB21 zinc finger and BTB domain containing 21 1.97726
DDX4 DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 1.97349
TRIM16 tripartite motif containing 16 1.97231
SSNA1 Sjogren syndrome nuclear autoantigen 1 1.96967
TSNAXIP1 translin-associated factor X interacting protein 1 1.96462
CALCRL calcitonin receptor-like 1.96258
SLC39A13 solute carrier family 39 (zinc transporter), member 13 1.95765
BYSL bystin-like 1.95575
TRAF3IP2 TRAF3 interacting protein 2 1.93685
ACRBP acrosin binding protein 1.93493
SLC35A5 solute carrier family 35, member A5 1.93379
KIAA2022 KIAA2022 1.93293
ACY3 aminoacylase 3 1.93144
HOXA10 homeobox A10 1.91451
RAG1 recombination activating gene 1 1.91059
KIFC1 kinesin family member C1 1.90221
CDH10 cadherin 10, type 2 (T2-cadherin) 1.9001
MTSS1 metastasis suppressor 1 1.89841
GC group-specific component (vitamin D binding protein) 1.89636
SULT1C2 sulfotransferase family, cytosolic, 1C, member 2 1.88858
GFPT1 glutamine--fructose-6-phosphate transaminase 1 1.8838
GYS2 glycogen synthase 2 (liver) 1.88299
IL15RA interleukin 15 receptor, alpha 1.86688
THUMPD3 THUMP domain containing 3 1.84513
MAS1 MAS1 proto-oncogene, G protein-coupled receptor 1.84302
RPRD2 regulation of nuclear pre-mRNA domain containing 2 1.83705
PRSS37 protease, serine, 37 1.82913
VNN1 vanin 1 1.82641
LY6H lymphocyte antigen 6 complex, locus H 1.81254
ARHGAP29 Rho GTPase activating protein 29 1.80897
LRRC14 leucine rich repeat containing 14 1.80585
NFIA nuclear factor I/A 1.80549
FBXL12 F-box and leucine-rich repeat protein 12 1.8051
MYF5 myogenic factor 5 1.80224
SOX6 SRY (sex determining region Y)-box 6 1.79808
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11 1.79701
C11ORF52 chromosome 11 open reading frame 52 1.79198
SPTB spectrin, beta, erythrocytic 1.79143
RTP4 receptor (chemosensory) transporter protein 4 1.79025
SSTR1 somatostatin receptor 1 1.78275
NR2F2 nuclear receptor subfamily 2, group F, member 2 1.78203
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.78023
FAM120B family with sequence similarity 120B 1.77463
FAHD1 fumarylacetoacetate hydrolase domain containing 1 1.7712
C11ORF16 chromosome 11 open reading frame 16 1.74927
ST6GALNAC1 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 1.7484
TMUB1 transmembrane and ubiquitin-like domain containing 1 1.74421
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa 1.74409
TFPI2 tissue factor pathway inhibitor 2 1.74189
PAQR4 progestin and adipoQ receptor family member IV 1.74047
TMOD2 tropomodulin 2 (neuronal) 1.73986
ABCG8 ATP-binding cassette, sub-family G (WHITE), member 8 1.72634
EDN1 endothelin 1 1.72467
REM1 RAS (RAD and GEM)-like GTP-binding 1 1.72357
TXNDC11 thioredoxin domain containing 11 1.72176
IRGM immunity-related GTPase family, M 1.72051
PREB prolactin regulatory element binding 1.71508
LARP6 La ribonucleoprotein domain family, member 6 1.7124
AMPH amphiphysin 1.71162
ZFP36L2 ZFP36 ring finger protein-like 2 1.7102
TYK2 tyrosine kinase 2 1.70973
ANKRD13A ankyrin repeat domain 13A 1.70844
BMP2K BMP2 inducible kinase 1.70517
CYP4A11 cytochrome P450, family 4, subfamily A, polypeptide 11 1.70492
CIRH1A cirrhosis, autosomal recessive 1A (cirhin) 1.70473
CXCL12 chemokine (C-X-C motif) ligand 12 1.70308
SLC30A4 solute carrier family 30 (zinc transporter), member 4 1.68894
KCNJ14 potassium channel, inwardly rectifying subfamily J, member 14 1.68252
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 1.67879
PCP4 Purkinje cell protein 4 1.67679
CACNB4 calcium channel, voltage-dependent, beta 4 subunit 1.66943
PCDHB4 protocadherin beta 4 1.6692
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase 1.66472
SF3B4 splicing factor 3b, subunit 4, 49kDa 1.66325
ABCD1 ATP-binding cassette, sub-family D (ALD), member 1 1.6476
FIBP fibroblast growth factor (acidic) intracellular binding protein 1.64749
CADM3 cell adhesion molecule 3 1.64716
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5 1.6448
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase 1.64436
PRPH2 peripherin 2 (retinal degeneration, slow) 1.63948
GALNTL5 polypeptide N-acetylgalactosaminyltransferase-like 5 1.63903
TGFB2 transforming growth factor, beta 2 1.63828
TRAM1L1 translocation associated membrane protein 1-like 1 1.63645
CCDC86 coiled-coil domain containing 86 1.63276
NMNAT1 nicotinamide nucleotide adenylyltransferase 1 1.63118
PKNOX2 PBX/knotted 1 homeobox 2 1.62932
TMEM8C transmembrane protein 8C 1.62279
RAD51B RAD51 paralog B 1.61883
EFCAB14 EF-hand calcium binding domain 14 1.61656
HOXA1 homeobox A1 1.61202
SIX1 SIX homeobox 1 1.61044
HTRA3 HtrA serine peptidase 3 1.60889
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2 1.60822
SHISA2 shisa family member 2 1.60773
FAM161A family with sequence similarity 161, member A 1.60246
HOXA4 homeobox A4 1.59646
LRRTM2 leucine rich repeat transmembrane neuronal 2 1.59631
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 1.58986
CCDC91 coiled-coil domain containing 91 1.58485
GDF10 growth differentiation factor 10 1.58477
SOAT2 sterol O-acyltransferase 2 1.5801
EXT2 exostosin glycosyltransferase 2 1.5793
GRHL1 grainyhead-like 1 (Drosophila) 1.57575
IGFALS insulin-like growth factor binding protein, acid labile subunit 1.57512
CDCP1 CUB domain containing protein 1 1.56304
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 1.56229
C2CD2L C2CD2-like 1.56116
STK39 serine threonine kinase 39 1.55686
FBXO17 F-box protein 17 1.55406
KLHL26 kelch-like family member 26 1.55288
TUBA4A tubulin, alpha 4a 1.55246
SIGIRR single immunoglobulin and toll-interleukin 1 receptor (TIR) domain 1.55124
KCNK4 potassium channel, two pore domain subfamily K, member 4 1.54864
POLR3E polymerase (RNA) III (DNA directed) polypeptide E (80kD) 1.54855
HLA-DMB major histocompatibility complex, class II, DM beta 1.54693
FCER1A Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide 1.54379
CARF calcium responsive transcription factor 1.54149
HP haptoglobin 1.53927
CAMK2G calcium/calmodulin-dependent protein kinase II gamma 1.5375
APOB apolipoprotein B 1.53593
MBD1 methyl-CpG binding domain protein 1 1.53481
RSAD2 radical S-adenosyl methionine domain containing 2 1.53153
ANGPTL1 angiopoietin-like 1 1.52827
BTBD10 BTB (POZ) domain containing 10 1.52454
KAT7 K(lysine) acetyltransferase 7 1.51621
TDGF1 teratocarcinoma-derived growth factor 1 1.51588
DTD2 D-tyrosyl-tRNA deacylase 2 (putative) 1.51205
ATAD3A ATPase family, AAA domain containing 3A 1.51178
NDST2 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2 1.50812
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B 1.50716
SLC50A1 solute carrier family 50 (sugar efflux transporter), member 1 1.50454
EBF2 early B-cell factor 2 1.50251
SPATS2L spermatogenesis associated, serine-rich 2-like 1.50001
PTDSS1 phosphatidylserine synthase 1 1.49059
ALPK3 alpha-kinase 3 1.49056
JRK Jrk homolog (mouse) 1.48827
SRPK3 SRSF protein kinase 3 1.48785
ATP9B ATPase, class II, type 9B 1.48751
RIOK3 RIO kinase 3 1.48497
CDC42SE1 CDC42 small effector 1 1.4832
FGF2 fibroblast growth factor 2 (basic) 1.48197
FSTL3 follistatin-like 3 (secreted glycoprotein) 1.4791
RNF146 ring finger protein 146 1.47852
NPPA natriuretic peptide A 1.47193
BCL2L2 BCL2-like 2 1.47193
MFN1 mitofusin 1 1.46947
SIGLEC8 sialic acid binding Ig-like lectin 8 1.46888
TGM2 transglutaminase 2 1.46649
ADORA1 adenosine A1 receptor 1.46481
SPP1 secreted phosphoprotein 1 1.4641
ARL4C ADP-ribosylation factor-like 4C 1.46298
GREM1 gremlin 1, DAN family BMP antagonist 1.46259
INSL5 insulin-like 5 1.46196
MPO myeloperoxidase 1.46182
PTGDR prostaglandin D2 receptor (DP) 1.46108
RAP2B RAP2B, member of RAS oncogene family 1.45442
KRT5 keratin 5, type II 1.45233
LDLR low density lipoprotein receptor 1.45065
C10ORF54 chromosome 10 open reading frame 54 1.45025
CA5B carbonic anhydrase VB, mitochondrial 1.44291
GMPPB GDP-mannose pyrophosphorylase B 1.44185
ADRB1 adrenoceptor beta 1 1.44024
HEATR6 HEAT repeat containing 6 1.43986
PLA2G12A phospholipase A2, group XIIA 1.43752
ZBTB44 zinc finger and BTB domain containing 44 1.4356
SYNE4 spectrin repeat containing, nuclear envelope family member 4 1.43546
ATXN2 ataxin 2 1.43215
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2 1.42813
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 1.42731
VSNL1 visinin-like 1 1.42638
C5ORF22 chromosome 5 open reading frame 22 1.42221
B4GALT1 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 1.42177
IFI44L interferon-induced protein 44-like 1.42158
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5 1.41841
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6 1.41763
PNRC2 proline-rich nuclear receptor coactivator 2 1.41712
FLNB filamin B, beta 1.41662
CXCR3 chemokine (C-X-C motif) receptor 3 1.41557
IL12RB2 interleukin 12 receptor, beta 2 1.41485
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.4121
CST8 cystatin 8 (cystatin-related epididymal specific) 1.40943
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 1.40927
SALL4 spalt-like transcription factor 4 1.40688
NEUROD6 neuronal differentiation 6 1.40601
GMIP GEM interacting protein 1.40587
TSC22D4 TSC22 domain family, member 4 1.40363
CHRNB4 cholinergic receptor, nicotinic, beta 4 (neuronal) 1.4029
LPAR2 lysophosphatidic acid receptor 2 1.40278
CRELD1 cysteine-rich with EGF-like domains 1 1.40262
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) 1.40173
S100A6 S100 calcium binding protein A6 1.40155
T T, brachyury homolog (mouse) 1.39844
DNAJB9 DnaJ (Hsp40) homolog, subfamily B, member 9 1.39828
PCBP1 poly(rC) binding protein 1 1.39779
SLC39A9 solute carrier family 39, member 9 1.39706
RCL1 RNA terminal phosphate cyclase-like 1 1.39653
LIG3 ligase III, DNA, ATP-dependent 1.39347
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 1.39245
ISL2 ISL LIM homeobox 2 1.39192
ZFAND2A zinc finger, AN1-type domain 2A 1.39056
CAMK1D calcium/calmodulin-dependent protein kinase ID 1.38857
MYOC myocilin, trabecular meshwork inducible glucocorticoid response 1.38785
DHRS7B dehydrogenase/reductase (SDR family) member 7B 1.38713
LTK leukocyte receptor tyrosine kinase 1.38621
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3 1.38447
YAE1D1 Yae1 domain containing 1 1.37776
ZNF443 zinc finger protein 443 1.37391
ARHGAP4 Rho GTPase activating protein 4 1.37377
MADD MAP-kinase activating death domain 1.37224
RELL2 RELT-like 2 1.37165
PPRC1 peroxisome proliferator-activated receptor gamma, coactivator-related 1 1.36676
CD14 CD14 molecule 1.36659
CEP250 centrosomal protein 250kDa 1.3641
SYS1 Sys1 golgi trafficking protein 1.36296
DIABLO diablo, IAP-binding mitochondrial protein 1.36272
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.36204
RGS7 regulator of G-protein signaling 7 1.35931
MFAP1 microfibrillar-associated protein 1 1.35851
UBR3 ubiquitin protein ligase E3 component n-recognin 3 (putative) 1.35764
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 1.3569
RNF186 ring finger protein 186 1.35471
RGL1 ral guanine nucleotide dissociation stimulator-like 1 1.35344
MIOX myo-inositol oxygenase 1.35317

decreased expression

Symbol Name Standardized Value
FAM210B family with sequence similarity 210, member B -3.64661
FARSB phenylalanyl-tRNA synthetase, beta subunit -3.5232
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type -3.5022
INO80E INO80 complex subunit E -3.46528
RPL4 ribosomal protein L4 -3.42093
ANAPC16 anaphase promoting complex subunit 16 -3.32622
ZNF518B zinc finger protein 518B -3.31412
C17ORF85 chromosome 17 open reading frame 85 -3.28048
BRD3 bromodomain containing 3 -3.27904
CMTR2 cap methyltransferase 2 -3.23388
MYEOV2 myeloma overexpressed 2 -3.19609
AHI1 Abelson helper integration site 1 -3.1677
MTMR7 myotubularin related protein 7 -3.14536
SCN1A sodium channel, voltage gated, type I alpha subunit -3.05621
CRAT carnitine O-acetyltransferase -3.05438
SUB1 SUB1 homolog (S. cerevisiae) -3.02258
UTRN utrophin -2.8744
EFCAB2 EF-hand calcium binding domain 2 -2.85397
KBTBD4 kelch repeat and BTB (POZ) domain containing 4 -2.80844
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric -2.80399
KIF23 kinesin family member 23 -2.76128
ATOX1 antioxidant 1 copper chaperone -2.75835
ARSG arylsulfatase G -2.68104
POC5 POC5 centriolar protein -2.678
PTGR2 prostaglandin reductase 2 -2.67031
TPMT thiopurine S-methyltransferase -2.61931
SCN3A sodium channel, voltage gated, type III alpha subunit -2.61458
HOXD4 homeobox D4 -2.61032
GCDH glutaryl-CoA dehydrogenase -2.60376
RPS3 ribosomal protein S3 -2.58774
EXOC4 exocyst complex component 4 -2.56771
ANGPTL3 angiopoietin-like 3 -2.56013
TEX9 testis expressed 9 -2.55919
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -2.55652
WDR48 WD repeat domain 48 -2.54739
CCND1 cyclin D1 -2.54114
HABP4 hyaluronan binding protein 4 -2.5297
RAB6B RAB6B, member RAS oncogene family -2.51941
CLCN2 chloride channel, voltage-sensitive 2 -2.48808
TAF9 TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa -2.48684
PNOC prepronociceptin -2.48553
REPIN1 replication initiator 1 -2.47522
GTF2IRD1 GTF2I repeat domain containing 1 -2.47219
BTF3 basic transcription factor 3 -2.45233
HEY1 hes-related family bHLH transcription factor with YRPW motif 1 -2.45228
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) -2.44683
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) -2.43637
NRM nurim (nuclear envelope membrane protein) -2.42777
SNCAIP synuclein, alpha interacting protein -2.42436
SOCS4 suppressor of cytokine signaling 4 -2.42204
SCPEP1 serine carboxypeptidase 1 -2.41194
NIT1 nitrilase 1 -2.40879
CCDC85A coiled-coil domain containing 85A -2.40803
MYH3 myosin, heavy chain 3, skeletal muscle, embryonic -2.38979
ILKAP integrin-linked kinase-associated serine/threonine phosphatase -2.36889
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 -2.36533
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 -2.36463
CRYZL1 crystallin, zeta (quinone reductase)-like 1 -2.36162
RLIM ring finger protein, LIM domain interacting -2.35453
KIF2C kinesin family member 2C -2.35302
KDM3A lysine (K)-specific demethylase 3A -2.34585
RPS28 ribosomal protein S28 -2.34099
TERF2IP telomeric repeat binding factor 2, interacting protein -2.32626
SETD4 SET domain containing 4 -2.31855
WDR20 WD repeat domain 20 -2.31581
EIF3H eukaryotic translation initiation factor 3, subunit H -2.30938
STK24 serine/threonine kinase 24 -2.29689
RNASEH1 ribonuclease H1 -2.28645
AZIN1 antizyme inhibitor 1 -2.28624
JADE1 jade family PHD finger 1 -2.27748
RPL27A ribosomal protein L27a -2.27657
NOTUM notum pectinacetylesterase homolog (Drosophila) -2.26543
PIP5K1C phosphatidylinositol-4-phosphate 5-kinase, type I, gamma -2.26138
CBX1 chromobox homolog 1 -2.24753
DYX1C1 dyslexia susceptibility 1 candidate 1 -2.24721
MUTYH mutY homolog -2.24446
PI4KA phosphatidylinositol 4-kinase, catalytic, alpha -2.23722
IQSEC1 IQ motif and Sec7 domain 1 -2.23622
NRF1 nuclear respiratory factor 1 -2.23348
CCDC130 coiled-coil domain containing 130 -2.23239
RPL15 ribosomal protein L15 -2.23041
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -2.22906
MAP2K5 mitogen-activated protein kinase kinase 5 -2.22888
WISP1 WNT1 inducible signaling pathway protein 1 -2.22464
TP53RK TP53 regulating kinase -2.22384
GORASP1 golgi reassembly stacking protein 1, 65kDa -2.2217
CIB1 calcium and integrin binding 1 (calmyrin) -2.22051
UCP3 uncoupling protein 3 (mitochondrial, proton carrier) -2.21662
UBA2 ubiquitin-like modifier activating enzyme 2 -2.2134
PIP5KL1 phosphatidylinositol-4-phosphate 5-kinase-like 1 -2.21203
EFTUD2 elongation factor Tu GTP binding domain containing 2 -2.21006
E2F1 E2F transcription factor 1 -2.20772
RPL9 ribosomal protein L9 -2.19845
POFUT2 protein O-fucosyltransferase 2 -2.19616
RLBP1 retinaldehyde binding protein 1 -2.19567
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae) -2.19421
PIBF1 progesterone immunomodulatory binding factor 1 -2.1914
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 -2.19042
SCRT1 scratch family zinc finger 1 -2.18656
C1ORF123 chromosome 1 open reading frame 123 -2.1844
DUS3L dihydrouridine synthase 3-like (S. cerevisiae) -2.15967
PFDN5 prefoldin subunit 5 -2.15594
SGSH N-sulfoglucosamine sulfohydrolase -2.15327
MRPS36 mitochondrial ribosomal protein S36 -2.14998
SNX12 sorting nexin 12 -2.14817
MNT MAX network transcriptional repressor -2.14692
STRN4 striatin, calmodulin binding protein 4 -2.14461
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 -2.13605
GNMT glycine N-methyltransferase -2.12653
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 -2.12544
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2 -2.12173
C19ORF68 chromosome 19 open reading frame 68 -2.11868
LIME1 Lck interacting transmembrane adaptor 1 -2.11484
TRUB2 TruB pseudouridine (psi) synthase family member 2 -2.11468
LOC728392 uncharacterized LOC728392 -2.11304
ST5 suppression of tumorigenicity 5 -2.11094
LRR1 leucine rich repeat protein 1 -2.09794
CENPN centromere protein N -2.08077
SLC38A10 solute carrier family 38, member 10 -2.07954
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase -2.07647
UQCRB ubiquinol-cytochrome c reductase binding protein -2.0675
CHERP calcium homeostasis endoplasmic reticulum protein -2.0661
CDCA4 cell division cycle associated 4 -2.06489
PTGES3 prostaglandin E synthase 3 (cytosolic) -2.06465
RPS17 ribosomal protein S17 -2.06255
TTC13 tetratricopeptide repeat domain 13 -2.06193
CSGALNACT1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 -2.048
MRPS14 mitochondrial ribosomal protein S14 -2.04683
FBXW2 F-box and WD repeat domain containing 2 -2.04653
SEPHS1 selenophosphate synthetase 1 -2.04485
DCAF12 DDB1 and CUL4 associated factor 12 -2.04317
RAX retina and anterior neural fold homeobox -2.04007
TMEM141 transmembrane protein 141 -2.037
LAMC3 laminin, gamma 3 -2.033
C6ORF201 chromosome 6 open reading frame 201 -2.02824
OLIG2 oligodendrocyte lineage transcription factor 2 -2.02152
SKA2 spindle and kinetochore associated complex subunit 2 -2.02097
BRWD1 bromodomain and WD repeat domain containing 1 -2.02011
MUC5AC mucin 5AC, oligomeric mucus/gel-forming -2.018
LRRTM1 leucine rich repeat transmembrane neuronal 1 -2.01405
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae) -2.01192
RNF214 ring finger protein 214 -2.01024
MSX1 msh homeobox 1 -2.00265
RDH5 retinol dehydrogenase 5 (11-cis/9-cis) -1.99832
CERS4 ceramide synthase 4 -1.99586
MCM3 minichromosome maintenance complex component 3 -1.99411
DCTN5 dynactin 5 (p25) -1.98906
ATG12 autophagy related 12 -1.98784
ESPN espin -1.98554
TMEM135 transmembrane protein 135 -1.98454
COX6A1 cytochrome c oxidase subunit VIa polypeptide 1 -1.98369
HCFC1 host cell factor C1 -1.98067
CCDC53 coiled-coil domain containing 53 -1.97609
WDR82 WD repeat domain 82 -1.97528
ZNF616 zinc finger protein 616 -1.97288
NACA nascent polypeptide-associated complex alpha subunit -1.95851
HAAO 3-hydroxyanthranilate 3,4-dioxygenase -1.95773
DENND6A DENN/MADD domain containing 6A -1.95471
VPS26B vacuolar protein sorting 26 homolog B (S. pombe) -1.94981
RXRG retinoid X receptor, gamma -1.94709
DPYSL5 dihydropyrimidinase-like 5 -1.94667
SKA1 spindle and kinetochore associated complex subunit 1 -1.93684
FOXM1 forkhead box M1 -1.9348
RPLP0 ribosomal protein, large, P0 -1.93351
ZNF574 zinc finger protein 574 -1.92778
TMUB2 transmembrane and ubiquitin-like domain containing 2 -1.92233
ZNF275 zinc finger protein 275 -1.9218
MECOM MDS1 and EVI1 complex locus -1.91543
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta -1.91091
DENND2D DENN/MADD domain containing 2D -1.91058
CACNA2D3 calcium channel, voltage-dependent, alpha 2/delta subunit 3 -1.90929
TRIM33 tripartite motif containing 33 -1.90517
ZCCHC6 zinc finger, CCHC domain containing 6 -1.90391
STK11 serine/threonine kinase 11 -1.90345
EIF3E eukaryotic translation initiation factor 3, subunit E -1.9003
RGL2 ral guanine nucleotide dissociation stimulator-like 2 -1.89742
CHMP7 charged multivesicular body protein 7 -1.88682
FHL5 four and a half LIM domains 5 -1.8816
CNPY2 canopy FGF signaling regulator 2 -1.88093
SUGP1 SURP and G patch domain containing 1 -1.87959
XPA xeroderma pigmentosum, complementation group A -1.87828
DNLZ DNL-type zinc finger -1.87677
NFYA nuclear transcription factor Y, alpha -1.87644
NFIX nuclear factor I/X (CCAAT-binding transcription factor) -1.87254
THOC7 THO complex 7 -1.87199
BRCA1 breast cancer 1, early onset -1.86818
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome -1.86651
RAF1 Raf-1 proto-oncogene, serine/threonine kinase -1.86508
NICN1 nicolin 1 -1.86046
DTNB dystrobrevin, beta -1.85973
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B -1.85869
SIAH1 siah E3 ubiquitin protein ligase 1 -1.85795
ABCD4 ATP-binding cassette, sub-family D (ALD), member 4 -1.85724
COMMD4 COMM domain containing 4 -1.85642
SIDT2 SID1 transmembrane family, member 2 -1.85391
MGST3 microsomal glutathione S-transferase 3 -1.85321
DAG1 dystroglycan 1 (dystrophin-associated glycoprotein 1) -1.85115
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae) -1.85006
NLK nemo-like kinase -1.84636
EDN3 endothelin 3 -1.8422
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae) -1.83906
WBP4 WW domain binding protein 4 -1.83848
IFT140 intraflagellar transport 140 -1.83612
RBM4 RNA binding motif protein 4 -1.83556
HDAC6 histone deacetylase 6 -1.83228
DDX59 DEAD (Asp-Glu-Ala-Asp) box polypeptide 59 -1.82989
C12ORF57 chromosome 12 open reading frame 57 -1.82031
ASXL1 additional sex combs like transcriptional regulator 1 -1.81881
HDGFRP2 hepatoma-derived growth factor-related protein 2 -1.81781
C16ORF62 chromosome 16 open reading frame 62 -1.80954
USP45 ubiquitin specific peptidase 45 -1.8093
HMGB2 high mobility group box 2 -1.80403
FNBP1 formin binding protein 1 -1.8029
INTS1 integrator complex subunit 1 -1.80263
EFCC1 EF-hand and coiled-coil domain containing 1 -1.80217
MRPL38 mitochondrial ribosomal protein L38 -1.80108
TM7SF2 transmembrane 7 superfamily member 2 -1.79997
TRIO trio Rho guanine nucleotide exchange factor -1.79733
WAC WW domain containing adaptor with coiled-coil -1.79587
BANF1 barrier to autointegration factor 1 -1.79293
ANGPTL4 angiopoietin-like 4 -1.7889
TYW1 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae) -1.78648
SAP18 Sin3A-associated protein, 18kDa -1.7853
RAD51 RAD51 recombinase -1.77547
ZFP64 ZFP64 zinc finger protein -1.77456
PKP2 plakophilin 2 -1.77399
ZNF346 zinc finger protein 346 -1.77093
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) -1.76722
MLPH melanophilin -1.76452
RPL31 ribosomal protein L31 -1.76429
INCENP inner centromere protein antigens 135/155kDa -1.76377
WDR78 WD repeat domain 78 -1.76291
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein -1.76101
PDGFB platelet-derived growth factor beta polypeptide -1.75451
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -1.75435
RPS11 ribosomal protein S11 -1.75205
TEX11 testis expressed 11 -1.75082
ATPAF2 ATP synthase mitochondrial F1 complex assembly factor 2 -1.75076
TPGS2 tubulin polyglutamylase complex subunit 2 -1.75073
NMRK1 nicotinamide riboside kinase 1 -1.7487
TCTN2 tectonic family member 2 -1.74575
PASK PAS domain containing serine/threonine kinase -1.74555
CHN2 chimerin 2 -1.74412
NT5C3B 5'-nucleotidase, cytosolic IIIB -1.74372
GPR153 G protein-coupled receptor 153 -1.74076
COL4A5 collagen, type IV, alpha 5 -1.73916
CEMIP cell migration inducing protein, hyaluronan binding -1.7387
ANXA10 annexin A10 -1.73659
KATNA1 katanin p60 (ATPase containing) subunit A 1 -1.73497
HMGXB4 HMG box domain containing 4 -1.73363
WWC2 WW and C2 domain containing 2 -1.73188
CRY1 cryptochrome circadian clock 1 -1.73082
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila) -1.72758
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 -1.72405
RAPGEF4 Rap guanine nucleotide exchange factor (GEF) 4 -1.72381
ATPIF1 ATPase inhibitory factor 1 -1.72366
LCK LCK proto-oncogene, Src family tyrosine kinase -1.7228
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5 -1.7226
PYGO2 pygopus family PHD finger 2 -1.71764
FKBP1B FK506 binding protein 1B, 12.6 kDa -1.71564
BBC3 BCL2 binding component 3 -1.7135
EN2 engrailed homeobox 2 -1.7132
HOXA5 homeobox A5 -1.71037
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) -1.70685
WDR33 WD repeat domain 33 -1.70583
FABP2 fatty acid binding protein 2, intestinal -1.70353
SPPL2B signal peptide peptidase like 2B -1.7001
PURG purine-rich element binding protein G -1.69894
TOR3A torsin family 3, member A -1.69851
PER3 period circadian clock 3 -1.69669
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae) -1.69579
WNK2 WNK lysine deficient protein kinase 2 -1.69283
SLC25A14 solute carrier family 25 (mitochondrial carrier, brain), member 14 -1.69145
KIFAP3 kinesin-associated protein 3 -1.68448
HNRNPK heterogeneous nuclear ribonucleoprotein K -1.68408
EIF4E2 eukaryotic translation initiation factor 4E family member 2 -1.68406
GFRA3 GDNF family receptor alpha 3 -1.68341
TGIF2 TGFB-induced factor homeobox 2 -1.6815
CPN2 carboxypeptidase N, polypeptide 2 -1.6779
TGDS TDP-glucose 4,6-dehydratase -1.67754
GPR34 G protein-coupled receptor 34 -1.67556
NAA40 N(alpha)-acetyltransferase 40, NatD catalytic subunit -1.67038
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -1.66984
SEC61B Sec61 beta subunit -1.66765
CDH8 cadherin 8, type 2 -1.66614
EARS2 glutamyl-tRNA synthetase 2, mitochondrial -1.6644
RNMTL1 RNA methyltransferase like 1 -1.66304
C1ORF159 chromosome 1 open reading frame 159 -1.66271
RS1 retinoschisin 1 -1.66263
NTPCR nucleoside-triphosphatase, cancer-related -1.66231
AFP alpha-fetoprotein -1.65779
STAU1 staufen double-stranded RNA binding protein 1 -1.65059
PCDHB15 protocadherin beta 15 -1.6476
RPS7 ribosomal protein S7 -1.64259
ATP4A ATPase, H+/K+ exchanging, alpha polypeptide -1.6385
FAM213A family with sequence similarity 213, member A -1.63514
CLCC1 chloride channel CLIC-like 1 -1.63426
RPLP2 ribosomal protein, large, P2 -1.6289
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) -1.62867
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) -1.6251