ERBB3 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description erb-b2 receptor tyrosine kinase 3|This gene encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors. Alternate transcriptional splice variants encoding different isoforms have been characterized. One isoform lacks the intermembrane region and is secreted outside the cell. This form acts to modulate the activity of the membrane-bound form. Additional splice variants have also been reported, but they have not been thoroughly characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2065)
External Link http://www.ncbi.nlm.nih.gov/gene/2065
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785 interacting proteins for ERBB3 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
ABI1 abl-interactor 1
ABI2 abl-interactor 2
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ABR active BCR-related
ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2
ACSF2 acyl-CoA synthetase family member 2
ACTA1 actin, alpha 1, skeletal muscle
ACTA2 actin, alpha 2, smooth muscle, aorta
ACTB actin, beta
ACTBL2 actin, beta-like 2
ACTC1 actin, alpha, cardiac muscle 1
ACTG1 actin gamma 1
ACTG2 actin, gamma 2, smooth muscle, enteric
ACTR2 ARP2 actin-related protein 2 homolog (yeast)
ADRM1 adhesion regulating molecule 1
AGK acylglycerol kinase
AGTR2 angiotensin II receptor, type 2
AIFM1 apoptosis-inducing factor, mitochondrion-associated, 1
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
ANAPC7 anaphase promoting complex subunit 7
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANXA2 annexin A2
ANXA6 annexin A6
ANXA9 annexin A9
AP1M2 adaptor-related protein complex 1, mu 2 subunit
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
AP2A1 adaptor-related protein complex 2, alpha 1 subunit
AP2A2 adaptor-related protein complex 2, alpha 2 subunit
AP2B1 adaptor-related protein complex 2, beta 1 subunit
AP2M1 adaptor-related protein complex 2, mu 1 subunit
AP3B1 adaptor-related protein complex 3, beta 1 subunit
AP3D1 adaptor-related protein complex 3, delta 1 subunit
AP3M1 adaptor-related protein complex 3, mu 1 subunit
AP3S1 adaptor-related protein complex 3, sigma 1 subunit
APPL2 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
ARAF A-Raf proto-oncogene, serine/threonine kinase
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARCN1 archain 1
AREG amphiregulin
ARF6 ADP-ribosylation factor 6
ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
ARFGEF2 ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
ARFRP1 ADP-ribosylation factor related protein 1
ARHGAP1 Rho GTPase activating protein 1
ARHGAP17 Rho GTPase activating protein 17
ARHGAP18 Rho GTPase activating protein 18
ARHGAP8 Rho GTPase activating protein 8
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARL15 ADP-ribosylation factor-like 15
ARL2 ADP-ribosylation factor-like 2
ARL5A ADP-ribosylation factor-like 5A
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1
ARL8B ADP-ribosylation factor-like 8B
ATG3 autophagy related 3
ATP6V0C ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
ATP6V1B2 ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2
ATP6V1C2 ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C2
ATP6V1D ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H
ATR ATR serine/threonine kinase
B2M beta-2-microglobulin
BAIAP2 BAI1-associated protein 2
BCAP31 B-cell receptor-associated protein 31
BCAR3 breast cancer anti-estrogen resistance 3
BCR breakpoint cluster region
BIN1 bridging integrator 1
BLOC1S1 biogenesis of lysosomal organelles complex-1, subunit 1
BLOC1S2 biogenesis of lysosomal organelles complex-1, subunit 2
BLOC1S4 biogenesis of lysosomal organelles complex-1, subunit 4, cappuccino
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit
BTC betacellulin
BTK Bruton agammaglobulinemia tyrosine kinase
CAB39 calcium binding protein 39
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALR calreticulin
CAMK2A calcium/calmodulin-dependent protein kinase II alpha
CANX calnexin
CASK calcium/calmodulin-dependent serine protein kinase (MAGUK family)
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CBLB Cbl proto-oncogene B, E3 ubiquitin protein ligase
CBLC Cbl proto-oncogene C, E3 ubiquitin protein ligase
CD247 CD247 molecule
CD28 CD28 molecule
CD3G CD3g molecule, gamma (CD3-TCR complex)
CD80 CD80 molecule
CD82 CD82 molecule
CD86 CD86 molecule
CDC23 cell division cycle 23
CDC37 cell division cycle 37
CDC42 cell division cycle 42
CDC42BPB CDC42 binding protein kinase beta (DMPK-like)
CDC42BPG CDC42 binding protein kinase gamma (DMPK-like)
CDC42SE2 CDC42 small effector 2
CDH1 cadherin 1, type 1, E-cadherin (epithelial)
CDH10 cadherin 10, type 2 (T2-cadherin)
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast)
CDH12 cadherin 12, type 2 (N-cadherin 2)
CDH13 cadherin 13
CDH15 cadherin 15, type 1, M-cadherin (myotubule)
CDH16 cadherin 16, KSP-cadherin
CDH17 cadherin 17, LI cadherin (liver-intestine)
CDH18 cadherin 18, type 2
CDH19 cadherin 19, type 2
CDH2 cadherin 2, type 1, N-cadherin (neuronal)
CDH20 cadherin 20, type 2
CDH22 cadherin 22, type 2
CDH23 cadherin-related 23
CDH24 cadherin 24, type 2
CDH3 cadherin 3, type 1, P-cadherin (placental)
CDH4 cadherin 4, type 1, R-cadherin (retinal)
CDH5 cadherin 5, type 2 (vascular endothelium)
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDH7 cadherin 7, type 2
CDH8 cadherin 8, type 2
CDH9 cadherin 9, type 2 (T1-cadherin)
CDHR1 cadherin-related family member 1
CDHR2 cadherin-related family member 2
CDIPT CDP-diacylglycerol--inositol 3-phosphatidyltransferase
CDK1 cyclin-dependent kinase 1
CDK11A cyclin-dependent kinase 11A
CDK5 cyclin-dependent kinase 5
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CELSR3 cadherin, EGF LAG seven-pass G-type receptor 3
CHEK1 checkpoint kinase 1
CHMP6 charged multivesicular body protein 6
CHN2 chimerin 2
CHP1 calcineurin-like EF-hand protein 1
CIB1 calcium and integrin binding 1 (calmyrin)
CISD2 CDGSH iron sulfur domain 2
CKAP5 cytoskeleton associated protein 5
CLASP2 cytoplasmic linker associated protein 2
CLCN7 chloride channel, voltage-sensitive 7
CLN5 ceroid-lipofuscinosis, neuronal 5
CLPB ClpB homolog, mitochondrial AAA ATPase chaperonin
CLTA clathrin, light chain A
CNTRL centriolin
COG3 component of oligomeric golgi complex 3
COG4 component of oligomeric golgi complex 4
COG5 component of oligomeric golgi complex 5
COPB1 coatomer protein complex, subunit beta 1
COPB2 coatomer protein complex, subunit beta 2 (beta prime)
COPE coatomer protein complex, subunit epsilon
COPZ1 coatomer protein complex, subunit zeta 1
CPLX1 complexin 1
CPSF6 cleavage and polyadenylation specific factor 6, 68kDa
CRK v-crk avian sarcoma virus CT10 oncogene homolog
CRKL v-crk avian sarcoma virus CT10 oncogene homolog-like
CSK c-src tyrosine kinase
CSNK1A1 casein kinase 1, alpha 1
CSNK1D casein kinase 1, delta
CSNK2A2 casein kinase 2, alpha prime polypeptide
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CTSA cathepsin A
CUX1 cut-like homeobox 1
CYFIP2 cytoplasmic FMR1 interacting protein 2
DAB1 Dab, reelin signal transducer, homolog 1 (Drosophila)
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DCHS1 dachsous cadherin-related 1
DCTN2 dynactin 2 (p50)
DGKQ diacylglycerol kinase, theta 110kDa
DIAPH1 diaphanous-related formin 1
DNAJA1 DnaJ (Hsp40) homolog, subfamily A, member 1
DNAJB11 DnaJ (Hsp40) homolog, subfamily B, member 11
DNM1L dynamin 1-like
DOCK1 dedicator of cytokinesis 1
DOCK5 dedicator of cytokinesis 5
DOCK7 dedicator of cytokinesis 7
DOPEY2 dopey family member 2
DTNBP1 dystrobrevin binding protein 1
DUSP3 dual specificity phosphatase 3
DYNC1I2 dynein, cytoplasmic 1, intermediate chain 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYNC1LI2 dynein, cytoplasmic 1, light intermediate chain 2
DYNLL1 dynein, light chain, LC8-type 1
DYNLRB1 dynein, light chain, roadblock-type 1
ECSIT ECSIT signalling integrator
EGF epidermal growth factor
EGFR epidermal growth factor receptor
EGR1 early growth response 1
EHD1 EH-domain containing 1
EHD4 EH-domain containing 4
ELMO3 engulfment and cell motility 3
EPB41L2 erythrocyte membrane protein band 4.1-like 2
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHB2 EPH receptor B2
ERBB2 erb-b2 receptor tyrosine kinase 2
ERBB2IP erbb2 interacting protein
ERBB4 erb-b2 receptor tyrosine kinase 4
EREG epiregulin
ERGIC1 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
ERGIC2 ERGIC and golgi 2
ERLIN2 ER lipid raft associated 2
ERRFI1 ERBB receptor feedback inhibitor 1
EXOC1 exocyst complex component 1
EXOC2 exocyst complex component 2
EXOC3 exocyst complex component 3
EXOC4 exocyst complex component 4
EXOC5 exocyst complex component 5
EXOC6 exocyst complex component 6
EXOC7 exocyst complex component 7
EXOC8 exocyst complex component 8
EXPH5 exophilin 5
FAM129B family with sequence similarity 129, member B
FAT1 FAT atypical cadherin 1
FAT2 FAT atypical cadherin 2
FAT3 FAT atypical cadherin 3
FCGR1A Fc fragment of IgG, high affinity Ia, receptor (CD64)
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32)
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
FER fer (fps/fes related) tyrosine kinase
FERMT1 fermitin family member 1
FGD3 FYVE, RhoGEF and PH domain containing 3
FGD4 FYVE, RhoGEF and PH domain containing 4
FGF1 fibroblast growth factor 1 (acidic)
FGF10 fibroblast growth factor 10
FGF16 fibroblast growth factor 16
FGF17 fibroblast growth factor 17
FGF18 fibroblast growth factor 18
FGF19 fibroblast growth factor 19
FGF2 fibroblast growth factor 2 (basic)
FGF20 fibroblast growth factor 20
FGF22 fibroblast growth factor 22
FGF23 fibroblast growth factor 23
FGF3 fibroblast growth factor 3
FGF4 fibroblast growth factor 4
FGF5 fibroblast growth factor 5
FGF6 fibroblast growth factor 6
FGF7 fibroblast growth factor 7
FGF8 fibroblast growth factor 8 (androgen-induced)
FGF9 fibroblast growth factor 9
FGFR1 fibroblast growth factor receptor 1
FGFR1OP FGFR1 oncogene partner
FGFR1OP2 FGFR1 oncogene partner 2
FGFR2 fibroblast growth factor receptor 2
FGFR3 fibroblast growth factor receptor 3
FGFR4 fibroblast growth factor receptor 4
FIG4 FIG4 phosphoinositide 5-phosphatase
FKBP1A FK506 binding protein 1A, 12kDa
FLII flightless I homolog (Drosophila)
FLNA filamin A, alpha
FLYWCH1 FLYWCH-type zinc finger 1
FNBP1L formin binding protein 1-like
FYN FYN proto-oncogene, Src family tyrosine kinase
GAB1 GRB2-associated binding protein 1
GAB2 GRB2-associated binding protein 2
GADD45GIP1 growth arrest and DNA-damage-inducible, gamma interacting protein 1
GALC galactosylceramidase
GAPVD1 GTPase activating protein and VPS9 domains 1
GBA glucosidase, beta, acid
GBF1 golgi brefeldin A resistant guanine nucleotide exchange factor 1
GDI2 GDP dissociation inhibitor 2
GM2A GM2 ganglioside activator
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GNAQ guanine nucleotide binding protein (G protein), q polypeptide
GOLGA7 golgin A7
GOLIM4 golgi integral membrane protein 4
GOLPH3 golgi phosphoprotein 3 (coat-protein)
GOLPH3L golgi phosphoprotein 3-like
GOLT1B golgi transport 1B
GOPC golgi-associated PDZ and coiled-coil motif containing
GOSR1 golgi SNAP receptor complex member 1
GOSR2 golgi SNAP receptor complex member 2
GPRC5A G protein-coupled receptor, class C, group 5, member A
GRAP2 GRB2-related adaptor protein 2
GRB2 growth factor receptor-bound protein 2
GRB7 growth factor receptor-bound protein 7
GRTP1 growth hormone regulated TBC protein 1
GSK3B glycogen synthase kinase 3 beta
GTPBP1 GTP binding protein 1
HAUS1 HAUS augmin-like complex, subunit 1
HAUS3 HAUS augmin-like complex, subunit 3
HAX1 HCLS1 associated protein X-1
HBEGF heparin-binding EGF-like growth factor
HCK HCK proto-oncogene, Src family tyrosine kinase
HDAC6 histone deacetylase 6
HGS hepatocyte growth factor-regulated tyrosine kinase substrate
HIP1 huntingtin interacting protein 1
HIP1R huntingtin interacting protein 1 related
HLA-A major histocompatibility complex, class I, A
HLA-B major histocompatibility complex, class I, B
HNF4A hepatocyte nuclear factor 4, alpha
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPH2 heterogeneous nuclear ribonucleoprotein H2 (H')
HOOK1 hook microtubule-tethering protein 1
HOOK2 hook microtubule-tethering protein 2
HRAS Harvey rat sarcoma viral oncogene homolog
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
HTT huntingtin
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker)
IGHG3 immunoglobulin heavy constant gamma 3 (G3m marker)
IGHG4 immunoglobulin heavy constant gamma 4 (G4m marker)
IGKC immunoglobulin kappa constant
IGKV1-5 immunoglobulin kappa variable 1-5
IGKV4-1 immunoglobulin kappa variable 4-1
IGLC1 immunoglobulin lambda constant 1 (Mcg marker)
IGLC2 immunoglobulin lambda constant 2 (Kern-Oz- marker)
IGLC3 immunoglobulin lambda constant 3 (Kern-Oz+ marker)
IGLC6 immunoglobulin lambda constant 6 (Kern+Oz- marker, gene/pseudogene)
IL6ST interleukin 6 signal transducer
ILK integrin-linked kinase
IRF9 interferon regulatory factor 9
IST1 increased sodium tolerance 1 homolog (yeast)
ITK IL2-inducible T-cell kinase
ITPK1 inositol-tetrakisphosphate 1-kinase
JAK1 Janus kinase 1
JAK2 Janus kinase 2
JAK3 Janus kinase 3
KHDRBS1 KH domain containing, RNA binding, signal transduction associated 1
KIAA0196 KIAA0196
KIAA1033 KIAA1033
KIF11 kinesin family member 11
KIF5B kinesin family member 5B
KL klotho
KLB klotho beta
KLC1 kinesin light chain 1
KLC2 kinesin light chain 2
KLC4 kinesin light chain 4
KNTC1 kinetochore associated 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LAMP1 lysosomal-associated membrane protein 1
LAMP2 lysosomal-associated membrane protein 2
LAMTOR3 late endosomal/lysosomal adaptor, MAPK and MTOR activator 3
LANCL1 LanC lantibiotic synthetase component C-like 1 (bacterial)
LAT linker for activation of T cells
LAT2 linker for activation of T cells family, member 2
LCK LCK proto-oncogene, Src family tyrosine kinase
LCP2 lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
LEMD3 LEM domain containing 3
LIN7C lin-7 homolog C (C. elegans)
LRBA LPS-responsive vesicle trafficking, beach and anchor containing
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LRPPRC leucine-rich pentatricopeptide repeat containing
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LSG1 large 60S subunit nuclear export GTPase 1
LYN LYN proto-oncogene, Src family tyrosine kinase
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAP1S microtubule-associated protein 1S
MAP2K1 mitogen-activated protein kinase kinase 1
MAP2K2 mitogen-activated protein kinase kinase 2
MAP2K3 mitogen-activated protein kinase kinase 3
MAP2K4 mitogen-activated protein kinase kinase 4
MAPK1 mitogen-activated protein kinase 1
MAPK13 mitogen-activated protein kinase 13
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPKAPK2 mitogen-activated protein kinase-activated protein kinase 2
MASP1 mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)
MCM2 minichromosome maintenance complex component 2
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MOB1B MOB kinase activator 1B
MON2 MON2 homolog (S. cerevisiae)
MOSPD2 motile sperm domain containing 2
MRAS muscle RAS oncogene homolog
MRPS14 mitochondrial ribosomal protein S14
MRPS17 mitochondrial ribosomal protein S17
MRPS18B mitochondrial ribosomal protein S18B
MRPS22 mitochondrial ribosomal protein S22
MRPS23 mitochondrial ribosomal protein S23
MRPS25 mitochondrial ribosomal protein S25
MRPS26 mitochondrial ribosomal protein S26
MRPS27 mitochondrial ribosomal protein S27
MRPS28 mitochondrial ribosomal protein S28
MRPS34 mitochondrial ribosomal protein S34
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MUC1 mucin 1, cell surface associated
MVB12A multivesicular body subunit 12A
MVP major vault protein
MYO18A myosin XVIIIA
MYO6 myosin VI
MYOF myoferlin
NAAA N-acylethanolamine acid amidase
NAGLU N-acetylglucosaminidase, alpha
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma
NCAPG non-SMC condensin I complex, subunit G
NCK1 NCK adaptor protein 1
NCK2 NCK adaptor protein 2
NCKAP1 NCK-associated protein 1
NCSTN nicastrin
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase
NEK6 NIMA-related kinase 6
NEK9 NIMA-related kinase 9
NEU1 sialidase 1 (lysosomal sialidase)
NF1 neurofibromin 1
NF2 neurofibromin 2 (merlin)
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC3 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
NKIRAS2 NFKB inhibitor interacting Ras-like 2
NOS3 nitric oxide synthase 3 (endothelial cell)
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRG1 neuregulin 1
NRG2 neuregulin 2
NRG3 neuregulin 3
NRG4 neuregulin 4
NSF N-ethylmaleimide-sensitive factor
NUDC nudC nuclear distribution protein
ODF2L outer dense fiber of sperm tails 2-like
OSBP oxysterol binding protein
OSBPL11 oxysterol binding protein-like 11
OSBPL3 oxysterol binding protein-like 3
OSBPL8 oxysterol binding protein-like 8
OXSR1 oxidative stress responsive 1
PA2G4 proliferation-associated 2G4, 38kDa
PACSIN2 protein kinase C and casein kinase substrate in neurons 2
PCDH1 protocadherin 1
PCDH10 protocadherin 10
PCDH11X protocadherin 11 X-linked
PCDH11Y protocadherin 11 Y-linked
PCDH12 protocadherin 12
PCDH15 protocadherin-related 15
PCDH18 protocadherin 18
PCDH19 protocadherin 19
PCDH20 protocadherin 20
PCDH7 protocadherin 7
PCDH8 protocadherin 8
PCDH9 protocadherin 9
PCDHA1 protocadherin alpha 1
PCDHA10 protocadherin alpha 10
PCDHA11 protocadherin alpha 11
PCDHA12 protocadherin alpha 12
PCDHA13 protocadherin alpha 13
PCDHA2 protocadherin alpha 2
PCDHA3 protocadherin alpha 3
PCDHA4 protocadherin alpha 4
PCDHA5 protocadherin alpha 5
PCDHA6 protocadherin alpha 6
PCDHA7 protocadherin alpha 7
PCDHA8 protocadherin alpha 8
PCDHA9 protocadherin alpha 9
PCDHAC1 protocadherin alpha subfamily C, 1
PCDHAC2 protocadherin alpha subfamily C, 2
PCDHB1 protocadherin beta 1
PCDHB10 protocadherin beta 10
PCDHB11 protocadherin beta 11
PCDHB12 protocadherin beta 12
PCDHB13 protocadherin beta 13
PCDHB14 protocadherin beta 14
PCDHB15 protocadherin beta 15
PCDHB16 protocadherin beta 16
PCDHB2 protocadherin beta 2
PCDHB3 protocadherin beta 3
PCDHB4 protocadherin beta 4
PCDHB5 protocadherin beta 5
PCDHB6 protocadherin beta 6
PCDHB7 protocadherin beta 7
PCDHB8 protocadherin beta 8
PCDHGA1 protocadherin gamma subfamily A, 1
PCDHGA10 protocadherin gamma subfamily A, 10
PCDHGA11 protocadherin gamma subfamily A, 11
PCDHGA12 protocadherin gamma subfamily A, 12
PCDHGA2 protocadherin gamma subfamily A, 2
PCDHGA3 protocadherin gamma subfamily A, 3
PCDHGA5 protocadherin gamma subfamily A, 5
PCDHGA6 protocadherin gamma subfamily A, 6
PCDHGA7 protocadherin gamma subfamily A, 7
PCDHGA8 protocadherin gamma subfamily A, 8
PCDHGB1 protocadherin gamma subfamily B, 1
PCDHGB2 protocadherin gamma subfamily B, 2
PCDHGB4 protocadherin gamma subfamily B, 4
PCDHGB6 protocadherin gamma subfamily B, 6
PCDHGB7 protocadherin gamma subfamily B, 7
PCDHGC3 protocadherin gamma subfamily C, 3
PCDHGC4 protocadherin gamma subfamily C, 4
PCDHGC5 protocadherin gamma subfamily C, 5
PCTP phosphatidylcholine transfer protein
PCYOX1 prenylcysteine oxidase 1
PDCD4 programmed cell death 4 (neoplastic transformation inhibitor)
PDPK1 3-phosphoinositide dependent protein kinase 1
PDS5A PDS5 cohesin associated factor A
PDS5B PDS5 cohesin associated factor B
PDZD8 PDZ domain containing 8
PGAM5 phosphoglycerate mutase family member 5
PHLDA1 pleckstrin homology-like domain, family A, member 1
PHLDA2 pleckstrin homology-like domain, family A, member 2
PHLDA3 pleckstrin homology-like domain, family A, member 3
PICK1 protein interacting with PRKCA 1
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
PIK3R4 phosphoinositide-3-kinase, regulatory subunit 4
PITPNA phosphatidylinositol transfer protein, alpha
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PLCG1 phospholipase C, gamma 1
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLEK2 pleckstrin 2
PLEKHA1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2
PLIN3 perilipin 3
PMF1 polyamine-modulated factor 1
PON2 paraoxonase 2
POTEKP POTE ankyrin domain family, member K, pseudogene
PPM1B protein phosphatase, Mg2+/Mn2+ dependent, 1B
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP2R1B protein phosphatase 2, regulatory subunit A, beta
PPP2R2A protein phosphatase 2, regulatory subunit B, alpha
PPP3CB protein phosphatase 3, catalytic subunit, beta isozyme
PPT1 palmitoyl-protein thioesterase 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKAB1 protein kinase, AMP-activated, beta 1 non-catalytic subunit
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha
PRKCA protein kinase C, alpha
PRKCB protein kinase C, beta
PRKCD protein kinase C, delta
PRKCE protein kinase C, epsilon
PRKCG protein kinase C, gamma
PRKCH protein kinase C, eta
PRKCI protein kinase C, iota
PRKCQ protein kinase C, theta
PRKCZ protein kinase C, zeta
PRKD1 protein kinase D1
PRKD2 protein kinase D2
PRKD3 protein kinase D3
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSAP prosaposin
PSEN1 presenilin 1
PTCD3 pentatricopeptide repeat domain 3
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTK2 protein tyrosine kinase 2
PTK2B protein tyrosine kinase 2 beta
PTK6 protein tyrosine kinase 6
PTP4A1 protein tyrosine phosphatase type IVA, member 1
PTPN1 protein tyrosine phosphatase, non-receptor type 1
PTPN11 protein tyrosine phosphatase, non-receptor type 11
PTPN6 protein tyrosine phosphatase, non-receptor type 6
PTPN9 protein tyrosine phosphatase, non-receptor type 9
RAB13 RAB13, member RAS oncogene family
RAB18 RAB18, member RAS oncogene family
RAB1A RAB1A, member RAS oncogene family
RAB1B RAB1B, member RAS oncogene family
RAB20 RAB20, member RAS oncogene family
RAB21 RAB21, member RAS oncogene family
RAB25 RAB25, member RAS oncogene family
RAB2A RAB2A, member RAS oncogene family
RAB35 RAB35, member RAS oncogene family
RAB3GAP2 RAB3 GTPase activating protein subunit 2 (non-catalytic)
RAB43 RAB43, member RAS oncogene family
RAB5A RAB5A, member RAS oncogene family
RAB5B RAB5B, member RAS oncogene family
RAB7A RAB7A, member RAS oncogene family
RAB8A RAB8A, member RAS oncogene family
RAB9A RAB9A, member RAS oncogene family
RABL2A RAB, member of RAS oncogene family-like 2A
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
RAE1 ribonucleic acid export 1
RALA v-ral simian leukemia viral oncogene homolog A (ras related)
RALB v-ral simian leukemia viral oncogene homolog B
RANBP1 RAN binding protein 1
RANGAP1 Ran GTPase activating protein 1
RAP1A RAP1A, member of RAS oncogene family
RAP1GDS1 RAP1, GTP-GDP dissociation stimulator 1
RAP2B RAP2B, member of RAS oncogene family
RASA1 RAS p21 protein activator (GTPase activating protein) 1
RASA4 RAS p21 protein activator 4
RASGRP2 RAS guanyl releasing protein 2 (calcium and DAG-regulated)
RB1 retinoblastoma 1
RBX1 ring-box 1, E3 ubiquitin protein ligase
REPS1 RALBP1 associated Eps domain containing 1
RGS4 regulator of G-protein signaling 4
RHEB Ras homolog enriched in brain
RHOA ras homolog family member A
RHOF ras homolog family member F (in filopodia)
RHOG ras homolog family member G
RHOT1 ras homolog family member T1
RHOT2 ras homolog family member T2
RIC8A RIC8 guanine nucleotide exchange factor A
RIN1 Ras and Rab interactor 1
RINT1 RAD50 interactor 1
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
ROCK1 Rho-associated, coiled-coil containing protein kinase 1
ROR1 receptor tyrosine kinase-like orphan receptor 1
RPN1 ribophorin I
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA3 ribosomal protein S6 kinase, 90kDa, polypeptide 3
RPS6KA4 ribosomal protein S6 kinase, 90kDa, polypeptide 4
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RRAS related RAS viral (r-ras) oncogene homolog
RRAS2 related RAS viral (r-ras) oncogene homolog 2
RSU1 Ras suppressor protein 1
RUFY1 RUN and FYVE domain containing 1
S100A10 S100 calcium binding protein A10
SACM1L SAC1 suppressor of actin mutations 1-like (yeast)
SCAMP1 secretory carrier membrane protein 1
SCAMP2 secretory carrier membrane protein 2
SCAMP3 secretory carrier membrane protein 3
SCAMP4 secretory carrier membrane protein 4
SCARB2 scavenger receptor class B, member 2
SCFD2 sec1 family domain containing 2
SCYL1 SCY1-like 1 (S. cerevisiae)
SDF4 stromal cell derived factor 4
SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) (gene/pseudogene)
SEC31A SEC31 homolog A (S. cerevisiae)
SEC61A1 Sec61 alpha 1 subunit (S. cerevisiae)
SEC61B Sec61 beta subunit
SEC61G Sec61 gamma subunit
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SELENBP1 selenium binding protein 1
SEPT10 septin 10
SEPT11 septin 11
SEPT2 septin 2
SEPT7 septin 7
SEPT8 septin 8
SEPT9 septin 9
SFT2D2 SFT2 domain containing 2
SGK3 serum/glucocorticoid regulated kinase family, member 3
SH2B3 SH2B adaptor protein 3
SH2D1A SH2 domain containing 1A
SH2D3A SH2 domain containing 3A
SH3BP1 SH3-domain binding protein 1
SH3GL2 SH3-domain GRB2-like 2
SH3GLB1 SH3-domain GRB2-like endophilin B1
SH3GLB2 SH3-domain GRB2-like endophilin B2
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SHC3 SHC (Src homology 2 domain containing) transforming protein 3
SHD Src homology 2 domain containing transforming protein D
SIGMAR1 sigma non-opioid intracellular receptor 1
SKP1 S-phase kinase-associated protein 1
SLC30A9 solute carrier family 30 (zinc transporter), member 9
SMAD2 SMAD family member 2
SMAD4 SMAD family member 4
SMC1A structural maintenance of chromosomes 1A
SMC3 structural maintenance of chromosomes 3
SMC4 structural maintenance of chromosomes 4
SNAP23 synaptosomal-associated protein, 23kDa
SNAP29 synaptosomal-associated protein, 29kDa
SNAPIN SNAP-associated protein
SNF8 SNF8, ESCRT-II complex subunit
SNTB2 syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
SNX1 sorting nexin 1
SNX12 sorting nexin 12
SNX13 sorting nexin 13
SNX14 sorting nexin 14
SNX15 sorting nexin 15
SNX17 sorting nexin 17
SNX2 sorting nexin 2
SNX27 sorting nexin family member 27
SNX3 sorting nexin 3
SNX4 sorting nexin 4
SNX5 sorting nexin 5
SNX6 sorting nexin 6
SNX7 sorting nexin 7
SNX8 sorting nexin 8
SNX9 sorting nexin 9
SOS1 son of sevenless homolog 1 (Drosophila)
SPC25 SPC25, NDC80 kinetochore complex component
SPHK1 sphingosine kinase 1
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila)
SPRY2 sprouty homolog 2 (Drosophila)
SPRY3 sprouty homolog 3 (Drosophila)
SPRY4 sprouty homolog 4 (Drosophila)
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SSR1 signal sequence receptor, alpha
STAM signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
STARD7 StAR-related lipid transfer (START) domain containing 7
STAT1 signal transducer and activator of transcription 1, 91kDa
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor)
STAT5A signal transducer and activator of transcription 5A
STAT5B signal transducer and activator of transcription 5B
STAT6 signal transducer and activator of transcription 6, interleukin-4 induced
STEAP3 STEAP family member 3, metalloreductase
STK38 serine/threonine kinase 38
STK39 serine threonine kinase 39
STOML2 stomatin (EPB72)-like 2
STX12 syntaxin 12
STX17 syntaxin 17
STX18 syntaxin 18
STX3 syntaxin 3
STX4 syntaxin 4
STX5 syntaxin 5
STX7 syntaxin 7
STXBP2 syntaxin binding protein 2
STXBP3 syntaxin binding protein 3
SYK spleen tyrosine kinase
SYNJ2BP synaptojanin 2 binding protein
TAGLN2 transgelin 2
TAOK1 TAO kinase 1
TAOK3 TAO kinase 3
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
TBC1D1 TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
TBC1D10B TBC1 domain family, member 10B
TBC1D15 TBC1 domain family, member 15
TBC1D17 TBC1 domain family, member 17
TBC1D4 TBC1 domain family, member 4
TBC1D9B TBC1 domain family, member 9B (with GRAM domain)
TEC tec protein tyrosine kinase
TELO2 telomere maintenance 2
TGFA transforming growth factor, alpha
TGFBRAP1 transforming growth factor, beta receptor associated protein 1
TJP2 tight junction protein 2
TLN1 talin 1
TM9SF1 transmembrane 9 superfamily member 1
TMED1 transmembrane emp24 protein transport domain containing 1
TNFAIP8 tumor necrosis factor, alpha-induced protein 8
TNK1 tyrosine kinase, non-receptor, 1
TNS2 tensin 2
TNS3 tensin 3
TNS4 tensin 4
TRAPPC3 trafficking protein particle complex 3
TRAPPC4 trafficking protein particle complex 4
TRAPPC5 trafficking protein particle complex 5
TRIM24 tripartite motif containing 24
TRIM28 tripartite motif containing 28
TSC1 tuberous sclerosis 1
TSG101 tumor susceptibility 101
TTC19 tetratricopeptide repeat domain 19
TTI1 TELO2 interacting protein 1
TUBA4A tubulin, alpha 4a
TUBGCP2 tubulin, gamma complex associated protein 2
TUFM Tu translation elongation factor, mitochondrial
TXK TXK tyrosine kinase
TXLNA taxilin alpha
UBASH3B ubiquitin associated and SH3 domain containing B
UBC ubiquitin C
UNC93B1 unc-93 homolog B1 (C. elegans)
URGCP upregulator of cell proliferation
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae)
USO1 USO1 vesicle transport factor
USP9X ubiquitin specific peptidase 9, X-linked
VAC14 Vac14 homolog (S. cerevisiae)
VAMP3 vesicle-associated membrane protein 3
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C
VASP vasodilator-stimulated phosphoprotein
VAV1 vav 1 guanine nucleotide exchange factor
VAV2 vav 2 guanine nucleotide exchange factor
VAV3 vav 3 guanine nucleotide exchange factor
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae)
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae)
VPS18 vacuolar protein sorting 18 homolog (S. cerevisiae)
VPS25 vacuolar protein sorting 25 homolog (S. cerevisiae)
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae)
VPS29 vacuolar protein sorting 29 homolog (S. cerevisiae)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS33B vacuolar protein sorting 33 homolog B (yeast)
VPS35 vacuolar protein sorting 35 homolog (S. cerevisiae)
VPS36 vacuolar protein sorting 36 homolog (S. cerevisiae)
VPS37B vacuolar protein sorting 37 homolog B (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae)
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae)
VPS52 vacuolar protein sorting 52 homolog (S. cerevisiae)
VRK1 vaccinia related kinase 1
VTA1 vesicle (multivesicular body) trafficking 1
WASF1 WAS protein family, member 1
WASF2 WAS protein family, member 2
WASF3 WAS protein family, member 3
WASH2P WAS protein family homolog 2 pseudogene
WDFY1 WD repeat and FYVE domain containing 1
WDFY3 WD repeat and FYVE domain containing 3
WLS wntless Wnt ligand secretion mediator
XPO4 exportin 4
XPO7 exportin 7
XPOT exportin, tRNA
YES1 YES proto-oncogene 1, Src family tyrosine kinase
YIF1A Yip1 interacting factor homolog A (S. cerevisiae)
YKT6 YKT6 v-SNARE homolog (S. cerevisiae)
ZAP70 zeta-chain (TCR) associated protein kinase 70kDa
ZFPL1 zinc finger protein-like 1
ZMYM2 zinc finger, MYM-type 2
ZNF207 zinc finger protein 207
ZW10 zw10 kinetochore protein
ZWILCH zwilch kinetochore protein