ERCC4 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description excision repair cross-complementation group 4|The protein encoded by this gene forms a complex with ERCC1 and is involved in the 5' incision made during nucleotide excision repair. This complex is a structure specific DNA repair endonuclease that interacts with EME1. Defects in this gene are a cause of xeroderma pigmentosum complementation group F (XP-F), or xeroderma pigmentosum VI (XP6).[provided by RefSeq, Mar 2009] (NCBI Entrez Gene Database, 2072)
External Link http://www.ncbi.nlm.nih.gov/gene/2072
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Genes

209 interacting proteins for ERCC4 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AHCYL1 adenosylhomocysteinase-like 1
AHCYL2 adenosylhomocysteinase-like 2
ALB albumin
ALYREF Aly/REF export factor
ANXA1 annexin A1
ARHGEF4 Rho guanine nucleotide exchange factor (GEF) 4
ASPRV1 aspartic peptidase, retroviral-like 1
ATG3 autophagy related 3
ATG4B autophagy related 4B, cysteine peptidase
ATG7 autophagy related 7
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CALML3 calmodulin-like 3
CALML5 calmodulin-like 5
CAND1 cullin-associated and neddylation-dissociated 1
CDSN corneodesmosin
COPG1 coatomer protein complex, subunit gamma 1
COPS7A COP9 signalosome subunit 7A
CUL1 cullin 1
CUL2 cullin 2
CUL3 cullin 3
CUL4A cullin 4A
CUL4B cullin 4B
CUL5 cullin 5
DCAF10 DDB1 and CUL4 associated factor 10
DDA1 DET1 and DDB1 associated 1
DDB1 damage-specific DNA binding protein 1, 127kDa
DDX20 DEAD (Asp-Glu-Ala-Asp) box polypeptide 20
DNAJB6 DnaJ (Hsp40) homolog, subfamily B, member 6
DSC1 desmocollin 1
EEF1A1 eukaryotic translation elongation factor 1 alpha 1
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EEF2 eukaryotic translation elongation factor 2
EIF2A eukaryotic translation initiation factor 2A, 65kDa
EME1 essential meiotic structure-specific endonuclease 1
EMG1 EMG1 N1-specific pseudouridine methyltransferase
ERCC1 excision repair cross-complementation group 1
ERCC6 excision repair cross-complementation group 6
F7 coagulation factor VII (serum prothrombin conversion accelerator)
FABP5 fatty acid binding protein 5 (psoriasis-associated)
FANCA Fanconi anemia, complementation group A
FANCG Fanconi anemia, complementation group G
FBXW4 F-box and WD repeat domain containing 4
FKBP10 FK506 binding protein 10, 65 kDa
FLG filaggrin
GABARAP GABA(A) receptor-associated protein
GABARAPL1 GABA(A) receptor-associated protein like 1
GCN1L1 GCN1 general control of amino-acid synthesis 1-like 1 (yeast)
GEMIN4 gem (nuclear organelle) associated protein 4
GEMIN6 gem (nuclear organelle) associated protein 6
GID8 GID complex subunit 8
GLTSCR2 glioma tumor suppressor candidate region gene 2
GTF2H1 general transcription factor IIH, polypeptide 1, 62kDa
H2AFX H2A histone family, member X
HARS histidyl-tRNA synthetase
HIST2H2BE histone cluster 2, H2be
HP haptoglobin
HSPB1 heat shock 27kDa protein 1
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IGHA1 immunoglobulin heavy constant alpha 1
IGHM immunoglobulin heavy constant mu
IGKV1-5 immunoglobulin kappa variable 1-5
IGLC1 immunoglobulin lambda constant 1 (Mcg marker)
IPO7 importin 7
KARS lysyl-tRNA synthetase
KEAP1 kelch-like ECH-associated protein 1
KPNA1 karyopherin alpha 1 (importin alpha 5)
KPNA3 karyopherin alpha 3 (importin alpha 4)
KPNA4 karyopherin alpha 4 (importin alpha 3)
KRT3 keratin 3, type II
KRT4 keratin 4, type II
KRT84 keratin 84, type II
LRRC1 leucine rich repeat containing 1
MAGED1 melanoma antigen family D1
MCM4 minichromosome maintenance complex component 4
MCM5 minichromosome maintenance complex component 5
MKLN1 muskelin 1, intracellular mediator containing kelch motifs
MSH2 mutS homolog 2
MSH3 mutS homolog 3
MUS81 MUS81 structure-specific endonuclease subunit
MYH11 myosin, heavy chain 11, smooth muscle
MYO1C myosin IC
NAE1 NEDD8 activating enzyme E1 subunit 1
NCAPD3 non-SMC condensin II complex, subunit D3
NEDD8 neural precursor cell expressed, developmentally down-regulated 8
NUP153 nucleoporin 153kDa
NUP188 nucleoporin 188kDa
NUP50 nucleoporin 50kDa
PAGR1 PAXIP1 associated glutamate-rich protein 1
PCNA proliferating cell nuclear antigen
PGAM5 phosphoglycerate mutase family member 5
PIAS1 protein inhibitor of activated STAT, 1
PIAS2 protein inhibitor of activated STAT, 2
PLK1 polo-like kinase 1
PNMA2 paraneoplastic Ma antigen 2
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
POLR2G polymerase (RNA) II (DNA directed) polypeptide G
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
PRKCI protein kinase C, iota
PRPF3 pre-mRNA processing factor 3
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1
PSMA2 proteasome (prosome, macropain) subunit, alpha type, 2
PSMA3 proteasome (prosome, macropain) subunit, alpha type, 3
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7
PSMB1 proteasome (prosome, macropain) subunit, beta type, 1
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3
PSMB4 proteasome (prosome, macropain) subunit, beta type, 4
PSMB5 proteasome (prosome, macropain) subunit, beta type, 5
PSMD11 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
PSME3 proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki)
RAD52 RAD52 homolog (S. cerevisiae)
RAN RAN, member RAS oncogene family
RANBP9 RAN binding protein 9
RANGAP1 Ran GTPase activating protein 1
RNASEH1 ribonuclease H1
RNF20 ring finger protein 20, E3 ubiquitin protein ligase
RPL10A ribosomal protein L10a
RPL11 ribosomal protein L11
RPL12 ribosomal protein L12
RPL13 ribosomal protein L13
RPL18 ribosomal protein L18
RPL21 ribosomal protein L21
RPL23 ribosomal protein L23
RPL24 ribosomal protein L24
RPL26 ribosomal protein L26
RPL27 ribosomal protein L27
RPL29 ribosomal protein L29
RPL30 ribosomal protein L30
RPL31 ribosomal protein L31
RPL35A ribosomal protein L35a
RPL5 ribosomal protein L5
RPL6 ribosomal protein L6
RPL7 ribosomal protein L7
RPL7A ribosomal protein L7a
RPL8 ribosomal protein L8
RPN1 ribophorin I
RPS11 ribosomal protein S11
RPS13 ribosomal protein S13
RPS14 ribosomal protein S14
RPS15A ribosomal protein S15a
RPS16 ribosomal protein S16
RPS2 ribosomal protein S2
RPS20 ribosomal protein S20
RPS23 ribosomal protein S23
RPS26 ribosomal protein S26
RPS3 ribosomal protein S3
RPS4X ribosomal protein S4, X-linked
RPS6 ribosomal protein S6
RPS7 ribosomal protein S7
RPS8 ribosomal protein S8
S100A8 S100 calcium binding protein A8
SCN1A sodium channel, voltage gated, type I alpha subunit
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SERPINB4 serpin peptidase inhibitor, clade B (ovalbumin), member 4
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5
SF3B3 splicing factor 3b, subunit 3, 130kDa
SLC25A13 solute carrier family 25 (aspartate/glutamate carrier), member 13
SLIRP SRA stem-loop interacting RNA binding protein
SLX1B SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae)
SLX4 SLX4 structure-specific endonuclease subunit
SLX4IP SLX4 interacting protein
SMN2 survival of motor neuron 2, centromeric
SPTA1 spectrin, alpha, erythrocytic 1
SPTAN1 spectrin, alpha, non-erythrocytic 1
SQSTM1 sequestosome 1
SSRP1 structure specific recognition protein 1
STK4 serine/threonine kinase 4
STRAP serine/threonine kinase receptor associated protein
SUMO2 small ubiquitin-like modifier 2
SUMO3 small ubiquitin-like modifier 3
SYNE2 spectrin repeat containing, nuclear envelope 2
TADA2A transcriptional adaptor 2A
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TARS threonyl-tRNA synthetase
TERF2 telomeric repeat binding factor 2
TERF2IP telomeric repeat binding factor 2, interacting protein
TEX10 testis expressed 10
TF transferrin
TGM3 transglutaminase 3
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast)
TSPYL1 TSPY-like 1
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBC ubiquitin C
UBE2B ubiquitin-conjugating enzyme E2B
UBE2M ubiquitin-conjugating enzyme E2M
UBE2O ubiquitin-conjugating enzyme E2O
UBR5 ubiquitin protein ligase E3 component n-recognin 5
UQCRC2 ubiquinol-cytochrome c reductase core protein II
VPRBP Vpr (HIV-1) binding protein
VPS26A vacuolar protein sorting 26 homolog A (S. pombe)
XPC xeroderma pigmentosum, complementation group C
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
YWHAH tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
ZYX zyxin