ERG Gene Set

Dataset LINCS L1000 CMAP CRISPR Knockout Consensus Signatures
Category transcriptomics
Type gene perturbation
Description v-ets avian erythroblastosis virus E26 oncogene homolog|This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. More than two dozens of transcript variants generated from combinatorial usage of three alternative promoters and multiple alternative splicing events have been reported, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Apr 2014] (NCBI Entrez Gene Database, 2078)
External Link https://ncbi.nlm.nih.gov/gene/2078
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Genes

498 genes differentially expressed following the ERG gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

increased expression

Symbol Name Standardized Value
CXCL12 chemokine (C-X-C motif) ligand 12 0.0185149
FABP7 fatty acid binding protein 7, brain 0.0180057
RGS4 regulator of G-protein signaling 4 0.0154764
TLR4 toll-like receptor 4 0.0135423
BEX1 brain expressed, X-linked 1 0.0123347
SNCA synuclein, alpha (non A4 component of amyloid precursor) 0.012289
POSTN periostin, osteoblast specific factor 0.0119419
MEN1 multiple endocrine neoplasia I 0.0117124
CLTB clathrin, light chain B 0.0117005
PADI2 peptidyl arginine deiminase, type II 0.0116918
EIF5A eukaryotic translation initiation factor 5A 0.0111362
SNAP25 synaptosomal-associated protein, 25kDa 0.0110326
CA2 carbonic anhydrase II 0.0108525
WDR7 WD repeat domain 7 0.0105744
FAIM Fas apoptotic inhibitory molecule 0.0104895
DIRAS3 DIRAS family, GTP-binding RAS-like 3 0.0104782
PITX3 paired-like homeodomain 3 0.0101129
STMN2 stathmin 2 0.0100382
PEG3 paternally expressed 3 0.00999723
FOXG1 forkhead box G1 0.00988502
AK5 adenylate kinase 5 0.00966374
DHRS2 dehydrogenase/reductase (SDR family) member 2 0.00941482
TNIP1 TNFAIP3 interacting protein 1 0.0093713
UGT2B28 UDP glucuronosyltransferase 2 family, polypeptide B28 0.0093429
ZIC1 Zic family member 1 0.0093177
MAL mal, T-cell differentiation protein 0.00920245
MVP major vault protein 0.00913521
NEFM neurofilament, medium polypeptide 0.00883093
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 0.00878003
LTF lactotransferrin 0.0087583
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4 0.00868613
IFRD2 interferon-related developmental regulator 2 0.00859674
S100A7 S100 calcium binding protein A7 0.00846512
DNAJA3 DnaJ (Hsp40) homolog, subfamily A, member 3 0.00837577
COG7 component of oligomeric golgi complex 7 0.00836251
TFF1 trefoil factor 1 0.00831864
EIF4EBP1 eukaryotic translation initiation factor 4E binding protein 1 0.00815871
EMX2 empty spiracles homeobox 2 0.0081494
APOBEC3B apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B 0.0081411
TMED9 transmembrane emp24 protein transport domain containing 9 0.00799325
IL17RB interleukin 17 receptor B 0.00795286
TP53 tumor protein p53 0.00792554
CNR1 cannabinoid receptor 1 (brain) 0.00789027
ERAP2 endoplasmic reticulum aminopeptidase 2 0.00784837
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa 0.00781759
SORBS3 sorbin and SH3 domain containing 3 0.00779298
MBOAT7 membrane bound O-acyltransferase domain containing 7 0.00768459
ADGRE5 adhesion G protein-coupled receptor E5 0.00763282
NRN1 neuritin 1 0.00761996
SYT1 synaptotagmin I 0.00761285
ALDOA aldolase A, fructose-bisphosphate 0.00757942
COL11A1 collagen, type XI, alpha 1 0.0075774
PAFAH1B3 platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa) 0.00755688
ILK integrin-linked kinase 0.00753963
L1CAM L1 cell adhesion molecule 0.0075009
SSR3 signal sequence receptor, gamma (translocon-associated protein gamma) 0.00749339
CASP2 caspase 2, apoptosis-related cysteine peptidase 0.00746344
GUCY2C guanylate cyclase 2C 0.00742338
ASCL1 achaete-scute family bHLH transcription factor 1 0.00741992
PMP2 peripheral myelin protein 2 0.00741687
AKAP12 A kinase (PRKA) anchor protein 12 0.00741506
RFC2 replication factor C (activator 1) 2, 40kDa 0.00741383
ETFB electron-transfer-flavoprotein, beta polypeptide 0.00741123
DMD dystrophin 0.00738294
MYBPC1 myosin binding protein C, slow type 0.00736277
LPPR4 lipid phosphate phosphatase-related protein type 4 0.00735239
SLC2A5 solute carrier family 2 (facilitated glucose/fructose transporter), member 5 0.00733672
CLDN8 claudin 8 0.00730022
CEMIP cell migration inducing protein, hyaluronan binding 0.007282
GAP43 growth associated protein 43 0.00722475
NTRK2 neurotrophic tyrosine kinase, receptor, type 2 0.00716697
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.00712173
ADD3 adducin 3 (gamma) 0.00709193
PRKACA protein kinase, cAMP-dependent, catalytic, alpha 0.00708854
ARID4A AT rich interactive domain 4A (RBP1-like) 0.00707093
MT1H metallothionein 1H 0.00706064
DLK1 delta-like 1 homolog (Drosophila) 0.0070312
SV2A synaptic vesicle glycoprotein 2A 0.0070237
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) 0.00701854
VSNL1 visinin-like 1 0.00697696
TAGLN3 transgelin 3 0.00694824
GPI glucose-6-phosphate isomerase 0.0069392
TMEM158 transmembrane protein 158 (gene/pseudogene) 0.00690515
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta 0.00690238
ADGRE1 adhesion G protein-coupled receptor E1 0.00689952
PRMT1 protein arginine methyltransferase 1 0.00688738
CDK14 cyclin-dependent kinase 14 0.00687237
NDRG4 NDRG family member 4 0.00687029
AHNAK AHNAK nucleoprotein 0.00685547
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase) 0.00684981
ANXA6 annexin A6 0.00684445
CREB3L1 cAMP responsive element binding protein 3-like 1 0.00682889
ZNF365 zinc finger protein 365 0.00682888
PLP1 proteolipid protein 1 0.00681254
CRABP1 cellular retinoic acid binding protein 1 0.0067421
CEACAM1 carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) 0.00668219
LRRC17 leucine rich repeat containing 17 0.00667049
THBS2 thrombospondin 2 0.00665799
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain 0.00664412
TNC tenascin C 0.00659593
ZYX zyxin 0.0065784
DOK5 docking protein 5 0.00654185
TARBP1 TAR (HIV-1) RNA binding protein 1 0.0065375
SIRT3 sirtuin 3 0.00652377
CDH2 cadherin 2, type 1, N-cadherin (neuronal) 0.00651098
MT3 metallothionein 3 0.0064939
ACTN1 actinin, alpha 1 0.00646641
ATP6V1H ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H 0.0064601
MAB21L2 mab-21-like 2 (C. elegans) 0.00645423
CDH1 cadherin 1, type 1, E-cadherin (epithelial) 0.00644757
BAX BCL2-associated X protein 0.00642792
ADAM19 ADAM metallopeptidase domain 19 0.00642382
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.00638745
OXTR oxytocin receptor 0.00637941
MYBL2 v-myb avian myeloblastosis viral oncogene homolog-like 2 0.00637623
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa 0.0063565
SLC7A1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 0.00634985
PLAUR plasminogen activator, urokinase receptor 0.00628158
MT1HL1 metallothionein 1H-like 1 0.00628143
SPRR3 small proline-rich protein 3 0.00627375
UCHL1 ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) 0.0062567
WDR1 WD repeat domain 1 0.00625254
PNMA2 paraneoplastic Ma antigen 2 0.00624772
NRCAM neuronal cell adhesion molecule 0.00623878
ZNF91 zinc finger protein 91 0.00623863
PPBP pro-platelet basic protein (chemokine (C-X-C motif) ligand 7) 0.00619903
SPRED2 sprouty-related, EVH1 domain containing 2 0.00617154
PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 0.00617083
B2M beta-2-microglobulin 0.00614492
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.00610057
COL6A3 collagen, type VI, alpha 3 0.00608941
BMP7 bone morphogenetic protein 7 0.00608142
SCGB2A1 secretoglobin, family 2A, member 1 0.00606903
ARPP19 cAMP-regulated phosphoprotein, 19kDa 0.00605593
NT5DC2 5'-nucleotidase domain containing 2 0.00603907
USP13 ubiquitin specific peptidase 13 (isopeptidase T-3) 0.0060351
LOX lysyl oxidase 0.0060318
UMOD uromodulin 0.00602594
WASHC4 WASH complex subunit 4 0.00602257
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast) 0.00600723
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.00597913
MBD2 methyl-CpG binding domain protein 2 0.0059582
SV2B synaptic vesicle glycoprotein 2B 0.00595765
SFRP1 secreted frizzled-related protein 1 0.00595551
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.00595406
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 0.00595405
GLIPR1 GLI pathogenesis-related 1 0.00594476
DBN1 drebrin 1 0.00593306
HMGB2 high mobility group box 2 0.00591438
MARCKS myristoylated alanine-rich protein kinase C substrate 0.0059047
MEIS2 Meis homeobox 2 0.00589682
GPC3 glypican 3 0.00589678
COX4I1 cytochrome c oxidase subunit IV isoform 1 0.00588803
MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle 0.00587603
AFG3L2 AFG3-like AAA ATPase 2 0.00584586
CFDP1 craniofacial development protein 1 0.0058297
PIH1D1 PIH1 domain containing 1 0.00581163
MEG3 maternally expressed 3 (non-protein coding) 0.00581062
ANXA2P2 annexin A2 pseudogene 2 0.00580049
BAMBI BMP and activin membrane-bound inhibitor 0.00579061
NAGPA N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase 0.0057676
MMP12 matrix metallopeptidase 12 0.00576625
TYRP1 tyrosinase-related protein 1 0.00576156
IFITM3 interferon induced transmembrane protein 3 0.00572446
TCEAL2 transcription elongation factor A (SII)-like 2 0.0057078
EDN3 endothelin 3 0.00568466
APOA1 apolipoprotein A-I 0.00568098
DAXX death-domain associated protein 0.0056726
CAPNS1 calpain, small subunit 1 0.00565747
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 0.00565443
SCD5 stearoyl-CoA desaturase 5 0.00564178
GYS1 glycogen synthase 1 (muscle) 0.0056398
STX10 syntaxin 10 0.00563926
HMBS hydroxymethylbilane synthase 0.00563773
IGFBP5 insulin-like growth factor binding protein 5 0.00563093
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta 0.00562222
RNF128 ring finger protein 128, E3 ubiquitin protein ligase 0.00561874
FLNA filamin A, alpha 0.00561591
PITX1 paired-like homeodomain 1 0.00560229
HLA-B major histocompatibility complex, class I, B 0.0055998
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.00559814
GRIA2 glutamate receptor, ionotropic, AMPA 2 0.00559161
PARN poly(A)-specific ribonuclease 0.00558593
PRKAR2A protein kinase, cAMP-dependent, regulatory, type II, alpha 0.00557109
ZFHX4 zinc finger homeobox 4 0.00556932
MT2A metallothionein 2A 0.00554794
SMAGP small cell adhesion glycoprotein 0.00553881
ZDHHC7 zinc finger, DHHC-type containing 7 0.0055352
SCN3B sodium channel, voltage gated, type III beta subunit 0.00553511
FKBP10 FK506 binding protein 10, 65 kDa 0.00551645
RIPOR2 RHO family interacting cell polarization regulator 2 0.00551319
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7 0.0055047
AP1S2 adaptor-related protein complex 1, sigma 2 subunit 0.00550175
TRAF3IP2 TRAF3 interacting protein 2 0.00549328
H1-10 H1.10 linker histone 0.00548586
PI3 peptidase inhibitor 3, skin-derived 0.00548503
THBS1 thrombospondin 1 0.00548383
SOX10 SRY (sex determining region Y)-box 10 0.00547833
APLP1 amyloid beta (A4) precursor-like protein 1 0.00546681
KLHDC8A kelch domain containing 8A 0.00546151
DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 0.00545678
ASH2L ash2 (absent, small, or homeotic)-like (Drosophila) 0.00545068
DNAJC6 DnaJ (Hsp40) homolog, subfamily C, member 6 0.00544721
ATP6V1A ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A 0.00544463
HLA-DOB major histocompatibility complex, class II, DO beta 0.00542121
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) 0.00541739
MED22 mediator complex subunit 22 0.00540562
ASXL2 additional sex combs like transcriptional regulator 2 0.00539773
CDH16 cadherin 16, KSP-cadherin 0.00539132
ELAVL4 ELAV like neuron-specific RNA binding protein 4 0.005389
NOL3 nucleolar protein 3 (apoptosis repressor with CARD domain) 0.00538376
LDB2 LIM domain binding 2 0.00538337
FHL3 four and a half LIM domains 3 0.00536499
ARL6IP1 ADP-ribosylation factor-like 6 interacting protein 1 0.00535515
FAM171A1 family with sequence similarity 171, member A1 0.00534098
AMPD2 adenosine monophosphate deaminase 2 0.00533989
BIRC5 baculoviral IAP repeat containing 5 0.00533821
ATP1B2 ATPase, Na+/K+ transporting, beta 2 polypeptide 0.00531433
CDC20 cell division cycle 20 0.00531144
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1 0.00531063
SIGLEC15 sialic acid binding Ig-like lectin 15 0.00529977
BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) 0.00529687
SLC9A3R1 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 0.00529365
HSPB1 heat shock 27kDa protein 1 0.00528345
COL6A1 collagen, type VI, alpha 1 0.00528146
RAB6B RAB6B, member RAS oncogene family 0.00528102
HMGA1 high mobility group AT-hook 1 0.00527484
LRRC8D leucine rich repeat containing 8 family, member D 0.00526594
AKAP8 A kinase (PRKA) anchor protein 8 0.00526219
ADM adrenomedullin 0.00526192
ADAT1 adenosine deaminase, tRNA-specific 1 0.00525636
HSD11B2 hydroxysteroid (11-beta) dehydrogenase 2 0.00523588
NPIPB3 nuclear pore complex interacting protein family, member B3 0.00523503
PDZK1 PDZ domain containing 1 0.00522238
SALL1 spalt-like transcription factor 1 0.00520669
RSL1D1 ribosomal L1 domain containing 1 0.00520489
PRKCA protein kinase C, alpha 0.00519688
BFAR bifunctional apoptosis regulator 0.00519605
F12 coagulation factor XII (Hageman factor) 0.00519493
PAK3 p21 protein (Cdc42/Rac)-activated kinase 3 0.0051918
AIM2 absent in melanoma 2 0.00518778
SELL selectin L 0.00517993
HTRA1 HtrA serine peptidase 1 0.00516943
FLOT2 flotillin 2 0.00516784
CLDN10 claudin 10 0.00516106
FAIM2 Fas apoptotic inhibitory molecule 2 0.0051576
TWF2 twinfilin actin binding protein 2 0.00515176
CNN2 calponin 2 0.00514487
HIGD2A HIG1 hypoxia inducible domain family, member 2A 0.00514315
COL1A2 collagen, type I, alpha 2 0.00513319

decreased expression

Symbol Name Standardized Value
SSBP2 single-stranded DNA binding protein 2 -0.0221066
AMIGO2 adhesion molecule with Ig-like domain 2 -0.0148556
LSM5 LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) -0.0146806
MAT2A methionine adenosyltransferase II, alpha -0.0138818
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) -0.013825
HOPX HOP homeobox -0.0134682
STXBP2 syntaxin binding protein 2 -0.0125053
CXCL11 chemokine (C-X-C motif) ligand 11 -0.0121478
APOD apolipoprotein D -0.0119296
AGR2 anterior gradient 2 -0.0119016
CYP4B1 cytochrome P450, family 4, subfamily B, polypeptide 1 -0.0116678
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -0.0116215
IFI27 interferon, alpha-inducible protein 27 -0.0113863
MAP7 microtubule-associated protein 7 -0.0109891
MX1 MX dynamin-like GTPase 1 -0.0109124
C1QB complement component 1, q subcomponent, B chain -0.0109111
TPSAB1 tryptase alpha/beta 1 -0.0108311
OSR2 odd-skipped related transciption factor 2 -0.0106842
SPON2 spondin 2, extracellular matrix protein -0.0106167
PMP22 peripheral myelin protein 22 -0.0105731
ADIRF adipogenesis regulatory factor -0.010462
PLAAT3 phospholipase A and acyltransferase 3 -0.0101914
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 -0.00994097
ADGRF5 adhesion G protein-coupled receptor F5 -0.00980718
JCHAIN joining chain of multimeric IgA and IgM -0.00976533
G0S2 G0/G1 switch 2 -0.00976311
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) -0.00975092
IFI44L interferon-induced protein 44-like -0.00973675
WASL Wiskott-Aldrich syndrome-like -0.00969617
TSPAN13 tetraspanin 13 -0.00956489
CLEC3B C-type lectin domain family 3, member B -0.00952518
CLEC2B C-type lectin domain family 2, member B -0.00947389
AQP1 aquaporin 1 (Colton blood group) -0.00946895
RRAGA Ras-related GTP binding A -0.00941325
IFI6 interferon, alpha-inducible protein 6 -0.00933404
CD69 CD69 molecule -0.00931655
TOX3 TOX high mobility group box family member 3 -0.00931124
COL4A5 collagen, type IV, alpha 5 -0.00928088
S100P S100 calcium binding protein P -0.00925886
AMH anti-Mullerian hormone -0.00922168
CHRDL1 chordin-like 1 -0.0091257
COL15A1 collagen, type XV, alpha 1 -0.00910643
ARHGAP29 Rho GTPase activating protein 29 -0.00908497
RIN2 Ras and Rab interactor 2 -0.00906293
RSAD2 radical S-adenosyl methionine domain containing 2 -0.00900997
ITM2A integral membrane protein 2A -0.00900115
IRF7 interferon regulatory factor 7 -0.00892589
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha -0.00890618
IFIT1 interferon-induced protein with tetratricopeptide repeats 1 -0.00884362
DEGS1 delta(4)-desaturase, sphingolipid 1 -0.00882903
CTSH cathepsin H -0.0088225
CXCL10 chemokine (C-X-C motif) ligand 10 -0.00880356
GZMA granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) -0.00863843
CCL20 chemokine (C-C motif) ligand 20 -0.00859625
CCL8 chemokine (C-C motif) ligand 8 -0.00855824
ISG15 ISG15 ubiquitin-like modifier -0.00854379
C1QA complement component 1, q subcomponent, A chain -0.00853464
KANK2 KN motif and ankyrin repeat domains 2 -0.0085231
NKX3-1 NK3 homeobox 1 -0.00850249
PLTP phospholipid transfer protein -0.00845345
AKR1C1 aldo-keto reductase family 1, member C1 -0.00827787
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) -0.00827167
SMAD7 SMAD family member 7 -0.00826933
NDNF neuron-derived neurotrophic factor -0.00826871
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide -0.00824617
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) -0.00820443
GPX3 glutathione peroxidase 3 -0.00819572
TACSTD2 tumor-associated calcium signal transducer 2 -0.00819352
INTS6 integrator complex subunit 6 -0.00817464
NAT1 N-acetyltransferase 1 (arylamine N-acetyltransferase) -0.00816419
COL4A6 collagen, type IV, alpha 6 -0.00800485
SELENBP1 selenium binding protein 1 -0.00800104
FRZB frizzled-related protein -0.00798003
SLC30A1 solute carrier family 30 (zinc transporter), member 1 -0.00795934
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class) -0.00791537
SGMS1 sphingomyelin synthase 1 -0.00789399
LTBP2 latent transforming growth factor beta binding protein 2 -0.00787378
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3 -0.00787175
SCUBE2 signal peptide, CUB domain, EGF-like 2 -0.00786638
CFB complement factor B -0.00784645
FOXF1 forkhead box F1 -0.00784035
CAV1 caveolin 1, caveolae protein, 22kDa -0.00783164
SIK1 salt-inducible kinase 1 -0.00781261
RNF19B ring finger protein 19B -0.0078012
SFN stratifin -0.00772963
VWF von Willebrand factor -0.00771755
PELO pelota homolog (Drosophila) -0.00769154
MFAP4 microfibrillar-associated protein 4 -0.0076768
RARRES3 retinoic acid receptor responder (tazarotene induced) 3 -0.00767572
CASP10 caspase 10, apoptosis-related cysteine peptidase -0.00766331
FBXO11 F-box protein 11 -0.00763114
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa -0.00760072
RBL2 retinoblastoma-like 2 -0.00758282
BMI1 BMI1 proto-oncogene, polycomb ring finger -0.00757192
AKR1C2 aldo-keto reductase family 1, member C2 -0.00755558
TYROBP TYRO protein tyrosine kinase binding protein -0.00754896
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 -0.00753715
STK26 serine/threonine protein kinase 26 -0.0075282
GALC galactosylceramidase -0.00747784
SPRY1 sprouty homolog 1, antagonist of FGF signaling (Drosophila) -0.00746459
MFHAS1 malignant fibrous histiocytoma amplified sequence 1 -0.00746198
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) -0.0074618
ADO 2-aminoethanethiol (cysteamine) dioxygenase -0.00737045
EZR ezrin -0.00725571
CTSK cathepsin K -0.00724939
CXCL13 chemokine (C-X-C motif) ligand 13 -0.00722274
RASL12 RAS-like, family 12 -0.00722158
EPHX1 epoxide hydrolase 1, microsomal (xenobiotic) -0.00719663
CCL19 chemokine (C-C motif) ligand 19 -0.00719322
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3 -0.00718712
TPST2 tyrosylprotein sulfotransferase 2 -0.00717732
GATA6 GATA binding protein 6 -0.00714436
VAMP8 vesicle-associated membrane protein 8 -0.0071441
CCN2 cellular communication network factor 2 -0.0071228
GNLY granulysin -0.00711312
FASTKD3 FAST kinase domains 3 -0.00710546
TXNDC9 thioredoxin domain containing 9 -0.00710168
COMP cartilage oligomeric matrix protein -0.00710092
CXCL9 chemokine (C-X-C motif) ligand 9 -0.0070791
SC5D sterol-C5-desaturase -0.00707507
PLA1A phospholipase A1 member A -0.00705352
LPCAT1 lysophosphatidylcholine acyltransferase 1 -0.00703033
MAOA monoamine oxidase A -0.00701942
TNFAIP8 tumor necrosis factor, alpha-induced protein 8 -0.00701738
SIKE1 suppressor of IKBKE 1 -0.00701736
TMEM106B transmembrane protein 106B -0.00701077
TPD52 tumor protein D52 -0.00700509
CRY1 cryptochrome circadian clock 1 -0.00700253
AKR1C3 aldo-keto reductase family 1, member C3 -0.00698586
TOB1 transducer of ERBB2, 1 -0.00692543
TKTL1 transketolase-like 1 -0.00687506
ACKR3 atypical chemokine receptor 3 -0.00686588
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.00686244
RBPMS RNA binding protein with multiple splicing -0.00685068
SFTPB surfactant protein B -0.00679771
DYNLT1 dynein, light chain, Tctex-type 1 -0.00679696
IL13RA2 interleukin 13 receptor, alpha 2 -0.0067854
HSD11B1 hydroxysteroid (11-beta) dehydrogenase 1 -0.00677337
NDUFA4 NDUFA4, mitochondrial complex associated -0.00675412
FZD5 frizzled class receptor 5 -0.00674324
IGF1 insulin-like growth factor 1 (somatomedin C) -0.00672552
GPX2 glutathione peroxidase 2 -0.00672242
LUM lumican -0.0067216
MYO5C myosin VC -0.0066969
CNIH4 cornichon family AMPA receptor auxiliary protein 4 -0.00668632
SMYD3 SET and MYND domain containing 3 -0.00666877
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 -0.00666691
UPP1 uridine phosphorylase 1 -0.00666234
SLC38A1 solute carrier family 38, member 1 -0.0066555
PTGIS prostaglandin I2 (prostacyclin) synthase -0.00665407
IRF9 interferon regulatory factor 9 -0.00664843
SLC39A8 solute carrier family 39 (zinc transporter), member 8 -0.00664546
C8ORF4 chromosome 8 open reading frame 4 -0.00663976
CCL13 chemokine (C-C motif) ligand 13 -0.00663664
KLK11 kallikrein-related peptidase 11 -0.00661705
CFH complement factor H -0.00661388
ODC1 ornithine decarboxylase 1 -0.00660034
PTPN13 protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) -0.00658353
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase -0.00658272
PROCR protein C receptor, endothelial -0.00657057
ACKR1 atypical chemokine receptor 1 (Duffy blood group) -0.00655542
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 -0.00653821
WWC3 WWC family member 3 -0.00653462
SLCO4A1 solute carrier organic anion transporter family, member 4A1 -0.00652496
RSF1 remodeling and spacing factor 1 -0.00650998
RAD51AP1 RAD51 associated protein 1 -0.00650602
MS4A6A membrane-spanning 4-domains, subfamily A, member 6A -0.00644335
ZBTB18 zinc finger and BTB domain containing 18 -0.00642872
PIK3C2B phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta -0.00641891
AOC3 amine oxidase, copper containing 3 -0.00639281
DKFZP586I1420 uncharacterized protein DKFZp586I1420 -0.00633949
ADCY9 adenylate cyclase 9 -0.00633309
SYNM synemin, intermediate filament protein -0.00633022
MYO1D myosin ID -0.00631054
DESI1 desumoylating isopeptidase 1 -0.00627089
GPRC5A G protein-coupled receptor, class C, group 5, member A -0.0062692
DCN decorin -0.0062619
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) -0.00625669
CD163 CD163 molecule -0.00625596
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3 -0.00623859
NBPF10 neuroblastoma breakpoint family, member 10 -0.00621602
TBX3 T-box 3 -0.00620882
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -0.0062063
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta -0.00620438
RHOB ras homolog family member B -0.00620357
ADGRG6 adhesion G protein-coupled receptor G6 -0.00619482
PBX1 pre-B-cell leukemia homeobox 1 -0.00619235
C4BPA complement component 4 binding protein, alpha -0.00617424
HAUS3 HAUS augmin-like complex, subunit 3 -0.00614848
ATP11B ATPase, class VI, type 11B -0.00609626
ANOS1 anosmin 1 -0.00607773
STAB1 stabilin 1 -0.00607354
RIT1 Ras-like without CAAX 1 -0.00606254
KMT5B lysine methyltransferase 5B -0.00604443
RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 -0.00603984
ARL4A ADP-ribosylation factor-like 4A -0.00603387
LGALS8 lectin, galactoside-binding, soluble, 8 -0.00603047
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast) -0.00602833
FBLN2 fibulin 2 -0.00601592
YBX3 Y box binding protein 3 -0.005995
GEM GTP binding protein overexpressed in skeletal muscle -0.00599357
EFNB2 ephrin-B2 -0.00599343
RYBP RING1 and YY1 binding protein -0.0059929
PRKAR1A protein kinase, cAMP-dependent, regulatory, type I, alpha -0.00589766
CCND1 cyclin D1 -0.00589117
CLU clusterin -0.00588759
ARID4B AT rich interactive domain 4B (RBP1-like) -0.00588257
HMGB3 high mobility group box 3 -0.00587589
PAEP progestagen-associated endometrial protein -0.00586027
DPT dermatopontin -0.00583881
NKG7 natural killer cell granule protein 7 -0.00582404
MXRA7 matrix-remodelling associated 7 -0.00582292
DOCK9 dedicator of cytokinesis 9 -0.00582232
MIOS missing oocyte, meiosis regulator, homolog (Drosophila) -0.00581357
RGCC regulator of cell cycle -0.0058011
COL14A1 collagen, type XIV, alpha 1 -0.00578665
SPTAN1 spectrin, alpha, non-erythrocytic 1 -0.00577994
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase -0.00576443
PTGER4 prostaglandin E receptor 4 (subtype EP4) -0.00576393
DLG5 discs, large homolog 5 (Drosophila) -0.00575987
TUBB2A tubulin, beta 2A class IIa -0.0057595
CLGN calmegin -0.00575609
OGT O-linked N-acetylglucosamine (GlcNAc) transferase -0.00573667
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 -0.00572013
PPAP2A phosphatidic acid phosphatase type 2A -0.00570617
PFDN4 prefoldin subunit 4 -0.00570322
GCLC glutamate-cysteine ligase, catalytic subunit -0.00569749
PCNA proliferating cell nuclear antigen -0.00568318
EXPH5 exophilin 5 -0.00568268
TFAM transcription factor A, mitochondrial -0.00567327
AREG amphiregulin -0.00567307
THAP12 THAP domain containing 12 -0.00566707
JMJD1C jumonji domain containing 1C -0.005659
VWA1 von Willebrand factor A domain containing 1 -0.00565287
SERPINB9 serpin peptidase inhibitor, clade B (ovalbumin), member 9 -0.00564887
ADGRG2 adhesion G protein-coupled receptor G2 -0.00564585
MED21 mediator complex subunit 21 -0.00563518
JARID2 jumonji, AT rich interactive domain 2 -0.00562792
PRF1 perforin 1 (pore forming protein) -0.00562376
DUSP5 dual specificity phosphatase 5 -0.00561459
LUC7L3 LUC7-like 3 (S. cerevisiae) -0.00561256
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) -0.00559741
NXN nucleoredoxin -0.00559734
IL1R1 interleukin 1 receptor, type I -0.00558166
N4BP1 NEDD4 binding protein 1 -0.00557013
PRPF3 pre-mRNA processing factor 3 -0.00555437
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) -0.0055479
TCF12 transcription factor 12 -0.00554043