| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ERK5-IN-2 perturbation in SW48 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ERK5-IN-2_SW48 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.10305 |
| EGFR | epidermal growth factor receptor | 0.0834311 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0522407 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0516151 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0481804 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0475776 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0399026 |
| ANXA2 | annexin A2 | 0.0397093 |
| RCOR1 | REST corepressor 1 | 0.0367132 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0361688 |
| SEPTIN9 | septin 9 | 0.0331612 |
| FAT1 | FAT atypical cadherin 1 | 0.0329661 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0310272 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0286358 |
| LAMC2 | laminin, gamma 2 | 0.0274167 |
| SGMS2 | sphingomyelin synthase 2 | 0.0272507 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0257729 |
| DSPP | dentin sialophosphoprotein | 0.0256252 |
| LAMA4 | laminin, alpha 4 | 0.0254639 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0253554 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0249132 |
| EGR1 | early growth response 1 | 0.0248216 |
| MYO5B | myosin VB | 0.0248011 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0239004 |
| CTSB | cathepsin B | 0.0238672 |
| SMAD3 | SMAD family member 3 | 0.023233 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0227384 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0224154 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0220042 |
| SGPP2 | sphingosine-1-phosphate phosphatase 2 | 0.021935 |
| RPL13A | ribosomal protein L13a | 0.0215056 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0213644 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0211424 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0208943 |
| FLNA | filamin A, alpha | 0.0207507 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0204664 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0200705 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0199211 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0196175 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0196156 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0193303 |
| GPC5 | glypican 5 | 0.0190969 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0189143 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0188917 |
| ABR | active BCR-related | 0.018767 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0182058 |
| RPS12 | ribosomal protein S12 | 0.0181519 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0179513 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0179086 |
| GOLGB1 | golgin B1 | 0.0178506 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0176637 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0176365 |
| RPL21 | ribosomal protein L21 | 0.0175856 |
| LDHA | lactate dehydrogenase A | 0.0170935 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0167278 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0165934 |
| RPS18 | ribosomal protein S18 | 0.0164852 |
| CMIP | c-Maf inducing protein | 0.0164003 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0163565 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.016278 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0161715 |
| PUM1 | pumilio RNA-binding family member 1 | 0.0161176 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | 0.0158129 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0156523 |
| VEGFA | vascular endothelial growth factor A | 0.0156098 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0154996 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0152749 |
| RPL29 | ribosomal protein L29 | 0.0152566 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0151506 |
| GPHN | gephyrin | 0.0151039 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0150862 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0150804 |
| RPL3 | ribosomal protein L3 | 0.0149989 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0149926 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0149534 |
| HOMER1 | homer scaffolding protein 1 | 0.0148412 |
| EPHA2 | EPH receptor A2 | 0.0146462 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0144955 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0144304 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | 0.0143318 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0142063 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0141955 |
| HDLBP | high density lipoprotein binding protein | 0.0140669 |
| FHL2 | four and a half LIM domains 2 | 0.0140218 |
| SERTAD2 | SERTA domain containing 2 | 0.013905 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0138257 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0136591 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0136124 |
| KDM6B | lysine (K)-specific demethylase 6B | 0.0133042 |
| SLC30A10 | solute carrier family 30, member 10 | 0.0132508 |
| NUP50 | nucleoporin 50kDa | 0.013141 |
| PHF3 | PHD finger protein 3 | 0.0130344 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0128051 |
| SQSTM1 | sequestosome 1 | 0.01261 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0125426 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0124819 |
| BSG | basigin (Ok blood group) | 0.0124235 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0123655 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0123361 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.0123087 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | -0.130918 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0952549 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.083634 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0802733 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0687027 |
| TMSB10 | thymosin beta 10 | -0.0661728 |
| AREG | amphiregulin | -0.0591402 |
| RPS24 | ribosomal protein S24 | -0.0533927 |
| FERMT1 | fermitin family member 1 | -0.0504047 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0454674 |
| RPL35A | ribosomal protein L35a | -0.0453562 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0419083 |
| OXR1 | oxidation resistance 1 | -0.040001 |
| UBC | ubiquitin C | -0.0372509 |
| RPS27A | ribosomal protein S27a | -0.0354932 |
| RBM25 | RNA binding motif protein 25 | -0.0343293 |
| RPL34 | ribosomal protein L34 | -0.0301792 |
| S100A6 | S100 calcium binding protein A6 | -0.029004 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0289593 |
| AHNAK | AHNAK nucleoprotein | -0.0281281 |
| S100A10 | S100 calcium binding protein A10 | -0.0275744 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0275347 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0273934 |
| ACTG1 | actin gamma 1 | -0.02695 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.026156 |
| HDAC2 | histone deacetylase 2 | -0.0256119 |
| RPS21 | ribosomal protein S21 | -0.0252782 |
| RPL23 | ribosomal protein L23 | -0.0248772 |
| MTAP | methylthioadenosine phosphorylase | -0.0246343 |
| FHIT | fragile histidine triad | -0.0243484 |
| RNF43 | ring finger protein 43 | -0.0241676 |
| FRAS1 | Fraser extracellular matrix complex subunit 1 | -0.0234869 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0232254 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0230617 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0218141 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0215473 |
| RPL12 | ribosomal protein L12 | -0.0211985 |
| BMP4 | bone morphogenetic protein 4 | -0.0200191 |
| SERINC5 | serine incorporator 5 | -0.0198019 |
| RPS6 | ribosomal protein S6 | -0.0197743 |
| MT2A | metallothionein 2A | -0.0193655 |
| RPLP0 | ribosomal protein, large, P0 | -0.01886 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0186266 |
| RPS29 | ribosomal protein S29 | -0.0184571 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0177401 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0172924 |
| CCNI | cyclin I | -0.0172745 |
| NEMF | nuclear export mediator factor | -0.0170075 |
| PERP | PERP, TP53 apoptosis effector | -0.0166755 |
| TXNRD1 | thioredoxin reductase 1 | -0.0166447 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0162767 |
| CD9 | CD9 molecule | -0.0162415 |
| RPL5 | ribosomal protein L5 | -0.0162279 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.016041 |
| RAD51B | RAD51 paralog B | -0.0160275 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0159513 |
| CBX3 | chromobox homolog 3 | -0.0157338 |
| RPL32 | ribosomal protein L32 | -0.0157262 |
| RPL19 | ribosomal protein L19 | -0.0157259 |
| MT1X | metallothionein 1X | -0.0155429 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.0154295 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0153028 |
| SKAP1 | src kinase associated phosphoprotein 1 | -0.0151901 |
| ENO1 | enolase 1, (alpha) | -0.0150073 |
| RUNX2 | runt-related transcription factor 2 | -0.0148803 |
| EREG | epiregulin | -0.0147031 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.0145626 |
| S100A9 | S100 calcium binding protein A9 | -0.0144341 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0142919 |
| KLK10 | kallikrein-related peptidase 10 | -0.0141869 |
| ANLN | anillin, actin binding protein | -0.0141396 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0141344 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0141098 |
| HLA-B | major histocompatibility complex, class I, B | -0.0140945 |
| FOSL1 | FOS-like antigen 1 | -0.0140088 |
| RPS13 | ribosomal protein S13 | -0.0139733 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0138374 |
| RPL11 | ribosomal protein L11 | -0.01379 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0136555 |
| BCL2L1 | BCL2-like 1 | -0.0135555 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0135457 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0134167 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0132448 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0132206 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0131136 |
| TOP1 | topoisomerase (DNA) I | -0.0130103 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0129865 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.012838 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0127832 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0127405 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0126733 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0123266 |
| HMGB2 | high mobility group box 2 | -0.0123032 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.0122819 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0122663 |
| RPS28 | ribosomal protein S28 | -0.0121265 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0118202 |
| FAM3C | family with sequence similarity 3, member C | -0.0118106 |
| FAR1 | fatty acyl CoA reductase 1 | -0.011784 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0115646 |
