| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | endoplasmic reticulum to nucleus signaling 1|The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2081) |
| External Link | https://ncbi.nlm.nih.gov/gene/2081 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the ERN1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PCNA | proliferating cell nuclear antigen | 0.0192198 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0151067 |
| IFI44L | interferon-induced protein 44-like | 0.015058 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | 0.0129501 |
| MX1 | MX dynamin-like GTPase 1 | 0.0128348 |
| SCGB2A2 | secretoglobin, family 2A, member 2 | 0.0118265 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.0108401 |
| TYMS | thymidylate synthetase | 0.0107136 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0105171 |
| TNC | tenascin C | 0.0104336 |
| ABCC4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 | 0.0104109 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00988526 |
| LTF | lactotransferrin | 0.00983629 |
| CP | ceruloplasmin (ferroxidase) | 0.00956812 |
| KRT23 | keratin 23, type I | 0.0095526 |
| GOLGA8A | golgin A8 family, member A | 0.00953868 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00941747 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.00932922 |
| NNMT | nicotinamide N-methyltransferase | 0.00921619 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00920864 |
| RAB13 | RAB13, member RAS oncogene family | 0.00917521 |
| PCLAF | PCNA clamp associated factor | 0.00905712 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00891467 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.00883261 |
| BST2 | bone marrow stromal cell antigen 2 | 0.00879964 |
| PKM | pyruvate kinase, muscle | 0.00878363 |
| ACSL1 | acyl-CoA synthetase long-chain family member 1 | 0.00869549 |
| IRF7 | interferon regulatory factor 7 | 0.00862339 |
| KCNJ16 | potassium channel, inwardly rectifying subfamily J, member 16 | 0.00861211 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.00861026 |
| CLU | clusterin | 0.00860456 |
| ARNT2 | aryl-hydrocarbon receptor nuclear translocator 2 | 0.00859956 |
| FGB | fibrinogen beta chain | 0.00857011 |
| PTK2 | protein tyrosine kinase 2 | 0.00855117 |
| PLP2 | proteolipid protein 2 (colonic epithelium-enriched) | 0.00838584 |
| FXYD2 | FXYD domain containing ion transport regulator 2 | 0.00836811 |
| KLHL9 | kelch-like family member 9 | 0.00822413 |
| IFI44 | interferon-induced protein 44 | 0.00817875 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | 0.00816048 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.00809482 |
| MAOB | monoamine oxidase B | 0.00806127 |
| AQP1 | aquaporin 1 (Colton blood group) | 0.00797526 |
| ADM | adrenomedullin | 0.00796619 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.00795936 |
| SCGB1D2 | secretoglobin, family 1D, member 2 | 0.0078244 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00773187 |
| DEFB1 | defensin, beta 1 | 0.00767158 |
| BAG3 | BCL2-associated athanogene 3 | 0.00764319 |
| ASPH | aspartate beta-hydroxylase | 0.00758752 |
| SLC30A1 | solute carrier family 30 (zinc transporter), member 1 | 0.00748521 |
| C3 | complement component 3 | 0.00746437 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00740858 |
| SLC2A5 | solute carrier family 2 (facilitated glucose/fructose transporter), member 5 | 0.0073348 |
| DUSP5 | dual specificity phosphatase 5 | 0.0073253 |
| MT1H | metallothionein 1H | 0.00726348 |
| TRIM9 | tripartite motif containing 9 | 0.0072333 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00719976 |
| RHOB | ras homolog family member B | 0.00704771 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00701941 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.00699329 |
| SLBP | stem-loop binding protein | 0.00698885 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.00690958 |
| CRYAB | crystallin, alpha B | 0.00684692 |
| SOX9 | SRY (sex determining region Y)-box 9 | 0.00679793 |
| MX2 | MX dynamin-like GTPase 2 | 0.00673707 |
| MGLL | monoglyceride lipase | 0.00672134 |
| SLC4A1 | solute carrier family 4 (anion exchanger), member 1 (Diego blood group) | 0.00666168 |
| COMT | catechol-O-methyltransferase | 0.00666063 |
| MT1HL1 | metallothionein 1H-like 1 | 0.00665004 |
| HERC6 | HECT and RLD domain containing E3 ubiquitin protein ligase family member 6 | 0.00662996 |
| HBD | hemoglobin, delta | 0.00662586 |
| MT2A | metallothionein 2A | 0.00660123 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.00659819 |
| GRB7 | growth factor receptor-bound protein 7 | 0.00659012 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00657193 |
| OXTR | oxytocin receptor | 0.00656344 |
| GRAMD2B | GRAM domain containing 2B | 0.0064984 |
| KRT7 | keratin 7, type II | 0.0064949 |
| GPX3 | glutathione peroxidase 3 | 0.00648974 |
| MELK | maternal embryonic leucine zipper kinase | 0.00647957 |
| MFAP3L | microfibrillar-associated protein 3-like | 0.00642368 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.00637292 |
| XAF1 | XIAP associated factor 1 | 0.00635011 |
| TRIM22 | tripartite motif containing 22 | 0.00634785 |
| ADIRF | adipogenesis regulatory factor | 0.00634305 |
| GALNT14 | polypeptide N-acetylgalactosaminyltransferase 14 | 0.0063228 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 | 0.00632081 |
| CA12 | carbonic anhydrase XII | 0.00630675 |
| RAB4A | RAB4A, member RAS oncogene family | 0.00629806 |
| MAP3K7CL | MAP3K7 C-terminal like | 0.00629498 |
| SFXN3 | sideroflexin 3 | 0.00629208 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | 0.00626655 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.00625495 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00625432 |
| CDKN1A | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 0.00625077 |
| ZNF83 | zinc finger protein 83 | 0.00624396 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.00623513 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00623409 |
| TMX4 | thioredoxin-related transmembrane protein 4 | 0.00621311 |
| MAGEA3 | melanoma antigen family A3 | 0.00620333 |
| COL6A2 | collagen, type VI, alpha 2 | 0.00619904 |
| STK32B | serine/threonine kinase 32B | 0.00619276 |
| VDAC1 | voltage-dependent anion channel 1 | 0.00618772 |
| BEX4 | brain expressed, X-linked 4 | 0.00617791 |
| MT1E | metallothionein 1E | 0.00612771 |
| PLAUR | plasminogen activator, urokinase receptor | 0.00609853 |
| FN1 | fibronectin 1 | 0.00608461 |
| SIK1 | salt-inducible kinase 1 | 0.00607644 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 | 0.00607067 |
| CCNG2 | cyclin G2 | 0.00606523 |
| NOTCH2NL | notch 2 N-terminal like | 0.00605141 |
| HOXB2 | homeobox B2 | 0.0060487 |
| GATM | glycine amidinotransferase (L-arginine:glycine amidinotransferase) | 0.00601123 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0060034 |
| WDR1 | WD repeat domain 1 | 0.00599325 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.00597828 |
| RTN2 | reticulon 2 | 0.00597459 |
| PPP1R1A | protein phosphatase 1, regulatory (inhibitor) subunit 1A | 0.00596646 |
| NPAS2 | neuronal PAS domain protein 2 | 0.00596557 |
| NGFRAP1 | nerve growth factor receptor (TNFRSF16) associated protein 1 | 0.00596518 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.00595714 |
| EHHADH | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase | 0.00595662 |
| ZNF43 | zinc finger protein 43 | 0.00595444 |
| TGFB1 | transforming growth factor, beta 1 | 0.00594187 |
| ADAT1 | adenosine deaminase, tRNA-specific 1 | 0.00594007 |
| PAX5 | paired box 5 | 0.00593767 |
| SACS | sacsin molecular chaperone | 0.00593652 |
| GOLM1 | golgi membrane protein 1 | 0.00592038 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0059182 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.00591735 |
| HHEX | hematopoietically expressed homeobox | 0.00590126 |
| UROD | uroporphyrinogen decarboxylase | 0.00589493 |
| HP | haptoglobin | 0.00589263 |
| APOLD1 | apolipoprotein L domain containing 1 | 0.00588679 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.00586679 |
| DDX21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21 | 0.00586505 |
| KRT18 | keratin 18, type I | 0.00585386 |
| MT1X | metallothionein 1X | 0.00581395 |
| RASSF2 | Ras association (RalGDS/AF-6) domain family member 2 | 0.00579427 |
| PLTP | phospholipid transfer protein | 0.00578834 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00576334 |
| FKBP4 | FK506 binding protein 4, 59kDa | 0.00574067 |
| HOPX | HOP homeobox | 0.00572838 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.00571068 |
| RBM47 | RNA binding motif protein 47 | 0.00570891 |
| NUSAP1 | nucleolar and spindle associated protein 1 | 0.00569189 |
| C10ORF10 | chromosome 10 open reading frame 10 | 0.00569081 |
| TNFAIP6 | tumor necrosis factor, alpha-induced protein 6 | 0.00568904 |
| PKD2 | polycystic kidney disease 2 (autosomal dominant) | 0.00568544 |
| A2M | alpha-2-macroglobulin | 0.00568179 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | 0.00567288 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.00567246 |
| CSAD | cysteine sulfinic acid decarboxylase | 0.00566774 |
| MYBPC1 | myosin binding protein C, slow type | 0.00565015 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0056452 |
| STOM | stomatin | 0.00562068 |
| APOBEC3B | apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B | 0.00562036 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00561371 |
| ITPKB | inositol-trisphosphate 3-kinase B | 0.00559281 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00559079 |
| F5 | coagulation factor V (proaccelerin, labile factor) | 0.0055724 |
| CCDC86 | coiled-coil domain containing 86 | 0.00555066 |
| HAL | histidine ammonia-lyase | 0.00553859 |
| LAMA5 | laminin, alpha 5 | 0.00553157 |
| UBE2L6 | ubiquitin-conjugating enzyme E2L 6 | 0.00552894 |
| MITF | microphthalmia-associated transcription factor | 0.0055279 |
| ZNF512B | zinc finger protein 512B | 0.00551497 |
| ARMCX3 | armadillo repeat containing, X-linked 3 | 0.00551013 |
| DYNLT1 | dynein, light chain, Tctex-type 1 | 0.00550976 |
| SP110 | SP110 nuclear body protein | 0.0054991 |
| CXCR4 | chemokine (C-X-C motif) receptor 4 | 0.00547978 |
| TM4SF4 | transmembrane 4 L six family member 4 | 0.00547065 |
| NFIB | nuclear factor I/B | 0.00545661 |
| CHMP5 | charged multivesicular body protein 5 | 0.00544377 |
| MS4A3 | membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) | 0.00543881 |
| IL6R | interleukin 6 receptor | 0.00543571 |
| RHOF | ras homolog family member F (in filopodia) | 0.00543297 |
| FKBP11 | FK506 binding protein 11, 19 kDa | 0.00541576 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.00540038 |
| TFR2 | transferrin receptor 2 | 0.00539694 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.00539551 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00538837 |
| ARG1 | arginase 1 | 0.00538557 |
| ALOX5 | arachidonate 5-lipoxygenase | 0.00537524 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.00535809 |
| COL4A2 | collagen, type IV, alpha 2 | 0.00535721 |
| NPIPB3 | nuclear pore complex interacting protein family, member B3 | 0.00532633 |
| GNAS | GNAS complex locus | 0.00531436 |
| IRF8 | interferon regulatory factor 8 | 0.00529819 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.00529459 |
| TMEM140 | transmembrane protein 140 | 0.0052929 |
| RRM2 | ribonucleotide reductase M2 | 0.00529247 |
| PARP12 | poly (ADP-ribose) polymerase family, member 12 | 0.00526727 |
| MARCKSL1 | MARCKS-like 1 | 0.00526414 |
| YTHDF1 | YTH N(6)-methyladenosine RNA binding protein 1 | 0.0052447 |
| CA2 | carbonic anhydrase II | 0.00523914 |
| ALAS2 | 5'-aminolevulinate synthase 2 | 0.00522201 |
| DPP8 | dipeptidyl-peptidase 8 | 0.00520007 |
| GEM | GTP binding protein overexpressed in skeletal muscle | 0.00516626 |
| KRT17 | keratin 17, type I | 0.00516614 |
| SEC14L1 | SEC14-like 1 (S. cerevisiae) | 0.00516555 |
| TCF4 | transcription factor 4 | 0.00514371 |
| GSDME | gasdermin E | 0.00512206 |
| OBSL1 | obscurin-like 1 | 0.00510735 |
| RBM38 | RNA binding motif protein 38 | 0.00510164 |
| RCAN1 | regulator of calcineurin 1 | 0.00509732 |
| CAMK2N1 | calcium/calmodulin-dependent protein kinase II inhibitor 1 | 0.00509132 |
| CD37 | CD37 molecule | 0.00508588 |
| PKD1P1 | polycystic kidney disease 1 (autosomal dominant) pseudogene 1 | 0.00508349 |
| PGRMC2 | progesterone receptor membrane component 2 | 0.00508277 |
| RAB29 | RAB29, member RAS oncogene family | 0.00507987 |
| IMPDH2 | IMP (inosine 5'-monophosphate) dehydrogenase 2 | 0.0050769 |
| RAPSN | receptor-associated protein of the synapse | 0.00507172 |
| MFSD10 | major facilitator superfamily domain containing 10 | 0.0050711 |
| MET | MET proto-oncogene, receptor tyrosine kinase | 0.00506495 |
| ZYX | zyxin | 0.00505143 |
| MMD | monocyte to macrophage differentiation-associated | 0.0049968 |
| AHSP | alpha hemoglobin stabilizing protein | 0.00497811 |
| TIMM17B | translocase of inner mitochondrial membrane 17 homolog B (yeast) | 0.00497268 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00496542 |
| MBOAT7 | membrane bound O-acyltransferase domain containing 7 | 0.00495094 |
| PSMB8 | proteasome (prosome, macropain) subunit, beta type, 8 | 0.0049447 |
| PLK1 | polo-like kinase 1 | 0.00493955 |
| INHBB | inhibin, beta B | 0.0049365 |
| MICB | MHC class I polypeptide-related sequence B | 0.00493494 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.00493305 |
| LOX | lysyl oxidase | 0.00489668 |
| IFI35 | interferon-induced protein 35 | 0.0048787 |
| ZMAT3 | zinc finger, matrin-type 3 | 0.0048783 |
| EP300 | E1A binding protein p300 | 0.00487584 |
| SIGLEC15 | sialic acid binding Ig-like lectin 15 | 0.00486186 |
| CST6 | cystatin E/M | 0.0048595 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.00485681 |
| MMP9 | matrix metallopeptidase 9 | 0.00484985 |
| CTSA | cathepsin A | 0.00484827 |
| SLC38A1 | solute carrier family 38, member 1 | 0.004827 |
| RPS26 | ribosomal protein S26 | 0.00482038 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.00481844 |
| CD40 | CD40 molecule, TNF receptor superfamily member 5 | 0.00481586 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.00480149 |
| LONP2 | lon peptidase 2, peroxisomal | 0.004793 |
| PXDN | peroxidasin | 0.00478889 |
| MCAM | melanoma cell adhesion molecule | 0.0047774 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.00477733 |
| ZCCHC2 | zinc finger, CCHC domain containing 2 | 0.00476072 |
| ARHGAP6 | Rho GTPase activating protein 6 | 0.00474597 |
| TRIB3 | tribbles pseudokinase 3 | 0.00474588 |
| FIS1 | fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) | 0.0047432 |
| TOB1 | transducer of ERBB2, 1 | 0.00474218 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SFRP4 | secreted frizzled-related protein 4 | -0.0145517 |
| AGR2 | anterior gradient 2 | -0.0122306 |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | -0.012181 |
| OLFM4 | olfactomedin 4 | -0.0116087 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0104452 |
| DACH1 | dachshund family transcription factor 1 | -0.0100133 |
| GATA6 | GATA binding protein 6 | -0.0100013 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.00964712 |
| AKR1C2 | aldo-keto reductase family 1, member C2 | -0.00956511 |
| LEFTY1 | left-right determination factor 1 | -0.00952558 |
| MMP12 | matrix metallopeptidase 12 | -0.00922994 |
| CACNA2D2 | calcium channel, voltage-dependent, alpha 2/delta subunit 2 | -0.00883198 |
| CCNB1 | cyclin B1 | -0.00876951 |
| TSPAN8 | tetraspanin 8 | -0.00873405 |
| NDNF | neuron-derived neurotrophic factor | -0.00864899 |
| GPX2 | glutathione peroxidase 2 | -0.00852292 |
| CDC42 | cell division cycle 42 | -0.00843828 |
| AKR1C3 | aldo-keto reductase family 1, member C3 | -0.00837902 |
| EPB41L4B | erythrocyte membrane protein band 4.1 like 4B | -0.00823251 |
| CMAHP | cytidine monophospho-N-acetylneuraminic acid hydroxylase, pseudogene | -0.00816653 |
| PLAT | plasminogen activator, tissue | -0.00815617 |
| CES1 | carboxylesterase 1 | -0.00815014 |
| COL14A1 | collagen, type XIV, alpha 1 | -0.00806984 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | -0.00805798 |
| CTSZ | cathepsin Z | -0.00804273 |
| FBLN1 | fibulin 1 | -0.00799508 |
| ESRP1 | epithelial splicing regulatory protein 1 | -0.00799354 |
| TOX3 | TOX high mobility group box family member 3 | -0.00764961 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0076318 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.00760346 |
| PID1 | phosphotyrosine interaction domain containing 1 | -0.00759954 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.00751889 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog | -0.00749308 |
| GLUL | glutamate-ammonia ligase | -0.00747685 |
| DCN | decorin | -0.00744561 |
| TMC5 | transmembrane channel-like 5 | -0.00742742 |
| PLBD1 | phospholipase B domain containing 1 | -0.00738208 |
| HLA-DQA1 | major histocompatibility complex, class II, DQ alpha 1 | -0.00733401 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.00730473 |
| DUOX2 | dual oxidase 2 | -0.00727803 |
| ELN | elastin | -0.00721466 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0071996 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | -0.00705741 |
| C3ORF14 | chromosome 3 open reading frame 14 | -0.00704165 |
| ADH1C | alcohol dehydrogenase 1C (class I), gamma polypeptide | -0.0069192 |
| ESR1 | estrogen receptor 1 | -0.00690441 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00680516 |
| LGALS13 | lectin, galactoside-binding, soluble, 13 | -0.00678098 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.00675846 |
| LTBP2 | latent transforming growth factor beta binding protein 2 | -0.0067222 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | -0.00663163 |
| MYO1B | myosin IB | -0.00660839 |
| TBC1D31 | TBC1 domain family, member 31 | -0.00660039 |
| SDC1 | syndecan 1 | -0.00655635 |
| MAP7 | microtubule-associated protein 7 | -0.00655441 |
| NOX1 | NADPH oxidase 1 | -0.0065037 |
| EPHB2 | EPH receptor B2 | -0.00646015 |
| IRF6 | interferon regulatory factor 6 | -0.00643317 |
| ATP10B | ATPase, class V, type 10B | -0.00643072 |
| MDFIC | MyoD family inhibitor domain containing | -0.006415 |
| MMP3 | matrix metallopeptidase 3 | -0.00641251 |
| CERS6 | ceramide synthase 6 | -0.00640364 |
| CCP110 | centriolar coiled coil protein 110kDa | -0.00639901 |
| ZNF423 | zinc finger protein 423 | -0.0063811 |
| HPGD | hydroxyprostaglandin dehydrogenase 15-(NAD) | -0.00635997 |
| MUC4 | mucin 4, cell surface associated | -0.00635441 |
| TCF21 | transcription factor 21 | -0.00633588 |
| TSPYL5 | TSPY-like 5 | -0.00630089 |
| PKP2 | plakophilin 2 | -0.00628106 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | -0.00625814 |
| NSDHL | NAD(P) dependent steroid dehydrogenase-like | -0.00625128 |
| OGN | osteoglycin | -0.00622323 |
| ACP5 | acid phosphatase 5, tartrate resistant | -0.00622004 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.00618023 |
| FAM198B | family with sequence similarity 198, member B | -0.00613399 |
| DACT1 | dishevelled-binding antagonist of beta-catenin 1 | -0.00612809 |
| EPCAM | epithelial cell adhesion molecule | -0.00610374 |
| CLCA1 | chloride channel accessory 1 | -0.00609851 |
| PRELP | proline/arginine-rich end leucine-rich repeat protein | -0.00608527 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | -0.0060756 |
| CD1D | CD1d molecule | -0.00606569 |
| EGFL6 | EGF-like-domain, multiple 6 | -0.00603708 |
| NEBL | nebulette | -0.00603178 |
| FAM171A1 | family with sequence similarity 171, member A1 | -0.00600278 |
| AOC1 | amine oxidase, copper containing 1 | -0.00597882 |
| FBXO21 | F-box protein 21 | -0.00597224 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | -0.0059241 |
| DPYD | dihydropyrimidine dehydrogenase | -0.00589924 |
| CEACAM7 | carcinoembryonic antigen-related cell adhesion molecule 7 | -0.00589132 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00585538 |
| GTPBP8 | GTP-binding protein 8 (putative) | -0.00583885 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.00582339 |
| ITGBL1 | integrin, beta-like 1 (with EGF-like repeat domains) | -0.00581704 |
| ADH1B | alcohol dehydrogenase 1B (class I), beta polypeptide | -0.00580626 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.00579691 |
| HLA-DPA1 | major histocompatibility complex, class II, DP alpha 1 | -0.00579612 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00579353 |
| CCNA2 | cyclin A2 | -0.00578879 |
| EMP2 | epithelial membrane protein 2 | -0.00576001 |
| CDH1 | cadherin 1, type 1, E-cadherin (epithelial) | -0.00574094 |
| IFT57 | intraflagellar transport 57 | -0.00573499 |
| USP6NL | USP6 N-terminal like | -0.00568247 |
| BMI1 | BMI1 proto-oncogene, polycomb ring finger | -0.00564583 |
| TRIM36 | tripartite motif containing 36 | -0.0056211 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | -0.00561197 |
| ITGA4 | integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor) | -0.00560643 |
| GRK5 | G protein-coupled receptor kinase 5 | -0.00559569 |
| FZD5 | frizzled class receptor 5 | -0.00558813 |
| COL4A6 | collagen, type IV, alpha 6 | -0.00557565 |
| MYH11 | myosin, heavy chain 11, smooth muscle | -0.00553099 |
| ALDH1A3 | aldehyde dehydrogenase 1 family, member A3 | -0.00552216 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.00551738 |
| VANGL1 | VANGL planar cell polarity protein 1 | -0.00551629 |
| NCK1 | NCK adaptor protein 1 | -0.00544922 |
| KYNU | kynureninase | -0.0054425 |
| S100A8 | S100 calcium binding protein A8 | -0.00543645 |
| RIMS3 | regulating synaptic membrane exocytosis 3 | -0.00543461 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.00542577 |
| MRS2 | MRS2 magnesium transporter | -0.00539386 |
| YAP1 | Yes-associated protein 1 | -0.00538443 |
| FGL2 | fibrinogen-like 2 | -0.00537645 |
| GNAO1 | guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O | -0.00537193 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.00537151 |
| TFDP2 | transcription factor Dp-2 (E2F dimerization partner 2) | -0.00536949 |
| PSEN1 | presenilin 1 | -0.00536281 |
| ISLR | immunoglobulin superfamily containing leucine-rich repeat | -0.00535648 |
| SERINC5 | serine incorporator 5 | -0.00533607 |
| MECOM | MDS1 and EVI1 complex locus | -0.00531797 |
| EXOC5 | exocyst complex component 5 | -0.00531604 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | -0.00531556 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.00530281 |
| SAMHD1 | SAM domain and HD domain 1 | -0.00530097 |
| VLDLR | very low density lipoprotein receptor | -0.00529535 |
| TMEM14A | transmembrane protein 14A | -0.00529508 |
| CPB1 | carboxypeptidase B1 (tissue) | -0.00529182 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | -0.00528228 |
| HSD17B6 | hydroxysteroid (17-beta) dehydrogenase 6 | -0.00525266 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | -0.00524746 |
| PLXNA2 | plexin A2 | -0.00522262 |
| WLS | wntless Wnt ligand secretion mediator | -0.00522066 |
| CASP10 | caspase 10, apoptosis-related cysteine peptidase | -0.0052098 |
| PHKA1 | phosphorylase kinase, alpha 1 (muscle) | -0.00520554 |
| CASP1 | caspase 1, apoptosis-related cysteine peptidase | -0.00520035 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.00518188 |
| NAT1 | N-acetyltransferase 1 (arylamine N-acetyltransferase) | -0.00516347 |
| FBLN5 | fibulin 5 | -0.00514031 |
| TOX | thymocyte selection-associated high mobility group box | -0.00513081 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0051295 |
| IQGAP2 | IQ motif containing GTPase activating protein 2 | -0.005127 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.00512207 |
| COL16A1 | collagen, type XVI, alpha 1 | -0.00511952 |
| SPINK4 | serine peptidase inhibitor, Kazal type 4 | -0.0051087 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.00510854 |
| RNF43 | ring finger protein 43 | -0.00509111 |
| EFNB2 | ephrin-B2 | -0.00508218 |
| ATP11B | ATPase, class VI, type 11B | -0.00507799 |
| CCR2 | chemokine (C-C motif) receptor 2 | -0.00507576 |
| TAGLN | transgelin | -0.00507024 |
| CA4 | carbonic anhydrase IV | -0.00506882 |
| REG1B | regenerating islet-derived 1 beta | -0.0050577 |
| EHF | ets homologous factor | -0.00504624 |
| EXT2 | exostosin glycosyltransferase 2 | -0.00504428 |
| CEBPG | CCAAT/enhancer binding protein (C/EBP), gamma | -0.00503517 |
| PITRM1 | pitrilysin metallopeptidase 1 | -0.00502764 |
| CEP70 | centrosomal protein 70kDa | -0.00501726 |
| ASCL1 | achaete-scute family bHLH transcription factor 1 | -0.00501215 |
| CD2 | CD2 molecule | -0.00501133 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00500245 |
| NUDT21 | nudix (nucleoside diphosphate linked moiety X)-type motif 21 | -0.00499028 |
| PGC | progastricsin (pepsinogen C) | -0.00498708 |
| EFHD2 | EF-hand domain family, member D2 | -0.00498404 |
| BUB1 | BUB1 mitotic checkpoint serine/threonine kinase | -0.00498293 |
| GABRP | gamma-aminobutyric acid (GABA) A receptor, pi | -0.00497726 |
| KCTD12 | potassium channel tetramerization domain containing 12 | -0.00497509 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.00496985 |
| STK38L | serine/threonine kinase 38 like | -0.00496625 |
| OSR2 | odd-skipped related transciption factor 2 | -0.00495961 |
| SLC16A2 | solute carrier family 16, member 2 (thyroid hormone transporter) | -0.00495882 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.0049551 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | -0.00494987 |
| CCN2 | cellular communication network factor 2 | -0.00494432 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.00492142 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.00488806 |
| PENK | proenkephalin | -0.0048816 |
| CCL14 | chemokine (C-C motif) ligand 14 | -0.00486982 |
| COMP | cartilage oligomeric matrix protein | -0.00486914 |
| CLCA4 | chloride channel accessory 4 | -0.00485937 |
| SVIL | supervillin | -0.00485537 |
| NKX2-1 | NK2 homeobox 1 | -0.0048495 |
| CD1E | CD1e molecule | -0.00484841 |
| ITGAE | integrin, alpha E (antigen CD103, human mucosal lymphocyte antigen 1; alpha polypeptide) | -0.00483975 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | -0.00483814 |
| GATC | glutamyl-tRNA(Gln) amidotransferase, subunit C | -0.00483695 |
| WISP2 | WNT1 inducible signaling pathway protein 2 | -0.00483237 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0048273 |
| CALB1 | calbindin 1, 28kDa | -0.00480722 |
| FERMT1 | fermitin family member 1 | -0.00477829 |
| GIMAP6 | GTPase, IMAP family member 6 | -0.00477069 |
| HDAC4 | histone deacetylase 4 | -0.00476065 |
| CSTA | cystatin A (stefin A) | -0.00474714 |
| MPZL2 | myelin protein zero-like 2 | -0.00472916 |
| WFDC2 | WAP four-disulfide core domain 2 | -0.00472501 |
| LRRC49 | leucine rich repeat containing 49 | -0.00472377 |
| CANT1 | calcium activated nucleotidase 1 | -0.00471986 |
| CTSH | cathepsin H | -0.00471641 |
| TSPAN7 | tetraspanin 7 | -0.00471167 |
| PON3 | paraoxonase 3 | -0.00469173 |
| ADH5 | alcohol dehydrogenase 5 (class III), chi polypeptide | -0.00469019 |
| AEBP1 | AE binding protein 1 | -0.00468402 |
| DERL1 | derlin 1 | -0.00468038 |
| FDX1 | ferredoxin 1 | -0.00466933 |
| GNA14 | guanine nucleotide binding protein (G protein), alpha 14 | -0.00466458 |
| AUTS2 | autism susceptibility candidate 2 | -0.00466296 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00465713 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.00465654 |
| GPA33 | glycoprotein A33 (transmembrane) | -0.00465476 |
| SIGIRR | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain | -0.004641 |
| SGCB | sarcoglycan, beta (43kDa dystrophin-associated glycoprotein) | -0.00463966 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.00460796 |
| ACP6 | acid phosphatase 6, lysophosphatidic | -0.00460004 |
| COL4A5 | collagen, type IV, alpha 5 | -0.00459611 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.00459341 |
| MFAP2 | microfibrillar-associated protein 2 | -0.00458994 |
| NUP160 | nucleoporin 160kDa | -0.00458048 |
| AGPAT5 | 1-acylglycerol-3-phosphate O-acyltransferase 5 | -0.0045798 |
| FGFBP1 | fibroblast growth factor binding protein 1 | -0.00457533 |
| CYP39A1 | cytochrome P450, family 39, subfamily A, polypeptide 1 | -0.00456956 |
| DLGAP5 | discs, large (Drosophila) homolog-associated protein 5 | -0.00456501 |
| RSBN1 | round spermatid basic protein 1 | -0.00455608 |
| MFAP4 | microfibrillar-associated protein 4 | -0.00455259 |
| ASPN | asporin | -0.0045476 |
| HIPK3 | homeodomain interacting protein kinase 3 | -0.00452904 |
| TMEM35 | transmembrane protein 35 | -0.00452814 |
| SPAG1 | sperm associated antigen 1 | -0.00451778 |
| FOXA2 | forkhead box A2 | -0.00451768 |
| SERPINA5 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 | -0.00451504 |
| FBP1 | fructose-1,6-bisphosphatase 1 | -0.00450234 |
| SLC25A14 | solute carrier family 25 (mitochondrial carrier, brain), member 14 | -0.00449711 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.00447914 |
| CFTR | cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) | -0.00447531 |
| RAB23 | RAB23, member RAS oncogene family | -0.004469 |
| SIX1 | SIX homeobox 1 | -0.00446352 |
| CD8A | CD8a molecule | -0.00446127 |
| ZW10 | zw10 kinetochore protein | -0.00444895 |
| FXYD1 | FXYD domain containing ion transport regulator 1 | -0.0044483 |
| ISL1 | ISL LIM homeobox 1 | -0.00444421 |
| DIAPH2 | diaphanous-related formin 2 | -0.00444192 |
| PIGR | polymeric immunoglobulin receptor | -0.00444025 |
| PFKFB2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 | -0.00442555 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.00442353 |
