ERN1 Gene Set

Dataset Pathway Commons Protein-Protein Interactions
Category physical interactions
Type interacting protein
Description endoplasmic reticulum to nucleus signaling 1|The protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum-based stress signals. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2081)
External Link http://www.ncbi.nlm.nih.gov/gene/2081
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Genes

23 interacting proteins for ERN1 from the Pathway Commons Protein-Protein Interactions dataset.

Symbol Name
AGFG1 ArfGAP with FG repeats 1
BAK1 BCL2-antagonist/killer 1
BAX BCL2-associated X protein
COPS5 COP9 signalosome subunit 5
DERL1 derlin 1
DERL3 derlin 3
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSPA1B heat shock 70kDa protein 1B
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
MAP3K5 mitogen-activated protein kinase kinase kinase 5
PSEN1 presenilin 1
PSEN2 presenilin 2
RNF13 ring finger protein 13
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SRPK2 SRSF protein kinase 2
SYVN1 synovial apoptosis inhibitor 1, synoviolin
TAOK3 TAO kinase 3
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TRAF2 TNF receptor-associated factor 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
UBA52 ubiquitin A-52 residue ribosomal protein fusion product 1
UBC ubiquitin C
USP14 ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase)