ERP29 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description endoplasmic reticulum protein 29|This gene encodes a reticuloplasmin, a protein which resides in the lumen of the endoplasmic reticulum (ER). The protein shows sequence similarity to the protein disulfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, suggesting that this protein does not function as a disulfide isomerase. The protein dimerizes and is thought to play a role in the processing of secretory proteins within the ER. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 10961)
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Genes

325 genes differentially expressed following the ERP29 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
SLC22A14 solute carrier family 22, member 14 2.22333
PGAM4 phosphoglycerate mutase family member 4 2.22333
MUC6 mucin 6, oligomeric mucus/gel-forming 2.22333
FOXA1 forkhead box A1 2.22333
TMEM151A transmembrane protein 151A 2.22333
CASP4 caspase 4, apoptosis-related cysteine peptidase 2.22333
RASSF10 Ras association (RalGDS/AF-6) domain family (N-terminal) member 10 2.22333
CCDC62 coiled-coil domain containing 62 2.22333
GJB5 gap junction protein, beta 5, 31.1kDa 2.22333
LMO2 LIM domain only 2 (rhombotin-like 1) 2.22333
NFAM1 NFAT activating protein with ITAM motif 1 2.22333
TAS2R1 taste receptor, type 2, member 1 2.22333
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 2.22333
PLIN4 perilipin 4 2.22333
TMPRSS11A transmembrane protease, serine 11A 2.22333
COL20A1 collagen, type XX, alpha 1 2.22333
CHADL chondroadherin-like 2.22333
NPAP1 nuclear pore associated protein 1 2.22333
FAM167A family with sequence similarity 167, member A 2.22333
ZNF492 zinc finger protein 492 2.22333
OR52H1 olfactory receptor, family 52, subfamily H, member 1 2.22333
NPPC natriuretic peptide C 2.22333
ALOX15 arachidonate 15-lipoxygenase 2.22333
CD19 CD19 molecule 2.22333
CELF6 CUGBP, Elav-like family member 6 2.22333
MYOM3 myomesin 3 2.22333
GIMAP7 GTPase, IMAP family member 7 2.22333
MYO1G myosin IG 2.22333
CLEC14A C-type lectin domain family 14, member A 2.22333
TMC8 transmembrane channel-like 8 2.22333
SPX spexin hormone 2.22333
HMX3 H6 family homeobox 3 2.22333
PRR22 proline rich 22 2.22333
NWD2 NACHT and WD repeat domain containing 2 2.22333
LHX6 LIM homeobox 6 2.22333
ERAP2 endoplasmic reticulum aminopeptidase 2 2.22333
BTBD16 BTB (POZ) domain containing 16 2.22333
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1 2.22333
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 2.22333
OXT oxytocin/neurophysin I prepropeptide 2.22333
CACNG1 calcium channel, voltage-dependent, gamma subunit 1 2.22333
HPGD hydroxyprostaglandin dehydrogenase 15-(NAD) 2.22333
TDRD6 tudor domain containing 6 2.22333
ZWILCH zwilch kinetochore protein 2.22333
RLN3 relaxin 3 2.22333
ACVRL1 activin A receptor type II-like 1 2.22333
C8ORF74 chromosome 8 open reading frame 74 2.22333
YY2 YY2 transcription factor 2.22333
TCP11 t-complex 11, testis-specific 2.22333
TMEM121 transmembrane protein 121 2.22333
LBX2 ladybird homeobox 2 2.22333
SPDEF SAM pointed domain containing ETS transcription factor 2.22333
SPATA31G1 SPATA31 subfamily G member 1 2.22333
NFIX nuclear factor I/X (CCAAT-binding transcription factor) 2.22333
SPATS1 spermatogenesis associated, serine-rich 1 2.22333
GBP2 guanylate binding protein 2, interferon-inducible 2.22333
MCHR1 melanin-concentrating hormone receptor 1 2.22333
GPX6 glutathione peroxidase 6 2.22333
ZNF524 zinc finger protein 524 2.22333
TMPRSS3 transmembrane protease, serine 3 2.22333
KLB klotho beta 2.22333
WDR64 WD repeat domain 64 2.22333
TMEM40 transmembrane protein 40 2.22333
ASB9 ankyrin repeat and SOCS box containing 9 2.22333
PHF24 PHD finger protein 24 2.22333
H2BC1 H2B clustered histone 1 2.22333
ACKR5 atypical chemokine receptor 5 2.22333
SAXO5 stabilizer of axonemal microtubules 5 2.22333
CIROZ ciliated left-right organizer protein containing ZP-N domains 2.22333
SLC67A1 solute carrier family 67 member 1 2.22333
WASL-DT WASL divergent transcript 2.22333
CIMAP1D CIMAP1 family member D 2.22333
TENT5D terminal nucleotidyltransferase 5D 2.22333
DNAAF8 dynein axonemal assembly factor 8 2.22333
G6PC1 glucose-6-phosphatase catalytic subunit 1 2.22333
TTLL13 tubulin tyrosine ligase like 13 2.22333
CFAP65 cilia and flagella associated protein 65 2.22333
CEP85 centrosomal protein 85kDa 2.22333
TSPAN1 tetraspanin 1 2.22333
TBX6 T-box 6 2.22333
RNF113B ring finger protein 113B 2.22333
SLC45A2 solute carrier family 45, member 2 2.22333
TLR8 toll-like receptor 8 2.22333
TLR7 toll-like receptor 7 2.22333
TACSTD2 tumor-associated calcium signal transducer 2 2.22333
COL6A6 collagen, type VI, alpha 6 2.22333
TUBA3E tubulin, alpha 3e 2.22333
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) 2.22333
PCDHA8 protocadherin alpha 8 2.22333
RAB41 RAB41, member RAS oncogene family 2.22333
C1QTNF2 C1q and tumor necrosis factor related protein 2 2.22333
SLC12A3 solute carrier family 12 (sodium/chloride transporter), member 3 2.22333
OR52E5 olfactory receptor, family 52, subfamily E, member 5 2.22333
OR51M1 olfactory receptor, family 51, subfamily M, member 1 2.22333
ARMCX5-GPRASP2 ARMCX5-GPRASP2 readthrough 2.22333
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 2.22333
GATA2 GATA binding protein 2 2.22333
PNPLA1 patatin-like phospholipase domain containing 1 2.22333
FAM131C family with sequence similarity 131, member C 2.22333
VCX3B variable charge, X-linked 3B 2.22333
BARX2 BARX homeobox 2 2.22333
TACR2 tachykinin receptor 2 2.22333
STK26 serine/threonine protein kinase 26 2.22333
SLC22A10 solute carrier family 22, member 10 2.22333
HBE1 hemoglobin, epsilon 1 2.22333
CYS1 cystin 1 2.22333
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2 2.22333
C22ORF42 chromosome 22 open reading frame 42 2.22333
RASGRP4 RAS guanyl releasing protein 4 2.22333
OR52K1 olfactory receptor, family 52, subfamily K, member 1 2.22333
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 2.22333
CDK20 cyclin-dependent kinase 20 2.22333
ANKS4B ankyrin repeat and sterile alpha motif domain containing 4B 2.22333
EMILIN1 elastin microfibril interfacer 1 2.22333
FBXO47 F-box protein 47 2.22333
PEBP4 phosphatidylethanolamine-binding protein 4 2.22333
CDH15 cadherin 15, type 1, M-cadherin (myotubule) 2.22333
EDN2 endothelin 2 2.22333
CST4 cystatin S 2.22333
RSPH10B2 radial spoke head 10 homolog B2 (Chlamydomonas) 2.22333
CGB2 chorionic gonadotropin, beta polypeptide 2 2.22333
KLF4 Kruppel-like factor 4 (gut) 2.22333
PBK PDZ binding kinase 2.22333
CAMK2B calcium/calmodulin-dependent protein kinase II beta 2.22333
PRM1 protamine 1 2.22333
NPFFR1 neuropeptide FF receptor 1 2.22333
SLC6A12 solute carrier family 6 (neurotransmitter transporter), member 12 2.22333
FAM135B family with sequence similarity 135, member B 2.22333
CLRN1 clarin 1 2.22333
HLA-DOB major histocompatibility complex, class II, DO beta 2.22333
ITGA8 integrin, alpha 8 2.22333
NKX6-3 NK6 homeobox 3 2.22333
NKX6-2 NK6 homeobox 2 2.22333
GLDN gliomedin 2.22333
ERVV-2 endogenous retrovirus group V, member 2 2.22333
ERVV-1 endogenous retrovirus group V, member 1 2.22333
ETV3L ets variant 3-like 2.22333
BRIP1 BRCA1 interacting protein C-terminal helicase 1 2.22333
ADRA2A adrenoceptor alpha 2A 2.22333
VMO1 vitelline membrane outer layer 1 homolog (chicken) 2.22333
LOXHD1 lipoxygenase homology domains 1 2.22333
CFAP126 cilia and flagella associated protein 126 2.22333
PRR35 proline rich 35 2.22333
ARL13A ADP-ribosylation factor-like 13A 2.22333
ANKRD53 ankyrin repeat domain 53 2.22333
TPPP2 tubulin polymerization-promoting protein family member 2 2.22333
SMIM13 small integral membrane protein 13 2.22333
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 2.22333
DMRT1 doublesex and mab-3 related transcription factor 1 2.22333
PNLIP pancreatic lipase 2.22333
NCR3 natural cytotoxicity triggering receptor 3 2.22333
CSF1R colony stimulating factor 1 receptor 2.22333
UFSP1 UFM1-specific peptidase 1 (non-functional) 2.22333
WFDC13 WAP four-disulfide core domain 13 2.22333
SLC51B solute carrier family 51, beta subunit 2.22333
GSTM5 glutathione S-transferase mu 5 2.22333
ACTR3C ARP3 actin-related protein 3 homolog C (yeast) 2.22333
LIMS3 LIM and senescent cell antigen-like domains 3 2.22333
TBC1D28 TBC1 domain family, member 28 2.22333
PTGDR prostaglandin D2 receptor (DP) 2.22333
ECM1 extracellular matrix protein 1 2.22333
OR4D10 olfactory receptor, family 4, subfamily D, member 10 2.22333
ACSM1 acyl-CoA synthetase medium-chain family member 1 2.22333
RUFY4 RUN and FYVE domain containing 4 2.22333
IER5L immediate early response 5-like 2.22333
CLCNKA chloride channel, voltage-sensitive Ka 2.22333
CLCNKB chloride channel, voltage-sensitive Kb 2.22333
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 2.22333
FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a) 2.22333
TMEM52B transmembrane protein 52B 2.22333
KLHL26 kelch-like family member 26 2.22333
CLNK cytokine-dependent hematopoietic cell linker 2.22333
ALG12 ALG12, alpha-1,6-mannosyltransferase 2.22333
NXF3 nuclear RNA export factor 3 2.22333
ANXA1 annexin A1 2.22333
PPP1R3G protein phosphatase 1, regulatory subunit 3G 2.22333
SLX1A SLX1 structure-specific endonuclease subunit homolog A (S. cerevisiae) 2.22333
TGM7 transglutaminase 7 2.22333
TTC36 tetratricopeptide repeat domain 36 2.22333
IL12A interleukin 12A 2.22333
FCN3 ficolin (collagen/fibrinogen domain containing) 3 2.22333
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 2.22333
CLEC7A C-type lectin domain family 7, member A 2.22333
APOH apolipoprotein H (beta-2-glycoprotein I) 2.22333
RPA4 replication protein A4, 30kDa 2.22333
LRRC32 leucine rich repeat containing 32 2.22333
HSPB2 heat shock 27kDa protein 2 2.22333
TMEM132E transmembrane protein 132E 2.22333
TCF21 transcription factor 21 2.22333
ACOX2 acyl-CoA oxidase 2, branched chain 2.22333
TRPM8 transient receptor potential cation channel, subfamily M, member 8 2.22333
KCNK3 potassium channel, two pore domain subfamily K, member 3 2.22333
APLNR apelin receptor 2.22333
GCH1 GTP cyclohydrolase 1 2.1788
VPS13C vacuolar protein sorting 13 homolog C (S. cerevisiae) 2.14294
GRB14 growth factor receptor-bound protein 14 2.14294
MALSU1 mitochondrial assembly of ribosomal large subunit 1 2.13916
CNPPD1 cyclin Pas1/PHO80 domain containing 1 2.13201
FGF12 fibroblast growth factor 12 2.11785
C2CD4D C2 calcium-dependent domain containing 4D 2.10086
CDH12 cadherin 12, type 2 (N-cadherin 2) 2.10086
ATP6V1G2 ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 2.10086
UBA5 ubiquitin-like modifier activating enzyme 5 2.06707
DISP1 dispatched homolog 1 (Drosophila) 2.06394
ANGEL1 angel homolog 1 (Drosophila) 2.05832
BOLA3 bolA family member 3 2.01949
STAU2 staufen double-stranded RNA binding protein 2 2.01949
ARFRP1 ADP-ribosylation factor related protein 1 2.01949
ATP5ME ATP synthase membrane subunit e 2.01949
PEX11B peroxisomal biogenesis factor 11 beta 2.01949
SFSWAP splicing factor, suppressor of white-apricot family 2.01949
VPS8 vacuolar protein sorting 8 homolog (S. cerevisiae) 2.01949
ACADSB acyl-CoA dehydrogenase, short/branched chain 2.01949
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box) 2.01949
DACH1 dachshund family transcription factor 1 2.01949
LRRN3 leucine rich repeat neuronal 3 2.01949
SUOX sulfite oxidase 2.01184
ANKRD18A ankyrin repeat domain 18A 2.01027
TRMO tRNA methyltransferase O 2.00957
CAPS2 calcyphosine 2 2.00401

decreased expression

Symbol Name Standardized Value
AFG2A AFG2 AAA ATPase homolog A -2.22333
BTN3A3 butyrophilin, subfamily 3, member A3 -2.22333
FREM2 FRAS1 related extracellular matrix protein 2 -2.22333
IL17RC interleukin 17 receptor C -2.22333
TSEN15 TSEN15 tRNA splicing endonuclease subunit -2.22333
RBM7 RNA binding motif protein 7 -2.22333
ADAMTSL3 ADAMTS-like 3 -2.22333
TDRD1 tudor domain containing 1 -2.22333
TMEM219 transmembrane protein 219 -2.22333
CRIP2 cysteine-rich protein 2 -2.22333
RNF8 ring finger protein 8, E3 ubiquitin protein ligase -2.22333
STK36 serine/threonine kinase 36 -2.22333
RUMY2 RUMY family member 2 -2.22333
MEIOB meiosis specific with OB domains -2.22333
DGAT2 diacylglycerol O-acyltransferase 2 -2.22333
IGFBPL1 insulin-like growth factor binding protein-like 1 -2.22333
CPNE4 copine IV -2.22333
MARCHF11 membrane associated ring-CH-type finger 11 -2.22333
MARCHF9 membrane associated ring-CH-type finger 9 -2.22333
ZNF527 zinc finger protein 527 -2.22333
RIPK4 receptor-interacting serine-threonine kinase 4 -2.22333
STX16 syntaxin 16 -2.22333
GRID2 glutamate receptor, ionotropic, delta 2 -2.22333
NBPF14 neuroblastoma breakpoint family, member 14 -2.22333
MRPS35 mitochondrial ribosomal protein S35 -2.22333
GLI4 GLI family zinc finger 4 -2.22333
RNMT RNA (guanine-7-) methyltransferase -2.22333
PRRT3 proline-rich transmembrane protein 3 -2.22333
RNF212B ring finger protein 212B -2.22333
DEPDC7 DEP domain containing 7 -2.22333
CAPN12 calpain 12 -2.22333
CLPSL1 colipase-like 1 -2.22333
PPFIBP1 PTPRF interacting protein, binding protein 1 (liprin beta 1) -2.22333
IGFBP2 insulin-like growth factor binding protein 2, 36kDa -2.22333
RNFT1 ring finger protein, transmembrane 1 -2.22333
PDGFRA platelet-derived growth factor receptor, alpha polypeptide -2.22333
MAPK13 mitogen-activated protein kinase 13 -2.22333
CALY calcyon neuron-specific vesicular protein -2.22333
ERP29 endoplasmic reticulum protein 29 -2.22333
SEL1L sel-1 suppressor of lin-12-like (C. elegans) -2.22333
DACT2 dishevelled-binding antagonist of beta-catenin 2 -2.22333
CHMP4B charged multivesicular body protein 4B -2.22333
TTC14 tetratricopeptide repeat domain 14 -2.22333
SLC10A1 solute carrier family 10 (sodium/bile acid cotransporter), member 1 -2.19072
DHDH dihydrodiol dehydrogenase (dimeric) -2.19072
C3ORF62 chromosome 3 open reading frame 62 -2.19072
BCL2L10 BCL2-like 10 (apoptosis facilitator) -2.19072
BCL2L1 BCL2-like 1 -2.18657
MED19 mediator complex subunit 19 -2.18158
CCK cholecystokinin -2.14294
YAF2 YY1 associated factor 2 -2.13415
ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif, 16 -2.13415
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) -2.11785
TRA2B transformer 2 beta homolog (Drosophila) -2.11497
PTPN1 protein tyrosine phosphatase, non-receptor type 1 -2.11426
ANKRD36B ankyrin repeat domain 36B -2.09817
REXO2 RNA exonuclease 2 -2.07839
BRD8 bromodomain containing 8 -2.07765
TYW5 tRNA-yW synthesizing protein 5 -2.05873
VKORC1 vitamin K epoxide reductase complex, subunit 1 -2.05269
POU3F4 POU class 3 homeobox 4 -2.01949
TTC26 tetratricopeptide repeat domain 26 -2.01949
CCDC121 coiled-coil domain containing 121 -2.01949
TXNL4A thioredoxin-like 4A -2.01949
NKPD1 NTPase, KAP family P-loop domain containing 1 -2.01949
ACACA acetyl-CoA carboxylase alpha -2.01949
PPOX protoporphyrinogen oxidase -2.01949
PADI2 peptidyl arginine deiminase, type II -2.01949
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2 -2.01949
GPM6B glycoprotein M6B -2.01949
IMPG1 interphotoreceptor matrix proteoglycan 1 -2.01949
CARMIL3 capping protein regulator and myosin 1 linker 3 -2.01949
TICRR TOPBP1-interacting checkpoint and replication regulator -2.01949
DNAI7 dynein axonemal intermediate chain 7 -2.01949
GPR68 G protein-coupled receptor 68 -2.01949
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b -2.01949
UNC93A unc-93 homolog A (C. elegans) -2.01949
CRYAB crystallin, alpha B -2.01949
SLC22A1 solute carrier family 22 (organic cation transporter), member 1 -2.01949
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3 -2.01949
TIE1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 -2.01949
SLC16A11 solute carrier family 16, member 11 -2.01949
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila) -2.01949
MOGAT3 monoacylglycerol O-acyltransferase 3 -2.01949
LRRC59 leucine rich repeat containing 59 -2.01949
MBOAT4 membrane bound O-acyltransferase domain containing 4 -2.01949
NPPA natriuretic peptide A -2.01949
MAN1B1 mannosidase, alpha, class 1B, member 1 -2.01949
ANK3 ankyrin 3, node of Ranvier (ankyrin G) -2.01949
ARHGEF15 Rho guanine nucleotide exchange factor (GEF) 15 -2.01949
DUSP26 dual specificity phosphatase 26 (putative) -2.01949
TOR4A torsin family 4, member A -2.01949
JAG2 jagged 2 -2.01949
SMKR1 small lysine-rich protein 1 -2.01949
FLT3LG fms-related tyrosine kinase 3 ligand -2.01949
TMC2 transmembrane channel-like 2 -2.01949
CATSPERD catsper channel auxiliary subunit delta -2.01949
LDHAL6A lactate dehydrogenase A-like 6A -2.01949
EDF1 endothelial differentiation-related factor 1 -2.01949
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) -2.01949
HDAC3 histone deacetylase 3 -2.01949
ZNF471 zinc finger protein 471 -2.01949
NFE2L1 nuclear factor, erythroid 2-like 1 -2.01949
ANO7 anoctamin 7 -2.00826
TMED7 transmembrane emp24 protein transport domain containing 7 -2.00474