ESC/E(Z) complex Gene Set

Dataset	GO Cellular Component Annotations 2023
Category	structural or functional annotations
Type	biological process
Description	A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4. (Gene Ontology, GO_0035098)
External Link	http://amigo.geneontology.org/amigo/term/GO:0035098
Similar Terms
Downloads & Tools

Genes

8 proteins localized to the ESC/E(Z) complex cellular component from the curated GO Cellular Component Annotations 2023 dataset.

Symbol	Name
AEBP2	AE binding protein 2
EED	embryonic ectoderm development
EZH1	enhancer of zeste 1 polycomb repressive complex 2 subunit
EZH2	enhancer of zeste 2 polycomb repressive complex 2 subunit
HDAC2	histone deacetylase 2
RBBP4	retinoblastoma binding protein 4
RBBP7	retinoblastoma binding protein 7
SUZ12	SUZ12 polycomb repressive complex 2 subunit