ESC/E(Z) complex Gene Set
Dataset
GO Cellular Component Annotations 2025
Category
structural or functional annotations
Type
cellular component
Description
A multimeric protein complex that can methylate lysine-27 and lysine-9 residues of histone H3. In Drosophila the core subunits of the complex include ESC, E(Z), CAF1 (NURF-55) and SU(Z)12. In mammals the core subunits of the complex include EED, EZH2, SUZ12 and RBBP4. (Gene Ontology , GO_0035098 )
External Link
http://amigo.geneontology.org/amigo/term/GO:0035098
Similar Terms
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Genes
14 proteins localized to the ESC/E(Z) complex cellular component from the curated GO Cellular Component Annotations 2025 dataset.
Symbol
Name
AEBP2
AE binding protein 2
DNMT3L
DNA (cytosine-5-)-methyltransferase 3-like
EED
embryonic ectoderm development
EZH1
enhancer of zeste 1 polycomb repressive complex 2 subunit
EZH2
enhancer of zeste 2 polycomb repressive complex 2 subunit
HDAC2
histone deacetylase 2
MTF2
metal response element binding transcription factor 2
PHF1
PHD finger protein 1
PHF19
PHD finger protein 19
RBBP4
retinoblastoma binding protein 4
RBBP7
retinoblastoma binding protein 7
SIRT1
sirtuin 1
SUZ12
SUZ12 polycomb repressive complex 2 subunit
TRIM37
tripartite motif containing 37
