ESCO1 Gene Set

Dataset CM4AI KOLF21J CRISPRi Gene Perturbation Atlas
Category transcriptomics
Type gene perturbation
Description establishment of sister chromatid cohesion N-acetyltransferase 1|ESCO1 belongs to a conserved family of acetyltransferases involved in sister chromatid cohesion (Hou and Zou, 2005 [PubMed 15958495]).[supplied by OMIM, Mar 2008] (NCBI Entrez Gene Database, 114799)
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Genes

318 genes differentially expressed following the ESCO1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

increased expression

Symbol Name Standardized Value
PNMA5 paraneoplastic Ma antigen family member 5 2.59925
PCDHGA2 protocadherin gamma subfamily A, 2 2.59925
YIPF7 Yip1 domain family, member 7 2.59925
GNRHR gonadotropin-releasing hormone receptor 2.59925
ACSM5 acyl-CoA synthetase medium-chain family member 5 2.59925
OC90 otoconin 90 2.59925
CARD18 caspase recruitment domain family, member 18 2.59925
GPR33 G protein-coupled receptor 33 (gene/pseudogene) 2.59925
USP26 ubiquitin specific peptidase 26 2.59925
CMTM5 CKLF-like MARVEL transmembrane domain containing 5 2.59925
STMN4 stathmin-like 4 2.59925
IGFL2 IGF-like family member 2 2.59925
APOBEC3H apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H 2.59925
RNASE11 ribonuclease, RNase A family, 11 (non-active) 2.59925
SH2D7 SH2 domain containing 7 2.59925
REELD1 reeler domain containing 1 2.59925
TMEM255A transmembrane protein 255A 2.59925
GBX2 gastrulation brain homeobox 2 2.59925
SERPINB3 serpin peptidase inhibitor, clade B (ovalbumin), member 3 2.59925
SDSL serine dehydratase-like 2.59925
PLA2G10 phospholipase A2, group X 2.59925
LKAAEAR1 LKAAEAR motif containing 1 2.59925
PIK3R6 phosphoinositide-3-kinase, regulatory subunit 6 2.59925
SIGLEC1 sialic acid binding Ig-like lectin 1, sialoadhesin 2.5642
SFTPD surfactant protein D 2.5642
GJA10 gap junction protein, alpha 10, 62kDa 2.5642
FAM9C family with sequence similarity 9, member C 2.5642
TRPV2 transient receptor potential cation channel, subfamily V, member 2 2.5642
ADGB androglobin 2.5642
TMPRSS3 transmembrane protease, serine 3 2.5642
OLIG3 oligodendrocyte transcription factor 3 2.5642
TNIP3 TNFAIP3 interacting protein 3 2.5642
MYOM3 myomesin 3 2.5642
SULT6B1 sulfotransferase family, cytosolic, 6B, member 1 2.5642
C3ORF22 chromosome 3 open reading frame 22 2.5642
LGALS9 lectin, galactoside-binding, soluble, 9 2.5642
MRC1 mannose receptor, C type 1 2.5642
HMX1 H6 family homeobox 1 2.5642
CRYGC crystallin, gamma C 2.5642
MISP mitotic spindle positioning 2.5642
HTRA4 HtrA serine peptidase 4 2.5642
PHF24 PHD finger protein 24 2.5642
ANGPTL8 angiopoietin like 8 2.5642
IL18R1 interleukin 18 receptor 1 2.5642
MEIKIN meiotic kinetochore factor 2.5642
SLC28A3 solute carrier family 28 (concentrative nucleoside transporter), member 3 2.5642
TRPC5OS TRPC5 opposite strand 2.5642
PNLDC1 poly(A)-specific ribonuclease (PARN)-like domain containing 1 2.5642
PLXNB3 plexin B3 2.5642
CXORF65 chromosome X open reading frame 65 2.5642
GPR83 G protein-coupled receptor 83 2.5642
TAS2R3 taste receptor, type 2, member 3 2.5642
FRK fyn-related Src family tyrosine kinase 2.5642
COX7A1 cytochrome c oxidase subunit VIIa polypeptide 1 (muscle) 2.5642
STARD6 StAR-related lipid transfer (START) domain containing 6 2.5642
PCDHA2 protocadherin alpha 2 2.5642
TLE6 transducin-like enhancer of split 6 2.5642
PCDHB13 protocadherin beta 13 2.5642
PTGDR2 prostaglandin D2 receptor 2 2.5642
NXPE1 neurexophilin and PC-esterase domain family, member 1 2.5642
CHRD chordin 2.5642
THPO thrombopoietin 2.5642
EXOC3L4 exocyst complex component 3-like 4 2.5642
ARHGAP1 Rho GTPase activating protein 1 2.5642
INSRR insulin receptor-related receptor 2.5642
EEF2K eukaryotic elongation factor 2 kinase 2.5642
NPIPB9 nuclear pore complex interacting protein family, member B9 2.5642
SOX1 SRY (sex determining region Y)-box 1 2.5642
MYBPHL myosin binding protein H-like 2.5642
EGFLAM EGF-like, fibronectin type III and laminin G domains 2.5642
OSR2 odd-skipped related transciption factor 2 2.5642
ZNF705A zinc finger protein 705A 2.5642
HES3 hes family bHLH transcription factor 3 2.5642
HES7 hes family bHLH transcription factor 7 2.5642
TM4SF5 transmembrane 4 L six family member 5 2.5642
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 2.5642
THAP3 THAP domain containing, apoptosis associated protein 3 2.5642
TRIM10 tripartite motif containing 10 2.5642
SCGB3A1 secretoglobin, family 3A, member 1 2.5642
MS4A3 membrane-spanning 4-domains, subfamily A, member 3 (hematopoietic cell-specific) 2.5642
FUCA1 fucosidase, alpha-L- 1, tissue 2.5642
ANKRD13A ankyrin repeat domain 13A 2.5642
CPXCR1 CPX chromosome region, candidate 1 2.5642
SLC26A7 solute carrier family 26 (anion exchanger), member 7 2.5642
OR52H1 olfactory receptor, family 52, subfamily H, member 1 2.5642
COLEC10 collectin sub-family member 10 (C-type lectin) 2.5642
ZNF503 zinc finger protein 503 2.5642
PGC progastricsin (pepsinogen C) 2.5642
HRG histidine-rich glycoprotein 2.5642
ITGBL1 integrin, beta-like 1 (with EGF-like repeat domains) 2.5642
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1 2.5642
H4C4 H4 clustered histone 4 2.5642
PSKH2 protein serine kinase H2 2.5642
CIMAP1D CIMAP1 family member D 2.5642
PCDHGA4 protocadherin gamma subfamily A, 4 2.5642
WNT7B wingless-type MMTV integration site family, member 7B 2.5642
SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 2.5642
TBC1D3L TBC1 domain family, member 3L 2.5642
C11ORF16 chromosome 11 open reading frame 16 2.5642
ADAM7 ADAM metallopeptidase domain 7 2.5642
KLHL6 kelch-like family member 6 2.5642
GRK1 G protein-coupled receptor kinase 1 2.5642
S100A14 S100 calcium binding protein A14 2.5642
ADORA3 adenosine A3 receptor 2.5642
TSLP thymic stromal lymphopoietin 2.5642
CRYBB2 crystallin, beta B2 2.5642
NOX1 NADPH oxidase 1 2.5642
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6 2.5642
EGR2 early growth response 2 2.5642
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1 2.5642
NKX6-2 NK6 homeobox 2 2.5642
C1ORF105 chromosome 1 open reading frame 105 2.5642
ADAMTSL4-AS2 ADAMTSL4 antisense RNA 2 2.5642
TEX50 testis expressed 50 2.5642
SERPINB2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 2.5642
EVI2A ecotropic viral integration site 2A 2.5642
GOLGA8M golgin A8 family, member M 2.5642
EIF4E1B eukaryotic translation initiation factor 4E family member 1B 2.5642
NKX6-1 NK6 homeobox 1 2.5642
OR13G1 olfactory receptor, family 13, subfamily G, member 1 2.5642
TMDD1 transmembrane and death domain 1 2.5642
SAMD5 sterile alpha motif domain containing 5 2.5642
C17ORF114 chromosome 17 open reading frame 114 2.5642
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 2.5642
GADD45B growth arrest and DNA-damage-inducible, beta 2.5642
MAGED4B melanoma antigen family D4B 2.5642
NTN5 netrin 5 2.5642
PENK proenkephalin 2.5642
CST7 cystatin F (leukocystatin) 2.5642
ZFP57 ZFP57 zinc finger protein 2.5642
PRSS55 protease, serine, 55 2.5642
GARIN1A golgi associated RAB2 interactor 1A 2.5642
DMBT1 deleted in malignant brain tumors 1 2.5642
C3ORF49 chromosome 3 open reading frame 49 2.5642
ACKR2 atypical chemokine receptor 2 2.5642
EPX eosinophil peroxidase 2.5642
LST1 leukocyte specific transcript 1 2.5642
ACTR3C ARP3 actin-related protein 3 homolog C (yeast) 2.5642
MMP3 matrix metallopeptidase 3 2.5642
CCDC190 coiled-coil domain containing 190 2.5642
LRRC74A leucine rich repeat containing 74A 2.5642
BNIP5 BCL2 interacting protein 5 2.5642
RTL9 retrotransposon Gag like 9 2.5642
TGM1 transglutaminase 1 2.5642
TGM3 transglutaminase 3 2.5642
R3HDML R3H domain containing-like 2.5642
PLAAT2 phospholipase A and acyltransferase 2 2.5642
DEFB131B defensin beta 131B 2.5642
GBA3 glucosidase, beta, acid 3 (gene/pseudogene) 2.5642
TP53AIP1 tumor protein p53 regulated apoptosis inducing protein 1 2.5642
VAX2 ventral anterior homeobox 2 2.5642
PCDHGB5 protocadherin gamma subfamily B, 5 2.5642
IL17REL interleukin 17 receptor E-like 2.5642
POU6F1 POU class 6 homeobox 1 2.5642
MEIOSIN meiosis initiator 2.5642
LRRC32 leucine rich repeat containing 32 2.5642
MYOD1 myogenic differentiation 1 2.5642
MYF6 myogenic factor 6 (herculin) 2.5642
DYTN dystrotelin 2.5642
CFAP276 cilia and flagella associated protein 276 2.5642
EXTL1 exostosin-like glycosyltransferase 1 2.5642
SELENOV selenoprotein V 2.56186
LRFN5 leucine rich repeat and fibronectin type III domain containing 5 2.5498
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 2.53894
LZTFL1 leucine zipper transcription factor-like 1 2.52937
EEF1E1 eukaryotic translation elongation factor 1 epsilon 1 2.51311
C9ORF72 chromosome 9 open reading frame 72 2.49865
BRPF1 bromodomain and PHD finger containing, 1 2.47398
BTBD18 BTB (POZ) domain containing 18 2.46902
TLR2 toll-like receptor 2 2.46902
RPL32 ribosomal protein L32 2.4398
SRSF2 serine/arginine-rich splicing factor 2 2.43495
EEIG1 estrogen-induced osteoclastogenesis regulator 1 2.43495
CXCL14 chemokine (C-X-C motif) ligand 14 2.4143
MLANA melan-A 2.40355
RBM24 RNA binding motif protein 24 2.40355
ZNF385A zinc finger protein 385A 2.38757
TTC22 tetratricopeptide repeat domain 22 2.36996
BTBD8 BTB (POZ) domain containing 8 2.35341
KCTD5 potassium channel tetramerization domain containing 5 2.35341
CLIP3 CAP-GLY domain containing linker protein 3 2.33715
DENND4B DENN/MADD domain containing 4B 2.33112
MMP26 matrix metallopeptidase 26 2.33112
INTS8 integrator complex subunit 8 2.33048
MLLT1 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 2.32777
RBM46 RNA binding motif protein 46 2.30153
CASP3 caspase 3, apoptosis-related cysteine peptidase 2.27748
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 2.25823
GALNT15 polypeptide N-acetylgalactosaminyltransferase 15 2.23279
MPP1 membrane protein, palmitoylated 1, 55kDa 2.22055
CRYBG1 crystallin beta-gamma domain containing 1 2.19723
CEP63 centrosomal protein 63kDa 2.18181
WDR7 WD repeat domain 7 2.14998
BCL2L2 BCL2-like 2 2.14203
MARK2 MAP/microtubule affinity-regulating kinase 2 2.11949
CLP1 cleavage and polyadenylation factor I subunit 1 2.11949
PCDH11X protocadherin 11 X-linked 2.11837
CENPS centromere protein S 2.11765
TPM2 tropomyosin 2 (beta) 2.11764
CCNI cyclin I 2.11764
WDR70 WD repeat domain 70 2.11764
MDK midkine (neurite growth-promoting factor 2) 2.11764
DNAH6 dynein, axonemal, heavy chain 6 2.11483
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) 2.11064
ZIM3 zinc finger, imprinted 3 2.10512
UPK2 uroplakin 2 2.09832
NMB neuromedin B 2.09784
EED embryonic ectoderm development 2.08943
CAAP1 caspase activity and apoptosis inhibitor 1 2.08722
ROBO2 roundabout, axon guidance receptor, homolog 2 (Drosophila) 2.08113
INTU inturned planar cell polarity protein 2.06588
PDHB pyruvate dehydrogenase (lipoamide) beta 2.06588
ADGRL2 adhesion G protein-coupled receptor L2 2.06449
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3 2.06221
TMEM230 transmembrane protein 230 2.05836
RIMOC1 RAB7A interacting MON1-CCZ1 complex subunit 1 2.05836
PCDH7 protocadherin 7 2.05836
KREMEN2 kringle containing transmembrane protein 2 2.05124
PRMT8 protein arginine methyltransferase 8 2.04285
SDE2 SDE2 telomere maintenance homolog (S. pombe) 2.04285
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 2.02181
TPRKB TP53RK binding protein 2.01914
RBM8A RNA binding motif protein 8A 2.0106

decreased expression

Symbol Name Standardized Value
SYNPR synaptoporin -2.59925
PCSK1 proprotein convertase subtilisin/kexin type 1 -2.57104
CUBN cubilin (intrinsic factor-cobalamin receptor) -2.57104
RTL5 retrotransposon Gag like 5 -2.5642
LYNX1 Ly6/neurotoxin 1 -2.5642
FGFR3 fibroblast growth factor receptor 3 -2.5642
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa -2.5642
FGF4 fibroblast growth factor 4 -2.5642
RNASE1 ribonuclease, RNase A family, 1 (pancreatic) -2.5642
ANPEP alanyl (membrane) aminopeptidase -2.5642
AGPAT4 1-acylglycerol-3-phosphate O-acyltransferase 4 -2.5642
CLCNKB chloride channel, voltage-sensitive Kb -2.5642
LY6G5C lymphocyte antigen 6 complex, locus G5C -2.5642
FOXP3 forkhead box P3 -2.5642
PRAP1 proline-rich acidic protein 1 -2.5642
RERGL RERG/RAS-like -2.5642
SLC22A13 solute carrier family 22 (organic anion/urate transporter), member 13 -2.5642
NME8 NME/NM23 family member 8 -2.5642
DNAI7 dynein axonemal intermediate chain 7 -2.5642
SPRR2F small proline-rich protein 2F -2.5642
LOC124900192 uncharacterized LOC124900192 -2.5642
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3 -2.5642
HTR3E 5-hydroxytryptamine (serotonin) receptor 3E, ionotropic -2.5642
LTB lymphotoxin beta (TNF superfamily, member 3) -2.5642
MMD2 monocyte to macrophage differentiation-associated 2 -2.5642
FCGR2A Fc fragment of IgG, low affinity IIa, receptor (CD32) -2.5642
LOC390937 Ets2 repressor factor-like -2.5642
GJA9 gap junction protein, alpha 9, 59kDa -2.5642
UPK3A uroplakin 3A -2.5642
ADAMTS9 ADAM metallopeptidase with thrombospondin type 1 motif, 9 -2.5642
SLC16A11 solute carrier family 16, member 11 -2.5642
MT1M metallothionein 1M -2.5642
NGFR nerve growth factor receptor -2.5642
UPK1B uroplakin 1B -2.5642
TMEM132D transmembrane protein 132D -2.5642
LRRC4C leucine rich repeat containing 4C -2.5642
DRC1 dynein regulatory complex subunit 1 -2.5642
STAB1 stabilin 1 -2.5642
CDH22 cadherin 22, type 2 -2.5642
CERS3 ceramide synthase 3 -2.5642
CFAP44 cilia and flagella associated protein 44 -2.49756
EBF1 early B-cell factor 1 -2.44249
ENO3 enolase 3 (beta, muscle) -2.43495
WDR1 WD repeat domain 1 -2.43495
COPB2 coatomer protein complex, subunit beta 2 (beta prime) -2.43495
H3C12 H3 clustered histone 12 -2.4143
RCN3 reticulocalbin 3, EF-hand calcium binding domain -2.40726
TNNI3K TNNI3 interacting kinase -2.39161
FZD9 frizzled class receptor 9 -2.39161
ELL3 elongation factor RNA polymerase II-like 3 -2.3722
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1 -2.3722
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) -2.36229
PTGIS prostaglandin I2 (prostacyclin) synthase -2.34596
PRKAG1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit -2.3426
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) -2.30903
SMIM1 small integral membrane protein 1 (Vel blood group) -2.27986
ELL elongation factor RNA polymerase II -2.27763
TMSB15C thymosin beta 15C -2.27763
ASF1A anti-silencing function 1A histone chaperone -2.27763
KNL1 kinetochore scaffold 1 -2.27363
TSPAN14 tetraspanin 14 -2.22002
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 -2.19723
ESRRG estrogen-related receptor gamma -2.19368
ST6GAL1 ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 -2.15624
UBAP1L ubiquitin associated protein 1-like -2.14203
MARCHF9 membrane associated ring-CH-type finger 9 -2.11949
HAVCR2 hepatitis A virus cellular receptor 2 -2.11949
YIPF2 Yip1 domain family, member 2 -2.11949
GON4L gon-4-like (C. elegans) -2.11949
IFNAR2 interferon (alpha, beta and omega) receptor 2 -2.11949
SLC15A3 solute carrier family 15 (oligopeptide transporter), member 3 -2.11483
STARD5 StAR-related lipid transfer (START) domain containing 5 -2.11483
LRRC14 leucine rich repeat containing 14 -2.09667
RASAL2 RAS protein activator like 2 -2.09312
ESRP1 epithelial splicing regulatory protein 1 -2.08943
FRAS1 Fraser extracellular matrix complex subunit 1 -2.08943
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled -2.08943
SYNGR3 synaptogyrin 3 -2.08649
ADCY6 adenylate cyclase 6 -2.08649
GBA1 glucosylceramidase beta 1 -2.08191
NUDT17 nudix (nucleoside diphosphate linked moiety X)-type motif 17 -2.08191
GAS2L1 growth arrest-specific 2 like 1 -2.06436
KAT2A K(lysine) acetyltransferase 2A -2.06221
ZIC3 Zic family member 3 -2.05124
ARHGAP39 Rho GTPase activating protein 39 -2.05124
CNBP CCHC-type zinc finger, nucleic acid binding protein -2.04283
ZFYVE1 zinc finger, FYVE domain containing 1 -2.04097
NUP62 nucleoporin 62kDa -2.0332
TSLIG3C tRNA splicing ligase complex subunit 3C -2.03307
INAFM1 InaF-motif containing 1 -2.03114
FAM91A1 family with sequence similarity 91, member A1 -2.03114
TULP1 tubby like protein 1 -2.02884
CAMK2D calcium/calmodulin-dependent protein kinase II delta -2.02181
ATP9B ATPase, class II, type 9B -2.01914
NOCT nocturnin -2.0106