| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/ESC_J1_UP_LATE.V1_UP |
| Similar Terms | |
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377 genes differentially expressed following the ESC_J1_UP_LATE.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| ABHD5 | abhydrolase domain containing 5 |
| ADAM10 | ADAM metallopeptidase domain 10 |
| AFP | alpha-fetoprotein |
| AMN | amnion associated transmembrane protein |
| AMOT | angiomotin |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) |
| APOA1 | apolipoprotein A-I |
| APOA2 | apolipoprotein A-II |
| APOB | apolipoprotein B |
| APOC2 | apolipoprotein C-II |
| APOM | apolipoprotein M |
| APP | amyloid beta (A4) precursor protein |
| ARAP2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 |
| ATF3 | activating transcription factor 3 |
| B4GALNT2 | beta-1,4-N-acetyl-galactosaminyl transferase 2 |
| BGN | biglycan |
| BICC1 | BicC family RNA binding protein 1 |
| BMP2 | bone morphogenetic protein 2 |
| C1ORF210 | chromosome 1 open reading frame 210 |
| CA4 | carbonic anhydrase IV |
| CAPN6 | calpain 6 |
| CBX4 | chromobox homolog 4 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CHRNB1 | cholinergic receptor, nicotinic, beta 1 (muscle) |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
| CIDEB | cell death-inducing DFFA-like effector b |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 |
| CLDN7 | claudin 7 |
| COL2A1 | collagen, type II, alpha 1 |
| COL4A1 | collagen, type IV, alpha 1 |
| COL4A2 | collagen, type IV, alpha 2 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) |
| CRYAB | crystallin, alpha B |
| CTGF | connective tissue growth factor |
| CTSC | cathepsin C |
| CTSH | cathepsin H |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DAZL | deleted in azoospermia-like |
| DBNDD2 | dysbindin (dystrobrevin binding protein 1) domain containing 2 |
| DLK1 | delta-like 1 homolog (Drosophila) |
| DPP4 | dipeptidyl-peptidase 4 |
| DRAM1 | DNA-damage regulated autophagy modulator 1 |
| DSP | desmoplakin |
| EFNA1 | ephrin-A1 |
| ENPEP | glutamyl aminopeptidase (aminopeptidase A) |
| ENPP5 | ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative) |
| ESX1 | ESX homeobox 1 |
| F3 | coagulation factor III (thromboplastin, tissue factor) |
| FAM134B | family with sequence similarity 134, member B |
| FAM213A | family with sequence similarity 213, member A |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
| FGB | fibrinogen beta chain |
| FGF5 | fibroblast growth factor 5 |
| FHL2 | four and a half LIM domains 2 |
| FLVCR2 | feline leukemia virus subgroup C cellular receptor family, member 2 |
| FOXA2 | forkhead box A2 |
| FOXQ1 | forkhead box Q1 |
| FRZB | frizzled-related protein |
| FST | follistatin |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) |
| FXYD3 | FXYD domain containing ion transport regulator 3 |
| GADD45B | growth arrest and DNA-damage-inducible, beta |
| GATA4 | GATA binding protein 4 |
| GATA6 | GATA binding protein 6 |
| GGTA1P | glycoprotein, alpha-galactosyltransferase 1 pseudogene |
| GKN1 | gastrokine 1 |
| GKN2 | gastrokine 2 |
| GLIPR1 | GLI pathogenesis-related 1 |
| GNG12 | guanine nucleotide binding protein (G protein), gamma 12 |
| GPC3 | glypican 3 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| GPX3 | glutathione peroxidase 3 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
| GSN | gelsolin |
| GYG1 | glycogenin 1 |
| H19 | H19, imprinted maternally expressed transcript (non-protein coding) |
| HKDC1 | hexokinase domain containing 1 |
| HLA-DRB1 | major histocompatibility complex, class II, DR beta 1 |
| HMGA2 | high mobility group AT-hook 2 |
| HNF1B | HNF1 homeobox B |
| HNF4A | hepatocyte nuclear factor 4, alpha |
| HS3ST1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 1 |
| HTRA1 | HtrA serine peptidase 1 |
| ID2 | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein |
| IGF2 | insulin-like growth factor 2 |
| IGFBP4 | insulin-like growth factor binding protein 4 |
| IRS2 | insulin receptor substrate 2 |
| KLB | klotho beta |
| KRT19 | keratin 19, type I |
| KRT7 | keratin 7, type II |
| LAMA1 | laminin, alpha 1 |
| LAMB1 | laminin, beta 1 |
| LGALS2 | lectin, galactoside-binding, soluble, 2 |
| LGMN | legumain |
| LMBRD1 | LMBR1 domain containing 1 |
| LMO7 | LIM domain 7 |
| LOXL2 | lysyl oxidase-like 2 |
| LPAR3 | lysophosphatidic acid receptor 3 |
| LXN | latexin |
| MOGAT2 | monoacylglycerol O-acyltransferase 2 |
| MORC4 | MORC family CW-type zinc finger 4 |
| MTTP | microsomal triglyceride transfer protein |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow |
| MYO5B | myosin VB |
| MYO6 | myosin VI |
| MYO7A | myosin VIIA |
| NAGA | N-acetylgalactosaminidase, alpha- |
| NEU1 | sialidase 1 (lysosomal sialidase) |
| NRK | Nik related kinase |
| OAF | OAF homolog (Drosophila) |
| OCLN | occludin |
| P2RX4 | purinergic receptor P2X, ligand gated ion channel, 4 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PARVA | parvin, alpha |
| PCBD1 | pterin-4 alpha-carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha |
| PCDH1 | protocadherin 1 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide |
| PDIA5 | protein disulfide isomerase family A, member 5 |
| PEG3 | paternally expressed 3 |
| PGA5 | pepsinogen 5, group I (pepsinogen A) |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 |
| PLA2G12B | phospholipase A2, group XIIB |
| PLXNB2 | plexin B2 |
| PODXL | podocalyxin-like |
| PRG1 | p53-responsive gene 1 |
| PRICKLE1 | prickle homolog 1 (Drosophila) |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| PRSS8 | protease, serine, 8 |
| PTH1R | parathyroid hormone 1 receptor |
| PTPN21 | protein tyrosine phosphatase, non-receptor type 21 |
| RAB11FIP5 | RAB11 family interacting protein 5 (class I) |
| RAB33B | RAB33B, member RAS oncogene family |
| RAB6B | RAB6B, member RAS oncogene family |
| RAMP2 | receptor (G protein-coupled) activity modifying protein 2 |
| RBP4 | retinol binding protein 4, plasma |
| RGL3 | ral guanine nucleotide dissociation stimulator-like 3 |
| RHOU | ras homolog family member U |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase |
| RNF130 | ring finger protein 130 |
| S100A1 | S100 calcium binding protein A1 |
| S100G | S100 calcium binding protein G |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
| SEPN1 | selenoprotein N, 1 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 |
| SESN3 | sestrin 3 |
| SGCE | sarcoglycan, epsilon |
| SHROOM3 | shroom family member 3 |
| SLC22A23 | solute carrier family 22, member 23 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
| SLC40A1 | solute carrier family 40 (iron-regulated transporter), member 1 |
| SLCO2A1 | solute carrier organic anion transporter family, member 2A1 |
| SNAI1 | snail family zinc finger 1 |
| SOAT2 | sterol O-acyltransferase 2 |
| SOX17 | SRY (sex determining region Y)-box 17 |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 |
| SPP2 | secreted phosphoprotein 2, 24kDa |
| ST5 | suppression of tumorigenicity 5 |
| TAX1BP3 | Tax1 (human T-cell leukemia virus type I) binding protein 3 |
| TCN2 | transcobalamin II |
| TDRD7 | tudor domain containing 7 |
| TEX101 | testis expressed 101 |
| TEX264 | testis expressed 264 |
| TFEC | transcription factor EC |
| TFF3 | trefoil factor 3 (intestinal) |
| TGFBR3 | transforming growth factor, beta receptor III |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMED3 | transmembrane emp24 protein transport domain containing 3 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TNNT1 | troponin T type 1 (skeletal, slow) |
| TPCN1 | two pore segment channel 1 |
| TTR | transthyretin |
| TUFT1 | tuftelin 1 |
| UGT2B10 | UDP glucuronosyltransferase 2 family, polypeptide B10 |
| UNC5B | unc-5 homolog B (C. elegans) |
| VAMP8 | vesicle-associated membrane protein 8 |
| VIL1 | villin 1 |
| WBSCR27 | Williams Beuren syndrome chromosome region 27 |
| WLS | wntless Wnt ligand secretion mediator |
| ZDHHC9 | zinc finger, DHHC-type containing 9 |
| ZFPM1 | zinc finger protein, FOG family member 1 |
| Symbol | Name |
|---|---|
| ACACB | acetyl-CoA carboxylase beta |
| ACTN3 | actinin, alpha 3 (gene/pseudogene) |
| ADAM23 | ADAM metallopeptidase domain 23 |
| AMH | anti-Mullerian hormone |
| ANGPTL4 | angiopoietin-like 4 |
| ANKRD10 | ankyrin repeat domain 10 |
| AOAH | acyloxyacyl hydrolase (neutrophil) |
| ARMC6 | armadillo repeat containing 6 |
| ATG2A | autophagy related 2A |
| ATPAF2 | ATP synthase mitochondrial F1 complex assembly factor 2 |
| BCL3 | B-cell CLL/lymphoma 3 |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BMS1 | BMS1 ribosome biogenesis factor |
| CALML4 | calmodulin-like 4 |
| CAMKK1 | calcium/calmodulin-dependent protein kinase kinase 1, alpha |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase |
| CD1D | CD1d molecule |
| CIRBP | cold inducible RNA binding protein |
| CLTB | clathrin, light chain B |
| CORO1A | coronin, actin binding protein, 1A |
| CRCP | CGRP receptor component |
| CRMP1 | collapsin response mediator protein 1 |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DBR1 | debranching RNA lariats 1 |
| DDC | dopa decarboxylase (aromatic L-amino acid decarboxylase) |
| DDX27 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 27 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked |
| DDX49 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 49 |
| DHODH | dihydroorotate dehydrogenase (quinone) |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) |
| DLC1 | DLC1 Rho GTPase activating protein |
| DNAJC24 | DnaJ (Hsp40) homolog, subfamily C, member 24 |
| DNASE2 | deoxyribonuclease II, lysosomal |
| DOC2A | double C2-like domains, alpha |
| DPYS | dihydropyrimidinase |
| E2F8 | E2F transcription factor 8 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal |
| EDN1 | endothelin 1 |
| EGR1 | early growth response 1 |
| ENDOG | endonuclease G |
| ERAS | ES cell expressed Ras |
| ERCC6L | excision repair cross-complementation group 6-like |
| ETAA1 | Ewing tumor-associated antigen 1 |
| ETV4 | ets variant 4 |
| EVC | Ellis van Creveld protein |
| EXOSC1 | exosome component 1 |
| FAM129A | family with sequence similarity 129, member A |
| FAM169A | family with sequence similarity 169, member A |
| FGF17 | fibroblast growth factor 17 |
| FGF18 | fibroblast growth factor 18 |
| FOXN4 | forkhead box N4 |
| GAP43 | growth associated protein 43 |
| GBX2 | gastrulation brain homeobox 2 |
| GEMIN2 | gem (nuclear organelle) associated protein 2 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 |
| GLI1 | GLI family zinc finger 1 |
| GLI2 | GLI family zinc finger 2 |
| GNG3 | guanine nucleotide binding protein (G protein), gamma 3 |
| GPATCH4 | G patch domain containing 4 |
| GPX2 | glutathione peroxidase 2 |
| GRASP | GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein |
| GSPT2 | G1 to S phase transition 2 |
| GYS1 | glycogen synthase 1 (muscle) |
| HARS2 | histidyl-tRNA synthetase 2, mitochondrial |
| HCK | HCK proto-oncogene, Src family tyrosine kinase |
| HELB | helicase (DNA) B |
| HMCES | 5-hydroxymethylcytosine (hmC) binding, ES cell-specific |
| HOOK2 | hook microtubule-tethering protein 2 |
| ICAM1 | intercellular adhesion molecule 1 |
| INA | internexin neuronal intermediate filament protein, alpha |
| INTS6 | integrator complex subunit 6 |
| ITGB7 | integrin, beta 7 |
| JAM2 | junctional adhesion molecule 2 |
| KLF4 | Kruppel-like factor 4 (gut) |
| KNOP1 | lysine-rich nucleolar protein 1 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase |
| LMNB2 | lamin B2 |
| MAPK7 | mitogen-activated protein kinase 7 |
| MCF2 | MCF.2 cell line derived transforming sequence |
| MDN1 | MDN1, midasin homolog (yeast) |
| MED11 | mediator complex subunit 11 |
| MMP11 | matrix metallopeptidase 11 |
| MORC1 | MORC family CW-type zinc finger 1 |
| MRAS | muscle RAS oncogene homolog |
| MRPL18 | mitochondrial ribosomal protein L18 |
| MRPL19 | mitochondrial ribosomal protein L19 |
| MSANTD2 | Myb/SANT-like DNA-binding domain containing 2 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 |
| MSRB2 | methionine sulfoxide reductase B2 |
| MTG2 | mitochondrial ribosome-associated GTPase 2 |
| MVK | mevalonate kinase |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| NAA10 | N(alpha)-acetyltransferase 10, NatA catalytic subunit |
| NAPSA | napsin A aspartic peptidase |
| NEFH | neurofilament, heavy polypeptide |
| NGFR | nerve growth factor receptor |
| NIFK | nucleolar protein interacting with the FHA domain of MKI67 |
| NNAT | neuronatin |
| NOBOX | NOBOX oogenesis homeobox |
| NOTUM | notum pectinacetylesterase homolog (Drosophila) |
| NPHS1 | nephrosis 1, congenital, Finnish type (nephrin) |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 |
| NSUN4 | NOP2/Sun domain family, member 4 |
| NTN1 | netrin 1 |
| NXF1 | nuclear RNA export factor 1 |
| PARK2 | parkin RBR E3 ubiquitin protein ligase |
| PASK | PAS domain containing serine/threonine kinase |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PDGFC | platelet derived growth factor C |
| PDSS1 | prenyl (decaprenyl) diphosphate synthase, subunit 1 |
| PHB | prohibitin |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 |
| PIH1D1 | PIH1 domain containing 1 |
| PIK3R4 | phosphoinositide-3-kinase, regulatory subunit 4 |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit |
| POLE | polymerase (DNA directed), epsilon, catalytic subunit |
| POLR3K | polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa |
| PPCS | phosphopantothenoylcysteine synthetase |
| PPIL4 | peptidylprolyl isomerase (cyclophilin)-like 4 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 |
| PRMT6 | protein arginine methyltransferase 6 |
| PSMA8 | proteasome (prosome, macropain) subunit, alpha type, 8 |
| PTCH2 | patched 2 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase |
| PTRF | polymerase I and transcript release factor |
| PUS7 | pseudouridylate synthase 7 (putative) |
| QSER1 | glutamine and serine rich 1 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RASIP1 | Ras interacting protein 1 |
| RIOK2 | RIO kinase 2 |
| RNPC3 | RNA-binding region (RNP1, RRM) containing 3 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RPP40 | ribonuclease P/MRP 40kDa subunit |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RRP8 | ribosomal RNA processing 8, methyltransferase, homolog (yeast) |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| SALL1 | spalt-like transcription factor 1 |
| SFN | stratifin |
| SI | sucrase-isomaltase (alpha-glucosidase) |
| SLC1A5 | solute carrier family 1 (neutral amino acid transporter), member 5 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
| SLC47A1 | solute carrier family 47 (multidrug and toxin extrusion), member 1 |
| SLC4A3 | solute carrier family 4 (anion exchanger), member 3 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SNTB2 | syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2) |
| SOCS2 | suppressor of cytokine signaling 2 |
| SOCS3 | suppressor of cytokine signaling 3 |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| STAT4 | signal transducer and activator of transcription 4 |
| STK4 | serine/threonine kinase 4 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein |
| TAF13 | TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 18kDa |
| TBCE | tubulin folding cofactor E |
| TCEA3 | transcription elongation factor A (SII), 3 |
| TCF15 | transcription factor 15 (basic helix-loop-helix) |
| TDGF1 | teratocarcinoma-derived growth factor 1 |
| TET1 | tet methylcytosine dioxygenase 1 |
| TEX40 | testis expressed 40 |
| TFEB | transcription factor EB |
| TGM1 | transglutaminase 1 |
| TGM3 | transglutaminase 3 |
| TLE4 | transducin-like enhancer of split 4 |
| TMEM121 | transmembrane protein 121 |
| TRAIP | TRAF interacting protein |
| TRH | thyrotropin-releasing hormone |
| TRMT1L | tRNA methyltransferase 1 homolog (S. cerevisiae)-like |
| TRPS1 | trichorhinophalangeal syndrome I |
| TSPAN17 | tetraspanin 17 |
| TTC27 | tetratricopeptide repeat domain 27 |
| TTPA | tocopherol (alpha) transfer protein |
| TUBB2B | tubulin, beta 2B class IIb |
| TUBB3 | tubulin, beta 3 class III |
| UXT | ubiquitously-expressed, prefoldin-like chaperone |
| VEGFC | vascular endothelial growth factor C |
| VPS33B | vacuolar protein sorting 33 homolog B (yeast) |
| WDR75 | WD repeat domain 75 |
| WDR83 | WD repeat domain 83 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) |
| ZCCHC10 | zinc finger, CCHC domain containing 10 |
| ZFP62 | ZFP62 zinc finger protein |
| ZNF423 | zinc finger protein 423 |
| ZNF428 | zinc finger protein 428 |
