| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/ESC_V6.5_UP_EARLY.V1_UP |
| Similar Terms | |
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342 genes differentially expressed following the ESC_V6.5_UP_EARLY.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| ABCC6 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
| ACSS1 | acyl-CoA synthetase short-chain family member 1 |
| ADAMTSL4 | ADAMTS-like 4 |
| AGER | advanced glycosylation end product-specific receptor |
| AIRE | autoimmune regulator |
| ANKRD2 | ankyrin repeat domain 2 (stretch responsive muscle) |
| AQP2 | aquaporin 2 (collecting duct) |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
| ARHGAP27 | Rho GTPase activating protein 27 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARHGEF3 | Rho guanine nucleotide exchange factor (GEF) 3 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| ATP8B2 | ATPase, aminophospholipid transporter, class I, type 8B, member 2 |
| B4GALNT2 | beta-1,4-N-acetyl-galactosaminyl transferase 2 |
| BBX | bobby sox homolog (Drosophila) |
| BMP10 | bone morphogenetic protein 10 |
| C9 | complement component 9 |
| CA4 | carbonic anhydrase IV |
| CACNG3 | calcium channel, voltage-dependent, gamma subunit 3 |
| CBWD1 | COBW domain containing 1 |
| CCDC114 | coiled-coil domain containing 114 |
| CCNK | cyclin K |
| CELSR3 | cadherin, EGF LAG seven-pass G-type receptor 3 |
| CEP131 | centrosomal protein 131kDa |
| CGNL1 | cingulin-like 1 |
| CHD7 | chromodomain helicase DNA binding protein 7 |
| CLEC11A | C-type lectin domain family 11, member A |
| CORT | cortistatin |
| CRAT | carnitine O-acetyltransferase |
| CSN1S2BP | casein alpha s2-like B, pseudogene |
| CSNK1G1 | casein kinase 1, gamma 1 |
| CYP27A1 | cytochrome P450, family 27, subfamily A, polypeptide 1 |
| DACH1 | dachshund family transcription factor 1 |
| DEPTOR | DEP domain containing MTOR-interacting protein |
| DLC1 | DLC1 Rho GTPase activating protein |
| DLL3 | delta-like 3 (Drosophila) |
| DNAJB2 | DnaJ (Hsp40) homolog, subfamily B, member 2 |
| DOC2A | double C2-like domains, alpha |
| DRC1 | dynein regulatory complex subunit 1 |
| ECE1 | endothelin converting enzyme 1 |
| EFNB2 | ephrin-B2 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| ENG | endoglin |
| ENPP2 | ectonucleotide pyrophosphatase/phosphodiesterase 2 |
| EPB41 | erythrocyte membrane protein band 4.1 |
| ERCC2 | excision repair cross-complementation group 2 |
| F13A1 | coagulation factor XIII, A1 polypeptide |
| FAM189B | family with sequence similarity 189, member B |
| FBP1 | fructose-1,6-bisphosphatase 1 |
| FGF19 | fibroblast growth factor 19 |
| FGF5 | fibroblast growth factor 5 |
| FOXQ1 | forkhead box Q1 |
| GABRR2 | gamma-aminobutyric acid (GABA) A receptor, rho 2 |
| GADD45G | growth arrest and DNA-damage-inducible, gamma |
| GATAD2B | GATA zinc finger domain containing 2B |
| GATS | GATS, stromal antigen 3 opposite strand |
| GDPD3 | glycerophosphodiester phosphodiesterase domain containing 3 |
| GPA33 | glycoprotein A33 (transmembrane) |
| GPD1 | glycerol-3-phosphate dehydrogenase 1 (soluble) |
| GPR153 | G protein-coupled receptor 153 |
| GPRC5B | G protein-coupled receptor, class C, group 5, member B |
| GRM8 | glutamate receptor, metabotropic 8 |
| GSTT2 | glutathione S-transferase theta 2 (gene/pseudogene) |
| HDAC11 | histone deacetylase 11 |
| HES6 | hes family bHLH transcription factor 6 |
| HIGD1C | HIG1 hypoxia inducible domain family, member 1C |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 |
| HTRA2 | HtrA serine peptidase 2 |
| IFNA2 | interferon, alpha 2 |
| IGSF8 | immunoglobulin superfamily, member 8 |
| IRX2 | iroquois homeobox 2 |
| ITIH3 | inter-alpha-trypsin inhibitor heavy chain 3 |
| KCNC1 | potassium channel, voltage gated Shaw related subfamily C, member 1 |
| KIF21A | kinesin family member 21A |
| KLC2 | kinesin light chain 2 |
| KLF13 | Kruppel-like factor 13 |
| LEF1 | lymphoid enhancer-binding factor 1 |
| LIMD2 | LIM domain containing 2 |
| LIPF | lipase, gastric |
| LPAR4 | lysophosphatidic acid receptor 4 |
| LPP-AS2 | LPP antisense RNA 2 |
| LRIG1 | leucine-rich repeats and immunoglobulin-like domains 1 |
| LTF | lactotransferrin |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 |
| MARCH9 | membrane-associated ring finger (C3HC4) 9 |
| MAST3 | microtubule associated serine/threonine kinase 3 |
| MBD4 | methyl-CpG binding domain protein 4 |
| MBOAT1 | membrane bound O-acyltransferase domain containing 1 |
| MDFI | MyoD family inhibitor |
| METTL20 | methyltransferase like 20 |
| MGA | MGA, MAX dimerization protein |
| MLLT1 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1 |
| MYB | v-myb avian myeloblastosis viral oncogene homolog |
| NARF | nuclear prelamin A recognition factor |
| NCOA2 | nuclear receptor coactivator 2 |
| NME3 | NME/NM23 nucleoside diphosphate kinase 3 |
| NRL | neural retina leucine zipper |
| OCLN | occludin |
| OPRD1 | opioid receptor, delta 1 |
| OTUD7A | OTU deubiquitinase 7A |
| OTX2 | orthodenticle homeobox 2 |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 |
| PCP4 | Purkinje cell protein 4 |
| PCYT2 | phosphate cytidylyltransferase 2, ethanolamine |
| PDZK1 | PDZ domain containing 1 |
| PHF21A | PHD finger protein 21A |
| PKDREJ | polycystin (PKD) family receptor for egg jelly |
| PMFBP1 | polyamine modulated factor 1 binding protein 1 |
| POU3F1 | POU class 3 homeobox 1 |
| PRICKLE1 | prickle homolog 1 (Drosophila) |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PSMB9 | proteasome (prosome, macropain) subunit, beta type, 9 |
| PTK7 | protein tyrosine kinase 7 (inactive) |
| PTPN23 | protein tyrosine phosphatase, non-receptor type 23 |
| PURB | purine-rich element binding protein B |
| RAI1 | retinoic acid induced 1 |
| RASAL2 | RAS protein activator like 2 |
| RNF123 | ring finger protein 123 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 |
| RUNX1 | runt-related transcription factor 1 |
| RYR3 | ryanodine receptor 3 |
| SASH1 | SAM and SH3 domain containing 1 |
| SATB1 | SATB homeobox 1 |
| SCAP | SREBF chaperone |
| SEPP1 | selenoprotein P, plasma, 1 |
| SGTB | small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta |
| SH3RF1 | SH3 domain containing ring finger 1 |
| SIMC1 | SUMO-interacting motifs containing 1 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 |
| SLC23A1 | solute carrier family 23 (ascorbic acid transporter), member 1 |
| SLC29A4 | solute carrier family 29 (equilibrative nucleoside transporter), member 4 |
| SLC35G3 | solute carrier family 35, member G3 |
| SLC5A11 | solute carrier family 5 (sodium/inositol cotransporter), member 11 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SOX11 | SRY (sex determining region Y)-box 11 |
| SP1 | Sp1 transcription factor |
| SPEF1 | sperm flagellar 1 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SSX2IP | synovial sarcoma, X breakpoint 2 interacting protein |
| STIM1 | stromal interaction molecule 1 |
| SUV39H2 | suppressor of variegation 3-9 homolog 2 (Drosophila) |
| SYT3 | synaptotagmin III |
| SYT8 | synaptotagmin VIII |
| SYTL2 | synaptotagmin-like 2 |
| TCEAL1 | transcription elongation factor A (SII)-like 1 |
| TERT | telomerase reverse transcriptase |
| TEX2 | testis expressed 2 |
| TEX9 | testis expressed 9 |
| TMCO4 | transmembrane and coiled-coil domains 4 |
| TMEM121 | transmembrane protein 121 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) |
| TMEM186 | transmembrane protein 186 |
| TMEM42 | transmembrane protein 42 |
| TNFRSF1B | tumor necrosis factor receptor superfamily, member 1B |
| TNRC6B | trinucleotide repeat containing 6B |
| TTPA | tocopherol (alpha) transfer protein |
| VEGFB | vascular endothelial growth factor B |
| VPS39 | vacuolar protein sorting 39 homolog (S. cerevisiae) |
| WDFY3 | WD repeat and FYVE domain containing 3 |
| WIPF1 | WAS/WASL interacting protein family, member 1 |
| WNT3A | wingless-type MMTV integration site family, member 3A |
| WT1 | Wilms tumor 1 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 |
| ZG16 | zymogen granule protein 16 |
| ZMAT5 | zinc finger, matrin-type 5 |
| ZNF286A | zinc finger protein 286A |
| ZNF322 | zinc finger protein 322 |
| ZNF771 | zinc finger protein 771 |
| ZNF865 | zinc finger protein 865 |
| ZPBP | zona pellucida binding protein |
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ABCA7 | ATP-binding cassette, sub-family A (ABC1), member 7 |
| ACTA1 | actin, alpha 1, skeletal muscle |
| ADAM21 | ADAM metallopeptidase domain 21 |
| AEBP1 | AE binding protein 1 |
| AHNAK | AHNAK nucleoprotein |
| ALCAM | activated leukocyte cell adhesion molecule |
| ALX3 | ALX homeobox 3 |
| ANXA1 | annexin A1 |
| ANXA2 | annexin A2 |
| ANXA3 | annexin A3 |
| ANXA5 | annexin A5 |
| APP | amyloid beta (A4) precursor protein |
| AQP3 | aquaporin 3 (Gill blood group) |
| AXL | AXL receptor tyrosine kinase |
| B2M | beta-2-microglobulin |
| B4GALT7 | xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 |
| BAG5 | BCL2-associated athanogene 5 |
| BCAN | brevican |
| BCL3 | B-cell CLL/lymphoma 3 |
| BGN | biglycan |
| BHLHE40 | basic helix-loop-helix family, member e40 |
| BMP4 | bone morphogenetic protein 4 |
| BTNL10 | butyrophilin-like 10 |
| C16ORF74 | chromosome 16 open reading frame 74 |
| C16ORF89 | chromosome 16 open reading frame 89 |
| C3ORF70 | chromosome 3 open reading frame 70 |
| CACNA1E | calcium channel, voltage-dependent, R type, alpha 1E subunit |
| CADPS | Ca++-dependent secretion activator |
| CALD1 | caldesmon 1 |
| CALML4 | calmodulin-like 4 |
| CAMK4 | calcium/calmodulin-dependent protein kinase IV |
| CAPN2 | calpain 2, (m/II) large subunit |
| CARD14 | caspase recruitment domain family, member 14 |
| CAV1 | caveolin 1, caveolae protein, 22kDa |
| CCDC34 | coiled-coil domain containing 34 |
| CCDC80 | coiled-coil domain containing 80 |
| CD37 | CD37 molecule |
| CD44 | CD44 molecule (Indian blood group) |
| CDC42EP1 | CDC42 effector protein (Rho GTPase binding) 1 |
| CEACAM21 | carcinoembryonic antigen-related cell adhesion molecule 21 |
| CFB | complement factor B |
| CIZ1 | CDKN1A interacting zinc finger protein 1 |
| CMTM7 | CKLF-like MARVEL transmembrane domain containing 7 |
| COL11A1 | collagen, type XI, alpha 1 |
| COL16A1 | collagen, type XVI, alpha 1 |
| COL1A1 | collagen, type I, alpha 1 |
| COL1A2 | collagen, type I, alpha 2 |
| COL3A1 | collagen, type III, alpha 1 |
| COL4A1 | collagen, type IV, alpha 1 |
| COL4A2 | collagen, type IV, alpha 2 |
| CPE | carboxypeptidase E |
| CRY2 | cryptochrome circadian clock 2 |
| CSRP1 | cysteine and glycine-rich protein 1 |
| CTGF | connective tissue growth factor |
| CYR61 | cysteine-rich, angiogenic inducer, 61 |
| DDHD1 | DDHD domain containing 1 |
| DEGS2 | delta(4)-desaturase, sphingolipid 2 |
| DSP | desmoplakin |
| EMP1 | epithelial membrane protein 1 |
| ESRRA | estrogen-related receptor alpha |
| F2RL1 | coagulation factor II (thrombin) receptor-like 1 |
| FAM198B | family with sequence similarity 198, member B |
| FAP | fibroblast activation protein, alpha |
| FBLN2 | fibulin 2 |
| FBXO28 | F-box protein 28 |
| FBXO6 | F-box protein 6 |
| FGF17 | fibroblast growth factor 17 |
| FGF2 | fibroblast growth factor 2 (basic) |
| FHL2 | four and a half LIM domains 2 |
| FZD5 | frizzled class receptor 5 |
| GAP43 | growth associated protein 43 |
| GBP2 | guanylate binding protein 2, interferon-inducible |
| GBX2 | gastrulation brain homeobox 2 |
| GIMAP3P | GTPase, IMAP family member 3 pseudogene |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GJB5 | gap junction protein, beta 5, 31.1kDa |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) |
| GPX2 | glutathione peroxidase 2 |
| GSN | gelsolin |
| GYS1 | glycogen synthase 1 (muscle) |
| HBEGF | heparin-binding EGF-like growth factor |
| HES7 | hes family bHLH transcription factor 7 |
| HTRA1 | HtrA serine peptidase 1 |
| IGF2 | insulin-like growth factor 2 |
| IGFBP3 | insulin-like growth factor binding protein 3 |
| IGFBP7 | insulin-like growth factor binding protein 7 |
| INHBA | inhibin, beta A |
| INHBB | inhibin, beta B |
| JUNB | jun B proto-oncogene |
| KCNA1 | potassium channel, voltage gated shaker related subfamily A, member 1 |
| KIF18A | kinesin family member 18A |
| KIT | v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLK10 | kallikrein-related peptidase 10 |
| KLK11 | kallikrein-related peptidase 11 |
| KRT16 | keratin 16, type I |
| KRT17 | keratin 17, type I |
| KRT18 | keratin 18, type I |
| KRT19 | keratin 19, type I |
| KRT8 | keratin 8, type II |
| KRTAP13-2 | keratin associated protein 13-2 |
| LAMA1 | laminin, alpha 1 |
| LAMC2 | laminin, gamma 2 |
| LBP | lipopolysaccharide binding protein |
| LOX | lysyl oxidase |
| LOXL1 | lysyl oxidase-like 1 |
| LTBP3 | latent transforming growth factor beta binding protein 3 |
| MAPK13 | mitogen-activated protein kinase 13 |
| MGP | matrix Gla protein |
| MOGAT2 | monoacylglycerol O-acyltransferase 2 |
| MRAS | muscle RAS oncogene homolog |
| MYO7B | myosin VIIB |
| NAB2 | NGFI-A binding protein 2 (EGR1 binding protein 2) |
| NID1 | nidogen 1 |
| NTN1 | netrin 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OAF | OAF homolog (Drosophila) |
| PARVA | parvin, alpha |
| PBX1 | pre-B-cell leukemia homeobox 1 |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PKD1L3 | polycystic kidney disease 1-like 3 |
| PLAU | plasminogen activator, urokinase |
| PLCL2 | phospholipase C-like 2 |
| PMP22 | peripheral myelin protein 22 |
| PNRC2 | proline-rich nuclear receptor coactivator 2 |
| PRCC | papillary renal cell carcinoma (translocation-associated) |
| PTRF | polymerase I and transcript release factor |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 |
| S100A4 | S100 calcium binding protein A4 |
| S100A6 | S100 calcium binding protein A6 |
| SCARA3 | scavenger receptor class A, member 3 |
| SDPR | serum deprivation response |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SERPINF1 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 |
| SERPINF2 | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 |
| SFN | stratifin |
| SLC39A1 | solute carrier family 39 (zinc transporter), member 1 |
| SLC41A3 | solute carrier family 41, member 3 |
| SLC5A5 | solute carrier family 5 (sodium/iodide cotransporter), member 5 |
| SLC8A3 | solute carrier family 8 (sodium/calcium exchanger), member 3 |
| SMARCD3 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3 |
| SNTG1 | syntrophin, gamma 1 |
| SOCS3 | suppressor of cytokine signaling 3 |
| SP5 | Sp5 transcription factor |
| SPINK1 | serine peptidase inhibitor, Kazal type 1 |
| STARD8 | StAR-related lipid transfer (START) domain containing 8 |
| SULT1E1 | sulfotransferase family 1E, estrogen-preferring, member 1 |
| T | T, brachyury homolog (mouse) |
| TAGLN | transgelin |
| TAS2R4 | taste receptor, type 2, member 4 |
| TFCP2L1 | transcription factor CP2-like 1 |
| TFEB | transcription factor EB |
| TGFB1I1 | transforming growth factor beta 1 induced transcript 1 |
| TGM1 | transglutaminase 1 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TNC | tenascin C |
| TNFRSF12A | tumor necrosis factor receptor superfamily, member 12A |
| TRIM54 | tripartite motif containing 54 |
| TSHZ2 | teashirt zinc finger homeobox 2 |
| TTYH2 | tweety family member 2 |
| TUBB6 | tubulin, beta 6 class V |
| UBD | ubiquitin D |
| UTS2 | urotensin 2 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| WSB1 | WD repeat and SOCS box containing 1 |
| YES1 | YES proto-oncogene 1, Src family tyrosine kinase |
| ZADH2 | zinc binding alcohol dehydrogenase domain containing 2 |
| ZBTB32 | zinc finger and BTB domain containing 32 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 |
