| Dataset | MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | gene perturbation identified as [gene symbol]_[perturbation or condition] (Molecular Signatures Database) |
| External Link | http://www.broadinstitute.org/gsea/msigdb/cards/ESC_V6.5_UP_LATE.V1_UP |
| Similar Terms | |
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376 genes differentially expressed following the ESC_V6.5_UP_LATE.V1 gene perturbation from the MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations dataset.
| Symbol | Name |
|---|---|
| AFP | alpha-fetoprotein |
| AMOT | angiomotin |
| ANKS1A | ankyrin repeat and sterile alpha motif domain containing 1A |
| APLNR | apelin receptor |
| APOA1 | apolipoprotein A-I |
| APOB | apolipoprotein B |
| APOC2 | apolipoprotein C-II |
| APOM | apolipoprotein M |
| APP | amyloid beta (A4) precursor protein |
| ARF5 | ADP-ribosylation factor 5 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 |
| ARHGEF16 | Rho guanine nucleotide exchange factor (GEF) 16 |
| ARID3B | AT rich interactive domain 3B (BRIGHT-like) |
| BAIAP2L1 | BAI1-associated protein 2-like 1 |
| BBX | bobby sox homolog (Drosophila) |
| BMP2 | bone morphogenetic protein 2 |
| BVES | blood vessel epicardial substance |
| C14ORF37 | chromosome 14 open reading frame 37 |
| CA14 | carbonic anhydrase XIV |
| CA4 | carbonic anhydrase IV |
| CAPN6 | calpain 6 |
| CCNG2 | cyclin G2 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 |
| CITED1 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 |
| CLDND1 | claudin domain containing 1 |
| CMTM8 | CKLF-like MARVEL transmembrane domain containing 8 |
| COL2A1 | collagen, type II, alpha 1 |
| COL4A1 | collagen, type IV, alpha 1 |
| COL4A2 | collagen, type IV, alpha 2 |
| CTDSPL | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like |
| CTSH | cathepsin H |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) |
| CYBA | cytochrome b-245, alpha polypeptide |
| CYP26A1 | cytochrome P450, family 26, subfamily A, polypeptide 1 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) |
| DCXR | dicarbonyl/L-xylulose reductase |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 |
| DPP4 | dipeptidyl-peptidase 4 |
| EFNA1 | ephrin-A1 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 |
| EOMES | eomesodermin |
| EPB41 | erythrocyte membrane protein band 4.1 |
| EVX1 | even-skipped homeobox 1 |
| FAM107B | family with sequence similarity 107, member B |
| FAM134B | family with sequence similarity 134, member B |
| FAM213A | family with sequence similarity 213, member A |
| FARP1 | FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived) |
| FBXL20 | F-box and leucine-rich repeat protein 20 |
| FGB | fibrinogen beta chain |
| FGF5 | fibroblast growth factor 5 |
| FGF8 | fibroblast growth factor 8 (androgen-induced) |
| FGFRL1 | fibroblast growth factor receptor-like 1 |
| FOXA1 | forkhead box A1 |
| FOXA2 | forkhead box A2 |
| FOXQ1 | forkhead box Q1 |
| FRAT2 | frequently rearranged in advanced T-cell lymphomas 2 |
| FRZB | frizzled-related protein |
| FXYD2 | FXYD domain containing ion transport regulator 2 |
| FZD2 | frizzled class receptor 2 |
| FZD8 | frizzled class receptor 8 |
| G6PC3 | glucose 6 phosphatase, catalytic, 3 |
| GAS1 | growth arrest-specific 1 |
| GATA4 | GATA binding protein 4 |
| GATA6 | GATA binding protein 6 |
| GATAD2B | GATA zinc finger domain containing 2B |
| GATS | GATS, stromal antigen 3 opposite strand |
| GPC3 | glypican 3 |
| GPRC5C | G protein-coupled receptor, class C, group 5, member C |
| GPX3 | glutathione peroxidase 3 |
| GRIK5 | glutamate receptor, ionotropic, kainate 5 |
| GRINA | glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) |
| GSC | goosecoid homeobox |
| GYG1 | glycogenin 1 |
| H19 | H19, imprinted maternally expressed transcript (non-protein coding) |
| H1F0 | H1 histone family, member 0 |
| HBE1 | hemoglobin, epsilon 1 |
| HBG2 | hemoglobin, gamma G |
| HBZ | hemoglobin, zeta |
| HEXA | hexosaminidase A (alpha polypeptide) |
| HEY1 | hes-related family bHLH transcription factor with YRPW motif 1 |
| HNF1B | HNF1 homeobox B |
| HPN | hepsin |
| IER5 | immediate early response 5 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 |
| IMPAD1 | inositol monophosphatase domain containing 1 |
| KDELR3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
| KIAA0930 | KIAA0930 |
| KIF21A | kinesin family member 21A |
| KRT7 | keratin 7, type II |
| LCP1 | lymphocyte cytosolic protein 1 (L-plastin) |
| LGMN | legumain |
| LHX1 | LIM homeobox 1 |
| LIMD2 | LIM domain containing 2 |
| LMBRD1 | LMBR1 domain containing 1 |
| LOXL2 | lysyl oxidase-like 2 |
| LPIN2 | lipin 2 |
| MACROD1 | MACRO domain containing 1 |
| MFAP2 | microfibrillar-associated protein 2 |
| MICU1 | mitochondrial calcium uptake 1 |
| MOGAT2 | monoacylglycerol O-acyltransferase 2 |
| MOSPD1 | motile sperm domain containing 1 |
| MSX2 | msh homeobox 2 |
| MTTP | microsomal triglyceride transfer protein |
| MYL3 | myosin, light chain 3, alkali; ventricular, skeletal, slow |
| MYLIP | myosin regulatory light chain interacting protein |
| MYO6 | myosin VI |
| NAGLU | N-acetylglucosaminidase, alpha |
| NARF | nuclear prelamin A recognition factor |
| NDRG1 | N-myc downstream regulated 1 |
| NENF | neudesin neurotrophic factor |
| NEPNP | nephrocan, pseudogene |
| NRK | Nik related kinase |
| NUDT11 | nudix (nucleoside diphosphate linked moiety X)-type motif 11 |
| OCLN | occludin |
| OPN3 | opsin 3 |
| OTX2 | orthodenticle homeobox 2 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II |
| PARM1 | prostate androgen-regulated mucin-like protein 1 |
| PCMTD2 | protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2 |
| PDLIM3 | PDZ and LIM domain 3 |
| PDZRN3 | PDZ domain containing ring finger 3 |
| PITX2 | paired-like homeodomain 2 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase |
| PKDCC | protein kinase domain containing, cytoplasmic |
| PLAGL1 | pleiomorphic adenoma gene-like 1 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 |
| PLXNB2 | plexin B2 |
| PODXL | podocalyxin-like |
| POSTN | periostin, osteoblast specific factor |
| PRG1 | p53-responsive gene 1 |
| PRICKLE1 | prickle homolog 1 (Drosophila) |
| PRKACB | protein kinase, cAMP-dependent, catalytic, beta |
| PRSS12 | protease, serine, 12 (neurotrypsin, motopsin) |
| PRSS8 | protease, serine, 8 |
| PTH1R | parathyroid hormone 1 receptor |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) |
| PURG | purine-rich element binding protein G |
| RAI1 | retinoic acid induced 1 |
| RAMP2 | receptor (G protein-coupled) activity modifying protein 2 |
| RASAL2 | RAS protein activator like 2 |
| RBP4 | retinol binding protein 4, plasma |
| RECK | reversion-inducing-cysteine-rich protein with kazal motifs |
| RGL3 | ral guanine nucleotide dissociation stimulator-like 3 |
| RHOU | ras homolog family member U |
| RIPK4 | receptor-interacting serine-threonine kinase 4 |
| RNF128 | ring finger protein 128, E3 ubiquitin protein ligase |
| RNF130 | ring finger protein 130 |
| S100G | S100 calcium binding protein G |
| SAMD8 | sterile alpha motif domain containing 8 |
| SATB1 | SATB homeobox 1 |
| SCCPDH | saccharopine dehydrogenase (putative) |
| SEL1L3 | sel-1 suppressor of lin-12-like 3 (C. elegans) |
| SEPN1 | selenoprotein N, 1 |
| SEPP1 | selenoprotein P, plasma, 1 |
| SGCE | sarcoglycan, epsilon |
| SH3RF1 | SH3 domain containing ring finger 1 |
| SIL1 | SIL1 nucleotide exchange factor |
| SIX5 | SIX homeobox 5 |
| SLC22A23 | solute carrier family 22, member 23 |
| SLC27A3 | solute carrier family 27 (fatty acid transporter), member 3 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 |
| SLIT3 | slit homolog 3 (Drosophila) |
| SMIM14 | small integral membrane protein 14 |
| SMPD2 | sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase) |
| SOAT2 | sterol O-acyltransferase 2 |
| SOX17 | SRY (sex determining region Y)-box 17 |
| SPOCK2 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2 |
| SPP2 | secreted phosphoprotein 2, 24kDa |
| STX2 | syntaxin 2 |
| STX7 | syntaxin 7 |
| TCN2 | transcobalamin II |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 |
| TMEM98 | transmembrane protein 98 |
| TMPRSS2 | transmembrane protease, serine 2 |
| TNNC1 | troponin C type 1 (slow) |
| TNNT2 | troponin T type 2 (cardiac) |
| TRAPPC6A | trafficking protein particle complex 6A |
| TSPAN7 | tetraspanin 7 |
| TTR | transthyretin |
| UNC5B | unc-5 homolog B (C. elegans) |
| VAMP8 | vesicle-associated membrane protein 8 |
| VEGFB | vascular endothelial growth factor B |
| VIL1 | villin 1 |
| WLS | wntless Wnt ligand secretion mediator |
| ZDHHC9 | zinc finger, DHHC-type containing 9 |
| ZFPM1 | zinc finger protein, FOG family member 1 |
| ZNF521 | zinc finger protein 521 |
| Symbol | Name |
|---|---|
| ABCA2 | ATP-binding cassette, sub-family A (ABC1), member 2 |
| ACACB | acetyl-CoA carboxylase beta |
| ACOT8 | acyl-CoA thioesterase 8 |
| ACTN3 | actinin, alpha 3 (gene/pseudogene) |
| ADA | adenosine deaminase |
| ANGPTL4 | angiopoietin-like 4 |
| ANXA1 | annexin A1 |
| AOAH | acyloxyacyl hydrolase (neutrophil) |
| AP4M1 | adaptor-related protein complex 4, mu 1 subunit |
| ARMC6 | armadillo repeat containing 6 |
| ATF1 | activating transcription factor 1 |
| AVPI1 | arginine vasopressin-induced 1 |
| BCL3 | B-cell CLL/lymphoma 3 |
| BDH1 | 3-hydroxybutyrate dehydrogenase, type 1 |
| BGN | biglycan |
| BID | BH3 interacting domain death agonist |
| BIRC6 | baculoviral IAP repeat containing 6 |
| BNIPL | BCL2/adenovirus E1B 19kD interacting protein like |
| BSCL2 | Berardinelli-Seip congenital lipodystrophy 2 (seipin) |
| C11ORF24 | chromosome 11 open reading frame 24 |
| C16ORF74 | chromosome 16 open reading frame 74 |
| C16ORF89 | chromosome 16 open reading frame 89 |
| C17ORF96 | chromosome 17 open reading frame 96 |
| C19ORF48 | chromosome 19 open reading frame 48 |
| CAAP1 | caspase activity and apoptosis inhibitor 1 |
| CALML4 | calmodulin-like 4 |
| CBR3 | carbonyl reductase 3 |
| CBX7 | chromobox homolog 7 |
| CBY1 | chibby homolog 1 (Drosophila) |
| CCNB1IP1 | cyclin B1 interacting protein 1, E3 ubiquitin protein ligase |
| CD38 | CD38 molecule |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 |
| CLTB | clathrin, light chain B |
| CRCP | CGRP receptor component |
| CRMP1 | collapsin response mediator protein 1 |
| CTH | cystathionine gamma-lyase |
| CYCTP | cytochrome c, testis, pseudogene |
| DAPP1 | dual adaptor of phosphotyrosine and 3-phosphoinositides |
| DBR1 | debranching RNA lariats 1 |
| DCLRE1B | DNA cross-link repair 1B |
| DDX4 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 4 |
| DDX51 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 51 |
| DEDD2 | death effector domain containing 2 |
| DIMT1 | DIM1 dimethyladenosine transferase 1 homolog (S. cerevisiae) |
| DPPA2 | developmental pluripotency associated 2 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 |
| E2F8 | E2F transcription factor 8 |
| ECH1 | enoyl CoA hydratase 1, peroxisomal |
| EMP1 | epithelial membrane protein 1 |
| ERAS | ES cell expressed Ras |
| ESRRB | estrogen-related receptor beta |
| ETV4 | ets variant 4 |
| EXOSC1 | exosome component 1 |
| FAM169A | family with sequence similarity 169, member A |
| FAM208B | family with sequence similarity 208, member B |
| FASTKD2 | FAST kinase domains 2 |
| FBLN2 | fibulin 2 |
| FBXO15 | F-box protein 15 |
| FGF17 | fibroblast growth factor 17 |
| FOXD3 | forkhead box D3 |
| FTSJ3 | FtsJ homolog 3 (E. coli) |
| FZD5 | frizzled class receptor 5 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha |
| GBX2 | gastrulation brain homeobox 2 |
| GDF3 | growth differentiation factor 3 |
| GEMIN2 | gem (nuclear organelle) associated protein 2 |
| GGCT | gamma-glutamylcyclotransferase |
| GIMAP3P | GTPase, IMAP family member 3 pseudogene |
| GJB3 | gap junction protein, beta 3, 31kDa |
| GJB5 | gap junction protein, beta 5, 31.1kDa |
| GLI1 | GLI family zinc finger 1 |
| GLI2 | GLI family zinc finger 2 |
| GPA33 | glycoprotein A33 (transmembrane) |
| GPATCH4 | G patch domain containing 4 |
| GPX2 | glutathione peroxidase 2 |
| GYS1 | glycogen synthase 1 (muscle) |
| HADHB | hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit |
| HES7 | hes family bHLH transcription factor 7 |
| HMCES | 5-hydroxymethylcytosine (hmC) binding, ES cell-specific |
| ICAM1 | intercellular adhesion molecule 1 |
| INHBA | inhibin, beta A |
| INHBB | inhibin, beta B |
| ITGB7 | integrin, beta 7 |
| JAM2 | junctional adhesion molecule 2 |
| KAT2B | K(lysine) acetyltransferase 2B |
| KAT6B | K(lysine) acetyltransferase 6B |
| KCNA1 | potassium channel, voltage gated shaker related subfamily A, member 1 |
| KIF18A | kinesin family member 18A |
| KLF4 | Kruppel-like factor 4 (gut) |
| KLK10 | kallikrein-related peptidase 10 |
| KRT17 | keratin 17, type I |
| LCK | LCK proto-oncogene, Src family tyrosine kinase |
| LGALS3 | lectin, galactoside-binding, soluble, 3 |
| LOX | lysyl oxidase |
| MANBA | mannosidase, beta A, lysosomal |
| MDN1 | MDN1, midasin homolog (yeast) |
| MED29 | mediator complex subunit 29 |
| MGP | matrix Gla protein |
| MORC1 | MORC family CW-type zinc finger 1 |
| MPC1 | mitochondrial pyruvate carrier 1 |
| MRAS | muscle RAS oncogene homolog |
| MSC | musculin |
| MSRB2 | methionine sulfoxide reductase B2 |
| MTG2 | mitochondrial ribosome-associated GTPase 2 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog |
| N6AMT2 | N-6 adenine-specific DNA methyltransferase 2 (putative) |
| NEFH | neurofilament, heavy polypeptide |
| NEFL | neurofilament, light polypeptide |
| NOL12 | nucleolar protein 12 |
| NOTUM | notum pectinacetylesterase homolog (Drosophila) |
| NPHS1 | nephrosis 1, congenital, Finnish type (nephrin) |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 |
| NUPR1 | nuclear protein, transcriptional regulator, 1 |
| OLIG2 | oligodendrocyte lineage transcription factor 2 |
| PCOLCE | procollagen C-endopeptidase enhancer |
| PCOLCE2 | procollagen C-endopeptidase enhancer 2 |
| PDE12 | phosphodiesterase 12 |
| PDGFC | platelet derived growth factor C |
| PDSS1 | prenyl (decaprenyl) diphosphate synthase, subunit 1 |
| PHB | prohibitin |
| PLA2G1B | phospholipase A2, group IB (pancreas) |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 |
| PLK3 | polo-like kinase 3 |
| POLA1 | polymerase (DNA directed), alpha 1, catalytic subunit |
| PRADC1 | protease-associated domain containing 1 |
| PRCC | papillary renal cell carcinoma (translocation-associated) |
| PRX | periaxin |
| PSMA8 | proteasome (prosome, macropain) subunit, alpha type, 8 |
| PTCD1 | pentatricopeptide repeat domain 1 |
| PTRF | polymerase I and transcript release factor |
| QTRTD1 | queuine tRNA-ribosyltransferase domain containing 1 |
| RASGRP2 | RAS guanyl releasing protein 2 (calcium and DAG-regulated) |
| RASIP1 | Ras interacting protein 1 |
| RBM43 | RNA binding motif protein 43 |
| RIOK2 | RIO kinase 2 |
| RPP25 | ribonuclease P/MRP 25kDa subunit |
| RRP12 | ribosomal RNA processing 12 homolog (S. cerevisiae) |
| RRP9 | ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast) |
| S100A4 | S100 calcium binding protein A4 |
| S100A6 | S100 calcium binding protein A6 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B |
| SEPT1 | septin 1 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 |
| SFN | stratifin |
| SGK1 | serum/glucocorticoid regulated kinase 1 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 |
| SMPDL3B | sphingomyelin phosphodiesterase, acid-like 3B |
| SOCS3 | suppressor of cytokine signaling 3 |
| SPP1 | secreted phosphoprotein 1 |
| SPRY4 | sprouty homolog 4 (Drosophila) |
| SPTBN4 | spectrin, beta, non-erythrocytic 4 |
| SULT4A1 | sulfotransferase family 4A, member 1 |
| TAF1C | TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa |
| TCEA3 | transcription elongation factor A (SII), 3 |
| TCF15 | transcription factor 15 (basic helix-loop-helix) |
| TEX14 | testis expressed 14 |
| TEX19 | testis expressed 19 |
| TFEB | transcription factor EB |
| TGM1 | transglutaminase 1 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 |
| TLE4 | transducin-like enhancer of split 4 |
| TM4SF1 | transmembrane 4 L six family member 1 |
| TMEM79 | transmembrane protein 79 |
| TRIB3 | tribbles pseudokinase 3 |
| TRMT1L | tRNA methyltransferase 1 homolog (S. cerevisiae)-like |
| TTC39B | tetratricopeptide repeat domain 39B |
| TTYH2 | tweety family member 2 |
| TUBB3 | tubulin, beta 3 class III |
| UFM1 | ubiquitin-fold modifier 1 |
| VAC14 | Vac14 homolog (S. cerevisiae) |
| WDR46 | WD repeat domain 46 |
| WDR75 | WD repeat domain 75 |
| ZBTB21 | zinc finger and BTB domain containing 21 |
| ZBTB32 | zinc finger and BTB domain containing 32 |
| ZBTB45 | zinc finger and BTB domain containing 45 |
| ZBTB8A | zinc finger and BTB domain containing 8A |
| ZC3H8 | zinc finger CCCH-type containing 8 |
| ZCCHC10 | zinc finger, CCHC domain containing 10 |
| ZFP1 | ZFP1 zinc finger protein |
| ZFP42 | ZFP42 zinc finger protein |
| ZFP57 | ZFP57 zinc finger protein |
| ZMYM3 | zinc finger, MYM-type 3 |
| ZNF274 | zinc finger protein 274 |
| ZNF423 | zinc finger protein 423 |
| ZNF428 | zinc finger protein 428 |
| ZNF566 | zinc finger protein 566 |
