ESPL1 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description extra spindle pole bodies homolog 1 (S. cerevisiae)|Stable cohesion between sister chromatids before anaphase and their timely separation during anaphase are critical for chromosome inheritance. In vertebrates, sister chromatid cohesion is released in 2 steps via distinct mechanisms. The first step involves phosphorylation of STAG1 (MIM 604358) or STAG2 (MIM 300826) in the cohesin complex. The second step involves cleavage of the cohesin subunit SCC1 (RAD21; MIM 606462) by ESPL1, or separase, which initiates the final separation of sister chromatids (Sun et al., 2009 [PubMed 19345191]).[supplied by OMIM, Nov 2010] (NCBI Entrez Gene Database, 9700)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_ESPL1
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Genes

88 co-expressed genes for ESPL1 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
AFG3L2 AFG3-like AAA ATPase 2
ASF1B anti-silencing function 1B histone chaperone
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9)
ATP5O ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
AURKB aurora kinase B
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BIRC5 baculoviral IAP repeat containing 5
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
CCNA2 cyclin A2
CCNB2 cyclin B2
CCT5 chaperonin containing TCP1, subunit 5 (epsilon)
CDC20 cell division cycle 20
CDCA8 cell division cycle associated 8
CENPA centromere protein A
CENPE centromere protein E, 312kDa
CENPM centromere protein M
CHERP calcium homeostasis endoplasmic reticulum protein
CKS1B CDC28 protein kinase regulatory subunit 1B
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit
CS citrate synthase
CSNK2B casein kinase 2, beta polypeptide
CYCS cytochrome c, somatic
DDX19B DEAD (Asp-Glu-Ala-Asp) box polypeptide 19B
DNAJC9 DnaJ (Hsp40) homolog, subfamily C, member 9
DNMT1 DNA (cytosine-5-)-methyltransferase 1
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
FEN1 flap structure-specific endonuclease 1
FOXM1 forkhead box M1
FUS FUS RNA binding protein
GLO1 glyoxalase I
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GOT2 glutamic-oxaloacetic transaminase 2, mitochondrial
H2AFZ H2A histone family, member Z
HAT1 histone acetyltransferase 1
HCFC1 host cell factor C1
HMMR hyaluronan-mediated motility receptor (RHAMM)
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1
HNRNPAB heterogeneous nuclear ribonucleoprotein A/B
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
KHSRP KH-type splicing regulatory protein
KIF11 kinesin family member 11
KIF20A kinesin family member 20A
KIF2C kinesin family member 2C
KIFC1 kinesin family member C1
LMNB2 lamin B2
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MCM2 minichromosome maintenance complex component 2
MCM3 minichromosome maintenance complex component 3
MCM4 minichromosome maintenance complex component 4
MCM6 minichromosome maintenance complex component 6
MELK maternal embryonic leucine zipper kinase
MFAP1 microfibrillar-associated protein 1
MKI67 marker of proliferation Ki-67
NCAPD2 non-SMC condensin I complex, subunit D2
NUDC nudC nuclear distribution protein
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PCNA proliferating cell nuclear antigen
PLK1 polo-like kinase 1
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
PPM1G protein phosphatase, Mg2+/Mn2+ dependent, 1G
PPP1CC protein phosphatase 1, catalytic subunit, gamma isozyme
PRPS2 phosphoribosyl pyrophosphate synthetase 2
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PTGES3 prostaglandin E synthase 3 (cytosolic)
RAD23A RAD23 homolog A (S. cerevisiae)
RFC4 replication factor C (activator 1) 4, 37kDa
RRM1 ribonucleotide reductase M1
RRM2 ribonucleotide reductase M2
SMC2 structural maintenance of chromosomes 2
SNRPA small nuclear ribonucleoprotein polypeptide A
SPAG5 sperm associated antigen 5
SSBP1 single-stranded DNA binding protein 1, mitochondrial
SSRP1 structure specific recognition protein 1
TARDBP TAR DNA binding protein
TFDP1 transcription factor Dp-1
TOP2A topoisomerase (DNA) II alpha 170kDa
TPX2 TPX2, microtubule-associated
TRIM28 tripartite motif containing 28
TYMS thymidylate synthetase
UBE2C ubiquitin-conjugating enzyme E2C
VDAC1 voltage-dependent anion channel 1
WHSC1 Wolf-Hirschhorn syndrome candidate 1
YARS tyrosyl-tRNA synthetase
ZWINT ZW10 interacting kinetochore protein