ESR-mediated signaling Gene Set

Dataset Reactome Pathways 2024
Category structural or functional annotations
Type pathway
External Link https://reactome.org/PathwayBrowser/#/R-HSA-8939211
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Genes

189 proteins participating in the ESR-mediated signaling pathway from the Reactome Pathways 2024 dataset.

Symbol Name
AGO1 argonaute RISC catalytic component 1
AGO2 argonaute RISC catalytic component 2
AGO3 argonaute RISC catalytic component 3
AGO4 argonaute RISC catalytic component 4
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
AKT3 v-akt murine thymoma viral oncogene homolog 3
AREG amphiregulin
ATF2 activating transcription factor 2
AXIN1 axin 1
BCL2 B-cell CLL/lymphoma 2
BTC betacellulin
CALM1 calmodulin 1 (phosphorylase kinase, delta)
CARM1 coactivator-associated arginine methyltransferase 1
CAV1 caveolin 1, caveolae protein, 22kDa
CAV2 caveolin 2
CBFB core-binding factor, beta subunit
CCND1 cyclin D1
CCNT1 cyclin T1
CDK9 cyclin-dependent kinase 9
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CHD1 chromodomain helicase DNA binding protein 1
CITED1 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
CREB1 cAMP responsive element binding protein 1
CREBBP CREB binding protein
CTSD cathepsin D
CXCL12 chemokine (C-X-C motif) ligand 12
CXXC5 CXXC finger protein 5
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5
EBAG9 estrogen receptor binding site associated, antigen, 9
EGF epidermal growth factor
EGFR epidermal growth factor receptor
ELK1 ELK1, member of ETS oncogene family
EP300 E1A binding protein p300
EPGN epithelial mitogen
ERBB4 erb-b2 receptor tyrosine kinase 4
EREG epiregulin
ESR1 estrogen receptor 1
ESR2 estrogen receptor 2 (ER beta)
FKBP4 FK506 binding protein 4, 59kDa
FKBP5 FK506 binding protein 5
FOS FBJ murine osteosarcoma viral oncogene homolog
FOSB FBJ murine osteosarcoma viral oncogene homolog B
FOXA1 forkhead box A1
FOXO3 forkhead box O3
GATA3 GATA binding protein 3
GNAI1 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
GNAI2 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
GNAT3 guanine nucleotide binding protein, alpha transducing 3
GNB1 guanine nucleotide binding protein (G protein), beta polypeptide 1
GNB2 guanine nucleotide binding protein (G protein), beta polypeptide 2
GNB3 guanine nucleotide binding protein (G protein), beta polypeptide 3
GNB4 guanine nucleotide binding protein (G protein), beta polypeptide 4
GNB5 guanine nucleotide binding protein (G protein), beta 5
GNG10 guanine nucleotide binding protein (G protein), gamma 10
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GNG12 guanine nucleotide binding protein (G protein), gamma 12
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GNG2 guanine nucleotide binding protein (G protein), gamma 2
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GNG5 guanine nucleotide binding protein (G protein), gamma 5
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNG8 guanine nucleotide binding protein (G protein), gamma 8
GNGT1 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
GNGT2 guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
GPAM glycerol-3-phosphate acyltransferase, mitochondrial
GREB1 growth regulation by estrogen in breast cancer 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2A2 general transcription factor IIA, 2, 12kDa
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa
GTF2F2 general transcription factor IIF, polypeptide 2, 30kDa
H2AB1 H2A.B variant histone 1
H2AC14 H2A clustered histone 14
H2AC18 H2A clustered histone 18
H2AC20 H2A clustered histone 20
H2AC4 H2A clustered histone 4
H2AC6 H2A clustered histone 6
H2AC7 H2A clustered histone 7
H2AJ H2A.J histone
H2AX H2A.X variant histone
H2AZ2 H2A.Z variant histone 2
H2BC1 H2B clustered histone 1
H2BC11 H2B clustered histone 11
H2BC12 H2B clustered histone 12
H2BC12L H2B clustered histone 12 like
H2BC13 H2B clustered histone 13
H2BC14 H2B clustered histone 14
H2BC15 H2B clustered histone 15
H2BC17 H2B clustered histone 17
H2BC21 H2B clustered histone 21
H2BC26 H2B clustered histone 26
H2BC3 H2B clustered histone 3
H2BC4 H2B clustered histone 4
H2BC5 H2B clustered histone 5
H2BC9 H2B clustered histone 9
H3-3A H3.3 histone A
H3C15 H3 clustered histone 15
H3C8 H3 clustered histone 8
H4C1 H4 clustered histone 1
HBEGF heparin-binding EGF-like growth factor
HDAC1 histone deacetylase 1
HRAS Harvey rat sarcoma viral oncogene homolog
HSBP1 heat shock factor binding protein 1
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1
IGF1R insulin-like growth factor 1 receptor
JUN jun proto-oncogene
JUND jun D proto-oncogene
KANK1 KN motif and ankyrin repeat domains 1
KAT2B K(lysine) acetyltransferase 2B
KAT5 K(lysine) acetyltransferase 5
KCTD6 potassium channel tetramerization domain containing 6
KDM1A lysine (K)-specific demethylase 1A
KDM4B lysine (K)-specific demethylase 4B
KPNA2 karyopherin alpha 2 (RAG cohort 1, importin alpha 1)
KRAS Kirsten rat sarcoma viral oncogene homolog
MAPK1 mitogen-activated protein kinase 1
MAPK3 mitogen-activated protein kinase 3
MED1 mediator complex subunit 1
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
MMP7 matrix metallopeptidase 7
MMP9 matrix metallopeptidase 9
MOV10 Mov10 RISC complex RNA helicase
MYB v-myb avian myeloblastosis viral oncogene homolog
MYC v-myc avian myelocytomatosis viral oncogene homolog
NCOA1 nuclear receptor coactivator 1
NCOA2 nuclear receptor coactivator 2
NCOA3 nuclear receptor coactivator 3
NOS3 nitric oxide synthase 3 (endothelial cell)
NR5A2 nuclear receptor subfamily 5, group A, member 2
NRAS neuroblastoma RAS viral (v-ras) oncogene homolog
NRIP1 nuclear receptor interacting protein 1
PDPK1 3-phosphoinositide dependent protein kinase 1
PGR progesterone receptor
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIK3R3 phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
POLR2B polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
POLR2C polymerase (RNA) II (DNA directed) polypeptide C, 33kDa
POLR2D polymerase (RNA) II (DNA directed) polypeptide D
POLR2E polymerase (RNA) II (DNA directed) polypeptide E, 25kDa
POLR2F polymerase (RNA) II (DNA directed) polypeptide F
POLR2G polymerase (RNA) II (DNA directed) polypeptide G
POLR2H polymerase (RNA) II (DNA directed) polypeptide H
POLR2I polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
POLR2J polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POLR2L polymerase (RNA) II (DNA directed) polypeptide L, 7.6kDa
POU2F1 POU class 2 homeobox 1
PPID peptidylprolyl isomerase D
PPP5C protein phosphatase 5, catalytic subunit
PRKCZ protein kinase C, zeta
PRMT1 protein arginine methyltransferase 1
PTGES3 prostaglandin E synthase 3 (cytosolic)
PTK2 protein tyrosine kinase 2
RAD21 RAD21 homolog (S. pombe)
RUNX1 runt-related transcription factor 1
S1PR3 sphingosine-1-phosphate receptor 3
SHC1 SHC (Src homology 2 domain containing) transforming protein 1
SMC1A structural maintenance of chromosomes 1A
SMC3 structural maintenance of chromosomes 3
SP1 Sp1 transcription factor
SPHK1 sphingosine kinase 1
SRC SRC proto-oncogene, non-receptor tyrosine kinase
SRF serum response factor (c-fos serum response element-binding transcription factor)
STAG1 stromal antigen 1
STAG2 stromal antigen 2
STRN striatin, calmodulin binding protein
TBP TATA box binding protein
TFF1 trefoil factor 1
TFF3 trefoil factor 3 (intestinal)
TGFA transforming growth factor, alpha
TLE3 transducin-like enhancer of split 3
TNRC6A trinucleotide repeat containing 6A
TNRC6B trinucleotide repeat containing 6B
TNRC6C trinucleotide repeat containing 6C
UHMK1 U2AF homology motif (UHM) kinase 1
USF1 upstream transcription factor 1
USF2 upstream transcription factor 2, c-fos interacting
XPO1 exportin 1
YY1 YY1 transcription factor
ZDHHC21 zinc finger, DHHC-type containing 21
ZDHHC7 zinc finger, DHHC-type containing 7
ZNF217 zinc finger protein 217