ESR1 Gene Set

Dataset MSigDB Cancer Gene Co-expression Modules
Category transcriptomics
Type co-expressed gene
Description estrogen receptor 1|This gene encodes an estrogen receptor, a ligand-activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative promoter usage and alternative splicing result in dozens of transcript variants, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Mar 2014] (NCBI Entrez Gene Database, 2099)
External Link http://www.broadinstitute.org/gsea/msigdb/cards/MORF_ESR1
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Genes

172 co-expressed genes for ESR1 from the MSigDB Cancer Gene Co-expression Modules dataset.

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ADCY3 adenylate cyclase 3
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary)
AFF2 AF4/FMR2 family, member 2
AMFR autocrine motility factor receptor, E3 ubiquitin protein ligase
AQP5 aquaporin 5
AQP7 aquaporin 7
ARL3 ADP-ribosylation factor-like 3
ATP6V0A2 ATPase, H+ transporting, lysosomal V0 subunit a2
ATRX alpha thalassemia/mental retardation syndrome X-linked
BARX2 BARX homeobox 2
BCL2 B-cell CLL/lymphoma 2
BMP10 bone morphogenetic protein 10
BNIP1 BCL2/adenovirus E1B 19kDa interacting protein 1
BRCA1 breast cancer 1, early onset
BRD1 bromodomain containing 1
C1ORF216 chromosome 1 open reading frame 216
CAMK2G calcium/calmodulin-dependent protein kinase II gamma
CASP10 caspase 10, apoptosis-related cysteine peptidase
CD6 CD6 molecule
CDK13 cyclin-dependent kinase 13
CEP135 centrosomal protein 135kDa
CEP162 centrosomal protein 162kDa
CFH complement factor H
CHD9 chromodomain helicase DNA binding protein 9
CLOCK clock circadian regulator
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CRHR1 corticotropin releasing hormone receptor 1
CRYAA crystallin, alpha A
CTRL chymotrypsin-like
CYP11A1 cytochrome P450, family 11, subfamily A, polypeptide 1
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DAPK2 death-associated protein kinase 2
DGCR9 DiGeorge syndrome critical region gene 9 (non-protein coding)
DNAJC16 DnaJ (Hsp40) homolog, subfamily C, member 16
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
DPT dermatopontin
DTNA dystrobrevin, alpha
ECE2 endothelin converting enzyme 2
ELAVL2 ELAV like neuron-specific RNA binding protein 2
EP400 E1A binding protein p400
ERC1 ELKS/RAB6-interacting/CAST family member 1
ESR1 estrogen receptor 1
ETV3 ets variant 3
FAM189A2 family with sequence similarity 189, member A2
FIG4 FIG4 phosphoinositide 5-phosphatase
FLT1 fms-related tyrosine kinase 1
FNTB farnesyltransferase, CAAX box, beta
FOSL1 FOS-like antigen 1
FRYL FRY-like
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GJB5 gap junction protein, beta 5, 31.1kDa
GLE1 GLE1 RNA export mediator
GNPAT glyceronephosphate O-acyltransferase
GPATCH8 G patch domain containing 8
GPR19 G protein-coupled receptor 19
GRIK5 glutamate receptor, ionotropic, kainate 5
GRIP2 glutamate receptor interacting protein 2
HOXD4 homeobox D4
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled
HTR7 5-hydroxytryptamine (serotonin) receptor 7, adenylate cyclase-coupled
IKBKE inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
IL13 interleukin 13
IL16 interleukin 16
IPCEF1 interaction protein for cytohesin exchange factors 1
IRF2 interferon regulatory factor 2
ITIH4 inter-alpha-trypsin inhibitor heavy chain family, member 4
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
IVL involucrin
JRK Jrk homolog (mouse)
KAT8 K(lysine) acetyltransferase 8
KIAA0195 KIAA0195
KIAA0586 KIAA0586
KLHL18 kelch-like family member 18
KRR1 KRR1, small subunit (SSU) processome component, homolog (yeast)
KRT1 keratin 1, type II
KRT2 keratin 2, type II
KRT33A keratin 33A, type I
KRT86 keratin 86, type II
LOC166994 integral membrane glycoprotein-like
LPGAT1 lysophosphatidylglycerol acyltransferase 1
LRRC48 leucine rich repeat containing 48
LTBP4 latent transforming growth factor beta binding protein 4
MAGEA9 melanoma antigen family A9
MC2R melanocortin 2 receptor (adrenocorticotropic hormone)
MC5R melanocortin 5 receptor
MFN1 mitofusin 1
MGA MGA, MAX dimerization protein
MLN motilin
MPP2 membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
MSH3 mutS homolog 3
MSL3 male-specific lethal 3 homolog (Drosophila)
MSX1 msh homeobox 1
MT4 metallothionein 4
MYC v-myc avian myelocytomatosis viral oncogene homolog
MYO9B myosin IXB
NCKIPSD NCK interacting protein with SH3 domain
NF1 neurofibromin 1
NFX1 nuclear transcription factor, X-box binding 1
NOS2 nitric oxide synthase 2, inducible
NPFF neuropeptide FF-amide peptide precursor
NR1I2 nuclear receptor subfamily 1, group I, member 2
NRTN neurturin
NTNG2 netrin G2
NXPE3 neurexophilin and PC-esterase domain family, member 3
P2RY10 purinergic receptor P2Y, G-protein coupled, 10
PAX7 paired box 7
PAX8 paired box 8
PAX9 paired box 9
PAXIP1 PAX interacting (with transcription-activation domain) protein 1
PCF11 PCF11 cleavage and polyadenylation factor subunit
PHF10 PHD finger protein 10
PIAS2 protein inhibitor of activated STAT, 2
PIGB phosphatidylinositol glycan anchor biosynthesis, class B
PIGR polymeric immunoglobulin receptor
PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
POLR2K polymerase (RNA) II (DNA directed) polypeptide K, 7.0kDa
POU6F1 POU class 6 homeobox 1
PPP1R3D protein phosphatase 1, regulatory subunit 3D
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PRSS16 protease, serine, 16 (thymus)
PSG1 pregnancy specific beta-1-glycoprotein 1
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
PVR poliovirus receptor
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBBP8 retinoblastoma binding protein 8
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2
RUNX1 runt-related transcription factor 1
RXRG retinoid X receptor, gamma
SCAMP1 secretory carrier membrane protein 1
SCAPER S-phase cyclin A-associated protein in the ER
SIX3 SIX homeobox 3
SLC13A2 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
SLC16A5 solute carrier family 16 (monocarboxylate transporter), member 5
SLC22A24 solute carrier family 22, member 24
SLC22A6 solute carrier family 22 (organic anion transporter), member 6
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC6A11 solute carrier family 6 (neurotransmitter transporter), member 11
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SSTR5 somatostatin receptor 5
STK17A serine/threonine kinase 17a
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SULT4A1 sulfotransferase family 4A, member 1
SYT5 synaptotagmin V
TACC2 transforming, acidic coiled-coil containing protein 2
TAF2 TAF2 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 150kDa
TBC1D22A TBC1 domain family, member 22A
TBX19 T-box 19
TBX5 T-box 5
TFDP2 transcription factor Dp-2 (E2F dimerization partner 2)
TMEM11 transmembrane protein 11
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TRIM24 tripartite motif containing 24
TTI1 TELO2 interacting protein 1
UBE4B ubiquitination factor E4B
UTRN utrophin
WT1 Wilms tumor 1
ZBTB22 zinc finger and BTB domain containing 22
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF133 zinc finger protein 133
ZNF134 zinc finger protein 134
ZNF157 zinc finger protein 157
ZNF500 zinc finger protein 500
ZNF592 zinc finger protein 592
ZNF710 zinc finger protein 710