ESR2 Gene Set

Dataset JASPAR Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description estrogen receptor 2 (ER beta)|This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2100)
External Link http://www.ncbi.nlm.nih.gov/gene/2100
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Genes

80 target genes of the ESR2 transcription factor predicted using known transcription factor binding site motifs from the JASPAR Predicted Transcription Factor Targets dataset.

Symbol Name
ARHGAP23 Rho GTPase activating protein 23
ATP6V1G2-DDX39B ATP6V1G2-DDX39B readthrough (NMD candidate)
BRAP BRCA1 associated protein
BRD2 bromodomain containing 2
C2ORF88 chromosome 2 open reading frame 88
CCDC115 coiled-coil domain containing 115
CCL22 chemokine (C-C motif) ligand 22
CENPT centromere protein T
CRHBP corticotropin releasing hormone binding protein
CYP21A2 cytochrome P450, family 21, subfamily A, polypeptide 2
DDR1 discoidin domain receptor tyrosine kinase 1
DDX39B DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B
EDN2 endothelin 2
EHMT2 euchromatic histone-lysine N-methyltransferase 2
EIF1AD eukaryotic translation initiation factor 1A domain containing
EIF5A eukaryotic translation initiation factor 5A
FAM101B family with sequence similarity 101, member B
FAM195B family with sequence similarity 195, member B
FAM21A family with sequence similarity 21, member A
FCGR1B Fc fragment of IgG, high affinity Ib, receptor (CD64)
FLOT1 flotillin 1
GNL1 guanine nucleotide binding protein-like 1
GPHRB golgi pH regulator B
GPR162 G protein-coupled receptor 162
GTPBP6 GTP binding protein 6 (putative)
HCG26 HLA complex group 26 (non-protein coding)
HCP5 HLA complex P5 (non-protein coding)
HJURP Holliday junction recognition protein
HLA-E major histocompatibility complex, class I, E
HOXA10 homeobox A10
IMP4 IMP4, U3 small nucleolar ribonucleoprotein
INSR insulin receptor
ITSN2 intersectin 2
KRT35 keratin 35, type I
KRT86 keratin 86, type II
LIMS1 LIM and senescent cell antigen-like domains 1
LINC00685 long intergenic non-protein coding RNA 685
LOC401242 uncharacterized LOC401242
LSM2 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MECR mitochondrial trans-2-enoyl-CoA reductase
MILR1 mast cell immunoglobulin-like receptor 1
MIR3648-1 microRNA 3648-1
MIR3687-1 microRNA 3687-1
MRPL28 mitochondrial ribosomal protein L28
NBPF14 neuroblastoma breakpoint family, member 14
NEU1 sialidase 1 (lysosomal sialidase)
NPEPL1 aminopeptidase-like 1
OVGP1 oviductal glycoprotein 1, 120kDa
PKN1 protein kinase N1
PRH1 proline-rich protein HaeIII subfamily 1
PRL prolactin
PRRC2A proline-rich coiled-coil 2A
PTGES2 prostaglandin E synthase 2
REXO1L1P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1, pseudogene
REXO1L2P REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 2, pseudogene
RNF39 ring finger protein 39
RWDD3 RWD domain containing 3
SH3BP5L SH3-binding domain protein 5-like
SH3KBP1 SH3-domain kinase binding protein 1
SLC25A18 solute carrier family 25 (glutamate carrier), member 18
SLC25A26 solute carrier family 25 (S-adenosylmethionine carrier), member 26
SNX22 sorting nexin 22
SPSB3 splA/ryanodine receptor domain and SOCS box containing 3
SSTR2 somatostatin receptor 2
TCF19 transcription factor 19
TMCO1 transmembrane and coiled-coil domains 1
TMEM99 transmembrane protein 99
TNF tumor necrosis factor
TNXB tenascin XB
TRIM26 tripartite motif containing 26
TRIM40 tripartite motif containing 40
TSPAN2 tetraspanin 2
UFSP1 UFM1-specific peptidase 1 (non-functional)
VARS valyl-tRNA synthetase
VDAC2 voltage-dependent anion channel 2
WNT16 wingless-type MMTV integration site family, member 16
ZFP57 ZFP57 zinc finger protein
ZNF780B zinc finger protein 780B
ZSCAN20 zinc finger and SCAN domain containing 20
ZSCAN31 zinc finger and SCAN domain containing 31