ESR2 Gene Set

Dataset MotifMap Predicted Transcription Factor Targets
Category genomics
Type transcription factor
Description estrogen receptor 2 (ER beta)|This gene encodes a member of the family of estrogen receptors and superfamily of nuclear receptor transcription factors. The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus, cytoplasm, and mitochondria. Upon binding to 17beta-estradiol or related ligands, the encoded protein forms homo- or hetero-dimers that interact with specific DNA sequences to activate transcription. Some isoforms dominantly inhibit the activity of other estrogen receptor family members. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been fully characterized. [provided by RefSeq, Jul 2008] (NCBI Entrez Gene Database, 2100)
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Genes

36 target genes of the ESR2 transcription factor predicted using known transcription factor binding site motifs from the MotifMap Predicted Transcription Factor Targets dataset.

Symbol Name
BICC1 BicC family RNA binding protein 1
CAV1 caveolin 1, caveolae protein, 22kDa
CCRL2 chemokine (C-C motif) receptor-like 2
CHD9 chromodomain helicase DNA binding protein 9
CISH cytokine inducible SH2-containing protein
CLEC11A C-type lectin domain family 11, member A
CRYZ crystallin, zeta (quinone reductase)
DENND3 DENN/MADD domain containing 3
ETNK2 ethanolamine kinase 2
FKBP4 FK506 binding protein 4, 59kDa
GAPDH glyceraldehyde-3-phosphate dehydrogenase
GPR3 G protein-coupled receptor 3
GREB1 growth regulation by estrogen in breast cancer 1
ITGA5 integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
KAT6B K(lysine) acetyltransferase 6B
LGALS2 lectin, galactoside-binding, soluble, 2
LOC642366 uncharacterized LOC642366
LPL lipoprotein lipase
MAP2K7 mitogen-activated protein kinase kinase 7
MINOS1 mitochondrial inner membrane organizing system 1
MINOS1-NBL1 MINOS1-NBL1 readthrough
MROH7 maestro heat-like repeat family member 7
MRPS18A mitochondrial ribosomal protein S18A
MYRF myelin regulatory factor
PHACTR1 phosphatase and actin regulator 1
PIANP PILR alpha associated neural protein
PPARA peroxisome proliferator-activated receptor alpha
PPM1N protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
RAI1 retinoic acid induced 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SLC2A8 solute carrier family 2 (facilitated glucose transporter), member 8
TMED9 transmembrane emp24 protein transport domain containing 9
TMEM213 transmembrane protein 213
UBE2R2 ubiquitin-conjugating enzyme E2R 2
ZNF385A zinc finger protein 385A