| Dataset | LINCS L1000 CMAP CRISPR Knockout Consensus Signatures |
| Category | transcriptomics |
| Type | gene perturbation |
| Description | estrogen-related receptor gamma|This gene encodes a member of the estrogen receptor-related receptor (ESRR) family, which belongs to the nuclear hormone receptor superfamily. All members of the ESRR family share an almost identical DNA binding domain, which is composed of two C4-type zinc finger motifs. The ESRR members are orphan nuclear receptors; they bind to the estrogen response element and steroidogenic factor 1 response element, and activate genes controlled by both response elements in the absence of any ligands. The ESRR family is closely related to the estrogen receptor (ER) family. They share target genes, co-regulators and promoters, and by targeting the same set of genes, the ESRRs seem to interfere with the ER-mediated estrogen response in various ways. It has been reported that the family member encoded by this gene functions as a transcriptional activator of DNA cytosine-5-methyltransferases 1 (Dnmt1) expression by direct binding to its response elements in the DNMT1 promoters, modulates cell proliferation and estrogen signaling in breast cancer, and negatively regulates bone morphogenetic protein 2-induced osteoblast differentiation and bone formation. Multiple alternatively spliced transcript variants have been identified, which mainly differ at the 5' end and some of which encode protein isoforms differing in the N-terminal region. [provided by RefSeq, Aug 2011] (NCBI Entrez Gene Database, 2104) |
| External Link | https://ncbi.nlm.nih.gov/gene/2104 |
| Similar Terms | |
| Downloads & Tools |
499 genes differentially expressed following the ESRRG gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MAP7 | microtubule-associated protein 7 | 0.0269369 |
| TNNT1 | troponin T type 1 (skeletal, slow) | 0.0194272 |
| HSPB1 | heat shock 27kDa protein 1 | 0.0158171 |
| SCGB2A1 | secretoglobin, family 2A, member 1 | 0.0146283 |
| METRN | meteorin, glial cell differentiation regulator | 0.0139476 |
| ECM1 | extracellular matrix protein 1 | 0.01342 |
| RTN2 | reticulon 2 | 0.0129188 |
| NNMT | nicotinamide N-methyltransferase | 0.0127375 |
| ADIRF | adipogenesis regulatory factor | 0.0124191 |
| LCN2 | lipocalin 2 | 0.0122318 |
| AK1 | adenylate kinase 1 | 0.012099 |
| MSLN | mesothelin | 0.0111797 |
| RND3 | Rho family GTPase 3 | 0.0111475 |
| GREM1 | gremlin 1, DAN family BMP antagonist | 0.0111014 |
| SLPI | secretory leukocyte peptidase inhibitor | 0.0108508 |
| SGK1 | serum/glucocorticoid regulated kinase 1 | 0.0106729 |
| BLNK | B-cell linker | 0.0105788 |
| AMOTL2 | angiomotin like 2 | 0.0103741 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0102396 |
| CA2 | carbonic anhydrase II | 0.0101111 |
| KLK10 | kallikrein-related peptidase 10 | 0.0100241 |
| SLC38A1 | solute carrier family 38, member 1 | 0.00999535 |
| MMP1 | matrix metallopeptidase 1 | 0.00981635 |
| CTSD | cathepsin D | 0.00971707 |
| BGN | biglycan | 0.00969871 |
| EIF5A | eukaryotic translation initiation factor 5A | 0.00960047 |
| HSPB8 | heat shock 22kDa protein 8 | 0.00952641 |
| HTRA1 | HtrA serine peptidase 1 | 0.00942984 |
| CLU | clusterin | 0.00941973 |
| NOTCH1 | notch 1 | 0.00935251 |
| MGLL | monoglyceride lipase | 0.00931031 |
| TPPP3 | tubulin polymerization-promoting protein family member 3 | 0.00913278 |
| LSM5 | LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae) | 0.00907775 |
| CLC | Charcot-Leyden crystal galectin | 0.00907501 |
| CCNA2 | cyclin A2 | 0.00906704 |
| LXN | latexin | 0.00904766 |
| GADD45A | growth arrest and DNA-damage-inducible, alpha | 0.00901151 |
| PCLAF | PCNA clamp associated factor | 0.00894868 |
| CXCL12 | chemokine (C-X-C motif) ligand 12 | 0.00894772 |
| CLDN3 | claudin 3 | 0.00883444 |
| WWC1 | WW and C2 domain containing 1 | 0.00861149 |
| EEF1A2 | eukaryotic translation elongation factor 1 alpha 2 | 0.0084777 |
| CCN2 | cellular communication network factor 2 | 0.0084073 |
| POLR2I | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa | 0.00839179 |
| BIN1 | bridging integrator 1 | 0.00839105 |
| NT5E | 5'-nucleotidase, ecto (CD73) | 0.00830314 |
| CLIC5 | chloride intracellular channel 5 | 0.00824357 |
| XIC | X chromosome inactivation center | 0.00822076 |
| S100P | S100 calcium binding protein P | 0.00820923 |
| CRYAB | crystallin, alpha B | 0.00820239 |
| DYNLL1 | dynein, light chain, LC8-type 1 | 0.0081414 |
| LAMP5 | lysosomal-associated membrane protein family, member 5 | 0.00801634 |
| HBD | hemoglobin, delta | 0.00792174 |
| INHBA | inhibin, beta A | 0.00787242 |
| CAPN1 | calpain 1, (mu/I) large subunit | 0.00787058 |
| FOLR1 | folate receptor 1 (adult) | 0.00785593 |
| BMP4 | bone morphogenetic protein 4 | 0.00780047 |
| TSPO | translocator protein (18kDa) | 0.00777869 |
| S100A8 | S100 calcium binding protein A8 | 0.00774762 |
| GAS1 | growth arrest-specific 1 | 0.00772389 |
| COL10A1 | collagen, type X, alpha 1 | 0.00771127 |
| TNNC1 | troponin C type 1 (slow) | 0.00770681 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.00767646 |
| ISYNA1 | inositol-3-phosphate synthase 1 | 0.00766558 |
| GPX3 | glutathione peroxidase 3 | 0.00762128 |
| CRISP3 | cysteine-rich secretory protein 3 | 0.00759883 |
| DOCK9 | dedicator of cytokinesis 9 | 0.00759027 |
| SPINT1 | serine peptidase inhibitor, Kunitz type 1 | 0.00757802 |
| PTK2B | protein tyrosine kinase 2 beta | 0.00756918 |
| TOB1 | transducer of ERBB2, 1 | 0.00756526 |
| EXPH5 | exophilin 5 | 0.00754866 |
| FBLN5 | fibulin 5 | 0.0074895 |
| NEAT1 | nuclear paraspeckle assembly transcript 1 (non-protein coding) | 0.00744254 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.00743003 |
| MMP9 | matrix metallopeptidase 9 | 0.00741836 |
| S100A4 | S100 calcium binding protein A4 | 0.00736883 |
| PHACTR2 | phosphatase and actin regulator 2 | 0.00736408 |
| RRAGD | Ras-related GTP binding D | 0.00735541 |
| MFAP5 | microfibrillar associated protein 5 | 0.00734764 |
| EPS8L1 | EPS8-like 1 | 0.00734088 |
| SUPV3L1 | suppressor of var1, 3-like 1 (S. cerevisiae) | 0.00733333 |
| ELANE | elastase, neutrophil expressed | 0.00732368 |
| TSPAN1 | tetraspanin 1 | 0.00726041 |
| MB | myoglobin | 0.00722874 |
| CHI3L1 | chitinase 3-like 1 (cartilage glycoprotein-39) | 0.00721616 |
| GUCY1A3 | guanylate cyclase 1, soluble, alpha 3 | 0.00720802 |
| QPRT | quinolinate phosphoribosyltransferase | 0.00720154 |
| CRABP2 | cellular retinoic acid binding protein 2 | 0.00718387 |
| CILP | cartilage intermediate layer protein, nucleotide pyrophosphohydrolase | 0.00718018 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.00710409 |
| CAMP | cathelicidin antimicrobial peptide | 0.00709811 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.00709713 |
| AOC1 | amine oxidase, copper containing 1 | 0.00705916 |
| SMC1A | structural maintenance of chromosomes 1A | 0.00705527 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.00697327 |
| FILIP1L | filamin A interacting protein 1-like | 0.00696572 |
| DNAJA3 | DnaJ (Hsp40) homolog, subfamily A, member 3 | 0.00696017 |
| H1-2 | H1.2 linker histone, cluster member | 0.00695296 |
| SLC39A8 | solute carrier family 39 (zinc transporter), member 8 | 0.00695171 |
| RFTN1 | raftlin, lipid raft linker 1 | 0.00690093 |
| ANGPT1 | angiopoietin 1 | 0.0068967 |
| RARRES2 | retinoic acid receptor responder (tazarotene induced) 2 | 0.00689125 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0068855 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.00687481 |
| TFRC | transferrin receptor | 0.0068746 |
| GAS6 | growth arrest-specific 6 | 0.00686727 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.00686476 |
| PLAAT3 | phospholipase A and acyltransferase 3 | 0.00682389 |
| MYLPF | myosin light chain, phosphorylatable, fast skeletal muscle | 0.00682233 |
| CUEDC1 | CUE domain containing 1 | 0.00679699 |
| IDH2 | isocitrate dehydrogenase 2 (NADP+), mitochondrial | 0.0067955 |
| EDN1 | endothelin 1 | 0.00679255 |
| AREG | amphiregulin | 0.00676235 |
| SFRP4 | secreted frizzled-related protein 4 | 0.00675788 |
| CA12 | carbonic anhydrase XII | 0.00673992 |
| TNNI1 | troponin I type 1 (skeletal, slow) | 0.00671326 |
| TPD52L1 | tumor protein D52-like 1 | 0.00670522 |
| IER5 | immediate early response 5 | 0.00668331 |
| PERP | PERP, TP53 apoptosis effector | 0.00667511 |
| P2RX5 | purinergic receptor P2X, ligand gated ion channel, 5 | 0.00665658 |
| SERPING1 | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1 | 0.00665583 |
| PDGFRA | platelet-derived growth factor receptor, alpha polypeptide | 0.00660742 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.00659639 |
| PLK1 | polo-like kinase 1 | 0.00659358 |
| THBS2 | thrombospondin 2 | 0.00657895 |
| KLF6 | Kruppel-like factor 6 | 0.00657387 |
| CHP1 | calcineurin-like EF-hand protein 1 | 0.0065283 |
| SEPTIN11 | septin 11 | 0.00649357 |
| VNN1 | vanin 1 | 0.00647369 |
| TAGLN | transgelin | 0.00645453 |
| C9ORF3 | chromosome 9 open reading frame 3 | 0.00643723 |
| TNNI2 | troponin I type 2 (skeletal, fast) | 0.00641038 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | 0.0064078 |
| ECHDC3 | enoyl CoA hydratase domain containing 3 | 0.0063954 |
| CYP2J2 | cytochrome P450, family 2, subfamily J, polypeptide 2 | 0.00638875 |
| CGA | glycoprotein hormones, alpha polypeptide | 0.00637121 |
| TSPAN12 | tetraspanin 12 | 0.00636235 |
| PPP1R14B | protein phosphatase 1, regulatory (inhibitor) subunit 14B | 0.0063312 |
| TYMS | thymidylate synthetase | 0.00632674 |
| SLC31A2 | solute carrier family 31 (copper transporter), member 2 | 0.00631818 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.00631652 |
| RAP1GAP2 | RAP1 GTPase activating protein 2 | 0.00631647 |
| FZD2 | frizzled class receptor 2 | 0.00631138 |
| SDC1 | syndecan 1 | 0.0063089 |
| CLEC11A | C-type lectin domain family 11, member A | 0.00628617 |
| CKM | creatine kinase, muscle | 0.00627171 |
| ACTN1 | actinin, alpha 1 | 0.00625264 |
| SLC4A2 | solute carrier family 4 (anion exchanger), member 2 | 0.00625105 |
| KLF9 | Kruppel-like factor 9 | 0.0062235 |
| PAPSS2 | 3'-phosphoadenosine 5'-phosphosulfate synthase 2 | 0.00621516 |
| NXN | nucleoredoxin | 0.00620424 |
| ATP2A3 | ATPase, Ca++ transporting, ubiquitous | 0.00620172 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.00618567 |
| NCOA3 | nuclear receptor coactivator 3 | 0.00617791 |
| PCOLCE | procollagen C-endopeptidase enhancer | 0.00616738 |
| KCNK5 | potassium channel, two pore domain subfamily K, member 5 | 0.00614106 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.00614075 |
| RAPGEF5 | Rap guanine nucleotide exchange factor (GEF) 5 | 0.00613621 |
| PLEKHM1 | pleckstrin homology domain containing, family M (with RUN domain) member 1 | 0.00609538 |
| NDUFA4L2 | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2 | 0.00608412 |
| KLK6 | kallikrein-related peptidase 6 | 0.00608176 |
| PLPP2 | phospholipid phosphatase 2 | 0.00606534 |
| HIP1 | huntingtin interacting protein 1 | 0.00605396 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.00605089 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0060439 |
| ZNF423 | zinc finger protein 423 | 0.00599295 |
| SLC27A2 | solute carrier family 27 (fatty acid transporter), member 2 | 0.00598026 |
| CCNE1 | cyclin E1 | 0.00597193 |
| MUC1 | mucin 1, cell surface associated | 0.00596392 |
| OSBPL3 | oxysterol binding protein-like 3 | 0.00595861 |
| CEL | carboxyl ester lipase | 0.00595802 |
| NDUFS7 | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 0.00595687 |
| CHAC1 | ChaC glutathione-specific gamma-glutamylcyclotransferase 1 | 0.00594532 |
| PPL | periplakin | 0.00593059 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.00592885 |
| NID2 | nidogen 2 (osteonidogen) | 0.00591331 |
| RGS19 | regulator of G-protein signaling 19 | 0.00589062 |
| PHLDA2 | pleckstrin homology-like domain, family A, member 2 | 0.00588079 |
| DEFA4 | defensin, alpha 4, corticostatin | 0.00586057 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.00585642 |
| TXN | thioredoxin | 0.00585108 |
| TECR | trans-2,3-enoyl-CoA reductase | 0.00584548 |
| CTBP2 | C-terminal binding protein 2 | 0.00583017 |
| MYL1 | myosin, light chain 1, alkali; skeletal, fast | 0.0058279 |
| ESR1 | estrogen receptor 1 | 0.00582482 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | 0.0058167 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.00579032 |
| ASPN | asporin | 0.00578107 |
| ELN | elastin | 0.00577994 |
| AMH | anti-Mullerian hormone | 0.00577348 |
| PDLIM3 | PDZ and LIM domain 3 | 0.00576486 |
| SDC2 | syndecan 2 | 0.00576283 |
| INAVA | innate immunity activator | 0.0057579 |
| ZNF91 | zinc finger protein 91 | 0.00573913 |
| RIDA | reactive intermediate imine deaminase A homolog | 0.00573673 |
| MYL6B | myosin, light chain 6B, alkali, smooth muscle and non-muscle | 0.0057269 |
| CCND3 | cyclin D3 | 0.00572626 |
| SWAP70 | SWAP switching B-cell complex 70kDa subunit | 0.00570934 |
| HMGCS2 | 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) | 0.00570717 |
| EMX2 | empty spiracles homeobox 2 | 0.00570473 |
| SHMT1 | serine hydroxymethyltransferase 1 (soluble) | 0.00570322 |
| HIST1H2BD | histone cluster 1, H2bd | 0.00568009 |
| PTGER2 | prostaglandin E receptor 2 (subtype EP2), 53kDa | 0.00567534 |
| S100A12 | S100 calcium binding protein A12 | 0.00567386 |
| CSK | c-src tyrosine kinase | 0.00566323 |
| SLC17A3 | solute carrier family 17 (organic anion transporter), member 3 | 0.00564126 |
| CPT1A | carnitine palmitoyltransferase 1A (liver) | 0.00563806 |
| PXDC1 | PX domain containing 1 | 0.00563309 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.00562972 |
| PDLIM5 | PDZ and LIM domain 5 | 0.00561271 |
| HERC2 | HECT and RLD domain containing E3 ubiquitin protein ligase 2 | 0.00560924 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | 0.00560585 |
| ENG | endoglin | 0.00560509 |
| AQP3 | aquaporin 3 (Gill blood group) | 0.00559046 |
| GAMT | guanidinoacetate N-methyltransferase | 0.00557943 |
| ADCY9 | adenylate cyclase 9 | 0.00557657 |
| TUBA4A | tubulin, alpha 4a | 0.0055683 |
| DUSP1 | dual specificity phosphatase 1 | 0.00556661 |
| ACTA1 | actin, alpha 1, skeletal muscle | 0.00556179 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | 0.00555935 |
| NPDC1 | neural proliferation, differentiation and control, 1 | 0.00554714 |
| DACH1 | dachshund family transcription factor 1 | 0.00554255 |
| IFRD2 | interferon-related developmental regulator 2 | 0.00554049 |
| OSBPL1A | oxysterol binding protein-like 1A | 0.00552179 |
| ALDOA | aldolase A, fructose-bisphosphate | 0.00551906 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | 0.00550781 |
| TXNL4A | thioredoxin-like 4A | 0.0054995 |
| MBD2 | methyl-CpG binding domain protein 2 | 0.00549397 |
| ALAS1 | 5'-aminolevulinate synthase 1 | 0.00548527 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | 0.00548337 |
| EPS8L2 | EPS8-like 2 | 0.00547634 |
| FSCN1 | fascin actin-bundling protein 1 | 0.00547505 |
| COX17 | COX17 cytochrome c oxidase copper chaperone | 0.00546939 |
| STX3 | syntaxin 3 | 0.00546643 |
| LY6E | lymphocyte antigen 6 complex, locus E | 0.00546443 |
| DCN | decorin | 0.00546441 |
| VCAM1 | vascular cell adhesion molecule 1 | 0.00545814 |
| FUT1 | fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) | 0.00545274 |
| TRAPPC6A | trafficking protein particle complex 6A | 0.00545214 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.00543856 |
| COX5A | cytochrome c oxidase subunit Va | 0.00542479 |
| NUTF2 | nuclear transport factor 2 | 0.00540035 |
| MPO | myeloperoxidase | 0.00539485 |
| CLIC3 | chloride intracellular channel 3 | 0.00538962 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.00538466 |
| SPON1 | spondin 1, extracellular matrix protein | 0.00538288 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.00537664 |
| AEBP1 | AE binding protein 1 | 0.00537545 |
| ZNF264 | zinc finger protein 264 | 0.00536855 |
| Symbol | Name | Standardized Value |
|---|---|---|
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.0153022 |
| ADO | 2-aminoethanethiol (cysteamine) dioxygenase | -0.0125733 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0119361 |
| KDM5D | lysine (K)-specific demethylase 5D | -0.0115123 |
| BCHE | butyrylcholinesterase | -0.0113128 |
| TUBB2A | tubulin, beta 2A class IIa | -0.0113033 |
| EIF1AY | eukaryotic translation initiation factor 1A, Y-linked | -0.0107864 |
| NIBAN1 | niban apoptosis regulator 1 | -0.0102239 |
| NRN1 | neuritin 1 | -0.0100958 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | -0.00995322 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0097467 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.00941113 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.00923178 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.00907684 |
| GPC3 | glypican 3 | -0.00906465 |
| SLC16A1 | solute carrier family 16 (monocarboxylate transporter), member 1 | -0.00905361 |
| S100B | S100 calcium binding protein B | -0.00849215 |
| A2M | alpha-2-macroglobulin | -0.00838114 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0083451 |
| LBH | limb bud and heart development | -0.00828856 |
| FCGBP | Fc fragment of IgG binding protein | -0.00819573 |
| AKR1B10 | aldo-keto reductase family 1, member B10 (aldose reductase) | -0.00794628 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.00791731 |
| PTPRZ1 | protein tyrosine phosphatase, receptor-type, Z polypeptide 1 | -0.00786108 |
| CD99 | CD99 molecule | -0.00784533 |
| CCR7 | chemokine (C-C motif) receptor 7 | -0.00783757 |
| TYRP1 | tyrosinase-related protein 1 | -0.00777323 |
| CHN2 | chimerin 2 | -0.00777053 |
| IQCG | IQ motif containing G | -0.00772023 |
| TKTL1 | transketolase-like 1 | -0.00771201 |
| SRC | SRC proto-oncogene, non-receptor tyrosine kinase | -0.00762499 |
| EGR2 | early growth response 2 | -0.00759806 |
| STEAP1 | six transmembrane epithelial antigen of the prostate 1 | -0.00757764 |
| ZNF266 | zinc finger protein 266 | -0.00757192 |
| ACP3 | acid phosphatase 3 | -0.00750505 |
| PLP1 | proteolipid protein 1 | -0.00747106 |
| CHI3L2 | chitinase 3-like 2 | -0.00746664 |
| IL2RB | interleukin 2 receptor, beta | -0.00741632 |
| SEPP1 | selenoprotein P, plasma, 1 | -0.00741145 |
| SSX1 | synovial sarcoma, X breakpoint 1 | -0.00733269 |
| PRAME | preferentially expressed antigen in melanoma | -0.00729903 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | -0.00729814 |
| TMEM45A | transmembrane protein 45A | -0.00727362 |
| CD2 | CD2 molecule | -0.00716212 |
| ZNF226 | zinc finger protein 226 | -0.00711377 |
| CPVL | carboxypeptidase, vitellogenic-like | -0.00710446 |
| KRT6A | keratin 6A, type II | -0.00705983 |
| PMEL | premelanosome protein | -0.00704005 |
| COPS7A | COP9 signalosome subunit 7A | -0.00703242 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.00698957 |
| SOAT1 | sterol O-acyltransferase 1 | -0.00697696 |
| GREB1 | growth regulation by estrogen in breast cancer 1 | -0.00694802 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.00693927 |
| PRF1 | perforin 1 (pore forming protein) | -0.00691059 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.00689903 |
| RRAGA | Ras-related GTP binding A | -0.0068753 |
| MAOA | monoamine oxidase A | -0.00684703 |
| CD1E | CD1e molecule | -0.00683216 |
| SI | sucrase-isomaltase (alpha-glucosidase) | -0.00682044 |
| ATXN1 | ataxin 1 | -0.00677135 |
| COL15A1 | collagen, type XV, alpha 1 | -0.00676579 |
| TGFBR3 | transforming growth factor, beta receptor III | -0.00675534 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.00670773 |
| CST3 | cystatin C | -0.0066844 |
| GDI2 | GDP dissociation inhibitor 2 | -0.00662863 |
| COL4A6 | collagen, type IV, alpha 6 | -0.00661485 |
| SNAP25 | synaptosomal-associated protein, 25kDa | -0.00660182 |
| KRT1 | keratin 1, type II | -0.00659374 |
| TREM1 | triggering receptor expressed on myeloid cells 1 | -0.00658492 |
| STK17A | serine/threonine kinase 17a | -0.00658218 |
| GPM6B | glycoprotein M6B | -0.00657407 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | -0.00653973 |
| CSRP3 | cysteine and glycine-rich protein 3 (cardiac LIM protein) | -0.00652665 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0064928 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.00646708 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.00645986 |
| FBXO11 | F-box protein 11 | -0.00643422 |
| GZMH | granzyme H (cathepsin G-like 2, protein h-CCPX) | -0.00640976 |
| KRT17 | keratin 17, type I | -0.00640817 |
| ZNF410 | zinc finger protein 410 | -0.00640682 |
| CCT4 | chaperonin containing TCP1, subunit 4 (delta) | -0.00639503 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.00637322 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.00637098 |
| ARG2 | arginase 2 | -0.00636351 |
| TP63 | tumor protein p63 | -0.00634773 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.00634325 |
| MLANA | melan-A | -0.00633577 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.00630286 |
| ALDH9A1 | aldehyde dehydrogenase 9 family, member A1 | -0.00629572 |
| GPC4 | glypican 4 | -0.00627155 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0062682 |
| OLFM4 | olfactomedin 4 | -0.00623098 |
| IGFBP1 | insulin-like growth factor binding protein 1 | -0.00622103 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.00620597 |
| XPO7 | exportin 7 | -0.00620563 |
| CAPRIN1 | cell cycle associated protein 1 | -0.00619505 |
| LOR | loricrin | -0.00618288 |
| KRT14 | keratin 14, type I | -0.00617923 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.00614203 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.00614107 |
| MIA3 | melanoma inhibitory activity family, member 3 | -0.00613383 |
| TYR | tyrosinase | -0.00612608 |
| SIRT3 | sirtuin 3 | -0.00610249 |
| CCL18 | chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated) | -0.00606367 |
| TMC5 | transmembrane channel-like 5 | -0.0060506 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.00604966 |
| KIFAP3 | kinesin-associated protein 3 | -0.00601672 |
| FABP7 | fatty acid binding protein 7, brain | -0.00600848 |
| CD1D | CD1d molecule | -0.00599963 |
| COPA | coatomer protein complex, subunit alpha | -0.00599407 |
| AIM2 | absent in melanoma 2 | -0.00597918 |
| XCL1 | chemokine (C motif) ligand 1 | -0.00597556 |
| DHRS11 | dehydrogenase/reductase (SDR family) member 11 | -0.00594736 |
| MPPED2 | metallophosphoesterase domain containing 2 | -0.00594253 |
| RORA | RAR-related orphan receptor A | -0.00592531 |
| CD1B | CD1b molecule | -0.00590301 |
| SMARCA2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 | -0.00586554 |
| PCCB | propionyl CoA carboxylase, beta polypeptide | -0.0058575 |
| CPD | carboxypeptidase D | -0.00584156 |
| RELB | v-rel avian reticuloendotheliosis viral oncogene homolog B | -0.00583269 |
| RALB | v-ral simian leukemia viral oncogene homolog B | -0.00583017 |
| DNMBP | dynamin binding protein | -0.00582835 |
| WWOX | WW domain containing oxidoreductase | -0.00582728 |
| TNFSF4 | tumor necrosis factor (ligand) superfamily, member 4 | -0.00582571 |
| TPTE | transmembrane phosphatase with tensin homology | -0.00579747 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.00577402 |
| SFN | stratifin | -0.00577288 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | -0.00575536 |
| TRIB2 | tribbles pseudokinase 2 | -0.00573255 |
| C1ORF115 | chromosome 1 open reading frame 115 | -0.00571681 |
| SPRR1B | small proline-rich protein 1B | -0.0057111 |
| KRT15 | keratin 15, type I | -0.00568338 |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | -0.00568036 |
| RHOA | ras homolog family member A | -0.00567241 |
| GYG2 | glycogenin 2 | -0.00567145 |
| ATP1A1 | ATPase, Na+/K+ transporting, alpha 1 polypeptide | -0.00565687 |
| SETMAR | SET domain and mariner transposase fusion gene | -0.00565324 |
| NLGN4X | neuroligin 4, X-linked | -0.00564653 |
| CSTA | cystatin A (stefin A) | -0.00562029 |
| HSPA12A | heat shock 70kDa protein 12A | -0.00559468 |
| GSTA4 | glutathione S-transferase alpha 4 | -0.00556254 |
| S100A7 | S100 calcium binding protein A7 | -0.0055618 |
| SPARCL1 | SPARC-like 1 (hevin) | -0.00555919 |
| KLK2 | kallikrein-related peptidase 2 | -0.00555385 |
| SSPN | sarcospan | -0.00555052 |
| PHB2 | prohibitin 2 | -0.00553836 |
| COL21A1 | collagen, type XXI, alpha 1 | -0.00552323 |
| MLH1 | mutL homolog 1 | -0.0055119 |
| TMEM255A | transmembrane protein 255A | -0.00550651 |
| ITM2A | integral membrane protein 2A | -0.00549628 |
| REG3A | regenerating islet-derived 3 alpha | -0.00548018 |
| ARMCX6 | armadillo repeat containing, X-linked 6 | -0.00546827 |
| CCL4 | chemokine (C-C motif) ligand 4 | -0.00544136 |
| UBE2E3 | ubiquitin-conjugating enzyme E2E 3 | -0.00544084 |
| KYNU | kynureninase | -0.00543367 |
| CCPG1 | cell cycle progression 1 | -0.00541557 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.00540554 |
| AFP | alpha-fetoprotein | -0.00540381 |
| KCNN2 | potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 2 | -0.00540159 |
| IRS2 | insulin receptor substrate 2 | -0.00538483 |
| PAQR3 | progestin and adipoQ receptor family member III | -0.00537183 |
| PEX12 | peroxisomal biogenesis factor 12 | -0.00536054 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0053539 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.00533261 |
| BCL2A1 | BCL2-related protein A1 | -0.00532204 |
| CHIC2 | cysteine-rich hydrophobic domain 2 | -0.00532085 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.00531718 |
| POLB | polymerase (DNA directed), beta | -0.0053091 |
| ACKR1 | atypical chemokine receptor 1 (Duffy blood group) | -0.00530736 |
| APOC2 | apolipoprotein C-II | -0.00530195 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.00529333 |
| NCAM1 | neural cell adhesion molecule 1 | -0.00527444 |
| TUBB2B | tubulin, beta 2B class IIb | -0.0052649 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.00525684 |
| ENTPD1 | ectonucleoside triphosphate diphosphohydrolase 1 | -0.00524942 |
| SCN3A | sodium channel, voltage gated, type III alpha subunit | -0.00522564 |
| LY6D | lymphocyte antigen 6 complex, locus D | -0.0052246 |
| IFT52 | intraflagellar transport 52 | -0.00522236 |
| KAT7 | K(lysine) acetyltransferase 7 | -0.00521535 |
| GSTM3 | glutathione S-transferase mu 3 (brain) | -0.00521249 |
| BCL11B | B-cell CLL/lymphoma 11B (zinc finger protein) | -0.00520916 |
| PTBP2 | polypyrimidine tract binding protein 2 | -0.00519948 |
| ADRA2A | adrenoceptor alpha 2A | -0.00519497 |
| TIMM22 | translocase of inner mitochondrial membrane 22 homolog (yeast) | -0.00518626 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.00516669 |
| PLA2G5 | phospholipase A2, group V | -0.00515972 |
| MAGEA3 | melanoma antigen family A3 | -0.00514697 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0051412 |
| GIMAP5 | GTPase, IMAP family member 5 | -0.00512838 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0051225 |
| CD86 | CD86 molecule | -0.00512207 |
| MBNL3 | muscleblind-like splicing regulator 3 | -0.0051203 |
| TSPYL5 | TSPY-like 5 | -0.00511577 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.00511104 |
| KLHL7 | kelch-like family member 7 | -0.00511091 |
| RNFT2 | ring finger protein, transmembrane 2 | -0.00510925 |
| DHTKD1 | dehydrogenase E1 and transketolase domain containing 1 | -0.00509875 |
| ABCG2 | ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) | -0.00509286 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.00508281 |
| PLAT | plasminogen activator, tissue | -0.00507508 |
| AP1S2 | adaptor-related protein complex 1, sigma 2 subunit | -0.00507391 |
| PKP1 | plakophilin 1 | -0.00506855 |
| F13A1 | coagulation factor XIII, A1 polypeptide | -0.0050655 |
| CCL20 | chemokine (C-C motif) ligand 20 | -0.00506401 |
| RNF167 | ring finger protein 167 | -0.00506033 |
| TSPAN8 | tetraspanin 8 | -0.00505752 |
| FGR | FGR proto-oncogene, Src family tyrosine kinase | -0.00505736 |
| COCH | cochlin | -0.00505562 |
| ALG13 | ALG13, UDP-N-acetylglucosaminyltransferase subunit | -0.00505404 |
| NKX2-2 | NK2 homeobox 2 | -0.00504834 |
| EPAS1 | endothelial PAS domain protein 1 | -0.00504542 |
| PSMD10 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 10 | -0.00504341 |
| NTS | neurotensin | -0.00502888 |
| SEPTIN9 | septin 9 | -0.00502582 |
| PGC | progastricsin (pepsinogen C) | -0.00502424 |
| LCK | LCK proto-oncogene, Src family tyrosine kinase | -0.00501837 |
| B4GALT4 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4 | -0.00501011 |
| KHNYN | KH and NYN domain containing | -0.00500823 |
| CCL5 | chemokine (C-C motif) ligand 5 | -0.00500481 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | -0.00499918 |
| CSN3 | casein kappa | -0.00499064 |
| TMEM135 | transmembrane protein 135 | -0.00498953 |
| AQP9 | aquaporin 9 | -0.00498818 |
| MARCH8 | membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase | -0.0049876 |
| SHTN1 | shootin 1 | -0.00498406 |
| TMEM100 | transmembrane protein 100 | -0.00498194 |
| FAM168A | family with sequence similarity 168, member A | -0.00498175 |
| SNX10 | sorting nexin 10 | -0.00497523 |
| GPR65 | G protein-coupled receptor 65 | -0.00496703 |
| ACP6 | acid phosphatase 6, lysophosphatidic | -0.00496416 |
| VLDLR | very low density lipoprotein receptor | -0.00496266 |
| SORD | sorbitol dehydrogenase | -0.00496031 |
| NR0B1 | nuclear receptor subfamily 0, group B, member 1 | -0.00495592 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.00495514 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.00494973 |
| CD3E | CD3e molecule, epsilon (CD3-TCR complex) | -0.00494612 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.00494483 |
| PER3 | period circadian clock 3 | -0.00494336 |
| MARS1 | methionyl-tRNA synthetase 1 | -0.00492971 |
| NOVA1 | neuro-oncological ventral antigen 1 | -0.00492922 |
| BBS4 | Bardet-Biedl syndrome 4 | -0.00492702 |
| NAP1L2 | nucleosome assembly protein 1-like 2 | -0.00492075 |
| GPD1L | glycerol-3-phosphate dehydrogenase 1-like | -0.00491436 |
| FOLH1B | folate hydrolase 1B | -0.00491374 |
| USP15 | ubiquitin specific peptidase 15 | -0.00491278 |
| F8 | coagulation factor VIII, procoagulant component | -0.00490959 |
| CYP26B1 | cytochrome P450, family 26, subfamily B, polypeptide 1 | -0.00490494 |
| RWDD2A | RWD domain containing 2A | -0.00490128 |
| RTRAF | RNA transcription, translation and transport factor | -0.00489902 |
| CCKBR | cholecystokinin B receptor | -0.00489111 |
