| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.236773 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.207942 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.188117 |
| YAP1 | Yes-associated protein 1 | 0.129506 |
| AREG | amphiregulin | 0.113903 |
| PCDH7 | protocadherin 7 | 0.10172 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0904518 |
| NLGN1 | neuroligin 1 | 0.0867066 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0833426 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0746228 |
| CALR | calreticulin | 0.0744614 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0733743 |
| IPO7 | importin 7 | 0.0708834 |
| PCBP2 | poly(rC) binding protein 2 | 0.0692123 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0636334 |
| VIM | vimentin | 0.0620518 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0591667 |
| POTEF | POTE ankyrin domain family, member F | 0.0579618 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0567474 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0562902 |
| PDGFC | platelet derived growth factor C | 0.0554952 |
| TENM3 | teneurin transmembrane protein 3 | 0.0553991 |
| ACTG1 | actin gamma 1 | 0.0545626 |
| TMEM41B | transmembrane protein 41B | 0.0541017 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0515358 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0513136 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.049193 |
| AHNAK | AHNAK nucleoprotein | 0.0487321 |
| DLC1 | DLC1 Rho GTPase activating protein | 0.047851 |
| MPG | N-methylpurine-DNA glycosylase | 0.0469193 |
| ANXA1 | annexin A1 | 0.0467182 |
| MYPN | myopalladin | 0.0462352 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.046171 |
| DST | dystonin | 0.0460948 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0456205 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0455365 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0445289 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0444531 |
| EDARADD | EDAR-associated death domain | 0.0440869 |
| TPM3 | tropomyosin 3 | 0.0435184 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0417298 |
| MMP12 | matrix metallopeptidase 12 | 0.0414662 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0412607 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0408722 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0401464 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0387522 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0381354 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0373812 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0367907 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0360408 |
| RRM2 | ribonucleotide reductase M2 | 0.0358211 |
| ENO1 | enolase 1, (alpha) | 0.0355865 |
| NEBL | nebulette | 0.0354576 |
| CENPF | centromere protein F, 350/400kDa | 0.0351008 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0346495 |
| RPL3 | ribosomal protein L3 | 0.0344448 |
| TXNRD1 | thioredoxin reductase 1 | 0.0341999 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0336592 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0335823 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0325562 |
| PTMS | parathymosin | 0.0320261 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0319774 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0316512 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0313747 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0313727 |
| CPOX | coproporphyrinogen oxidase | 0.0312748 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0311491 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0296829 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0292179 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.028948 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0287494 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0281843 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0280292 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0275061 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0274705 |
| PCM1 | pericentriolar material 1 | 0.0266955 |
| KIF5B | kinesin family member 5B | 0.026335 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0262242 |
| SET | SET nuclear proto-oncogene | 0.0260413 |
| FAT1 | FAT atypical cadherin 1 | 0.025911 |
| MED13L | mediator complex subunit 13-like | 0.0258626 |
| CCN2 | cellular communication network factor 2 | 0.0257664 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0256336 |
| CCNL1 | cyclin L1 | 0.0256081 |
| ASPH | aspartate beta-hydroxylase | 0.0253092 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.025154 |
| CDK17 | cyclin-dependent kinase 17 | 0.0244937 |
| GJA1 | gap junction protein, alpha 1, 43kDa | 0.024397 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0242273 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.024218 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0240776 |
| NEGR1 | neuronal growth regulator 1 | 0.0240501 |
| MAP3K14 | mitogen-activated protein kinase kinase kinase 14 | 0.0239477 |
| EPHA6 | EPH receptor A6 | 0.0238055 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0237234 |
| CLDND1 | claudin domain containing 1 | 0.0237042 |
| NR5A2 | nuclear receptor subfamily 5, group A, member 2 | 0.0235925 |
| CDK6 | cyclin-dependent kinase 6 | 0.023547 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | 0.0234238 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0225982 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.261774 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0661361 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0644507 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0633486 |
| EHBP1 | EH domain binding protein 1 | -0.0594099 |
| EGR1 | early growth response 1 | -0.0582084 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0515447 |
| RPS24 | ribosomal protein S24 | -0.0439702 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0438566 |
| RPS27A | ribosomal protein S27a | -0.0434312 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0433434 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0425965 |
| RPL35A | ribosomal protein L35a | -0.0418017 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0400392 |
| RPS6 | ribosomal protein S6 | -0.0393424 |
| RPL37A | ribosomal protein L37a | -0.0378883 |
| RPL11 | ribosomal protein L11 | -0.0353353 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0353312 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0344599 |
| FTL | ferritin, light polypeptide | -0.0342961 |
| RPS3 | ribosomal protein S3 | -0.0341119 |
| HMGA1 | high mobility group AT-hook 1 | -0.0339506 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0335821 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.033405 |
| RAD51B | RAD51 paralog B | -0.0324298 |
| PCNP | PEST proteolytic signal containing nuclear protein | -0.0323909 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0321379 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0321375 |
| CMSS1 | cms1 ribosomal small subunit homolog (yeast) | -0.0319604 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0318126 |
| GNAS | GNAS complex locus | -0.0317093 |
| RPL34 | ribosomal protein L34 | -0.0309929 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0307739 |
| FMNL2 | formin-like 2 | -0.0306692 |
| RPS12 | ribosomal protein S12 | -0.0293662 |
| RPL38 | ribosomal protein L38 | -0.0289264 |
| RPS8 | ribosomal protein S8 | -0.0288256 |
| S100A10 | S100 calcium binding protein A10 | -0.028629 |
| GPHN | gephyrin | -0.0284616 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0284442 |
| RPL31 | ribosomal protein L31 | -0.0284297 |
| RPL12 | ribosomal protein L12 | -0.0282711 |
| TSPAN5 | tetraspanin 5 | -0.0280325 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0277663 |
| RPS10 | ribosomal protein S10 | -0.0275943 |
| NF1 | neurofibromin 1 | -0.0274447 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0272795 |
| CUX1 | cut-like homeobox 1 | -0.0267742 |
| TMSB10 | thymosin beta 10 | -0.0266761 |
| RPL26 | ribosomal protein L26 | -0.0264314 |
| RPS15 | ribosomal protein S15 | -0.0262231 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0256814 |
| RPL37 | ribosomal protein L37 | -0.0255877 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0255321 |
| NSD2 | nuclear receptor binding SET domain protein 2 | -0.0255143 |
| LARS1 | leucyl-tRNA synthetase 1 | -0.0252958 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0248832 |
| SYT1 | synaptotagmin I | -0.0248803 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0247606 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0246733 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0246248 |
| RASAL2 | RAS protein activator like 2 | -0.0245523 |
| RBM39 | RNA binding motif protein 39 | -0.0242727 |
| LRRC23 | leucine rich repeat containing 23 | -0.0242433 |
| H1-0 | H1.0 linker histone | -0.0240449 |
| RPS29 | ribosomal protein S29 | -0.0239123 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0235243 |
| SBF2 | SET binding factor 2 | -0.0232599 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0230617 |
| ADIPOR2 | adiponectin receptor 2 | -0.0230297 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0229715 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.02277 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0224746 |
| DTNA | dystrobrevin, alpha | -0.0223753 |
| ELP4 | elongator acetyltransferase complex subunit 4 | -0.0222975 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0215873 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0214773 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.021413 |
| RAB7A | RAB7A, member RAS oncogene family | -0.021398 |
| FBXO11 | F-box protein 11 | -0.0212457 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0211549 |
| AK1 | adenylate kinase 1 | -0.0211491 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0211453 |
| KLHL24 | kelch-like family member 24 | -0.0211208 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0210759 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0209941 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0209839 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0206976 |
| RPS25 | ribosomal protein S25 | -0.0206279 |
| CLDN1 | claudin 1 | -0.0202883 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0201299 |
| MAP4 | microtubule-associated protein 4 | -0.0201072 |
| RHOA | ras homolog family member A | -0.0200906 |
| SPAG9 | sperm associated antigen 9 | -0.0199871 |
| FDPS | farnesyl diphosphate synthase | -0.0199057 |
| RPS16 | ribosomal protein S16 | -0.0197768 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0197089 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0197026 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0196024 |
| RPL27A | ribosomal protein L27a | -0.0195817 |
