| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.190048 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.135921 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.103906 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0940414 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.091948 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0815437 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0797382 |
| SMAD3 | SMAD family member 3 | 0.0692323 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0673855 |
| KYNU | kynureninase | 0.0657969 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0653331 |
| CD44 | CD44 molecule (Indian blood group) | 0.0636273 |
| AHNAK | AHNAK nucleoprotein | 0.061374 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0602606 |
| NRP2 | neuropilin 2 | 0.0600435 |
| INTS6 | integrator complex subunit 6 | 0.0595788 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0583197 |
| TLE4 | transducin-like enhancer of split 4 | 0.0515104 |
| POTEF | POTE ankyrin domain family, member F | 0.0512198 |
| VCL | vinculin | 0.0485656 |
| RPS4X | ribosomal protein S4, X-linked | 0.0467801 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0463722 |
| CALR | calreticulin | 0.0461557 |
| MYOF | myoferlin | 0.0458756 |
| PAX8 | paired box 8 | 0.0436616 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0425828 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0408573 |
| TUT7 | terminal uridylyl transferase 7 | 0.0402359 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0399823 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0396189 |
| APP | amyloid beta (A4) precursor protein | 0.0393543 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0386145 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0380989 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0380293 |
| ACTG1 | actin gamma 1 | 0.0369187 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.036645 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0362971 |
| CENPF | centromere protein F, 350/400kDa | 0.0357718 |
| SP100 | SP100 nuclear antigen | 0.0347221 |
| MX1 | MX dynamin-like GTPase 1 | 0.0343732 |
| FHL2 | four and a half LIM domains 2 | 0.0342928 |
| NAV2 | neuron navigator 2 | 0.0341896 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0340936 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0339165 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0335056 |
| RDH10 | retinol dehydrogenase 10 (all-trans) | 0.0332576 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.03222 |
| COPA | coatomer protein complex, subunit alpha | 0.0317051 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0316752 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0313738 |
| RND3 | Rho family GTPase 3 | 0.0308313 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.03079 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0289214 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | 0.0285388 |
| IFI44L | interferon-induced protein 44-like | 0.028355 |
| JAK1 | Janus kinase 1 | 0.0283358 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0281248 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0274001 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0273881 |
| PUM3 | pumilio RNA binding family member 3 | 0.0273773 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0272208 |
| SLC4A4 | solute carrier family 4 (sodium bicarbonate cotransporter), member 4 | 0.0270954 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0267337 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0267067 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.02667 |
| EXOC4 | exocyst complex component 4 | 0.0266052 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0256611 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0253997 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0249259 |
| ANXA5 | annexin A5 | 0.0246991 |
| LYST | lysosomal trafficking regulator | 0.0246899 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.024662 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0244183 |
| ENAH | enabled homolog (Drosophila) | 0.0242637 |
| GOLGB1 | golgin B1 | 0.0238187 |
| CA12 | carbonic anhydrase XII | 0.0237448 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0235415 |
| FAM20C | family with sequence similarity 20, member C | 0.0234041 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0233358 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0231215 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0229469 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | 0.022908 |
| ANXA1 | annexin A1 | 0.0228169 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0226291 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0225995 |
| USP47 | ubiquitin specific peptidase 47 | 0.0225565 |
| USO1 | USO1 vesicle transport factor | 0.0224871 |
| MB21D2 | Mab-21 domain containing 2 | 0.0223591 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0221673 |
| ELOVL5 | ELOVL fatty acid elongase 5 | 0.0220253 |
| ADAR | adenosine deaminase, RNA-specific | 0.0219585 |
| HDAC9 | histone deacetylase 9 | 0.0219224 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0218677 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0217537 |
| NIBAN1 | niban apoptosis regulator 1 | 0.0215972 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.0212328 |
| GPC5 | glypican 5 | 0.0211023 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0207519 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0205601 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.020556 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.216741 |
| NDRG1 | N-myc downstream regulated 1 | -0.0871077 |
| VIM | vimentin | -0.0657979 |
| PTMA | prothymosin, alpha | -0.0643178 |
| FTL | ferritin, light polypeptide | -0.0631703 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0588186 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0584233 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0545086 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0538692 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0531139 |
| CTSD | cathepsin D | -0.0523569 |
| RPL37A | ribosomal protein L37a | -0.0515144 |
| RTN4 | reticulon 4 | -0.0506593 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0489881 |
| FN1 | fibronectin 1 | -0.0480319 |
| RPS6 | ribosomal protein S6 | -0.0467277 |
| HLA-B | major histocompatibility complex, class I, B | -0.0456086 |
| RPL37 | ribosomal protein L37 | -0.044574 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0439654 |
| B2M | beta-2-microglobulin | -0.0436151 |
| RPS13 | ribosomal protein S13 | -0.0433844 |
| RPS17 | ribosomal protein S17 | -0.0423599 |
| RPS27A | ribosomal protein S27a | -0.0415602 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0407645 |
| RPL23 | ribosomal protein L23 | -0.0397317 |
| RPL35A | ribosomal protein L35a | -0.0397067 |
| RPS24 | ribosomal protein S24 | -0.0381853 |
| CP | ceruloplasmin (ferroxidase) | -0.0381128 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.036517 |
| RPS27 | ribosomal protein S27 | -0.0364928 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0357128 |
| PKM | pyruvate kinase, muscle | -0.0356917 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0356097 |
| RUNX1 | runt-related transcription factor 1 | -0.0354172 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0354061 |
| TMSB10 | thymosin beta 10 | -0.035195 |
| RPL31 | ribosomal protein L31 | -0.0350836 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0350354 |
| CD82 | CD82 molecule | -0.0349639 |
| GPC6 | glypican 6 | -0.0347811 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0347098 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0339107 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0337053 |
| TRIM56 | tripartite motif containing 56 | -0.0337033 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0334085 |
| JMJD1C | jumonji domain containing 1C | -0.0330025 |
| DIAPH3 | diaphanous-related formin 3 | -0.0324498 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0320631 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0319008 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | -0.0318913 |
| OXR1 | oxidation resistance 1 | -0.0317646 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0310673 |
| RPS12 | ribosomal protein S12 | -0.0309759 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0305541 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0303909 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0303576 |
| SBF2 | SET binding factor 2 | -0.0303518 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0299624 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0298938 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0296727 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0295633 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0290598 |
| MAP1B | microtubule-associated protein 1B | -0.0289943 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0288323 |
| CDCP1 | CUB domain containing protein 1 | -0.028635 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | -0.0286195 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | -0.0277505 |
| RPL26 | ribosomal protein L26 | -0.0273034 |
| RPS5 | ribosomal protein S5 | -0.0268332 |
| MMP7 | matrix metallopeptidase 7 | -0.0266583 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0266561 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0266274 |
| RRM2 | ribonucleotide reductase M2 | -0.0265846 |
| RNF220 | ring finger protein 220 | -0.0262266 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0262165 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.026071 |
| SPAG9 | sperm associated antigen 9 | -0.026042 |
| APOL1 | apolipoprotein L, 1 | -0.0257513 |
| PGK1 | phosphoglycerate kinase 1 | -0.0257187 |
| HLA-A | major histocompatibility complex, class I, A | -0.0256124 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.02548 |
| RPS29 | ribosomal protein S29 | -0.02545 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0254381 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0253449 |
| EFNA5 | ephrin-A5 | -0.0251271 |
| RPS21 | ribosomal protein S21 | -0.0250657 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0250614 |
| ANKRD33B | ankyrin repeat domain 33B | -0.0245907 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0245568 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0244923 |
| POM121 | POM121 transmembrane nucleoporin | -0.0244179 |
| VMP1 | vacuole membrane protein 1 | -0.0242148 |
| ANXA4 | annexin A4 | -0.0240927 |
| WDFY3 | WD repeat and FYVE domain containing 3 | -0.0239492 |
| RPS14 | ribosomal protein S14 | -0.0238399 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0238055 |
| RALA | v-ral simian leukemia viral oncogene homolog A (ras related) | -0.0237715 |
| RPS20 | ribosomal protein S20 | -0.0236806 |
| RPS19 | ribosomal protein S19 | -0.0236243 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0235456 |
