| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.162335 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.157623 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.15653 |
| VIM | vimentin | 0.149288 |
| ACTG1 | actin gamma 1 | 0.147869 |
| AHNAK | AHNAK nucleoprotein | 0.129502 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.108485 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0902768 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0872419 |
| KYNU | kynureninase | 0.0827055 |
| LDHA | lactate dehydrogenase A | 0.0818972 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0815257 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0755496 |
| POTEF | POTE ankyrin domain family, member F | 0.0750647 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.073557 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.072772 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0724553 |
| ANXA2 | annexin A2 | 0.0720783 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0704194 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0664615 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0652191 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0643574 |
| RNF213 | ring finger protein 213 | 0.0631575 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0620782 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0595662 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0578715 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0562511 |
| ENO1 | enolase 1, (alpha) | 0.0560702 |
| SP100 | SP100 nuclear antigen | 0.0558485 |
| TMSB10 | thymosin beta 10 | 0.0545408 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0534855 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0516196 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.050636 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0498489 |
| PDLIM5 | PDZ and LIM domain 5 | 0.049584 |
| EHBP1 | EH domain binding protein 1 | 0.0485045 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0483336 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0465127 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0454379 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0439594 |
| BPTF | bromodomain PHD finger transcription factor | 0.0436468 |
| EGFR | epidermal growth factor receptor | 0.0436211 |
| ST6GAL2 | ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 | 0.0430485 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0422 |
| CENPF | centromere protein F, 350/400kDa | 0.0419987 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0414684 |
| EFNA5 | ephrin-A5 | 0.0410882 |
| TCIM | transcriptional and immune response regulator | 0.0410273 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0395942 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0395525 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0395101 |
| LMO7 | LIM domain 7 | 0.0387864 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0383104 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0373685 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0366915 |
| MYO1E | myosin IE | 0.0365928 |
| HSPA8 | heat shock 70kDa protein 8 | 0.036474 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0359851 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0357885 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | 0.0357494 |
| CUX1 | cut-like homeobox 1 | 0.0354829 |
| ASPH | aspartate beta-hydroxylase | 0.03531 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0352354 |
| PCBP2 | poly(rC) binding protein 2 | 0.0352069 |
| RPL4 | ribosomal protein L4 | 0.0352058 |
| VCL | vinculin | 0.0351715 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0350446 |
| PKM | pyruvate kinase, muscle | 0.0349856 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0339422 |
| EREG | epiregulin | 0.0339329 |
| RBPMS | RNA binding protein with multiple splicing | 0.0337472 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0331074 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0330333 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.032401 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0322744 |
| MCL1 | myeloid cell leukemia 1 | 0.031605 |
| STC1 | stanniocalcin 1 | 0.0315213 |
| MYO10 | myosin X | 0.0315036 |
| FAT1 | FAT atypical cadherin 1 | 0.0312156 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0311024 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0310706 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0302846 |
| RSPO3 | R-spondin 3 | 0.029944 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0288342 |
| ZC3H12C | zinc finger CCCH-type containing 12C | 0.0288215 |
| MKI67 | marker of proliferation Ki-67 | 0.0286477 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0284734 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0283859 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0280607 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.028036 |
| RHCG | Rh family, C glycoprotein | 0.0279463 |
| DST | dystonin | 0.0278241 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0277328 |
| S100A6 | S100 calcium binding protein A6 | 0.0275315 |
| MAP7 | microtubule-associated protein 7 | 0.0274593 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0273628 |
| DSPP | dentin sialophosphoprotein | 0.0272035 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0271685 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0269213 |
| DUSP4 | dual specificity phosphatase 4 | 0.0267864 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.122431 |
| NDRG1 | N-myc downstream regulated 1 | -0.0975956 |
| SPAG9 | sperm associated antigen 9 | -0.0917081 |
| GOLGA4 | golgin A4 | -0.0765425 |
| USP3 | ubiquitin specific peptidase 3 | -0.069764 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.069032 |
| HELZ | helicase with zinc finger | -0.0619283 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0557439 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0538611 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0523887 |
| FLNB | filamin B, beta | -0.0515429 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0514854 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0506356 |
| RTN4 | reticulon 4 | -0.0484979 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0470213 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0465562 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0465505 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0460791 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0433432 |
| SBF2 | SET binding factor 2 | -0.0422029 |
| NBAS | neuroblastoma amplified sequence | -0.0414456 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0411082 |
| RPS6 | ribosomal protein S6 | -0.040127 |
| DGKD | diacylglycerol kinase, delta 130kDa | -0.0398264 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0395334 |
| SEC24A | SEC24 family member A | -0.0385028 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0384933 |
| NUP58 | nucleoporin 58 | -0.0384725 |
| SUCO | SUN domain containing ossification factor | -0.0378774 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0377601 |
| TXNRD1 | thioredoxin reductase 1 | -0.0369766 |
| NAV2 | neuron navigator 2 | -0.0369616 |
| WDR43 | WD repeat domain 43 | -0.0367372 |
| WDR45B | WD repeat domain 45B | -0.0367327 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0355905 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0353337 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0347377 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0346084 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.034431 |
| NGLY1 | N-glycanase 1 | -0.0341915 |
| ZNF292 | zinc finger protein 292 | -0.0340511 |
| SMAD3 | SMAD family member 3 | -0.0337327 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0333691 |
| FTL | ferritin, light polypeptide | -0.0330032 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.03291 |
| MT2A | metallothionein 2A | -0.0326938 |
| TPD52 | tumor protein D52 | -0.0311884 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0311368 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0307313 |
| CEP95 | centrosomal protein 95kDa | -0.0301104 |
| GRB10 | growth factor receptor-bound protein 10 | -0.030048 |
| RNF24 | ring finger protein 24 | -0.0299855 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0298489 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0292656 |
| COG5 | component of oligomeric golgi complex 5 | -0.0282406 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | -0.0282192 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0280815 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | -0.0276084 |
| RASA2 | RAS p21 protein activator 2 | -0.0275477 |
| CLINT1 | clathrin interactor 1 | -0.0272122 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0267475 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0263163 |
| DENND4A | DENN/MADD domain containing 4A | -0.0260142 |
| AGFG1 | ArfGAP with FG repeats 1 | -0.026009 |
| SETD5 | SET domain containing 5 | -0.0259876 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0259704 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0257713 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0256838 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0256331 |
| SRP54 | signal recognition particle 54kDa | -0.025521 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0254357 |
| MSN | moesin | -0.0253371 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0246454 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | -0.0245033 |
| FA2H | fatty acid 2-hydroxylase | -0.0243802 |
| RBM39 | RNA binding motif protein 39 | -0.0243426 |
| CLTC | clathrin, heavy chain (Hc) | -0.0242886 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0242752 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0241506 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0237697 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0236971 |
| ANO6 | anoctamin 6 | -0.0235944 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0235672 |
| GOLT1B | golgi transport 1B | -0.0235175 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0234052 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.023364 |
| KCMF1 | potassium channel modulatory factor 1 | -0.023246 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.023141 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0229001 |
| MORF4L2 | mortality factor 4 like 2 | -0.022761 |
| PHF21A | PHD finger protein 21A | -0.022709 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0226153 |
| NOP58 | NOP58 ribonucleoprotein | -0.0225879 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0224415 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0222348 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0221925 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0219183 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0216987 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0216892 |
| YEATS2 | YEATS domain containing 2 | -0.0214544 |
