| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.246025 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.16645 |
| HMGA2 | high mobility group AT-hook 2 | 0.113435 |
| ACTG1 | actin gamma 1 | 0.11188 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.105468 |
| TSHZ2 | teashirt zinc finger homeobox 2 | 0.0990585 |
| ENO1 | enolase 1, (alpha) | 0.0914993 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0765092 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0730305 |
| MYOF | myoferlin | 0.0687293 |
| PRKG1 | protein kinase, cGMP-dependent, type I | 0.0669521 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0658189 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0632041 |
| AHNAK | AHNAK nucleoprotein | 0.0589941 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0589864 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0573776 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.055503 |
| POTEF | POTE ankyrin domain family, member F | 0.053866 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.051514 |
| CTBP2 | C-terminal binding protein 2 | 0.0510074 |
| PEG10 | paternally expressed 10 | 0.0507146 |
| RPL3 | ribosomal protein L3 | 0.049433 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0483722 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0468592 |
| VEGFA | vascular endothelial growth factor A | 0.0464805 |
| GMDS | GDP-mannose 4,6-dehydratase | 0.0462156 |
| IPO7 | importin 7 | 0.0450295 |
| CADM2 | cell adhesion molecule 2 | 0.0438786 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0425127 |
| ATP11A | ATPase, class VI, type 11A | 0.0424233 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0422961 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0422406 |
| THBS1 | thrombospondin 1 | 0.039838 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0391534 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0388418 |
| FRMD6 | FERM domain containing 6 | 0.038759 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0386087 |
| PCBP2 | poly(rC) binding protein 2 | 0.0383752 |
| RPL37A | ribosomal protein L37a | 0.0380165 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0366468 |
| EGFR | epidermal growth factor receptor | 0.035403 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0353753 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0350557 |
| RPL23 | ribosomal protein L23 | 0.03493 |
| RAI1 | retinoic acid induced 1 | 0.0342302 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.033394 |
| SIK3 | SIK family kinase 3 | 0.0328225 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0323173 |
| ANO6 | anoctamin 6 | 0.0321607 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0319864 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0319589 |
| RCOR1 | REST corepressor 1 | 0.03135 |
| LDHA | lactate dehydrogenase A | 0.0310761 |
| PHF3 | PHD finger protein 3 | 0.0310093 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0308368 |
| MGP | matrix Gla protein | 0.0301931 |
| FLNB | filamin B, beta | 0.030191 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0297874 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0297216 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0295052 |
| INTS6 | integrator complex subunit 6 | 0.0291969 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0290855 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0278529 |
| PLS3 | plastin 3 | 0.0272577 |
| MAP1B | microtubule-associated protein 1B | 0.0272509 |
| AGO2 | argonaute RISC catalytic component 2 | 0.0268789 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0268784 |
| PKM | pyruvate kinase, muscle | 0.0267473 |
| RPS8 | ribosomal protein S8 | 0.0266726 |
| KANK1 | KN motif and ankyrin repeat domains 1 | 0.0259686 |
| HMGA1 | high mobility group AT-hook 1 | 0.025288 |
| ADIPOR2 | adiponectin receptor 2 | 0.0251565 |
| HNRNPR | heterogeneous nuclear ribonucleoprotein R | 0.0251003 |
| YBX1 | Y box binding protein 1 | 0.0249423 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.0249093 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0248491 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0243238 |
| PDE10A | phosphodiesterase 10A | 0.0242875 |
| RPL4 | ribosomal protein L4 | 0.0241903 |
| JMJD1C | jumonji domain containing 1C | 0.0241548 |
| RPS4X | ribosomal protein S4, X-linked | 0.0241096 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0240863 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0237698 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0236107 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0235408 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.023387 |
| SERTAD2 | SERTA domain containing 2 | 0.0233204 |
| EGR1 | early growth response 1 | 0.0233171 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0231708 |
| LOXL2 | lysyl oxidase-like 2 | 0.0230509 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0228576 |
| RPS3 | ribosomal protein S3 | 0.0227208 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0225972 |
| TM9SF4 | transmembrane 9 superfamily protein member 4 | 0.0222945 |
| MEST | mesoderm specific transcript | 0.0222346 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0221872 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0221642 |
| NBEA | neurobeachin | 0.022035 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0220109 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0218583 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.152493 |
| ZNF292 | zinc finger protein 292 | -0.0827802 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0765762 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.071635 |
| QKI | QKI, KH domain containing, RNA binding | -0.068256 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.063186 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0593202 |
| CENPF | centromere protein F, 350/400kDa | -0.0589617 |
| MKI67 | marker of proliferation Ki-67 | -0.057924 |
| MEOX2 | mesenchyme homeobox 2 | -0.0564747 |
| MED13L | mediator complex subunit 13-like | -0.0561731 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0552211 |
| TPK1 | thiamin pyrophosphokinase 1 | -0.0540341 |
| ITGAV | integrin, alpha V | -0.0518384 |
| USP3 | ubiquitin specific peptidase 3 | -0.0507556 |
| NFIB | nuclear factor I/B | -0.050235 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0493512 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0483854 |
| SBF2 | SET binding factor 2 | -0.0480299 |
| H1-4 | H1.4 linker histone, cluster member | -0.0477197 |
| PTMA | prothymosin, alpha | -0.0470418 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0468343 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0454589 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0449975 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0445794 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.044528 |
| RPS2 | ribosomal protein S2 | -0.0438718 |
| RPS6 | ribosomal protein S6 | -0.0428746 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0425637 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0419242 |
| SEPTIN11 | septin 11 | -0.0416174 |
| HMGB2 | high mobility group box 2 | -0.0415962 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0414211 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0413098 |
| CENPE | centromere protein E, 312kDa | -0.0409261 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0404035 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0383272 |
| BTBD3 | BTB (POZ) domain containing 3 | -0.0383228 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0380631 |
| NFIA | nuclear factor I/A | -0.0376781 |
| DIAPH3 | diaphanous-related formin 3 | -0.0374817 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0366682 |
| RLF | rearranged L-myc fusion | -0.0365174 |
| LMO4 | LIM domain only 4 | -0.0363974 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0363782 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0362786 |
| RPS24 | ribosomal protein S24 | -0.0359673 |
| TPX2 | TPX2, microtubule-associated | -0.0358577 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.035552 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0350305 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0346673 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0346475 |
| RPL8 | ribosomal protein L8 | -0.0346153 |
| MT2A | metallothionein 2A | -0.0345576 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0335124 |
| HOXA3 | homeobox A3 | -0.0334244 |
| XPO1 | exportin 1 | -0.0333898 |
| DDX50 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 50 | -0.0332265 |
| RPL38 | ribosomal protein L38 | -0.0331499 |
| WTAP | Wilms tumor 1 associated protein | -0.033107 |
| RTN4 | reticulon 4 | -0.0328248 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0325561 |
| RNF145 | ring finger protein 145 | -0.0325115 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0324428 |
| GAS2L3 | growth arrest-specific 2 like 3 | -0.0320845 |
| WBP11 | WW domain binding protein 11 | -0.0320211 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0320144 |
| SUCO | SUN domain containing ossification factor | -0.0317901 |
| RHEB | Ras homolog enriched in brain | -0.0317768 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0316847 |
| CAPRIN1 | cell cycle associated protein 1 | -0.0313371 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0311799 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0309363 |
| PRELID2 | PRELI domain containing 2 | -0.0308326 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0308282 |
| OGA | O-GlcNAcase | -0.0306722 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0304681 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0303778 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0300132 |
| ANLN | anillin, actin binding protein | -0.0299083 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.029607 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0294588 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | -0.0293263 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0289252 |
| KIF20B | kinesin family member 20B | -0.028672 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0284481 |
| FANCI | Fanconi anemia, complementation group I | -0.0281076 |
| TMEM123 | transmembrane protein 123 | -0.0279135 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0277175 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0274545 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0272027 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0270335 |
| RPS23 | ribosomal protein S23 | -0.0269741 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0267953 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0267847 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.026649 |
| TFG | TRK-fused gene | -0.0266196 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0264706 |
| RPS15 | ribosomal protein S15 | -0.0263655 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | -0.0263219 |
