| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.139335 |
| EGFR | epidermal growth factor receptor | 0.132053 |
| EFNA5 | ephrin-A5 | 0.127657 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.117817 |
| DOCK5 | dedicator of cytokinesis 5 | 0.112519 |
| SACK1A | scaffolding CK1 anchoring protein A | 0.0993772 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0958445 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0895106 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.085342 |
| FLNB | filamin B, beta | 0.0822066 |
| MCL1 | myeloid cell leukemia 1 | 0.0787609 |
| AHNAK | AHNAK nucleoprotein | 0.0776922 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0701905 |
| RASAL2 | RAS protein activator like 2 | 0.0689337 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0668351 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0651108 |
| ABTB3 | ankyrin repeat and BTB domain containing 3 | 0.0635962 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0610848 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0608552 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0599406 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0576442 |
| HMGA2 | high mobility group AT-hook 2 | 0.0546501 |
| LAMC2 | laminin, gamma 2 | 0.0540314 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0532824 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.052367 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0519125 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0517083 |
| TXNRD1 | thioredoxin reductase 1 | 0.0514917 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0510516 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0508486 |
| TGM2 | transglutaminase 2 | 0.050649 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0502971 |
| PIP4K2A | phosphatidylinositol-5-phosphate 4-kinase, type II, alpha | 0.0496511 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0488158 |
| PLEC | plectin | 0.0480259 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0472947 |
| PMM2 | phosphomannomutase 2 | 0.0463458 |
| BMP6 | bone morphogenetic protein 6 | 0.0463385 |
| SVIL | supervillin | 0.0460835 |
| TXNIP | thioredoxin interacting protein | 0.0444242 |
| SEPTIN9 | septin 9 | 0.0431591 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0422104 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0412195 |
| SMAD3 | SMAD family member 3 | 0.0408665 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0399187 |
| SGMS2 | sphingomyelin synthase 2 | 0.0396965 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0395238 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0381671 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0380269 |
| DIAPH1 | diaphanous-related formin 1 | 0.0375953 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0369946 |
| SP100 | SP100 nuclear antigen | 0.0368832 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0368375 |
| BCL2L1 | BCL2-like 1 | 0.0364885 |
| LAMB3 | laminin, beta 3 | 0.0351729 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0350665 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0344166 |
| OSMR | oncostatin M receptor | 0.0341173 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0338403 |
| TPM3 | tropomyosin 3 | 0.0333647 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0333008 |
| GOLGB1 | golgin B1 | 0.0329353 |
| MMP1 | matrix metallopeptidase 1 | 0.0328751 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | 0.0327645 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0327597 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | 0.0326083 |
| RAPH1 | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 | 0.032497 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0324006 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0319872 |
| INTS6 | integrator complex subunit 6 | 0.0317723 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0316799 |
| DSPP | dentin sialophosphoprotein | 0.0313455 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0312995 |
| FBXO11 | F-box protein 11 | 0.0311311 |
| RUNX1 | runt-related transcription factor 1 | 0.0308532 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0306239 |
| ASPH | aspartate beta-hydroxylase | 0.030562 |
| HDAC9 | histone deacetylase 9 | 0.0303636 |
| TLN1 | talin 1 | 0.0302796 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0302582 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0302235 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0300767 |
| SLC35F3 | solute carrier family 35, member F3 | 0.0297893 |
| SEPTIN10 | septin 10 | 0.0293555 |
| MSN | moesin | 0.0285804 |
| FMNL2 | formin-like 2 | 0.0280899 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.027665 |
| CORO1C | coronin, actin binding protein, 1C | 0.0276466 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | 0.027557 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0274963 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0274937 |
| USP34 | ubiquitin specific peptidase 34 | 0.0274758 |
| TRRAP | transformation/transcription domain-associated protein | 0.0271115 |
| LAMA4 | laminin, alpha 4 | 0.0270452 |
| LARP4B | La ribonucleoprotein domain family, member 4B | 0.0270446 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0267466 |
| KLK10 | kallikrein-related peptidase 10 | 0.0267335 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0266596 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0266035 |
| ACTN4 | actinin, alpha 4 | 0.0263951 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.154561 |
| PTMA | prothymosin, alpha | -0.154262 |
| TMSB10 | thymosin beta 10 | -0.151286 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.114009 |
| HMGA1 | high mobility group AT-hook 1 | -0.101279 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.10118 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0966831 |
| S100A10 | S100 calcium binding protein A10 | -0.0848377 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0792306 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0748676 |
| LMTK2 | lemur tyrosine kinase 2 | -0.0735158 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0672556 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0596864 |
| NDRG1 | N-myc downstream regulated 1 | -0.0540405 |
| ZNF292 | zinc finger protein 292 | -0.0529594 |
| SLMAP | sarcolemma associated protein | -0.0521897 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0519844 |
| RPL35A | ribosomal protein L35a | -0.0517594 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0516257 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0509416 |
| SPAG9 | sperm associated antigen 9 | -0.0506065 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0503325 |
| VIM | vimentin | -0.0501257 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0500368 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0496414 |
| S100A6 | S100 calcium binding protein A6 | -0.0494346 |
| FTL | ferritin, light polypeptide | -0.0483103 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0475813 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0472347 |
| RBM39 | RNA binding motif protein 39 | -0.0468411 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0460294 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0458685 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0449164 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0446013 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0442698 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0438835 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | -0.0434545 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0430811 |
| ITGA6 | integrin, alpha 6 | -0.041906 |
| FAM107B | family with sequence similarity 107, member B | -0.039998 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.039493 |
| RPS6 | ribosomal protein S6 | -0.0391933 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0389153 |
| SQSTM1 | sequestosome 1 | -0.038187 |
| S100A4 | S100 calcium binding protein A4 | -0.0381179 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0380514 |
| MXD1 | MAX dimerization protein 1 | -0.0380091 |
| RIOK3 | RIO kinase 3 | -0.0373375 |
| OGA | O-GlcNAcase | -0.0373346 |
| EPCAM | epithelial cell adhesion molecule | -0.0370915 |
| FAM13A | family with sequence similarity 13, member A | -0.0369908 |
| PERP | PERP, TP53 apoptosis effector | -0.0368469 |
| RPL31 | ribosomal protein L31 | -0.0367869 |
| OSBPL3 | oxysterol binding protein-like 3 | -0.0367661 |
| CD2AP | CD2-associated protein | -0.0361076 |
| TMBIM1 | transmembrane BAX inhibitor motif containing 1 | -0.0357954 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0355331 |
| RPL8 | ribosomal protein L8 | -0.0345809 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.034063 |
| WASF2 | WAS protein family, member 2 | -0.0338829 |
| EMP1 | epithelial membrane protein 1 | -0.0338273 |
| USP3 | ubiquitin specific peptidase 3 | -0.0333318 |
| PLAUR | plasminogen activator, urokinase receptor | -0.033272 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0330122 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0328014 |
| PARP8 | poly (ADP-ribose) polymerase family, member 8 | -0.0327626 |
| RPLP1 | ribosomal protein, large, P1 | -0.0327008 |
| RPL11 | ribosomal protein L11 | -0.0325699 |
| PGK1 | phosphoglycerate kinase 1 | -0.0323 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0319271 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0318001 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0317349 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0316604 |
| RPL37A | ribosomal protein L37a | -0.0316216 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0315656 |
| IER3 | immediate early response 3 | -0.0315104 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0314852 |
| NEK7 | NIMA-related kinase 7 | -0.0313699 |
| RPS8 | ribosomal protein S8 | -0.0312912 |
| RPL12 | ribosomal protein L12 | -0.0312193 |
| HIBADH | 3-hydroxyisobutyrate dehydrogenase | -0.030793 |
| ANLN | anillin, actin binding protein | -0.0306934 |
| RPS13 | ribosomal protein S13 | -0.0305256 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0304815 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0302699 |
| RPS24 | ribosomal protein S24 | -0.0301441 |
| TOP1 | topoisomerase (DNA) I | -0.0301388 |
| RPL34 | ribosomal protein L34 | -0.0301062 |
| TMEM41B | transmembrane protein 41B | -0.0299837 |
| RNF145 | ring finger protein 145 | -0.0298269 |
| RPS25 | ribosomal protein S25 | -0.0297152 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0295746 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0292436 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.029086 |
| RPS21 | ribosomal protein S21 | -0.0289813 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | -0.0287048 |
| GOLGA4 | golgin A4 | -0.028632 |
| RPS27A | ribosomal protein S27a | -0.0280824 |
| RPLP0 | ribosomal protein, large, P0 | -0.0276377 |
| FOXO3 | forkhead box O3 | -0.027625 |
