| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.136679 |
| POTEF | POTE ankyrin domain family, member F | 0.110103 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.0969396 |
| ENO1 | enolase 1, (alpha) | 0.0938952 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0795816 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0785569 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0781186 |
| ACTG1 | actin gamma 1 | 0.0753192 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0723676 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0695722 |
| CENPF | centromere protein F, 350/400kDa | 0.0642086 |
| LDHA | lactate dehydrogenase A | 0.052456 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0490093 |
| AHNAK | AHNAK nucleoprotein | 0.0468404 |
| ACTN1 | actinin, alpha 1 | 0.046537 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.046497 |
| MT2A | metallothionein 2A | 0.0454557 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0448352 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0437906 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0417025 |
| DST | dystonin | 0.0384005 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0366284 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0344585 |
| RPL3 | ribosomal protein L3 | 0.033336 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0332984 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.0326774 |
| PLIN2 | perilipin 2 | 0.0325512 |
| PCDH7 | protocadherin 7 | 0.032379 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.0323657 |
| MCL1 | myeloid cell leukemia 1 | 0.0315487 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0313425 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0310612 |
| ZYX | zyxin | 0.0308502 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.030754 |
| TAGLN2 | transgelin 2 | 0.0305702 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0298744 |
| TPR | translocated promoter region, nuclear basket protein | 0.0295418 |
| APP | amyloid beta (A4) precursor protein | 0.0293989 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0290481 |
| FN1 | fibronectin 1 | 0.0273789 |
| FMN1 | formin 1 | 0.0273662 |
| AFAP1 | actin filament associated protein 1 | 0.0271876 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0270635 |
| PCBP2 | poly(rC) binding protein 2 | 0.0265858 |
| TSC22D1 | TSC22 domain family, member 1 | 0.025955 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.025821 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0255107 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0253448 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0252463 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0251931 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0250653 |
| NOTCH2 | notch 2 | 0.0246241 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0245712 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0245632 |
| GAS7 | growth arrest-specific 7 | 0.0243666 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0243078 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0240765 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0234766 |
| DSTN | destrin (actin depolymerizing factor) | 0.0234297 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0234136 |
| NRP2 | neuropilin 2 | 0.0229292 |
| LAMB1 | laminin, beta 1 | 0.0228039 |
| SETBP1 | SET binding protein 1 | 0.0223184 |
| MSN | moesin | 0.0220636 |
| TLE4 | transducin-like enhancer of split 4 | 0.0216892 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0215984 |
| ASPH | aspartate beta-hydroxylase | 0.0215069 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0213662 |
| DOCK4 | dedicator of cytokinesis 4 | 0.0213491 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0211077 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.021096 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0205666 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0204885 |
| MKI67 | marker of proliferation Ki-67 | 0.0203217 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0201103 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0197958 |
| FAT1 | FAT atypical cadherin 1 | 0.0194851 |
| BRD2 | bromodomain containing 2 | 0.0192629 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0192531 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.019148 |
| SON | SON DNA binding protein | 0.0191432 |
| YAP1 | Yes-associated protein 1 | 0.0189429 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0187386 |
| TMEM178B | transmembrane protein 178B | 0.0187374 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0185785 |
| BAZ1B | bromodomain adjacent to zinc finger domain, 1B | 0.0185473 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.018512 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0181587 |
| AMOTL1 | angiomotin like 1 | 0.0181197 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0180903 |
| EFCAB13 | EF-hand calcium binding domain 13 | 0.0180256 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0180235 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0179939 |
| NAV1 | neuron navigator 1 | 0.0178323 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0177967 |
| UHMK1 | U2AF homology motif (UHM) kinase 1 | 0.0177539 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0174405 |
| PRKD1 | protein kinase D1 | 0.0171278 |
| VCL | vinculin | 0.0170227 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0169747 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.363995 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.246927 |
| NDRG1 | N-myc downstream regulated 1 | -0.122668 |
| NLGN1 | neuroligin 1 | -0.113811 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.108443 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0988777 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0988685 |
| VGF | VGF nerve growth factor inducible | -0.0984045 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0895301 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0888805 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | -0.0761717 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0748796 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.070657 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0704599 |
| GDF15 | growth differentiation factor 15 | -0.0654909 |
| HLA-B | major histocompatibility complex, class I, B | -0.0640982 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0624958 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0623624 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0596164 |
| IER3 | immediate early response 3 | -0.0559283 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0551003 |
| TNFRSF19 | tumor necrosis factor receptor superfamily, member 19 | -0.0544435 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0540347 |
| PTMA | prothymosin, alpha | -0.0529819 |
| PRELID2 | PRELI domain containing 2 | -0.0509789 |
| PTK2 | protein tyrosine kinase 2 | -0.0506618 |
| TMSB10 | thymosin beta 10 | -0.0497105 |
| RUNX1 | runt-related transcription factor 1 | -0.0492041 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0480358 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0478758 |
| SCFD2 | sec1 family domain containing 2 | -0.0476958 |
| EHBP1 | EH domain binding protein 1 | -0.0464249 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0460153 |
| NBAS | neuroblastoma amplified sequence | -0.0458064 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0440184 |
| CD109 | CD109 molecule | -0.0438885 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0438338 |
| TMEM123 | transmembrane protein 123 | -0.0435442 |
| CALU | calumenin | -0.0434527 |
| FNDC3B | fibronectin type III domain containing 3B | -0.042904 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.042748 |
| PHF21A | PHD finger protein 21A | -0.0427233 |
| RHEB | Ras homolog enriched in brain | -0.0425043 |
| PTCHD4 | patched domain containing 4 | -0.0420978 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | -0.0410229 |
| OXR1 | oxidation resistance 1 | -0.0409715 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0407954 |
| RPLP1 | ribosomal protein, large, P1 | -0.0407455 |
| PGK1 | phosphoglycerate kinase 1 | -0.0406857 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0397961 |
| WDR45B | WD repeat domain 45B | -0.0392106 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0383876 |
| GNAS | GNAS complex locus | -0.0382763 |
| NAV2 | neuron navigator 2 | -0.0381745 |
| SBF2 | SET binding factor 2 | -0.0380288 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.037911 |
| FUS | FUS RNA binding protein | -0.0376865 |
| CDK14 | cyclin-dependent kinase 14 | -0.0376754 |
| CDC73 | cell division cycle 73 | -0.0375214 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0373572 |
| RPL35A | ribosomal protein L35a | -0.0356105 |
| S100A6 | S100 calcium binding protein A6 | -0.0349301 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0348665 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.034825 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0345793 |
| RPS24 | ribosomal protein S24 | -0.0344104 |
| DENND1A | DENN/MADD domain containing 1A | -0.0341659 |
| EGR1 | early growth response 1 | -0.0336701 |
| PDE10A | phosphodiesterase 10A | -0.0327213 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0326468 |
| TRIM2 | tripartite motif containing 2 | -0.0322967 |
| COPA | coatomer protein complex, subunit alpha | -0.0322949 |
| CTSD | cathepsin D | -0.0320977 |
| PYGB | phosphorylase, glycogen; brain | -0.0319351 |
| RFX7 | regulatory factor X, 7 | -0.0317712 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0317127 |
| RPL37A | ribosomal protein L37a | -0.0313048 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0310211 |
| OSMR | oncostatin M receptor | -0.0309899 |
| CHSY1 | chondroitin sulfate synthase 1 | -0.0304872 |
| GOLGA4 | golgin A4 | -0.0304677 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0303793 |
| SPAG9 | sperm associated antigen 9 | -0.0302684 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0301958 |
| A2M | alpha-2-macroglobulin | -0.0300756 |
| HELZ | helicase with zinc finger | -0.0300648 |
| NAV3 | neuron navigator 3 | -0.0299273 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0297255 |
| PARVB | parvin, beta | -0.0293751 |
| NPR2 | natriuretic peptide receptor 2 | -0.0293401 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0292339 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0290942 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0289603 |
| TMEM263 | transmembrane protein 263 | -0.0288342 |
| HBP1 | HMG-box transcription factor 1 | -0.028772 |
| RNF24 | ring finger protein 24 | -0.0283703 |
| POM121 | POM121 transmembrane nucleoporin | -0.028292 |
| RAB1A | RAB1A, member RAS oncogene family | -0.028235 |
| RPS6 | ribosomal protein S6 | -0.028182 |
| TPD52 | tumor protein D52 | -0.0280628 |
