| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | 0.158698 |
| B2M | beta-2-microglobulin | 0.133221 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.124351 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.117045 |
| ENO1 | enolase 1, (alpha) | 0.10091 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0942883 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0870958 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0830771 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0828951 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0755875 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0688242 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0613086 |
| MT1E | metallothionein 1E | 0.0567545 |
| RPL23 | ribosomal protein L23 | 0.0564378 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0552778 |
| KRT19 | keratin 19, type I | 0.0513017 |
| CP | ceruloplasmin (ferroxidase) | 0.0502982 |
| LDHA | lactate dehydrogenase A | 0.0497022 |
| RPS3 | ribosomal protein S3 | 0.0489041 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0476052 |
| RPS8 | ribosomal protein S8 | 0.047156 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0465531 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0451727 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0443521 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0440608 |
| POTEF | POTE ankyrin domain family, member F | 0.0437022 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0435697 |
| HLA-A | major histocompatibility complex, class I, A | 0.0432674 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0429586 |
| LCN2 | lipocalin 2 | 0.0427366 |
| APP | amyloid beta (A4) precursor protein | 0.0420128 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0407187 |
| MCL1 | myeloid cell leukemia 1 | 0.0397507 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0376346 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0374259 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0369216 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0367074 |
| RPL3 | ribosomal protein L3 | 0.0361962 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0355767 |
| NTN4 | netrin 4 | 0.0348194 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | 0.0344232 |
| HLA-B | major histocompatibility complex, class I, B | 0.0343375 |
| PCBP2 | poly(rC) binding protein 2 | 0.0338951 |
| SP100 | SP100 nuclear antigen | 0.0334587 |
| PLAU | plasminogen activator, urokinase | 0.0333356 |
| RPL4 | ribosomal protein L4 | 0.0332827 |
| TMSB4X | thymosin beta 4, X-linked | 0.0326198 |
| HDAC9 | histone deacetylase 9 | 0.032414 |
| IFITM1 | interferon induced transmembrane protein 1 | 0.032346 |
| ADAR | adenosine deaminase, RNA-specific | 0.0320929 |
| VIM | vimentin | 0.0314359 |
| CFB | complement factor B | 0.0313231 |
| RPL19 | ribosomal protein L19 | 0.0304427 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0303387 |
| FTL | ferritin, light polypeptide | 0.0303314 |
| RPL37A | ribosomal protein L37a | 0.0299457 |
| RPS12 | ribosomal protein S12 | 0.0294259 |
| OPTN | optineurin | 0.0292246 |
| RACK1 | receptor for activated C kinase 1 | 0.0289931 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0287727 |
| LAMB3 | laminin, beta 3 | 0.0284736 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0283604 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0282265 |
| MX1 | MX dynamin-like GTPase 1 | 0.0274179 |
| TGM2 | transglutaminase 2 | 0.0270589 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0269398 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0267017 |
| BICC1 | BicC family RNA binding protein 1 | 0.0263283 |
| YBX1 | Y box binding protein 1 | 0.0262476 |
| MT1X | metallothionein 1X | 0.0261635 |
| TXNIP | thioredoxin interacting protein | 0.0256942 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0250707 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0250284 |
| RPLP1 | ribosomal protein, large, P1 | 0.0246983 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0246766 |
| TACSTD2 | tumor-associated calcium signal transducer 2 | 0.0246522 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0246024 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0243838 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0241516 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0241247 |
| PLK2 | polo-like kinase 2 | 0.0241034 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0238324 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0238101 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0236234 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0233053 |
| IFITM3 | interferon induced transmembrane protein 3 | 0.0232131 |
| ACTG1 | actin gamma 1 | 0.023207 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0231628 |
| RPL37 | ribosomal protein L37 | 0.0231357 |
| ARHGAP42 | Rho GTPase activating protein 42 | 0.0231353 |
| RPS2 | ribosomal protein S2 | 0.022681 |
| IFI44L | interferon-induced protein 44-like | 0.0223272 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0220584 |
| C3 | complement component 3 | 0.0220544 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0220381 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0218349 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0217794 |
| SFTPA2 | surfactant protein A2 | 0.0217176 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0217009 |
| PDZD8 | PDZ domain containing 8 | 0.0215976 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | -0.129177 |
| DTNA | dystrobrevin, alpha | -0.116403 |
| FNDC3B | fibronectin type III domain containing 3B | -0.112124 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.100688 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0987677 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0976391 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0922321 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.091998 |
| FLNB | filamin B, beta | -0.0915654 |
| SPAG9 | sperm associated antigen 9 | -0.0900347 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0781426 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0758994 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0750354 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0737575 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0727497 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0703105 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0698476 |
| LAMC2 | laminin, gamma 2 | -0.0686332 |
| MEF2A | myocyte enhancer factor 2A | -0.0673129 |
| NCKAP5 | NCK-associated protein 5 | -0.0656749 |
| UBC | ubiquitin C | -0.0650354 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0649992 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0634667 |
| PARD3 | par-3 family cell polarity regulator | -0.0632488 |
| ACTN4 | actinin, alpha 4 | -0.0623639 |
| LMO7 | LIM domain 7 | -0.0619388 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0611231 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0586205 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0581457 |
| PRKCA | protein kinase C, alpha | -0.0576366 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.056623 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.056457 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.055363 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0541361 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0533613 |
| DST | dystonin | -0.0525917 |
| HMGA2 | high mobility group AT-hook 2 | -0.0524878 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0514234 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0507811 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.050474 |
| ASPH | aspartate beta-hydroxylase | -0.0502508 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0501586 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.049848 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0492687 |
| MMP7 | matrix metallopeptidase 7 | -0.0489798 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0489713 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0481979 |
| FGD6 | FYVE, RhoGEF and PH domain containing 6 | -0.0476676 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0472981 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0471543 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0457465 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0453232 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0441873 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0434157 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0433961 |
| HELZ | helicase with zinc finger | -0.0433653 |
| CCNY | cyclin Y | -0.042876 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0420768 |
| RAD51B | RAD51 paralog B | -0.0412921 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | -0.0409499 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0405499 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0398018 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0390983 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0390315 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0382895 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0376288 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0375426 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0375385 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0373744 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0371207 |
| MCU | mitochondrial calcium uniporter | -0.0358484 |
| RASA2 | RAS p21 protein activator 2 | -0.0356745 |
| ATXN1 | ataxin 1 | -0.0356337 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0354998 |
| VCL | vinculin | -0.0354858 |
| SLCO3A1 | solute carrier organic anion transporter family, member 3A1 | -0.0349766 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0349278 |
| SMYD3 | SET and MYND domain containing 3 | -0.0342158 |
| RCOR1 | REST corepressor 1 | -0.0341178 |
| RRBP1 | ribosome binding protein 1 | -0.0340473 |
| HPCAL1 | hippocalcin-like 1 | -0.0339256 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0338951 |
| OGA | O-GlcNAcase | -0.033809 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0336518 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0336246 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0334763 |
| PCDH7 | protocadherin 7 | -0.0332911 |
| FOXO3 | forkhead box O3 | -0.0331636 |
| PFKP | phosphofructokinase, platelet | -0.0328841 |
| NUMB | numb homolog (Drosophila) | -0.0328094 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0327325 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0326408 |
| RREB1 | ras responsive element binding protein 1 | -0.0325685 |
| RTN4 | reticulon 4 | -0.0324882 |
| CLIC4 | chloride intracellular channel 4 | -0.0324626 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0324433 |
| TMSB10 | thymosin beta 10 | -0.0318687 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0316855 |
| YEATS2 | YEATS domain containing 2 | -0.0316851 |
| CMIP | c-Maf inducing protein | -0.0315873 |
