| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.232103 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.117435 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0823715 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0601965 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0525785 |
| PTMA | prothymosin, alpha | 0.0454039 |
| ACTG1 | actin gamma 1 | 0.0436681 |
| PCBP2 | poly(rC) binding protein 2 | 0.0435644 |
| APP | amyloid beta (A4) precursor protein | 0.0421653 |
| VIM | vimentin | 0.0421222 |
| CENPF | centromere protein F, 350/400kDa | 0.0414981 |
| TBX2 | T-box 2 | 0.0392861 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0375693 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0359652 |
| POTEF | POTE ankyrin domain family, member F | 0.0358437 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0355794 |
| RPL3 | ribosomal protein L3 | 0.0332374 |
| PTEN | phosphatase and tensin homolog | 0.0309907 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0306049 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0304718 |
| SET | SET nuclear proto-oncogene | 0.0302569 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0284553 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0280846 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0278542 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0278244 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0272025 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0264043 |
| ENO1 | enolase 1, (alpha) | 0.0260513 |
| SCG2 | secretogranin II | 0.026006 |
| HMGB2 | high mobility group box 2 | 0.0259379 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0255057 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0254584 |
| PCM1 | pericentriolar material 1 | 0.0248496 |
| TLE4 | transducin-like enhancer of split 4 | 0.0243938 |
| MMP2 | matrix metallopeptidase 2 | 0.0239314 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0228932 |
| MKI67 | marker of proliferation Ki-67 | 0.0225867 |
| RPS3 | ribosomal protein S3 | 0.0216129 |
| B2M | beta-2-microglobulin | 0.0214874 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0214155 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0213319 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.020773 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0206459 |
| RPL23 | ribosomal protein L23 | 0.0203535 |
| RACK1 | receptor for activated C kinase 1 | 0.0202983 |
| RUNX1 | runt-related transcription factor 1 | 0.020214 |
| STC1 | stanniocalcin 1 | 0.0188118 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0178486 |
| HSPA8 | heat shock 70kDa protein 8 | 0.017707 |
| DDX24 | DEAD (Asp-Glu-Ala-Asp) box helicase 24 | 0.0175813 |
| TLN1 | talin 1 | 0.0175728 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0173577 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0171519 |
| NEK1 | NIMA-related kinase 1 | 0.0168875 |
| PELO | pelota homolog (Drosophila) | 0.0168344 |
| ADAR | adenosine deaminase, RNA-specific | 0.0168077 |
| ZNF146 | zinc finger protein 146 | 0.0167938 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0165278 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0164489 |
| PLPP1 | phospholipid phosphatase 1 | 0.0163959 |
| CBX3 | chromobox homolog 3 | 0.0163592 |
| MED13L | mediator complex subunit 13-like | 0.0163535 |
| CCNL1 | cyclin L1 | 0.0163305 |
| RAB30 | RAB30, member RAS oncogene family | 0.0162127 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0162082 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0159923 |
| ZBTB18 | zinc finger and BTB domain containing 18 | 0.0158601 |
| CCNY | cyclin Y | 0.0157528 |
| YBX1 | Y box binding protein 1 | 0.0156937 |
| RPL7 | ribosomal protein L7 | 0.0154842 |
| RPS4X | ribosomal protein S4, X-linked | 0.0151329 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0151239 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.015074 |
| WNT5A | wingless-type MMTV integration site family, member 5A | 0.0150457 |
| GREM2 | gremlin 2, DAN family BMP antagonist | 0.0150315 |
| BRD2 | bromodomain containing 2 | 0.0148881 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0148863 |
| MATR3 | matrin 3 | 0.0148616 |
| DHX40 | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 0.0148466 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0148005 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0147391 |
| GOLGA4 | golgin A4 | 0.0146574 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0145915 |
| SNAP25 | synaptosomal-associated protein, 25kDa | 0.0145881 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0145538 |
| RNASEH2A | ribonuclease H2, subunit A | 0.014534 |
| DGKH | diacylglycerol kinase, eta | 0.0143295 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0142969 |
| TAF7 | TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 55kDa | 0.0142389 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0138327 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0138011 |
| HAS2 | hyaluronan synthase 2 | 0.0136149 |
| SCARB2 | scavenger receptor class B, member 2 | 0.0134344 |
| RGS5 | regulator of G-protein signaling 5 | 0.0133903 |
| ZNF331 | zinc finger protein 331 | 0.0133782 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0133362 |
| ACTN1 | actinin, alpha 1 | 0.0131612 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | 0.0131561 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0131559 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0131247 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.246191 |
| LSAMP | limbic system-associated membrane protein | -0.212474 |
| NRG1 | neuregulin 1 | -0.194925 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0950231 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0804713 |
| PRKCA | protein kinase C, alpha | -0.0760662 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0625293 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0548267 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0536105 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.053352 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0527836 |
| NREP | neuronal regeneration related protein | -0.0522675 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0512369 |
| EGR1 | early growth response 1 | -0.0508721 |
| RAD51B | RAD51 paralog B | -0.0506459 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0506384 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0505443 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0489839 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0483858 |
| ZNF804A | zinc finger protein 804A | -0.0460592 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0460366 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0441131 |
| GPC5 | glypican 5 | -0.0428772 |
| CUX1 | cut-like homeobox 1 | -0.0418972 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | -0.0416795 |
| FMN1 | formin 1 | -0.0414265 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0412463 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0411713 |
| BPTF | bromodomain PHD finger transcription factor | -0.0405086 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0398812 |
| RPL38 | ribosomal protein L38 | -0.0397576 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0387738 |
| COL1A1 | collagen, type I, alpha 1 | -0.0386108 |
| RPL35A | ribosomal protein L35a | -0.0358435 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0355196 |
| FRMD4A | FERM domain containing 4A | -0.0335141 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0317151 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0315516 |
| SMYD3 | SET and MYND domain containing 3 | -0.0311331 |
| DPH6 | diphthamine biosynthesis 6 | -0.0309453 |
| MSI2 | musashi RNA-binding protein 2 | -0.0299308 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0288228 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0284871 |
| MEIS2 | Meis homeobox 2 | -0.0283718 |
| TCF12 | transcription factor 12 | -0.0283303 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0282952 |
| RPS24 | ribosomal protein S24 | -0.0282887 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0277027 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0276279 |
| AUTS2 | autism susceptibility candidate 2 | -0.0269374 |
| MAPK10 | mitogen-activated protein kinase 10 | -0.0269238 |
| MED13 | mediator complex subunit 13 | -0.0268329 |
| FHIT | fragile histidine triad | -0.0267987 |
| NDRG1 | N-myc downstream regulated 1 | -0.0267536 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0264756 |
| PARD3 | par-3 family cell polarity regulator | -0.0264552 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0264394 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0260843 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.026052 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0259127 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0255939 |
| VCL | vinculin | -0.0255373 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0250288 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0250229 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.024871 |
| SYT1 | synaptotagmin I | -0.0245651 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.024158 |
| RPS8 | ribosomal protein S8 | -0.0240535 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0240344 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0235772 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0235687 |
| CADM1 | cell adhesion molecule 1 | -0.0232396 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0232327 |
| RPLP1 | ribosomal protein, large, P1 | -0.0232308 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0230597 |
| CDK12 | cyclin-dependent kinase 12 | -0.0230035 |
| CEP350 | centrosomal protein 350kDa | -0.0227829 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0226306 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0223949 |
| CNTN4 | contactin 4 | -0.0223155 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0223043 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0221053 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.021749 |
| RPL34 | ribosomal protein L34 | -0.021653 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0214675 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0213045 |
| IER3 | immediate early response 3 | -0.0210196 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0204643 |
| SP100 | SP100 nuclear antigen | -0.0204613 |
| CDH13 | cadherin 13 | -0.0202682 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0201466 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.019968 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | -0.0199005 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0198966 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.019764 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.019665 |
| COMMD10 | COMM domain containing 10 | -0.0196108 |
| PTK2 | protein tyrosine kinase 2 | -0.0195046 |
| HELZ | helicase with zinc finger | -0.0194845 |
| AOPEP | aminopeptidase O (putative) | -0.0193862 |
