| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.122092 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.11759 |
| INTS6 | integrator complex subunit 6 | 0.0965719 |
| LMO7 | LIM domain 7 | 0.0897443 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0857041 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0846837 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0839394 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0839222 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0817239 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0788105 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0692592 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0689392 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0562637 |
| SMAD3 | SMAD family member 3 | 0.0551746 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0512793 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0500481 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0496447 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0483728 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0476359 |
| PLSCR2 | phospholipid scramblase 2 | 0.0463264 |
| MUC13 | mucin 13, cell surface associated | 0.0446552 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0441127 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0438547 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0436274 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0426414 |
| STS | steroid sulfatase (microsomal), isozyme S | 0.0403335 |
| RNF213 | ring finger protein 213 | 0.0401174 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0389889 |
| AREG | amphiregulin | 0.0374517 |
| EREG | epiregulin | 0.0371732 |
| MYO1E | myosin IE | 0.0371432 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0371166 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0351892 |
| MX1 | MX dynamin-like GTPase 1 | 0.0344559 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.034432 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0338575 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0334286 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0330009 |
| MYO10 | myosin X | 0.0329426 |
| TUFT1 | tuftelin 1 | 0.0328575 |
| FAT1 | FAT atypical cadherin 1 | 0.0322734 |
| LCN2 | lipocalin 2 | 0.0317236 |
| TMC5 | transmembrane channel-like 5 | 0.0307848 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | 0.0306883 |
| FHL2 | four and a half LIM domains 2 | 0.0300818 |
| PDZD8 | PDZ domain containing 8 | 0.0299962 |
| ETV6 | ets variant 6 | 0.0297543 |
| SIK3 | SIK family kinase 3 | 0.0296598 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0294386 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0294361 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | 0.0292474 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0284361 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0279432 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0277743 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0271389 |
| POTEF | POTE ankyrin domain family, member F | 0.027011 |
| TIPARP | TCDD-inducible poly(ADP-ribose) polymerase | 0.0264579 |
| PHF3 | PHD finger protein 3 | 0.0264102 |
| TOX3 | TOX high mobility group box family member 3 | 0.026347 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.0262798 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0259229 |
| VMP1 | vacuole membrane protein 1 | 0.0255314 |
| DST | dystonin | 0.0252843 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0250071 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0248809 |
| CDHR2 | cadherin-related family member 2 | 0.0244486 |
| ACTG1 | actin gamma 1 | 0.0242989 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0238968 |
| ADORA2B | adenosine A2b receptor | 0.0237103 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0234989 |
| SET | SET nuclear proto-oncogene | 0.0231873 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0231729 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0230907 |
| APP | amyloid beta (A4) precursor protein | 0.023075 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | 0.0224791 |
| ITGA6 | integrin, alpha 6 | 0.0222497 |
| TMEM65 | transmembrane protein 65 | 0.0217755 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0217362 |
| SORBS1 | sorbin and SH3 domain containing 1 | 0.0216322 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0215643 |
| FNIP2 | folliculin interacting protein 2 | 0.0213331 |
| FHIT | fragile histidine triad | 0.0213132 |
| WEE1 | WEE1 G2 checkpoint kinase | 0.0211901 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0211814 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0210849 |
| YAP1 | Yes-associated protein 1 | 0.0210656 |
| EPHB2 | EPH receptor B2 | 0.0206654 |
| MYO5B | myosin VB | 0.0206225 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0203906 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0200744 |
| ACTN1 | actinin, alpha 1 | 0.0197424 |
| JAG1 | jagged 1 | 0.019534 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0194955 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | 0.0194737 |
| MSI2 | musashi RNA-binding protein 2 | 0.0194318 |
| RBM47 | RNA binding motif protein 47 | 0.0187963 |
| KYNU | kynureninase | 0.0187279 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0186051 |
| SH3PXD2A | SH3 and PX domains 2A | 0.018592 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0184971 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.14102 |
| B2M | beta-2-microglobulin | -0.12693 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.116816 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.108312 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0996526 |
| HLA-B | major histocompatibility complex, class I, B | -0.0864961 |
| NDRG1 | N-myc downstream regulated 1 | -0.0817413 |
| PTMA | prothymosin, alpha | -0.0791365 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0753121 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0730543 |
| EGR1 | early growth response 1 | -0.0650004 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0641379 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0621316 |
| H1-0 | H1.0 linker histone | -0.0611163 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0595586 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0565803 |
| NCKAP5 | NCK-associated protein 5 | -0.056383 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0558305 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0545722 |
| DIAPH3 | diaphanous-related formin 3 | -0.0510783 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0508385 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0505695 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0503641 |
| AHI1 | Abelson helper integration site 1 | -0.0500397 |
| TMSB10 | thymosin beta 10 | -0.0472392 |
| SQSTM1 | sequestosome 1 | -0.0462642 |
| RPL35A | ribosomal protein L35a | -0.0462008 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.045742 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0457227 |
| RPL34 | ribosomal protein L34 | -0.0453009 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0452666 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0441463 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0438764 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0437931 |
| HLA-E | major histocompatibility complex, class I, E | -0.0434199 |
| MKI67 | marker of proliferation Ki-67 | -0.0428357 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0416121 |
| MT2A | metallothionein 2A | -0.0410432 |
| XAF1 | XIAP associated factor 1 | -0.0406951 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0397615 |
| TMPRSS4 | transmembrane protease, serine 4 | -0.0387048 |
| RPS24 | ribosomal protein S24 | -0.0382232 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0382141 |
| HLA-C | major histocompatibility complex, class I, C | -0.0382 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0376118 |
| HLA-A | major histocompatibility complex, class I, A | -0.0352606 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0351952 |
| FOXO3 | forkhead box O3 | -0.0351468 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.0350846 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0339293 |
| ERBIN | erbb2 interacting protein | -0.0338209 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0337854 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0329855 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0329322 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0326663 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0320605 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0319408 |
| PERP | PERP, TP53 apoptosis effector | -0.0317193 |
| SSH2 | slingshot protein phosphatase 2 | -0.0315652 |
| GNAS | GNAS complex locus | -0.0313999 |
| FMN1 | formin 1 | -0.0313259 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0308768 |
| NF1 | neurofibromin 1 | -0.0307266 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0307041 |
| APOL1 | apolipoprotein L, 1 | -0.0306372 |
| CENPF | centromere protein F, 350/400kDa | -0.0306259 |
| SYT1 | synaptotagmin I | -0.0304933 |
| RPS6 | ribosomal protein S6 | -0.0304024 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0302757 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0299043 |
| RPL7L1 | ribosomal protein L7-like 1 | -0.0298502 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0298501 |
| CENPP | centromere protein P | -0.0297814 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0297008 |
| RRBP1 | ribosome binding protein 1 | -0.0295312 |
| SLC7A1 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 | -0.0291476 |
| RPL23 | ribosomal protein L23 | -0.0288848 |
| RPL12 | ribosomal protein L12 | -0.0286942 |
| RPL26 | ribosomal protein L26 | -0.0285419 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0284149 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0283865 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0283634 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0282851 |
| RUNX1 | runt-related transcription factor 1 | -0.0281303 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0280297 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0279161 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0279122 |
| RPL11 | ribosomal protein L11 | -0.0278059 |
| S100A6 | S100 calcium binding protein A6 | -0.0277243 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0277116 |
| FOXP1 | forkhead box P1 | -0.0275974 |
| RNF43 | ring finger protein 43 | -0.0273856 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0273853 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0273225 |
| UBAC2 | UBA domain containing 2 | -0.0272511 |
| UBC | ubiquitin C | -0.0266969 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0266422 |
| PRELID2 | PRELI domain containing 2 | -0.0266242 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0265227 |
| PTEN | phosphatase and tensin homolog | -0.0263807 |
