| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | ETC-206 perturbation in H4 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the ETC-206_H4 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.242736 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.156727 |
| ASPH | aspartate beta-hydroxylase | 0.145351 |
| AHNAK | AHNAK nucleoprotein | 0.100003 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0958482 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0662138 |
| CD44 | CD44 molecule (Indian blood group) | 0.0606248 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0597344 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0569819 |
| VCL | vinculin | 0.0546509 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0545915 |
| KYNU | kynureninase | 0.051192 |
| ENO1 | enolase 1, (alpha) | 0.0448307 |
| GLIS3 | GLIS family zinc finger 3 | 0.0422331 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0383804 |
| BBS9 | Bardet-Biedl syndrome 9 | 0.0379519 |
| APP | amyloid beta (A4) precursor protein | 0.0374364 |
| UCHL1 | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 0.0363996 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0359987 |
| PDLIM5 | PDZ and LIM domain 5 | 0.035584 |
| MYO10 | myosin X | 0.0353787 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.035332 |
| NAV1 | neuron navigator 1 | 0.0330004 |
| ITGB3BP | integrin beta 3 binding protein (beta3-endonexin) | 0.032543 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0323388 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0323128 |
| DST | dystonin | 0.0319651 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0316914 |
| SATB2 | SATB homeobox 2 | 0.0305531 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0304343 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0303924 |
| LDHA | lactate dehydrogenase A | 0.0303645 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0291489 |
| COL12A1 | collagen, type XII, alpha 1 | 0.0289396 |
| HMGA2 | high mobility group AT-hook 2 | 0.0287813 |
| ACTN1 | actinin, alpha 1 | 0.0284235 |
| PHF14 | PHD finger protein 14 | 0.0278831 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0274972 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0274231 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0274007 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0272722 |
| PLEC | plectin | 0.026957 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0268689 |
| SMAD3 | SMAD family member 3 | 0.0262487 |
| TPM3 | tropomyosin 3 | 0.0261822 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.026107 |
| CDK14 | cyclin-dependent kinase 14 | 0.0260607 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0260596 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0253724 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0248837 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0248064 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0245717 |
| VEGFC | vascular endothelial growth factor C | 0.0238776 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0235767 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0235702 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0235594 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0235164 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0234758 |
| COL5A1 | collagen, type V, alpha 1 | 0.0232253 |
| ZNF804A | zinc finger protein 804A | 0.0230041 |
| ARHGAP24 | Rho GTPase activating protein 24 | 0.0228987 |
| TLN1 | talin 1 | 0.0225949 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0219495 |
| FLNA | filamin A, alpha | 0.0216713 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0215486 |
| ANO6 | anoctamin 6 | 0.0212821 |
| FAM20C | family with sequence similarity 20, member C | 0.0211489 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0209078 |
| LAMB1 | laminin, beta 1 | 0.020678 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0204602 |
| POTEF | POTE ankyrin domain family, member F | 0.0201796 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0199523 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.019889 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0196972 |
| SETBP1 | SET binding protein 1 | 0.0196699 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0196552 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0195181 |
| FAT1 | FAT atypical cadherin 1 | 0.0194835 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0193989 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0191958 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0190158 |
| NAV3 | neuron navigator 3 | 0.0188188 |
| ZC3H12B | zinc finger CCCH-type containing 12B | 0.0187327 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0187278 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0186562 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0186517 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0185358 |
| TRPC1 | transient receptor potential cation channel, subfamily C, member 1 | 0.0182196 |
| INTS6 | integrator complex subunit 6 | 0.0181614 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0181504 |
| PRSS23 | protease, serine, 23 | 0.018141 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0178217 |
| USO1 | USO1 vesicle transport factor | 0.0177265 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0174971 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | 0.0174299 |
| PTK2 | protein tyrosine kinase 2 | 0.0172651 |
| IL6ST | interleukin 6 signal transducer | 0.0172361 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0171159 |
| SMYD3 | SET and MYND domain containing 3 | 0.0171084 |
| LOXL2 | lysyl oxidase-like 2 | 0.0169599 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.304619 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.206636 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.154816 |
| FTL | ferritin, light polypeptide | -0.149385 |
| TMSB10 | thymosin beta 10 | -0.135084 |
| NDRG1 | N-myc downstream regulated 1 | -0.117177 |
| GRB10 | growth factor receptor-bound protein 10 | -0.108196 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0950772 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0830434 |
| FAM13A | family with sequence similarity 13, member A | -0.0824666 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0794195 |
| PTMA | prothymosin, alpha | -0.0721236 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0684102 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0682741 |
| RPL35A | ribosomal protein L35a | -0.0638679 |
| RPS6 | ribosomal protein S6 | -0.0597375 |
| VIM | vimentin | -0.0591911 |
| FN1 | fibronectin 1 | -0.0560878 |
| GOLGA4 | golgin A4 | -0.053059 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0526396 |
| HELZ | helicase with zinc finger | -0.0520475 |
| RPLP1 | ribosomal protein, large, P1 | -0.0509768 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0508804 |
| B2M | beta-2-microglobulin | -0.0504466 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0502736 |
| MMP12 | matrix metallopeptidase 12 | -0.0489903 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0468099 |
| GNAS | GNAS complex locus | -0.0448984 |
| EGR1 | early growth response 1 | -0.0447391 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0440397 |
| RTN4 | reticulon 4 | -0.0433942 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0429455 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0420615 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0420604 |
| HLA-A | major histocompatibility complex, class I, A | -0.0410142 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0408248 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0406018 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0402336 |
| SPAG9 | sperm associated antigen 9 | -0.039924 |
| ADM | adrenomedullin | -0.0394246 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0392796 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0385626 |
| RPL34 | ribosomal protein L34 | -0.038062 |
| RPL28 | ribosomal protein L28 | -0.0376373 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.037424 |
| RPS8 | ribosomal protein S8 | -0.0370985 |
| SEC24A | SEC24 family member A | -0.0367837 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | -0.0362908 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.036205 |
| RLF | rearranged L-myc fusion | -0.0360459 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0359442 |
| FNIP1 | folliculin interacting protein 1 | -0.0356812 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0354889 |
| HIP1 | huntingtin interacting protein 1 | -0.0353058 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0351837 |
| WDR45B | WD repeat domain 45B | -0.0351556 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0350906 |
| SRP54 | signal recognition particle 54kDa | -0.0350474 |
| CADM1 | cell adhesion molecule 1 | -0.0346845 |
| EGFR | epidermal growth factor receptor | -0.0333441 |
| UBC | ubiquitin C | -0.0330925 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0323701 |
| USP3 | ubiquitin specific peptidase 3 | -0.0322736 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0320073 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0318316 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0318293 |
| IGF2 | insulin-like growth factor 2 | -0.0313868 |
| CD109 | CD109 molecule | -0.030576 |
| ZNF395 | zinc finger protein 395 | -0.030228 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0301994 |
| SQSTM1 | sequestosome 1 | -0.0300669 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0298807 |
| RPLP2 | ribosomal protein, large, P2 | -0.0296974 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.029256 |
| NUP58 | nucleoporin 58 | -0.0288512 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.028837 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0286332 |
| S100A6 | S100 calcium binding protein A6 | -0.0286045 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0283657 |
| NOP58 | NOP58 ribonucleoprotein | -0.0281746 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0280953 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0277775 |
| INSIG2 | insulin induced gene 2 | -0.0276493 |
| RNMT | RNA (guanine-7-) methyltransferase | -0.0275613 |
| RPS13 | ribosomal protein S13 | -0.0275434 |
| HLA-B | major histocompatibility complex, class I, B | -0.0273415 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | -0.0272122 |
| RPS25 | ribosomal protein S25 | -0.027168 |
| IER3 | immediate early response 3 | -0.0271278 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.027125 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0270397 |
| COPA | coatomer protein complex, subunit alpha | -0.0270116 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0269611 |
| RPS19 | ribosomal protein S19 | -0.0268678 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0265928 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | -0.0264024 |
| USP37 | ubiquitin specific peptidase 37 | -0.0262822 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0259797 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0257352 |
| DTNA | dystrobrevin, alpha | -0.0251062 |
